Click here to switch to the map view.

The map label for this gene is fur [H]

Identifier: 17229183

GI number: 17229183

Start: 2020071

End: 2020526

Strand: Reverse

Name: fur [H]

Synonym: all1691

Alternate gene names: 17229183

Gene position: 2020526-2020071 (Counterclockwise)

Preceding gene: 17229184

Following gene: 17229180

Centisome position: 31.5

GC content: 43.64

Gene sequence:

>456_bases
ATGACTGTCTACACAAATACTTCGCTCAAGGCAGAATTAAACGAAAGAGGCTGGCGTTTGACCCCTCAACGGGAAACTAT
CTTACATATCTTTCAAGAACTTCCTCAAGGCGAACACCTGAGTGCAGAAGATTTATATCATCGCTTGGAAGCTGACGGTG
AAGGAATCAGCCTTTCAACGATTTACCGGACGTTGAAGTTGATGGCTCGGATGGGGATTTTACGTGAACTGGAATTAGGC
GAAGGACACAAGCACTACGAAATTAACCAGCCTTATCCCCATCATCACCATCACCTAATTTGTGTCAAATGTAACTCTAC
TATTGAATTCAAAAACGATTCAATCTTAAAAATTGGGGCAAAAACTGCCCAGAAAGAAGGTTTTCACCTACTGGACTGCC
AAATGACAATTCATGCAGTCTGCCCCAAGTGCCAACGTGCGCTCATGCCACTTTAG

Upstream 100 bases:

>100_bases
TAAAAGTTTAATAAATATTCTCAATAAGCAATGTTTGTTGCAAATCACTCCAAATATTTGTTATATTCTCAATTAACAAG
CTTTGTTGAGAAAAATTAGT

Downstream 100 bases:

>100_bases
CACCTGGGTAAGATAACAAGAGGAAGTTACTCAATAATCCAAAAATGAAGTTTTGAGAAATTCCTGATTAGTCGTTATCG
GAGGTAAGCAAACTGTTAAG

Product: cell wall-binding protein Fur

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MTVYTNTSLKAELNERGWRLTPQRETILHIFQELPQGEHLSAEDLYHRLEADGEGISLSTIYRTLKLMARMGILRELELG
EGHKHYEINQPYPHHHHHLICVKCNSTIEFKNDSILKIGAKTAQKEGFHLLDCQMTIHAVCPKCQRALMPL

Sequences:

>Translated_151_residues
MTVYTNTSLKAELNERGWRLTPQRETILHIFQELPQGEHLSAEDLYHRLEADGEGISLSTIYRTLKLMARMGILRELELG
EGHKHYEINQPYPHHHHHLICVKCNSTIEFKNDSILKIGAKTAQKEGFHLLDCQMTIHAVCPKCQRALMPL
>Mature_150_residues
TVYTNTSLKAELNERGWRLTPQRETILHIFQELPQGEHLSAEDLYHRLEADGEGISLSTIYRTLKLMARMGILRELELGE
GHKHYEINQPYPHHHHHLICVKCNSTIEFKNDSILKIGAKTAQKEGFHLLDCQMTIHAVCPKCQRALMPL

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates genes involved in iron scavenging or photosynthetic electron transport [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=139, Percent_Identity=38.1294964028777, Blast_Score=84, Evalue=4e-18,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17421; Mature: 17290

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVYTNTSLKAELNERGWRLTPQRETILHIFQELPQGEHLSAEDLYHRLEADGEGISLST
CEEECCCCEEEEECCCCCEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHH
IYRTLKLMARMGILRELELGEGHKHYEINQPYPHHHHHLICVKCNSTIEFKNDSILKIGA
HHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEEEEECCEEEECCCCEEEECC
KTAQKEGFHLLDCQMTIHAVCPKCQRALMPL
CHHCCCCCEEEEHHHHHHHHCHHHHHHCCCC
>Mature Secondary Structure 
TVYTNTSLKAELNERGWRLTPQRETILHIFQELPQGEHLSAEDLYHRLEADGEGISLST
EEECCCCEEEEECCCCCEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHH
IYRTLKLMARMGILRELELGEGHKHYEINQPYPHHHHHLICVKCNSTIEFKNDSILKIGA
HHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEEEEECCEEEECCCCEEEECC
KTAQKEGFHLLDCQMTIHAVCPKCQRALMPL
CHHCCCCCEEEEHHHHHHHHCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8704986 [H]