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The map label for this gene is atoS [H]

Identifier: 17229043

GI number: 17229043

Start: 1811833

End: 1813647

Strand: Direct

Name: atoS [H]

Synonym: alr1551

Alternate gene names: 17229043

Gene position: 1811833-1813647 (Clockwise)

Preceding gene: 17229042

Following gene: 17229044

Centisome position: 28.25

GC content: 37.58

Gene sequence:

>1815_bases
ATGCTGACTATCAAGTTGAGTGTTGGGCAAAGGATTAGTCTAGGATACGCCATTGCCCTGGGGGTTAGTATTTTGGGTAC
AGTAGCAGGTTTCAGCATTGGGAAAAATTATCTACGACAAGCTTCCGAATGGGAAGAACACGCTCGTGAAGAAATGGAAT
TACTACACCACTTGCAAATAGATATTTTGCAAGCGCGGACTCATCAGCAACAACTGATTCCATTAGTAAAATATCCCCAA
CGTTACGCTCAGGAATACAGTTATTTGCTGCACCATAAAGCGGAAATAGAGAATTCCTGGATTGAGATCAGGACTTTCAT
CAAGATGCACCCTGTATCTTCGGGGGATCTCCATGTTACAGAACTACCAAAATTTTTGCACACTTATAATTACGTCCTGC
AACAGTATTTCCAAGAACTAGAACTCCGAAAACAGCAGATTCAGGGGTTGAATTTAAAGATACCAGGAGAGATTGAAAAA
GCTCAGACAATATTACTGGAATTTACTGATAGTGAGCTATCCCTAAAGTTTGATCGCATATCTGATGACGTGGATAAACT
GCTGCAAAAAGCATACGCCGAAACAGAAGAAGCTGAAGAATTTCAGCAAACATCTAGCGGAATAGCTCAAAGAATTGTCA
TTGTTAGCATCATTATATCAGTTACTATTTCGGTTATATTGGCAATTTTTACCAGTCGGGCGATCGCCTCTCCTATTCAA
GCCATAACTAATGTAGCTAGACGCTCTACAGAAGAGTCTAATTTTGATTTACAAGTAACTATTAATCGTGATGATGAACT
GGGTGTGCTTGGCAATTCCTTCAATCAATTAATTGCTACGGTTAAAAAATTACTAACACAACAGCAACAAGCTAACGAAC
AACTGACTAATTACAACGAAACCTTAGAAAACAGGAATCAAGAAATTAGTGAAAAAAATAACCAATTGCAACAAGTACTC
GAAGAACTACAGCGTAGTCAATTGAAAATGGTACAAAGTGAAAAAATGTCTGCTTTGGGTCAAATGGTAGCAGGGATAGC
TCACGAAATCAACAATCCAGTCAGCTTTATTCACGGCAATTTAACGTATGTGCAAGAATATACTGAAAATCTGATCCAGT
TTGTGCAGTTGTATCATAAATACTACCCTGAGCCTTTATCGGAAATAGTTAACTTAGCAGAGCATATCGACCTAGATTTT
ATCCAGGAAGATTTACCAAAAATGCTGAGTTCCATGAAAATAGGAACAGATAGAATTTGTAAACTTGTGCTATCACTGCG
GAATTTTTCGCGTCTTGATGAATCAGAATTCAAAGCAGTGGATATTCACGAAGGTATTGATAATACTCTACTAATTTTAC
AACATCGTCTGAAAGAAAAGCCAGAACATCAGGAAATTAAAGTTGTTAAAAATTATGGTTACTTACCTTTAATAGAATGC
TATCCTGGGCAATTAAATCAAGTATTTATGAATATTTTAGTTAATGCTATTGATGCTCTGGAAGAAAAAACAGATACACA
AAAAACTAGCCAAATAACTATTACTACTTCAGTTAAAGATTCTCGGTGGTTGCAAATTGCGATCGCTGATAATGGTTCCG
GTATCCCCGCAGATATTCAAGCCAAGATTTTCCAGCCGTTCTTTACTACAAAACCATCCGGTAAAGGTACAGGAATGGGA
ATGTCTATCAGTCAGCAGATTATTATCGAAAGACATAGCGGTAAACTAGAATGCTTCTCAACTATTGGTGAGGGAACAGA
GTTTTTGATTCAGATTCCTGTAAGTCAAAACCTCACAGTTTCCCCTGTTAAGTAG

