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The map label for this gene is rpoC1 [H]

Identifier: 17229087

GI number: 17229087

Start: 1870588

End: 1872465

Strand: Direct

Name: rpoC1 [H]

Synonym: alr1595

Alternate gene names: 17229087

Gene position: 1870588-1872465 (Clockwise)

Preceding gene: 17229086

Following gene: 17229088

Centisome position: 29.17

GC content: 46.59

Gene sequence:

>1878_bases
ATGAGACCCGCCCAAACTAATCAGTTTGACTACGTTAAAATCGGCTTGGCATCACCAGAACGTATTCGCCAATGGGGTGA
GCGTACATTACCTAATGGTCAGGTCGTAGGTGAAGTCACCAAACCAGAAACGATTAATTACCGGACTCTCAAGCCTGAAA
TGGATGGCTTATTTTGTGAGCGCATTTTTGGCCCCGCGAAAGATTGGGAATGCCATTGCGGTAAGTATAAGAGAGTCCGC
CATAGAGGCATTGTCTGTGAGCGTTGTGGCGTGGAAGTTACCGAGTCACGGGTACGCCGTCACCGCATGGGGTACATTAA
ACTCGCTGCCCCAGTAGCCCACGTTTGGTATCTCAAAGGGATTCCTAGCTATATTTCTATTCTGCTAGATATGCCTTTGC
GGGATGTGGAGCAGATTGTCTATTTCAACTCTTATGTTGTTCTCAGTCCCGGTAATGCCGAAACCCTAACCTACAAGCAG
CTACTGAGTGAAGATCAATGGTTAGAAATTGAAGACCAAATCTATAGTGAAGATTCTCAATTGCAAGGTGTAGAGGTAGG
TATCGGTGCTGAAGCACTGTTGCGCTTGCTGGCTGATATTAATTTAGAGCAAGAAGCGGAAAGTCTACGGGAAGAAATTG
GCAGTGCTAAAGGACAAAAACGAGCAAAACTTATTAAGCGCCTGCGGGTAATTGATAACTTCATCGCTACCGGTTCTAAG
CCAGAGTGGATGGTGATGACAGTGATTCCTGTAATCCCTCCAGATTTGCGCCCAATGGTGCAGTTAGATGGTGGACGGTT
TGCTACCAGTGACTTGAATGATTTATATCGTCGGGTAATTAACCGGAATAATCGTTTGGCACGACTGCAAGAGATTCTTG
CACCGGAAATTATCGTGCGGAACGAAAAGCGGATGCTGCAAGAAGCAGTAGACGCTTTGATTGACAACGGTCGTCGGGGA
CGTACTGTGGTTGGGGCAAACAACCGACCCCTAAAATCTTTATCAGACATTATTGAAGGTAAGCAAGGACGTTTCCGGCA
AAACTTGTTAGGTAAACGGGTTGACTACTCTGGACGTTCTGTAATTGTGGTCGGGCCAAAGCTGAAAATTCACCAGTGCG
GCTTGCCCAGAGAAATGGCAATTGAACTATTCCAGCCATTTGTCATTAATCGTCTGATTCGCAGTGGCATGGTGAATAAC
ATCAAAGCTGCGAAAAAGTTAATCTCTCGCAATGACCCCAGTGTTTGGGATGTCCTGGAAGAAGTGATTGAAGGACACCC
AGTCATGCTTAACCGTGCGCCTACCCTACACCGTTTGGGTATTCAGGCTTTTGAACCAATTTTGGTGGAAGGTCGAGCCA
TTCAACTCCACCCCTTGGTGTGTCCTGCATTTAACGCTGACTTTGACGGCGACCAAATGGCAGTACACGTCCCCCTATCC
TTGGAAAGCCAGGCAGAAGCAAGGTTGTTAATGCTTGCTTCCAACAATATCCTCTCACCAGCTACAGGTAGACCAATTAT
CACACCTAGCCAAGACATGGTATTGGGGGCTTATTACCTAACTGCGGAAAACCCAGGTGCTACCAAAGGTGCGGGTAAGT
ATTTTGCTTCTCTGGATGACGTGATTATGGCCTTCCAGCAAGAGCAAATTGACTTACACGCTTATGTCTACGTGCGGTTT
GATGGTGATGTAGAATCTGACCAACCAGATACAGAACCTGTGAAGGTGACAACTAACGAAGATGGTAGCCGGACTGTACT
ATATAAGTACCGCCGAGTCAGGGAAGACGCTCAGGGAAATGTAATTTCTCAGTATATATACACCACTCCAGGTCGCGTTA
TTTACAATAAAGCGATTCAAGAAGCACTTGCCAGTTAG

