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The map label for this gene is macB [H]

Identifier: 17228999

GI number: 17228999

Start: 1768468

End: 1769763

Strand: Direct

Name: macB [H]

Synonym: alr1506

Alternate gene names: 17228999

Gene position: 1768468-1769763 (Clockwise)

Preceding gene: 17228998

Following gene: 17229000

Centisome position: 27.57

GC content: 47.84

Gene sequence:

>1296_bases
ATGAAAAAACTTACTAATTTACAGACAAAAACTCGTCCGCGCCGTTCGGGAAAGCGTAAGGTATCTTTCAGTGAAGTTTT
GATCATGTCAGTCGAAACACTGTGGGGTAATAAACTGCGGACAGGTTTGACTATGTTGGGGGTGATTATTGGCATCTCCT
CGGTGATTACGATTACCTCTGTGGGACAGGGCGTACAAAAGTCAACAGAGTTACAAATCCAAGCCTTGGGAACAAATGTG
ATGTTGGTTTCCGCAGGGGCAGCCAGAACAGGCGGTATCAGCCAAGGCGCAGGTTCAGCCAGTACACTAACCTGGGAAGA
TGCCCAGGCGATCGCCAAACAAGTCCCAGCCGCTAAATCGGTTTCGGCATTCTTACAACGTGGTTCAATTCAGGTCGTCA
GGGGCAATACCAACATCGCCACGACCCTTTTAGGCACGGATTTGAACTATCCAACGATGAAAAATATTCATCCCCAAGTG
GGACTATTTTTTAATCAAGGGGATTTAGATGCTGGGCGACCTGTGGCGTTTCTCGGTTCTAAGGTGCGAGATGAATTATT
CAACGCAGACGAAACTGTGATTGGAACTGATTTGCGGATTCGGGGCAAACGATACACTGTCGTTGGGGTGGCGGAATCAA
AAGGAACGTCGGGTGGACAGGATCTAGACGATCTGATTTATATCCCCCTTACCAATATGTCTGCCCAAATTGTGGGCAAT
AACGCCTTGACGGGTGTAGCAATTAATGGATTCTGGGTAGAAGCAAGCGATGGCGATCAACTGAACTCGGCTCAATTTCA
GGTGACAAATATTCTGCGTCTACGGCATGGCATTCATCCGTCAGATGTCGATGATTTTCGGATTATCAATTTAGTTGATA
TTATCAGCACTTTCAGCAATGTGATGGGGTCATTTACCTTGATGATCGGTGCGATCGCCGGGATTTCCCTAGTTGTGGGC
GGTATTGGCATTGCCAACATCATGCTAGTTTCAGTGATGGAACGAACGCGAGAAATCGGCATTCGTAAAGCTGTGGGCGC
AACCGGCACAGATATTTTGAGCCAGTTTTTGACGGAGGCGATCGTTATCTCCACGGTTGGCGGTGTGATTGGTGTGGGAT
TGGGTATCGGGTTCGCCTTTGCTGCCGCAACTGTGTTCAAATTTCCGTTTATTGTGCCGTTGTGGTCGATTGGGACAGGA
TTTAGCCTTTCATTAGTAGTTGGCGTTCTGGCTGGCGGTATCCCAGCGCGGAATGCTGCCAAATTAGATCCAATTTCAGC
ACTACACAATGAGTGA

Upstream 100 bases:

>100_bases
ACAAAACCGAGGTCAAATCTGGCTTAACTGGAAACGAAAACGTTTTACTCAGCTTTCCACCTGGAACTCGTAAGGTTTCT
ACAGCTAATGGCAGACCTTC

Downstream 100 bases:

>100_bases
TCGCTATGGCAACTATGATCTCGATGGAAGGCATTACCAAAACCTATCACTTAGGAGAATTGGATGTACCCGTTCTCAAG
GAAATTAATTTATCAATTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MKKLTNLQTKTRPRRSGKRKVSFSEVLIMSVETLWGNKLRTGLTMLGVIIGISSVITITSVGQGVQKSTELQIQALGTNV
MLVSAGAARTGGISQGAGSASTLTWEDAQAIAKQVPAAKSVSAFLQRGSIQVVRGNTNIATTLLGTDLNYPTMKNIHPQV
GLFFNQGDLDAGRPVAFLGSKVRDELFNADETVIGTDLRIRGKRYTVVGVAESKGTSGGQDLDDLIYIPLTNMSAQIVGN
NALTGVAINGFWVEASDGDQLNSAQFQVTNILRLRHGIHPSDVDDFRIINLVDIISTFSNVMGSFTLMIGAIAGISLVVG
GIGIANIMLVSVMERTREIGIRKAVGATGTDILSQFLTEAIVISTVGGVIGVGLGIGFAFAAATVFKFPFIVPLWSIGTG
FSLSLVVGVLAGGIPARNAAKLDPISALHNE

