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The map label for this gene is spoVD [H]

Identifier: 17228213

GI number: 17228213

Start: 835215

End: 837044

Strand: Direct

Name: spoVD [H]

Synonym: alr0718

Alternate gene names: 17228213

Gene position: 835215-837044 (Clockwise)

Preceding gene: 17228212

Following gene: 17228214

Centisome position: 13.02

GC content: 45.25

Gene sequence:

>1830_bases
ATGCAAAAGTCACCAAGTAGATTGAAGTTTAGAAAGTTTCAAAAGCCGGAGTTCACCAGGCGCAAAAGGGTATTACAAAA
GGTGGCAATGAAAACAATTGCCCCCAATCCCCAAGAGCCATTAACAAATGCCAAAACCAGACTTTTGACTGTCTGGGGTA
TATTAATGACGGCTGGACTGGGATTGGCAATTAATGCGTATAACTTGCAAATTTTGCAGGGAGCAAAACTAACACAAAGA
GCGCGAAACCAACAAATGGTAAGCTTGCGCCCCTATATGCCTCGCCGCTTGGTGGTGGATCGCAATGATAATGTGTTGGC
TGTTGACCGCCCTGTCTATACTTTATATGCCCACCCTAAGCTATTTAAAAAGACAAATGAAGAAATAAGCGATCGCCTAG
CTCCCATTATTGATAGAAACCCTGCTGATTTAGTCAAGATTTTTCAAGGTCAAAAAAGTGGTATTACTTTGACCTCCTCT
TTACCAGAGGAACTGGCCGAGCGCGTCAGGAAATTAAGATTAGATGGCTTGGAAATGATTCCCAAATATTCCCGCTATTA
TCCTCAGGATGATTTAGTGGCGGATGTAGTGGGATATGTAGACGTTGACCGTCGTGGTCAGGCGGGTGTGGAACGTAGCC
AAGAGAAATGGCTAGAACGTTCTGTGAAAACAGTACGCTTAAGTAGGGCGGGTAATGGGGCTTTGATGCCTGATTATGCT
CCTGAAGGTTTTTTAAATTCTGATGATTTGCGGATGCAATTGACTATCGACAGTCGTTTGCAAAGGGCTACCCGAACAGC
ATTGAAGGAACAGCTAGAAAAGTTTGGCGGGAAACGAGGAGCAGTGATTGTGATGGATGCGATGGATGGCTCTATCCTCG
CTTTGGCATCTCAACCTACTTATAACCCGAATGAATACTCGAAAGCGGATATTTCATTGTTCAAAAACTGGACGGTGGCT
GATCTCTATGAGCCAGGTTCCACATTTAAACCATTGAATGTGGCGATCGCTCTGGAAAATGGTGTCATCAAAGCAGATGA
TGTATTTAATGATTCCGGTGCAATTCGCATCGGTTCTCATACTATTAGAAACGCTCAACGCAACGGTTACGGACGCATCA
ATATTGCTCAAATTCTCCAAAACTCCAGCAATATTGGCATGGTGCAGATGATCCAACGCCTAAAACCTTCGATTTACTAC
AATTGGCTAGAACGTTTAGGACTAGGTCAACCGGTAGATACAGATTTACCTTTTGCCGTGAGTGGGACGCTCAAAAGTCA
GGAAAAATTTATTCGCTCCCCCATTGAACCAGCAACCACTTCCTTTGGACAAGGCTTTTCTTTGACACCCTTACAATTAG
TGCAGATGCAAGGAGCCTTAGCTAATGGTGGTAAATTGGTCACACCTCACGTTGTCCGGGGACTACTTGATACTAAAGGG
CAAATCCACTACACACCCAATCACCCAGCACCAAGGCAAATTTTCTCAGCCGCAACGACCCAAAAAGTTGTGGAAATGAT
GGAAACGGTAGTTACAGAAGGTACTGGCAAGGCTGCTCAAATCCCTGGCTATCGCATCGCAGGCAAAACAGGTACAGCCC
AAAAAGCCAGTCCTAACGGCGGTTACATCGTGGGCGCTCGGATTACCAGCTTTGTTGCTATTTTACCCGTTGAATCACCC
CGTTATGTAGTTTTGGCCTTAGTTGATGAGCCAAAAGGAGCCAACGCCTACGGTTCAACTGTCGCAGCCCCAATTGTCAA
ATCCGTTATGGAAGCACTAATTCCCATTGAACGCCTTGCACCCAGCCAGCCGATTGAAGGAAAACCTTAA

Upstream 100 bases:

>100_bases
ATGTAAACAGCTATCGAGTATGTGGTATTGTAGTTCACACCTGCGATGAGACTGATAGCTGAAAACTGAATAACTCACAA
CTGACTAACTGAGCAGAGTA

Downstream 100 bases:

>100_bases
GTAGGAAGAAGGGGAAAATCAAATTAGTGCCAACTAACAACTGACAACTGACTAACAACCAATGACTTTTTTCTTTATTA
CCGGAGAAAGAGGTAGACAA

Product: penicillin-binding protein

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 609; Mature: 609

Protein sequence:

>609_residues
MQKSPSRLKFRKFQKPEFTRRKRVLQKVAMKTIAPNPQEPLTNAKTRLLTVWGILMTAGLGLAINAYNLQILQGAKLTQR
ARNQQMVSLRPYMPRRLVVDRNDNVLAVDRPVYTLYAHPKLFKKTNEEISDRLAPIIDRNPADLVKIFQGQKSGITLTSS
LPEELAERVRKLRLDGLEMIPKYSRYYPQDDLVADVVGYVDVDRRGQAGVERSQEKWLERSVKTVRLSRAGNGALMPDYA
PEGFLNSDDLRMQLTIDSRLQRATRTALKEQLEKFGGKRGAVIVMDAMDGSILALASQPTYNPNEYSKADISLFKNWTVA
DLYEPGSTFKPLNVAIALENGVIKADDVFNDSGAIRIGSHTIRNAQRNGYGRINIAQILQNSSNIGMVQMIQRLKPSIYY
NWLERLGLGQPVDTDLPFAVSGTLKSQEKFIRSPIEPATTSFGQGFSLTPLQLVQMQGALANGGKLVTPHVVRGLLDTKG
QIHYTPNHPAPRQIFSAATTQKVVEMMETVVTEGTGKAAQIPGYRIAGKTGTAQKASPNGGYIVGARITSFVAILPVESP
RYVVLALVDEPKGANAYGSTVAAPIVKSVMEALIPIERLAPSQPIEGKP

Sequences:

>Translated_609_residues
MQKSPSRLKFRKFQKPEFTRRKRVLQKVAMKTIAPNPQEPLTNAKTRLLTVWGILMTAGLGLAINAYNLQILQGAKLTQR
ARNQQMVSLRPYMPRRLVVDRNDNVLAVDRPVYTLYAHPKLFKKTNEEISDRLAPIIDRNPADLVKIFQGQKSGITLTSS
LPEELAERVRKLRLDGLEMIPKYSRYYPQDDLVADVVGYVDVDRRGQAGVERSQEKWLERSVKTVRLSRAGNGALMPDYA
PEGFLNSDDLRMQLTIDSRLQRATRTALKEQLEKFGGKRGAVIVMDAMDGSILALASQPTYNPNEYSKADISLFKNWTVA
DLYEPGSTFKPLNVAIALENGVIKADDVFNDSGAIRIGSHTIRNAQRNGYGRINIAQILQNSSNIGMVQMIQRLKPSIYY
NWLERLGLGQPVDTDLPFAVSGTLKSQEKFIRSPIEPATTSFGQGFSLTPLQLVQMQGALANGGKLVTPHVVRGLLDTKG
QIHYTPNHPAPRQIFSAATTQKVVEMMETVVTEGTGKAAQIPGYRIAGKTGTAQKASPNGGYIVGARITSFVAILPVESP
RYVVLALVDEPKGANAYGSTVAAPIVKSVMEALIPIERLAPSQPIEGKP
>Mature_609_residues
MQKSPSRLKFRKFQKPEFTRRKRVLQKVAMKTIAPNPQEPLTNAKTRLLTVWGILMTAGLGLAINAYNLQILQGAKLTQR
ARNQQMVSLRPYMPRRLVVDRNDNVLAVDRPVYTLYAHPKLFKKTNEEISDRLAPIIDRNPADLVKIFQGQKSGITLTSS
LPEELAERVRKLRLDGLEMIPKYSRYYPQDDLVADVVGYVDVDRRGQAGVERSQEKWLERSVKTVRLSRAGNGALMPDYA
PEGFLNSDDLRMQLTIDSRLQRATRTALKEQLEKFGGKRGAVIVMDAMDGSILALASQPTYNPNEYSKADISLFKNWTVA
DLYEPGSTFKPLNVAIALENGVIKADDVFNDSGAIRIGSHTIRNAQRNGYGRINIAQILQNSSNIGMVQMIQRLKPSIYY
NWLERLGLGQPVDTDLPFAVSGTLKSQEKFIRSPIEPATTSFGQGFSLTPLQLVQMQGALANGGKLVTPHVVRGLLDTKG
QIHYTPNHPAPRQIFSAATTQKVVEMMETVVTEGTGKAAQIPGYRIAGKTGTAQKASPNGGYIVGARITSFVAILPVESP
RYVVLALVDEPKGANAYGSTVAAPIVKSVMEALIPIERLAPSQPIEGKP