Upstream 100 bases:

>100_bases
CTGCCGAGTGCTGAGGATAAAAACTCAGTACTCATACCTGACAAATTTCTTGATTCATAACTTTTAACTGAATACTTTAC
TCAGAACTCAGCACTTAAGT

Downstream 100 bases:

>100_bases
TTAAGAGTCCAAAGTGAATAGTCCATAGTTAATCGCAATAACTAGGGACTATTCACTAATGGCTAATGACTAATGACCAA
CGACAAAGGACTAATGACTA

Product: DNA-directed RNA polymerase subunit gamma

Products: NA

Alternate protein names: RNAP subunit gamma; RNA polymerase subunit gamma; Transcriptase subunit gamma [H]

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MRPAQTNQFDYVKIGLASPERIRQWGERTLPNGQVVGEVTKPETINYRTLKPEMDGLFCERIFGPAKDWECHCGKYKRVR
HRGIVCERCGVEVTESRVRRHRMGYIKLAAPVAHVWYLKGIPSYISILLDMPLRDVEQIVYFNSYVVLSPGNAETLTYKQ
LLSEDQWLEIEDQIYSEDSQLQGVEVGIGAEALLRLLADINLEQEAESLREEIGSAKGQKRAKLIKRLRVIDNFIATGSK
PEWMVMTVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNGRRG
RTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKIHQCGLPREMAIELFQPFVINRLIRSGMVNN
IKAAKKLISRNDPSVWDVLEEVIEGHPVMLNRAPTLHRLGIQAFEPILVEGRAIQLHPLVCPAFNADFDGDQMAVHVPLS
LESQAEARLLMLASNNILSPATGRPIITPSQDMVLGAYYLTAENPGATKGAGKYFASLDDVIMAFQQEQIDLHAYVYVRF
DGDVESDQPDTEPVKVTTNEDGSRTVLYKYRRVREDAQGNVISQYIYTTPGRVIYNKAIQEALAS

Sequences:

>Translated_625_residues
MRPAQTNQFDYVKIGLASPERIRQWGERTLPNGQVVGEVTKPETINYRTLKPEMDGLFCERIFGPAKDWECHCGKYKRVR
HRGIVCERCGVEVTESRVRRHRMGYIKLAAPVAHVWYLKGIPSYISILLDMPLRDVEQIVYFNSYVVLSPGNAETLTYKQ
LLSEDQWLEIEDQIYSEDSQLQGVEVGIGAEALLRLLADINLEQEAESLREEIGSAKGQKRAKLIKRLRVIDNFIATGSK
PEWMVMTVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNGRRG
RTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKIHQCGLPREMAIELFQPFVINRLIRSGMVNN
IKAAKKLISRNDPSVWDVLEEVIEGHPVMLNRAPTLHRLGIQAFEPILVEGRAIQLHPLVCPAFNADFDGDQMAVHVPLS
LESQAEARLLMLASNNILSPATGRPIITPSQDMVLGAYYLTAENPGATKGAGKYFASLDDVIMAFQQEQIDLHAYVYVRF
DGDVESDQPDTEPVKVTTNEDGSRTVLYKYRRVREDAQGNVISQYIYTTPGRVIYNKAIQEALAS
>Mature_625_residues
MRPAQTNQFDYVKIGLASPERIRQWGERTLPNGQVVGEVTKPETINYRTLKPEMDGLFCERIFGPAKDWECHCGKYKRVR
HRGIVCERCGVEVTESRVRRHRMGYIKLAAPVAHVWYLKGIPSYISILLDMPLRDVEQIVYFNSYVVLSPGNAETLTYKQ
LLSEDQWLEIEDQIYSEDSQLQGVEVGIGAEALLRLLADINLEQEAESLREEIGSAKGQKRAKLIKRLRVIDNFIATGSK
PEWMVMTVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNGRRG
RTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKIHQCGLPREMAIELFQPFVINRLIRSGMVNN
IKAAKKLISRNDPSVWDVLEEVIEGHPVMLNRAPTLHRLGIQAFEPILVEGRAIQLHPLVCPAFNADFDGDQMAVHVPLS
LESQAEARLLMLASNNILSPATGRPIITPSQDMVLGAYYLTAENPGATKGAGKYFASLDDVIMAFQQEQIDLHAYVYVRF
DGDVESDQPDTEPVKVTTNEDGSRTVLYKYRRVREDAQGNVISQYIYTTPGRVIYNKAIQEALAS

