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The map label for this gene is ycjU [C]

Identifier: 17228223

GI number: 17228223

Start: 846315

End: 846992

Strand: Direct

Name: ycjU [C]

Synonym: alr0728

Alternate gene names: 17228223

Gene position: 846315-846992 (Clockwise)

Preceding gene: 17228220

Following gene: 17228225

Centisome position: 13.2

GC content: 41.45

Gene sequence:

>678_bases
ATGCTAACTGCGATTCTCTTTGATTTAGACGGTACTATCGTCAATACTGATCCTATACATTACCAAGCTTGGCGACAAAT
GTTGTGGAAATGCAACATAGAAATTGATGAAACATTTTATAAATCTCGAATTAGTGGTCGTTTAAACCCAGAAATTGTTA
AGGACATTCTGCCAGAATTATCATCAGCCGCAGGTAGAGAATTTGCCGATGAAAAAGAAGCCTTGTTTCGGGAACTAGCC
TCCCATCTTCAACCATTAAACGGATTTGCTGAACTCATAGCTTGGACAGAAGTACATCAGTTAAAACGTGCTTTAGTAAC
AAATGCTCCGAGATTAAACGCAGAGTTTATGTTGGAGGTATTGGGAATAACAGATAGTTTCCATCAAATTGTCTTGGCTG
ATGATTGCGTAGCGGGTAAACCAGATCCAGCACCTTATCAAGTTGCTTTGAGTAAGTTGGGGATTCCAGCAGAGAAGGCG
ATCGCTTTGGAAGATTCCCCCTCTGGGATTCGCGCAGCAGTTGGCGCAGGTATTCGTACTATTGGGATTGCCTCCACTCA
CGACCCTGATATTTTGCTGGAGGTTGGCTCATTTATGGCGATTCCTGATTTTACAGATTTACATTTGTGGACGTTACTAA
ACTCATTAATTGAGCCAGATTTAATTCGTAGTACGTGA

Upstream 100 bases:

>100_bases
AACCTTTAAGCTTCATGGCAGTCCGAGATGACTTAGGAACATAAAACAATGTAGACTATGTAAATTAAGTTAATAATTAT
TTACATTACATCCAAACATC

Downstream 100 bases:

>100_bases
TGGTTATACCAATTCAATGAGGACTTACACCCAGGATGTTTGTTAAGACTGGGTGTAAGGGTAGGATTACGAAATATCTT
TTATAGTACTAACTATCTCC

Product: hypothetical protein

Products: Beta-D-Glucose 6- Phosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MLTAILFDLDGTIVNTDPIHYQAWRQMLWKCNIEIDETFYKSRISGRLNPEIVKDILPELSSAAGREFADEKEALFRELA
SHLQPLNGFAELIAWTEVHQLKRALVTNAPRLNAEFMLEVLGITDSFHQIVLADDCVAGKPDPAPYQVALSKLGIPAEKA
IALEDSPSGIRAAVGAGIRTIGIASTHDPDILLEVGSFMAIPDFTDLHLWTLLNSLIEPDLIRST

Sequences:

>Translated_225_residues
MLTAILFDLDGTIVNTDPIHYQAWRQMLWKCNIEIDETFYKSRISGRLNPEIVKDILPELSSAAGREFADEKEALFRELA
SHLQPLNGFAELIAWTEVHQLKRALVTNAPRLNAEFMLEVLGITDSFHQIVLADDCVAGKPDPAPYQVALSKLGIPAEKA
IALEDSPSGIRAAVGAGIRTIGIASTHDPDILLEVGSFMAIPDFTDLHLWTLLNSLIEPDLIRST
>Mature_225_residues
MLTAILFDLDGTIVNTDPIHYQAWRQMLWKCNIEIDETFYKSRISGRLNPEIVKDILPELSSAAGREFADEKEALFRELA
SHLQPLNGFAELIAWTEVHQLKRALVTNAPRLNAEFMLEVLGITDSFHQIVLADDCVAGKPDPAPYQVALSKLGIPAEKA
IALEDSPSGIRAAVGAGIRTIGIASTHDPDILLEVGSFMAIPDFTDLHLWTLLNSLIEPDLIRST

Specific function: Displays high phosphatase activity toward erythrose 4- phosphate, fructose 6-phosphate, 2-deoxyglucose 6-phosphate, and mannose 6-phosphate. May have a role in the intracellular metabolism of many phosphorylated carbohydrates [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787576, Length=194, Percent_Identity=30.9278350515464, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1789046, Length=183, Percent_Identity=28.4153005464481, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321834, Length=224, Percent_Identity=27.2321428571429, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321833, Length=220, Percent_Identity=25.9090909090909, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20129151, Length=196, Percent_Identity=28.0612244897959, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 5.4.2.6 [C]

Molecular weight: Translated: 24841; Mature: 24841

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS01228 COF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTAILFDLDGTIVNTDPIHYQAWRQMLWKCNIEIDETFYKSRISGRLNPEIVKDILPEL
CCEEEEEECCCEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
SSAAGREFADEKEALFRELASHLQPLNGFAELIAWTEVHQLKRALVTNAPRLNAEFMLEV
HHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LGITDSFHQIVLADDCVAGKPDPAPYQVALSKLGIPAEKAIALEDSPSGIRAAVGAGIRT
HCCCCCHHEEEEECCCCCCCCCCCHHHHHHHHCCCCHHHEEEECCCCCHHHHHHHCCCCE
IGIASTHDPDILLEVGSFMAIPDFTDLHLWTLLNSLIEPDLIRST
EECCCCCCCHHHEECCCEEECCCCCHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MLTAILFDLDGTIVNTDPIHYQAWRQMLWKCNIEIDETFYKSRISGRLNPEIVKDILPEL
CCEEEEEECCCEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
SSAAGREFADEKEALFRELASHLQPLNGFAELIAWTEVHQLKRALVTNAPRLNAEFMLEV
HHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LGITDSFHQIVLADDCVAGKPDPAPYQVALSKLGIPAEKAIALEDSPSGIRAAVGAGIRT
HCCCCCHHEEEEECCCCCCCCCCCHHHHHHHHCCCCHHHEEEECCCCCHHHHHHHCCCCE
IGIASTHDPDILLEVGSFMAIPDFTDLHLWTLLNSLIEPDLIRST
EECCCCCCCHHHEECCCEEECCCCCHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Beta-D-Glucose 1-Phosphate [C]

Specific reaction: Beta-D-Glucose 1-Phosphate = Beta-D-Glucose 6- Phosphate. [C]

General reaction: Group transfer (intramolecular phosphate group isomerization [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]