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=588, Percent_Identity=30.2721088435374, Blast_Score=237, Evalue=2e-63,
Organism=Escherichia coli, GI1786854, Length=609, Percent_Identity=26.2725779967159, Blast_Score=140, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 67258; Mature: 67258

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKSPSRLKFRKFQKPEFTRRKRVLQKVAMKTIAPNPQEPLTNAKTRLLTVWGILMTAGL
CCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCC
GLAINAYNLQILQGAKLTQRARNQQMVSLRPYMPRRLVVDRNDNVLAVDRPVYTLYAHPK
CEEEEEEEEEEECCCHHHHHHHCCCEEEECCCCCCEEEEECCCCEEEECCCEEEEECCCH
LFKKTNEEISDRLAPIIDRNPADLVKIFQGQKSGITLTSSLPEELAERVRKLRLDGLEMI
HHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHC
PKYSRYYPQDDLVADVVGYVDVDRRGQAGVERSQEKWLERSVKTVRLSRAGNGALMPDYA
CHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCC
PEGFLNSDDLRMQLTIDSRLQRATRTALKEQLEKFGGKRGAVIVMDAMDGSILALASQPT
CCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCC
YNPNEYSKADISLFKNWTVADLYEPGSTFKPLNVAIALENGVIKADDVFNDSGAIRIGSH
CCCCCCCCHHHHHHCCCCEEEEECCCCCCCCEEEEEEEECCEEECCCCCCCCCCEEECCH
TIRNAQRNGYGRINIAQILQNSSNIGMVQMIQRLKPSIYYNWLERLGLGQPVDTDLPFAV
HHHHHHCCCCCCEEHHHHHCCCCCCCHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCEEE
SGTLKSQEKFIRSPIEPATTSFGQGFSLTPLQLVQMQGALANGGKLVTPHVVRGLLDTKG
ECCHHHHHHHHHCCCCCCHHCCCCCCCCCHHHHHHHHCHHCCCCEEECHHHHHHHHCCCC
QIHYTPNHPAPRQIFSAATTQKVVEMMETVVTEGTGKAAQIPGYRIAGKTGTAQKASPNG
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEECCCCCCCCCCCCC
GYIVGARITSFVAILPVESPRYVVLALVDEPKGANAYGSTVAAPIVKSVMEALIPIERLA
CEEEEEHHHEEEEEEECCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHCC
PSQPIEGKP
CCCCCCCCC
>Mature Secondary Structure
MQKSPSRLKFRKFQKPEFTRRKRVLQKVAMKTIAPNPQEPLTNAKTRLLTVWGILMTAGL
CCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCC
GLAINAYNLQILQGAKLTQRARNQQMVSLRPYMPRRLVVDRNDNVLAVDRPVYTLYAHPK
CEEEEEEEEEEECCCHHHHHHHCCCEEEECCCCCCEEEEECCCCEEEECCCEEEEECCCH
LFKKTNEEISDRLAPIIDRNPADLVKIFQGQKSGITLTSSLPEELAERVRKLRLDGLEMI
HHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHC
PKYSRYYPQDDLVADVVGYVDVDRRGQAGVERSQEKWLERSVKTVRLSRAGNGALMPDYA
CHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCC
PEGFLNSDDLRMQLTIDSRLQRATRTALKEQLEKFGGKRGAVIVMDAMDGSILALASQPT
CCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCC
YNPNEYSKADISLFKNWTVADLYEPGSTFKPLNVAIALENGVIKADDVFNDSGAIRIGSH
CCCCCCCCHHHHHHCCCCEEEEECCCCCCCCEEEEEEEECCEEECCCCCCCCCCEEECCH
TIRNAQRNGYGRINIAQILQNSSNIGMVQMIQRLKPSIYYNWLERLGLGQPVDTDLPFAV
HHHHHHCCCCCCEEHHHHHCCCCCCCHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCEEE
SGTLKSQEKFIRSPIEPATTSFGQGFSLTPLQLVQMQGALANGGKLVTPHVVRGLLDTKG
ECCHHHHHHHHHCCCCCCHHCCCCCCCCCHHHHHHHHCHHCCCCEEECHHHHHHHHCCCC
QIHYTPNHPAPRQIFSAATTQKVVEMMETVVTEGTGKAAQIPGYRIAGKTGTAQKASPNG
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEECCCCCCCCCCCCC
GYIVGARITSFVAILPVESPRYVVLALVDEPKGANAYGSTVAAPIVKSVMEALIPIERLA
CEEEEEHHHEEEEEEECCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHCC
PSQPIEGKP
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]