Upstream 100 bases:

>100_bases
CAAATGAAGATTAGATGATGACTGGAGTTGTGGTGTAAGAATAGATAAAAATCATGGGAATCATAGAATCTACGAGATTT
TAGGTAACTGTGTAGATTCT

Downstream 100 bases:

>100_bases
CACCAATTCGCTTGTAAATATGATTTAGCGTCGATAACAAGGTAAGTTAGCATCGGTTACAGAATTTTGATTGTCTTGAA
CAGCTACTTTAGCGGATCTG

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MLTIKLSVGQRISLGYAIALGVSILGTVAGFSIGKNYLRQASEWEEHAREEMELLHHLQIDILQARTHQQQLIPLVKYPQ
RYAQEYSYLLHHKAEIENSWIEIRTFIKMHPVSSGDLHVTELPKFLHTYNYVLQQYFQELELRKQQIQGLNLKIPGEIEK
AQTILLEFTDSELSLKFDRISDDVDKLLQKAYAETEEAEEFQQTSSGIAQRIVIVSIIISVTISVILAIFTSRAIASPIQ
AITNVARRSTEESNFDLQVTINRDDELGVLGNSFNQLIATVKKLLTQQQQANEQLTNYNETLENRNQEISEKNNQLQQVL
EELQRSQLKMVQSEKMSALGQMVAGIAHEINNPVSFIHGNLTYVQEYTENLIQFVQLYHKYYPEPLSEIVNLAEHIDLDF
IQEDLPKMLSSMKIGTDRICKLVLSLRNFSRLDESEFKAVDIHEGIDNTLLILQHRLKEKPEHQEIKVVKNYGYLPLIEC
YPGQLNQVFMNILVNAIDALEEKTDTQKTSQITITTSVKDSRWLQIAIADNGSGIPADIQAKIFQPFFTTKPSGKGTGMG
MSISQQIIIERHSGKLECFSTIGEGTEFLIQIPVSQNLTVSPVK

Sequences:

>Translated_604_residues
MLTIKLSVGQRISLGYAIALGVSILGTVAGFSIGKNYLRQASEWEEHAREEMELLHHLQIDILQARTHQQQLIPLVKYPQ
RYAQEYSYLLHHKAEIENSWIEIRTFIKMHPVSSGDLHVTELPKFLHTYNYVLQQYFQELELRKQQIQGLNLKIPGEIEK
AQTILLEFTDSELSLKFDRISDDVDKLLQKAYAETEEAEEFQQTSSGIAQRIVIVSIIISVTISVILAIFTSRAIASPIQ
AITNVARRSTEESNFDLQVTINRDDELGVLGNSFNQLIATVKKLLTQQQQANEQLTNYNETLENRNQEISEKNNQLQQVL
EELQRSQLKMVQSEKMSALGQMVAGIAHEINNPVSFIHGNLTYVQEYTENLIQFVQLYHKYYPEPLSEIVNLAEHIDLDF
IQEDLPKMLSSMKIGTDRICKLVLSLRNFSRLDESEFKAVDIHEGIDNTLLILQHRLKEKPEHQEIKVVKNYGYLPLIEC
YPGQLNQVFMNILVNAIDALEEKTDTQKTSQITITTSVKDSRWLQIAIADNGSGIPADIQAKIFQPFFTTKPSGKGTGMG
MSISQQIIIERHSGKLECFSTIGEGTEFLIQIPVSQNLTVSPVK
>Mature_604_residues
MLTIKLSVGQRISLGYAIALGVSILGTVAGFSIGKNYLRQASEWEEHAREEMELLHHLQIDILQARTHQQQLIPLVKYPQ
RYAQEYSYLLHHKAEIENSWIEIRTFIKMHPVSSGDLHVTELPKFLHTYNYVLQQYFQELELRKQQIQGLNLKIPGEIEK
AQTILLEFTDSELSLKFDRISDDVDKLLQKAYAETEEAEEFQQTSSGIAQRIVIVSIIISVTISVILAIFTSRAIASPIQ
AITNVARRSTEESNFDLQVTINRDDELGVLGNSFNQLIATVKKLLTQQQQANEQLTNYNETLENRNQEISEKNNQLQQVL
EELQRSQLKMVQSEKMSALGQMVAGIAHEINNPVSFIHGNLTYVQEYTENLIQFVQLYHKYYPEPLSEIVNLAEHIDLDF
IQEDLPKMLSSMKIGTDRICKLVLSLRNFSRLDESEFKAVDIHEGIDNTLLILQHRLKEKPEHQEIKVVKNYGYLPLIEC
YPGQLNQVFMNILVNAIDALEEKTDTQKTSQITITTSVKDSRWLQIAIADNGSGIPADIQAKIFQPFFTTKPSGKGTGMG
MSISQQIIIERHSGKLECFSTIGEGTEFLIQIPVSQNLTVSPVK