Sequences:

>Translated_431_residues
MKKLTNLQTKTRPRRSGKRKVSFSEVLIMSVETLWGNKLRTGLTMLGVIIGISSVITITSVGQGVQKSTELQIQALGTNV
MLVSAGAARTGGISQGAGSASTLTWEDAQAIAKQVPAAKSVSAFLQRGSIQVVRGNTNIATTLLGTDLNYPTMKNIHPQV
GLFFNQGDLDAGRPVAFLGSKVRDELFNADETVIGTDLRIRGKRYTVVGVAESKGTSGGQDLDDLIYIPLTNMSAQIVGN
NALTGVAINGFWVEASDGDQLNSAQFQVTNILRLRHGIHPSDVDDFRIINLVDIISTFSNVMGSFTLMIGAIAGISLVVG
GIGIANIMLVSVMERTREIGIRKAVGATGTDILSQFLTEAIVISTVGGVIGVGLGIGFAFAAATVFKFPFIVPLWSIGTG
FSLSLVVGVLAGGIPARNAAKLDPISALHNE
>Mature_431_residues
MKKLTNLQTKTRPRRSGKRKVSFSEVLIMSVETLWGNKLRTGLTMLGVIIGISSVITITSVGQGVQKSTELQIQALGTNV
MLVSAGAARTGGISQGAGSASTLTWEDAQAIAKQVPAAKSVSAFLQRGSIQVVRGNTNIATTLLGTDLNYPTMKNIHPQV
GLFFNQGDLDAGRPVAFLGSKVRDELFNADETVIGTDLRIRGKRYTVVGVAESKGTSGGQDLDDLIYIPLTNMSAQIVGN
NALTGVAINGFWVEASDGDQLNSAQFQVTNILRLRHGIHPSDVDDFRIINLVDIISTFSNVMGSFTLMIGAIAGISLVVG
GIGIANIMLVSVMERTREIGIRKAVGATGTDILSQFLTEAIVISTVGGVIGVGLGIGFAFAAATVFKFPFIVPLWSIGTG
FSLSLVVGVLAGGIPARNAAKLDPISALHNE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=416, Percent_Identity=36.0576923076923, Blast_Score=205, Evalue=6e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45296; Mature: 45296

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: PS00053 RIBOSOMAL_S8

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLTNLQTKTRPRRSGKRKVSFSEVLIMSVETLWGNKLRTGLTMLGVIIGISSVITITS
CCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
VGQGVQKSTELQIQALGTNVMLVSAGAARTGGISQGAGSASTLTWEDAQAIAKQVPAAKS
HCCCCCCCCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCHHH
VSAFLQRGSIQVVRGNTNIATTLLGTDLNYPTMKNIHPQVGLFFNQGDLDAGRPVAFLGS
HHHHHHCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHH
KVRDELFNADETVIGTDLRIRGKRYTVVGVAESKGTSGGQDLDDLIYIPLTNMSAQIVGN
HHHHHHHCCCCEEECCCEEECCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCEEEEECC
NALTGVAINGFWVEASDGDQLNSAQFQVTNILRLRHGIHPSDVDDFRIINLVDIISTFSN
CCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
VMGSFTLMIGAIAGISLVVGGIGIANIMLVSVMERTREIGIRKAVGATGTDILSQFLTEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHH
IVISTVGGVIGVGLGIGFAFAAATVFKFPFIVPLWSIGTGFSLSLVVGVLAGGIPARNAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC
KLDPISALHNE
CCCCHHHHCCC
>Mature Secondary Structure
MKKLTNLQTKTRPRRSGKRKVSFSEVLIMSVETLWGNKLRTGLTMLGVIIGISSVITITS
CCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
VGQGVQKSTELQIQALGTNVMLVSAGAARTGGISQGAGSASTLTWEDAQAIAKQVPAAKS
HCCCCCCCCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCHHH
VSAFLQRGSIQVVRGNTNIATTLLGTDLNYPTMKNIHPQVGLFFNQGDLDAGRPVAFLGS
HHHHHHCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHH
KVRDELFNADETVIGTDLRIRGKRYTVVGVAESKGTSGGQDLDDLIYIPLTNMSAQIVGN
HHHHHHHCCCCEEECCCEEECCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCEEEEECC
NALTGVAINGFWVEASDGDQLNSAQFQVTNILRLRHGIHPSDVDDFRIINLVDIISTFSN
CCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
VMGSFTLMIGAIAGISLVVGGIGIANIMLVSVMERTREIGIRKAVGATGTDILSQFLTEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHH
IVISTVGGVIGVGLGIGFAFAAATVFKFPFIVPLWSIGTGFSLSLVVGVLAGGIPARNAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC
KLDPISALHNE
CCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA