Click here to switch to the map view.

The map label for this gene is rsmB [H]

Identifier: 17228315

GI number: 17228315

Start: 944828

End: 946177

Strand: Direct

Name: rsmB [H]

Synonym: alr0820

Alternate gene names: 17228315

Gene position: 944828-946177 (Clockwise)

Preceding gene: 17228314

Following gene: 17228316

Centisome position: 14.73

GC content: 44.37

Gene sequence:

>1350_bases
ATGACAAATTCCCGTCAAATAGCTTTTATCGCCTTGAGAGATGTGCATAAAGGGGCTTATACAGATGTTGCTTTAGATAG
AGCATTGCAAAAAGCAAATTTATCAGATATTGACCGCCGGTTGGTGACAGAATTACTTTATGGCAGTGTGAGAAGACAAC
GGACTCTTGATTTTATTATTGACCAACTCGCCAAAAAGAAATCACACCAACAGCCAACAGAACTCCGCAGTATCTTACAT
TTAGGTTTATATCAACTGCGTTATCAAGAGCGTATCCCTGCTTCTGCGGCTGTGAATACTACTGTGGAATTAGCGAAAGA
TAATGGTTTTGCTGGGTTGACAGGTTTTGTTAATGGTTTATTACGGCAATATATCCGGTTGGCTGAAGCATCACCAGACT
TTCTCGAACTCCCAGAAAATCCGGTGGAAAGGTTGGGAATTTTACATAGCTTTCCTGACTGGATTATTAAAGTATGGTGG
GAACAGTTGGGTTTGACGGAGACAGAAAAACTCTGTGAATGGATGAATCAAACACCAACCCTTGATTTGAGAGTCAACCC
CTTACTTGCTTCCGTTGCAGAAGTGGAAACAGCTTTAAAATCGGCTGGGGTTTTGGCTAGACCTATTCCTCATTTACCCC
AAGCTTTACGACTCATTGGCAATAATGGTTCTATCCAAAAGCTTCCAGGGTTTAGCCAAGGTTGGTGGATTGTACAGGAT
GCTAGCGCTCAGTTAGTTGGTCATTTGCTTGATCCCCAACCTGGTGAAGTGATCATTGATGCTTGTGCTGCACCGGGGGG
GAAGACGACTCACATTGCTGAGTTAATGAAAGATGAGGGAAAAGTTTGGGCAGGCGATCGCACTGCTTCACGTTTGCGTA
AACTGAAAGAGAATGCCCAACGCCTGAATTTACACTCGATTGAGATTTGCATCGGTGACAGTCGCAACTTACCACAATTT
TATGATGTTGCTGACCGTGTTTTACTGGATGCCCCATGTTCTGGCTTGGGGACTTTGCACCGCCATGCTGATGCGCGCTG
GCGACAAACACCAGAATCTGTCCAAGAACTCTCGATGCTGCAAAAGGAACTATTAGCACATACATCAAAATTTGTCAAAG
TTGGGGGTGTGCTGGTTTATGCCACTTGCACGTTACATCCAGCAGAAAATGAAGAAGTAATTACGGAATTTGTGGCGGGG
AATTCTGATTGGCAAATTGAGCCGCCTAGACCCGATTCGCCTTATTCTGCCTACACTACACCACAAGGCTGGCTGAAAGT
TTGGCCTCACAATCAAGATATGGACGGCTTTTTCATGGTGCGCTTAAGAAAAACCAACGTTTCCGAATGA

Upstream 100 bases:

>100_bases
TAAAATTTTATTGCGTAACCCCTTGTAATTGCCAGGGGTTTTTTATTTTTCATCTCCCAGAATGTTGGGATAGGGCAAAT
TCTATACTCGAAAATTTTCC

Downstream 100 bases:

>100_bases
TTACTATCAGGGATAGTACGATTTGATTGAAGCCTGAATCTCCCAGAGGAGGCAGCGATGGTGACAGATTCCAATGTAAA
AAATTTAGTTAAAATCTTGA

Product: sun protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MTNSRQIAFIALRDVHKGAYTDVALDRALQKANLSDIDRRLVTELLYGSVRRQRTLDFIIDQLAKKKSHQQPTELRSILH
LGLYQLRYQERIPASAAVNTTVELAKDNGFAGLTGFVNGLLRQYIRLAEASPDFLELPENPVERLGILHSFPDWIIKVWW
EQLGLTETEKLCEWMNQTPTLDLRVNPLLASVAEVETALKSAGVLARPIPHLPQALRLIGNNGSIQKLPGFSQGWWIVQD
ASAQLVGHLLDPQPGEVIIDACAAPGGKTTHIAELMKDEGKVWAGDRTASRLRKLKENAQRLNLHSIEICIGDSRNLPQF
YDVADRVLLDAPCSGLGTLHRHADARWRQTPESVQELSMLQKELLAHTSKFVKVGGVLVYATCTLHPAENEEVITEFVAG
NSDWQIEPPRPDSPYSAYTTPQGWLKVWPHNQDMDGFFMVRLRKTNVSE

Sequences:

>Translated_449_residues
MTNSRQIAFIALRDVHKGAYTDVALDRALQKANLSDIDRRLVTELLYGSVRRQRTLDFIIDQLAKKKSHQQPTELRSILH
LGLYQLRYQERIPASAAVNTTVELAKDNGFAGLTGFVNGLLRQYIRLAEASPDFLELPENPVERLGILHSFPDWIIKVWW
EQLGLTETEKLCEWMNQTPTLDLRVNPLLASVAEVETALKSAGVLARPIPHLPQALRLIGNNGSIQKLPGFSQGWWIVQD
ASAQLVGHLLDPQPGEVIIDACAAPGGKTTHIAELMKDEGKVWAGDRTASRLRKLKENAQRLNLHSIEICIGDSRNLPQF
YDVADRVLLDAPCSGLGTLHRHADARWRQTPESVQELSMLQKELLAHTSKFVKVGGVLVYATCTLHPAENEEVITEFVAG
NSDWQIEPPRPDSPYSAYTTPQGWLKVWPHNQDMDGFFMVRLRKTNVSE
>Mature_448_residues
TNSRQIAFIALRDVHKGAYTDVALDRALQKANLSDIDRRLVTELLYGSVRRQRTLDFIIDQLAKKKSHQQPTELRSILHL
GLYQLRYQERIPASAAVNTTVELAKDNGFAGLTGFVNGLLRQYIRLAEASPDFLELPENPVERLGILHSFPDWIIKVWWE
QLGLTETEKLCEWMNQTPTLDLRVNPLLASVAEVETALKSAGVLARPIPHLPQALRLIGNNGSIQKLPGFSQGWWIVQDA
SAQLVGHLLDPQPGEVIIDACAAPGGKTTHIAELMKDEGKVWAGDRTASRLRKLKENAQRLNLHSIEICIGDSRNLPQFY
DVADRVLLDAPCSGLGTLHRHADARWRQTPESVQELSMLQKELLAHTSKFVKVGGVLVYATCTLHPAENEEVITEFVAGN
SDWQIEPPRPDSPYSAYTTPQGWLKVWPHNQDMDGFFMVRLRKTNVSE

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=315, Percent_Identity=31.1111111111111, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI76150623, Length=315, Percent_Identity=31.1111111111111, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI32698918, Length=193, Percent_Identity=40.9326424870466, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI270288818, Length=260, Percent_Identity=32.3076923076923, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI8922322, Length=260, Percent_Identity=32.3076923076923, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI23199998, Length=260, Percent_Identity=32.3076923076923, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI270288816, Length=260, Percent_Identity=32.3076923076923, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI39995082, Length=179, Percent_Identity=32.4022346368715, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI301336155, Length=179, Percent_Identity=32.4022346368715, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI11545785, Length=172, Percent_Identity=33.1395348837209, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI40316918, Length=204, Percent_Identity=28.4313725490196, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI2367212, Length=415, Percent_Identity=35.9036144578313, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI87081985, Length=274, Percent_Identity=33.5766423357664, Blast_Score=129, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17536757, Length=233, Percent_Identity=30.4721030042918, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71998419, Length=278, Percent_Identity=29.4964028776978, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI115534021, Length=278, Percent_Identity=29.4964028776978, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI25143471, Length=172, Percent_Identity=30.2325581395349, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324268, Length=278, Percent_Identity=31.6546762589928, Blast_Score=137, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6319447, Length=265, Percent_Identity=27.5471698113208, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI22024126, Length=314, Percent_Identity=28.9808917197452, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24668781, Length=253, Percent_Identity=31.2252964426877, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI21356513, Length=253, Percent_Identity=31.2252964426877, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI21355201, Length=271, Percent_Identity=25.830258302583, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21356579, Length=172, Percent_Identity=28.4883720930233, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19920494, Length=207, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 50387; Mature: 50256

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSRQIAFIALRDVHKGAYTDVALDRALQKANLSDIDRRLVTELLYGSVRRQRTLDFII
CCCCCEEEEEEEEHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQLAKKKSHQQPTELRSILHLGLYQLRYQERIPASAAVNTTVELAKDNGFAGLTGFVNGL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEEEECCCCCCHHHHHHHHH
LRQYIRLAEASPDFLELPENPVERLGILHSFPDWIIKVWWEQLGLTETEKLCEWMNQTPT
HHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
LDLRVNPLLASVAEVETALKSAGVLARPIPHLPQALRLIGNNGSIQKLPGFSQGWWIVQD
EEEEECHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEC
ASAQLVGHLLDPQPGEVIIDACAAPGGKTTHIAELMKDEGKVWAGDRTASRLRKLKENAQ
CHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHH
RLNLHSIEICIGDSRNLPQFYDVADRVLLDAPCSGLGTLHRHADARWRQTPESVQELSML
HCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHCCHHHHHHHHHH
QKELLAHTSKFVKVGGVLVYATCTLHPAENEEVITEFVAGNSDWQIEPPRPDSPYSAYTT
HHHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHCCCCCCEECCCCCCCCCCCCCC
PQGWLKVWPHNQDMDGFFMVRLRKTNVSE
CCCCEEECCCCCCCCCEEEEEEECCCCCC
>Mature Secondary Structure 
TNSRQIAFIALRDVHKGAYTDVALDRALQKANLSDIDRRLVTELLYGSVRRQRTLDFII
CCCCEEEEEEEEHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQLAKKKSHQQPTELRSILHLGLYQLRYQERIPASAAVNTTVELAKDNGFAGLTGFVNGL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEEEECCCCCCHHHHHHHHH
LRQYIRLAEASPDFLELPENPVERLGILHSFPDWIIKVWWEQLGLTETEKLCEWMNQTPT
HHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
LDLRVNPLLASVAEVETALKSAGVLARPIPHLPQALRLIGNNGSIQKLPGFSQGWWIVQD
EEEEECHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEC
ASAQLVGHLLDPQPGEVIIDACAAPGGKTTHIAELMKDEGKVWAGDRTASRLRKLKENAQ
CHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHH
RLNLHSIEICIGDSRNLPQFYDVADRVLLDAPCSGLGTLHRHADARWRQTPESVQELSML
HCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHCCHHHHHHHHHH
QKELLAHTSKFVKVGGVLVYATCTLHPAENEEVITEFVAGNSDWQIEPPRPDSPYSAYTT
HHHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHCCCCCCEECCCCCCCCCCCCCC
PQGWLKVWPHNQDMDGFFMVRLRKTNVSE
CCCCEEECCCCCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]