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=276, Percent_Identity=30.4347826086957, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1790436, Length=279, Percent_Identity=27.9569892473118, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790300, Length=294, Percent_Identity=26.8707482993197, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68754; Mature: 68754

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS50885 HAMP ; PS00041 HTH_ARAC_FAMILY_1 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTIKLSVGQRISLGYAIALGVSILGTVAGFSIGKNYLRQASEWEEHAREEMELLHHLQI
CEEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DILQARTHQQQLIPLVKYPQRYAQEYSYLLHHKAEIENSWIEIRTFIKMHPVSSGDLHVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCEEHH
ELPKFLHTYNYVLQQYFQELELRKQQIQGLNLKIPGEIEKAQTILLEFTDSELSLKFDRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHEEEEEEECCCCEEEHHHH
SDDVDKLLQKAYAETEEAEEFQQTSSGIAQRIVIVSIIISVTISVILAIFTSRAIASPIQ
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AITNVARRSTEESNFDLQVTINRDDELGVLGNSFNQLIATVKKLLTQQQQANEQLTNYNE
HHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLENRNQEISEKNNQLQQVLEELQRSQLKMVQSEKMSALGQMVAGIAHEINNPVSFIHGN
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
LTYVQEYTENLIQFVQLYHKYYPEPLSEIVNLAEHIDLDFIQEDLPKMLSSMKIGTDRIC
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHH
KLVLSLRNFSRLDESEFKAVDIHEGIDNTLLILQHRLKEKPEHQEIKVVKNYGYLPLIEC
HHHHHHHHHHHCCHHHCCEEEHHCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEC
YPGQLNQVFMNILVNAIDALEEKTDTQKTSQITITTSVKDSRWLQIAIADNGSGIPADIQ
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCHH
AKIFQPFFTTKPSGKGTGMGMSISQQIIIERHSGKLECFSTIGEGTEFLIQIPVSQNLTV
HHHHCHHHCCCCCCCCCCCCCCHHHHHHEECCCCCCHHHHHHCCCCEEEEEECCCCCCEE
SPVK
CCCC
>Mature Secondary Structure
MLTIKLSVGQRISLGYAIALGVSILGTVAGFSIGKNYLRQASEWEEHAREEMELLHHLQI
CEEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DILQARTHQQQLIPLVKYPQRYAQEYSYLLHHKAEIENSWIEIRTFIKMHPVSSGDLHVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCEEHH
ELPKFLHTYNYVLQQYFQELELRKQQIQGLNLKIPGEIEKAQTILLEFTDSELSLKFDRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHEEEEEEECCCCEEEHHHH
SDDVDKLLQKAYAETEEAEEFQQTSSGIAQRIVIVSIIISVTISVILAIFTSRAIASPIQ
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AITNVARRSTEESNFDLQVTINRDDELGVLGNSFNQLIATVKKLLTQQQQANEQLTNYNE
HHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLENRNQEISEKNNQLQQVLEELQRSQLKMVQSEKMSALGQMVAGIAHEINNPVSFIHGN
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
LTYVQEYTENLIQFVQLYHKYYPEPLSEIVNLAEHIDLDFIQEDLPKMLSSMKIGTDRIC
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHH
KLVLSLRNFSRLDESEFKAVDIHEGIDNTLLILQHRLKEKPEHQEIKVVKNYGYLPLIEC
HHHHHHHHHHHCCHHHCCEEEHHCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEC
YPGQLNQVFMNILVNAIDALEEKTDTQKTSQITITTSVKDSRWLQIAIADNGSGIPADIQ
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCHH
AKIFQPFFTTKPSGKGTGMGMSISQQIIIERHSGKLECFSTIGEGTEFLIQIPVSQNLTV
HHHHCHHHCCCCCCCCCCCCCCHHHHHHEECCCCCCHHHHHHCCCCEEEEEECCCCCCEE
SPVK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]