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=308, Percent_Identity=33.1168831168831, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI39725938, Length=333, Percent_Identity=30.03003003003, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI103471997, Length=224, Percent_Identity=33.4821428571429, Blast_Score=102, Evalue=2e-21,
Organism=Escherichia coli, GI2367335, Length=557, Percent_Identity=61.7594254937163, Blast_Score=736, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=305, Percent_Identity=32.1311475409836, Blast_Score=151, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI25145495, Length=494, Percent_Identity=27.5303643724696, Blast_Score=148, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71998295, Length=342, Percent_Identity=24.2690058479532, Blast_Score=92, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6320061, Length=560, Percent_Identity=26.4285714285714, Blast_Score=146, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6324690, Length=230, Percent_Identity=36.9565217391304, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6324917, Length=298, Percent_Identity=25.503355704698, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17530899, Length=569, Percent_Identity=26.713532513181, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI281360912, Length=529, Percent_Identity=25.5198487712665, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI17647875, Length=362, Percent_Identity=27.3480662983425, Blast_Score=108, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR012755 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 70564; Mature: 70564

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAQTNQFDYVKIGLASPERIRQWGERTLPNGQVVGEVTKPETINYRTLKPEMDGLFCE
CCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCHHHHHHH
RIFGPAKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVAHVWYLKG
HHCCCCCCCCCCCCHHHHHHHCCCEEHHCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHC
IPSYISILLDMPLRDVEQIVYFNSYVVLSPGNAETLTYKQLLSEDQWLEIEDQIYSEDSQ
HHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCEEHHHHHHCCCCC
LQGVEVGIGAEALLRLLADINLEQEAESLREEIGSAKGQKRAKLIKRLRVIDNFIATGSK
CCCEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
PEWMVMTVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVR
CCEEEEEEEECCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCCHHEEC
NEKRMLQEAVDALIDNGRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRS
CHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCE
VIVVGPKLKIHQCGLPREMAIELFQPFVINRLIRSGMVNNIKAAKKLISRNDPSVWDVLE
EEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHH
EVIEGHPVMLNRAPTLHRLGIQAFEPILVEGRAIQLHPLVCPAFNADFDGDQMAVHVPLS
HHHCCCCEEEECCCCHHHHCHHHHCCEEECCCEEEEEEEECCCCCCCCCCCCEEEEEECC
LESQAEARLLMLASNNILSPATGRPIITPSQDMVLGAYYLTAENPGATKGAGKYFASLDD
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHH
VIMAFQQEQIDLHAYVYVRFDGDVESDQPDTEPVKVTTNEDGSRTVLYKYRRVREDAQGN
HHHHHHHCCEEEEEEEEEEECCCCCCCCCCCCCEEEEECCCCCEEHHHHHHHHHHCCCCC
VISQYIYTTPGRVIYNKAIQEALAS
EEEHHEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRPAQTNQFDYVKIGLASPERIRQWGERTLPNGQVVGEVTKPETINYRTLKPEMDGLFCE
CCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCHHHHHHH
RIFGPAKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVAHVWYLKG
HHCCCCCCCCCCCCHHHHHHHCCCEEHHCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHC
IPSYISILLDMPLRDVEQIVYFNSYVVLSPGNAETLTYKQLLSEDQWLEIEDQIYSEDSQ
HHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCEEHHHHHHCCCCC
LQGVEVGIGAEALLRLLADINLEQEAESLREEIGSAKGQKRAKLIKRLRVIDNFIATGSK
CCCEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
PEWMVMTVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVR
CCEEEEEEEECCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCCHHEEC
NEKRMLQEAVDALIDNGRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRS
CHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCE
VIVVGPKLKIHQCGLPREMAIELFQPFVINRLIRSGMVNNIKAAKKLISRNDPSVWDVLE
EEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHH
EVIEGHPVMLNRAPTLHRLGIQAFEPILVEGRAIQLHPLVCPAFNADFDGDQMAVHVPLS
HHHCCCCEEEECCCCHHHHCHHHHCCEEECCCEEEEEEEECCCCCCCCCCCCEEEEEECC
LESQAEARLLMLASNNILSPATGRPIITPSQDMVLGAYYLTAENPGATKGAGKYFASLDD
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHH
VIMAFQQEQIDLHAYVYVRFDGDVESDQPDTEPVKVTTNEDGSRTVLYKYRRVREDAQGN
HHHHHHHCCEEEEEEEEEEECCCCCCCCCCCCCEEEEECCCCCEEHHHHHHHHHHCCCCC
VISQYIYTTPGRVIYNKAIQEALAS
EEEHHEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA