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The map label for this gene is rpe [H]

Identifier: 17228277

GI number: 17228277

Start: 905282

End: 905989

Strand: Direct

Name: rpe [H]

Synonym: alr0782

Alternate gene names: 17228277

Gene position: 905282-905989 (Clockwise)

Preceding gene: 17228275

Following gene: 17228279

Centisome position: 14.11

GC content: 45.06

Gene sequence:

>708_bases
ATGACCCAAAACCGATCTGAAAAACCCATAGTAATCTCTCCATCTATCCTATCAGCCGACTTTAGCCGCTTAGGTGACGA
AATTCGCGCTGTAGATGCAGCTGGAGCCGATTGGATTCATGTTGATGTAATGGACGGTCGTTTTGTACCTAATATTACGA
TAGGTCCTCTGGTAGTGGAGGCGATTCGTCCAGTTACAAAGAAACCTCTGGATGTCCACTTGATGATAGTGGAGCCAGAA
AAGTATGTAGAAGATTTTGCTAAAGCAGGCGCTGACATCATTTCTGTTCATTGTGAACATAACGCTTCACCACATCTGCA
CCGCACCCTGGGACAAATCAAAGAATTAGGTAAACAAGCAGGTGTCGTACTCAATCCTGGTACACCTTTAGAACTAATCG
AATATGTTCTAGAACTGTGCGACCTCATACTAATTATGAGTGTTAACCCCGGCTTTGGTGGTCAAAGCTTTATTCCTGGG
GTAGTACCCAAAATCCGCCAGTTGCGTCAAATGTGTGACGAACGCGGTTTAGACCCTTGGATTGAAGTAGACGGCGGGCT
AAAAGCTAACAATACTTGGCAAGTTTTAGAAGCAGGCGCGAATGCAATTGTGGCCGGTTCTGCTGTATTTAATGCTAAGG
ATTATGCAGAGGCGATTACTAATATTCGCAACAGCAAGCGTCCTACACCAGAATTGGCGAAGGTCTAG

Upstream 100 bases:

>100_bases
TCCTGTCTCCTACCCCTGCCTTTTTCTAAAATTCTCAATATTTTGTTACAGTATTTTGTTACAATGCTTACAGACGAGGA
CGCTTAAAAACCCACCAGCC

Downstream 100 bases:

>100_bases
GCTGACTGAATAGATAGAGAATAATCATAAAGTTAAGGGTGATAGTTCATTTATCACCCTTAACTTTATGATATTTGCGG
GAAAATATTAGACTTGAAGT

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MTQNRSEKPIVISPSILSADFSRLGDEIRAVDAAGADWIHVDVMDGRFVPNITIGPLVVEAIRPVTKKPLDVHLMIVEPE
KYVEDFAKAGADIISVHCEHNASPHLHRTLGQIKELGKQAGVVLNPGTPLELIEYVLELCDLILIMSVNPGFGGQSFIPG
VVPKIRQLRQMCDERGLDPWIEVDGGLKANNTWQVLEAGANAIVAGSAVFNAKDYAEAITNIRNSKRPTPELAKV

Sequences:

>Translated_235_residues
MTQNRSEKPIVISPSILSADFSRLGDEIRAVDAAGADWIHVDVMDGRFVPNITIGPLVVEAIRPVTKKPLDVHLMIVEPE
KYVEDFAKAGADIISVHCEHNASPHLHRTLGQIKELGKQAGVVLNPGTPLELIEYVLELCDLILIMSVNPGFGGQSFIPG
VVPKIRQLRQMCDERGLDPWIEVDGGLKANNTWQVLEAGANAIVAGSAVFNAKDYAEAITNIRNSKRPTPELAKV
>Mature_234_residues
TQNRSEKPIVISPSILSADFSRLGDEIRAVDAAGADWIHVDVMDGRFVPNITIGPLVVEAIRPVTKKPLDVHLMIVEPEK
YVEDFAKAGADIISVHCEHNASPHLHRTLGQIKELGKQAGVVLNPGTPLELIEYVLELCDLILIMSVNPGFGGQSFIPGV
VPKIRQLRQMCDERGLDPWIEVDGGLKANNTWQVLEAGANAIVAGSAVFNAKDYAEAITNIRNSKRPTPELAKV

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=215, Percent_Identity=40.9302325581395, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI219879828, Length=215, Percent_Identity=38.6046511627907, Blast_Score=142, Evalue=2e-34,
Organism=Homo sapiens, GI24307923, Length=171, Percent_Identity=33.9181286549708, Blast_Score=91, Evalue=6e-19,
Organism=Escherichia coli, GI1789788, Length=229, Percent_Identity=51.9650655021834, Blast_Score=231, Evalue=5e-62,
Organism=Escherichia coli, GI1790523, Length=201, Percent_Identity=37.8109452736318, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1790754, Length=213, Percent_Identity=31.4553990610329, Blast_Score=110, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17552948, Length=217, Percent_Identity=41.4746543778802, Blast_Score=159, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6322341, Length=229, Percent_Identity=41.4847161572052, Blast_Score=167, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24586301, Length=214, Percent_Identity=39.7196261682243, Blast_Score=157, Evalue=8e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 25583; Mature: 25452

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQNRSEKPIVISPSILSADFSRLGDEIRAVDAAGADWIHVDVMDGRFVPNITIGPLVVE
CCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEECCCCCHHHHHHH
AIRPVTKKPLDVHLMIVEPEKYVEDFAKAGADIISVHCEHNASPHLHRTLGQIKELGKQA
HHHHHHCCCCEEEEEEECCHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHC
GVVLNPGTPLELIEYVLELCDLILIMSVNPGFGGQSFIPGVVPKIRQLRQMCDERGLDPW
CEEECCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCE
IEVDGGLKANNTWQVLEAGANAIVAGSAVFNAKDYAEAITNIRNSKRPTPELAKV
EEECCCCCCCCCHHHHHCCCCEEEECCHHCCHHHHHHHHHHHHCCCCCCCHHHCC
>Mature Secondary Structure 
TQNRSEKPIVISPSILSADFSRLGDEIRAVDAAGADWIHVDVMDGRFVPNITIGPLVVE
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEECCCCCHHHHHHH
AIRPVTKKPLDVHLMIVEPEKYVEDFAKAGADIISVHCEHNASPHLHRTLGQIKELGKQA
HHHHHHCCCCEEEEEEECCHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHC
GVVLNPGTPLELIEYVLELCDLILIMSVNPGFGGQSFIPGVVPKIRQLRQMCDERGLDPW
CEEECCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCE
IEVDGGLKANNTWQVLEAGANAIVAGSAVFNAKDYAEAITNIRNSKRPTPELAKV
EEECCCCCCCCCHHHHHCCCCEEEECCHHCCHHHHHHHHHHHHCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231; 9298645 [H]