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The map label for this gene is appC [H]

Identifier: 17229048

GI number: 17229048

Start: 1821309

End: 1822427

Strand: Direct

Name: appC [H]

Synonym: alr1556

Alternate gene names: 17229048

Gene position: 1821309-1822427 (Clockwise)

Preceding gene: 17229047

Following gene: 17229050

Centisome position: 28.4

GC content: 44.5

Gene sequence:

>1119_bases
ATGAATTGGTGGCAAAGACTCCAGAAAAATCCCTTAGCACAATTTGGGGCTATTTTACTTTTAATATTTTATTTGGCGGT
GATTGCGGCTGATTTTATCGCTCCATACGACCCTTACACTTCTCAACCGAATGGTTCACTATTACCGCCAACTAAGATTT
ATTGGGTTTCAAAAACATCAGGTAAGTTTATCGGCCCCCACGTTTATCCCACAATACAAGGCAATACAGACTTAGAAACA
GGCGATCGCCAACTCATTGTAGACGATAAAAAGCCCTCACCTGTGCGTTTATTTGTCTCTGGGCCAGAATACCGACTCTT
ACAGCTAAGTTTACCCCTACCGCCCAAGTGGGAAGAAACCACAATTATCCCCGGTATCCCCTTAAATTGGCATTTATTCG
GCGCAGATAATGGGGCAAAACTCAACATCTTAGGTACGGACGAACAAGGCCGCGACCAATTCAGCCGTCTCCTACATGGT
GGGCGCATTAGTATGTTTATCGGCATTATTGGGGTGGTAATTACTTTTCCCCTCGGTTTGCTGATAGGGGGTATTTCCGG
CTATTTCGGCGGTTGGACGGACAGCATTATTATGCGGATTGCAGAAGTGCTGATGACTTTCCCCAGTATTTATCTGTTGG
TTACCTTGGGGGCAGTTTTACCGGCTGGTTTAACTAGCAGTCAGCGATTTTTACTCATAGTTTTGATCACTTCTGTAATT
AGCTGGGCTGGGTTAGCCAGGGTAATTCGTGGACAAGTGCTATCAATCAAAGAACGAGAATTTGTCCAAGCCGCCAGGGC
TATGGGTGGTAAGCCAATATATATTATTCTGCGTCATGTTCTGCCGCAAACTGCTACTTATGTAATTATCTCTGCTACCT
TGGCGGTTCCTAGCTTTATCGGTTCAGAAGCAATACTCAGTCTCATCGGTTTAGGCATTCAACAACCAGACCCATCTTGG
GGTAATATGCTATCTCTAGCCAGCAATGCTTCTATATTAGTGCTGCAACCTTGGTTAATTTGGCCGCCGGCTGTGTTAAT
TATTTTGACAGTTTTAGCTTTTAATTTACTAGGTGATGGGTTAAGAGATGCCCTTGATCCTCGGAGTTTACGCCGCTAG

Upstream 100 bases:

>100_bases
TACCTAGTTGAACAACTCCATGCTTAGATGATAGTCATTGGTCATTGGTCATTGATAACAGACCACTGACCACTGACACC
AGACAAAAGGCAAACAAATT

Downstream 100 bases:

>100_bases
AACCCCAAGGCTTTACCCAGGTTATTGTCCTGGGTAAAAGGCGATCGCAGATTTATTTGATAACAATCTAGCTTTTTTAA
CTCCTGGTTTCGATGTCATA

Product: permease protein of ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MNWWQRLQKNPLAQFGAILLLIFYLAVIAADFIAPYDPYTSQPNGSLLPPTKIYWVSKTSGKFIGPHVYPTIQGNTDLET
GDRQLIVDDKKPSPVRLFVSGPEYRLLQLSLPLPPKWEETTIIPGIPLNWHLFGADNGAKLNILGTDEQGRDQFSRLLHG
GRISMFIGIIGVVITFPLGLLIGGISGYFGGWTDSIIMRIAEVLMTFPSIYLLVTLGAVLPAGLTSSQRFLLIVLITSVI
SWAGLARVIRGQVLSIKEREFVQAARAMGGKPIYIILRHVLPQTATYVIISATLAVPSFIGSEAILSLIGLGIQQPDPSW
GNMLSLASNASILVLQPWLIWPPAVLIILTVLAFNLLGDGLRDALDPRSLRR

Sequences:

>Translated_372_residues
MNWWQRLQKNPLAQFGAILLLIFYLAVIAADFIAPYDPYTSQPNGSLLPPTKIYWVSKTSGKFIGPHVYPTIQGNTDLET
GDRQLIVDDKKPSPVRLFVSGPEYRLLQLSLPLPPKWEETTIIPGIPLNWHLFGADNGAKLNILGTDEQGRDQFSRLLHG
GRISMFIGIIGVVITFPLGLLIGGISGYFGGWTDSIIMRIAEVLMTFPSIYLLVTLGAVLPAGLTSSQRFLLIVLITSVI
SWAGLARVIRGQVLSIKEREFVQAARAMGGKPIYIILRHVLPQTATYVIISATLAVPSFIGSEAILSLIGLGIQQPDPSW
GNMLSLASNASILVLQPWLIWPPAVLIILTVLAFNLLGDGLRDALDPRSLRR
>Mature_372_residues
MNWWQRLQKNPLAQFGAILLLIFYLAVIAADFIAPYDPYTSQPNGSLLPPTKIYWVSKTSGKFIGPHVYPTIQGNTDLET
GDRQLIVDDKKPSPVRLFVSGPEYRLLQLSLPLPPKWEETTIIPGIPLNWHLFGADNGAKLNILGTDEQGRDQFSRLLHG
GRISMFIGIIGVVITFPLGLLIGGISGYFGGWTDSIIMRIAEVLMTFPSIYLLVTLGAVLPAGLTSSQRFLLIVLITSVI
SWAGLARVIRGQVLSIKEREFVQAARAMGGKPIYIILRHVLPQTATYVIISATLAVPSFIGSEAILSLIGLGIQQPDPSW
GNMLSLASNASILVLQPWLIWPPAVLIILTVLAFNLLGDGLRDALDPRSLRR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=234, Percent_Identity=41.8803418803419, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI1787498, Length=227, Percent_Identity=40.5286343612335, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1787760, Length=226, Percent_Identity=38.4955752212389, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1789889, Length=225, Percent_Identity=35.5555555555556, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1789964, Length=259, Percent_Identity=34.7490347490347, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788505, Length=233, Percent_Identity=30.9012875536481, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787549, Length=240, Percent_Identity=29.1666666666667, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 40779; Mature: 40779

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWWQRLQKNPLAQFGAILLLIFYLAVIAADFIAPYDPYTSQPNGSLLPPTKIYWVSKTS
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCC
GKFIGPHVYPTIQGNTDLETGDRQLIVDDKKPSPVRLFVSGPEYRLLQLSLPLPPKWEET
CCEECCCCCEEECCCCCCCCCCCEEEEECCCCCCEEEEECCCCEEEEEEECCCCCCCCCC
TIIPGIPLNWHLFGADNGAKLNILGTDEQGRDQFSRLLHGGRISMFIGIIGVVITFPLGL
EECCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LIGGISGYFGGWTDSIIMRIAEVLMTFPSIYLLVTLGAVLPAGLTSSQRFLLIVLITSVI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
SWAGLARVIRGQVLSIKEREFVQAARAMGGKPIYIILRHVLPQTATYVIISATLAVPSFI
HHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHEEEEEHHHHHHHHH
GSEAILSLIGLGIQQPDPSWGNMLSLASNASILVLQPWLIWPPAVLIILTVLAFNLLGDG
HHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEEEEECHHHCHHHHHHHHHHHHHHHHHHH
LRDALDPRSLRR
HHHHCCHHHHCC
>Mature Secondary Structure
MNWWQRLQKNPLAQFGAILLLIFYLAVIAADFIAPYDPYTSQPNGSLLPPTKIYWVSKTS
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCC
GKFIGPHVYPTIQGNTDLETGDRQLIVDDKKPSPVRLFVSGPEYRLLQLSLPLPPKWEET
CCEECCCCCEEECCCCCCCCCCCEEEEECCCCCCEEEEECCCCEEEEEEECCCCCCCCCC
TIIPGIPLNWHLFGADNGAKLNILGTDEQGRDQFSRLLHGGRISMFIGIIGVVITFPLGL
EECCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LIGGISGYFGGWTDSIIMRIAEVLMTFPSIYLLVTLGAVLPAGLTSSQRFLLIVLITSVI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
SWAGLARVIRGQVLSIKEREFVQAARAMGGKPIYIILRHVLPQTATYVIISATLAVPSFI
HHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHEEEEEHHHHHHHHH
GSEAILSLIGLGIQQPDPSWGNMLSLASNASILVLQPWLIWPPAVLIILTVLAFNLLGDG
HHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEEEEECHHHCHHHHHHHHHHHHHHHHHHH
LRDALDPRSLRR
HHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]