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The map label for this gene is hupA

Identifier: 17228194

GI number: 17228194

Start: 806012

End: 806353

Strand: Direct

Name: hupA

Synonym: alr0699

Alternate gene names: 17228194

Gene position: 806012-806353 (Clockwise)

Preceding gene: 17228193

Following gene: 17228195

Centisome position: 12.57

GC content: 35.09

Gene sequence:

>342_bases
ATGCACGAACTAGGAATTACACAAAATATCGTAGCTATTGTTAGTGAATATGCTCAAGGCTCAAAAGTAAACCGAATTTT
ATTAGAAATCGGTAAACTTTCGGCTATTATGCCTGATGCTGTGCAATTTTGTTTTGATATTTGTAGTAAAGGTACGTCTT
TAGAAGGTGCAGTCTTAGAAATTAGAGAAATTCCGGGTTTAGCTAAATGTCGCCAATGTGGTGCAGAAATTGCTTTAGAA
AAACCATTTGGTATTTGTGGTTGTGGTAGTGTGCATTTAGATGTAATTACTGGTGAAGAACTGAAAATCAAAGAAATAGA
GGTCGAAGAAGTATGTGTGTAA

Upstream 100 bases:

>100_bases
AGTAGTTTTTCTAAAAACTACTTTTGGTACAGAACGGATTGTTGATATGCTAGTCGGTGAGCAATTACCGCGTATTTGTT
AATTATAAGTAGAGCGTTTC

Downstream 100 bases:

>100_bases
CCTGTGGTTGTTCTGATGAGTCTGAAGATAAAATTACTAATTTAGAAACAGGCGAAATGGTACATAATCACCATCATCAT
ACTCACACCTTAGCTGATGG

Product: hydrogenase expression/formation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MHELGITQNIVAIVSEYAQGSKVNRILLEIGKLSAIMPDAVQFCFDICSKGTSLEGAVLEIREIPGLAKCRQCGAEIALE
KPFGICGCGSVHLDVITGEELKIKEIEVEEVCV

Sequences:

>Translated_113_residues
MHELGITQNIVAIVSEYAQGSKVNRILLEIGKLSAIMPDAVQFCFDICSKGTSLEGAVLEIREIPGLAKCRQCGAEIALE
KPFGICGCGSVHLDVITGEELKIKEIEVEEVCV
>Mature_113_residues
MHELGITQNIVAIVSEYAQGSKVNRILLEIGKLSAIMPDAVQFCFDICSKGTSLEGAVLEIREIPGLAKCRQCGAEIALE
KPFGICGCGSVHLDVITGEELKIKEIEVEEVCV

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789365, Length=113, Percent_Identity=37.1681415929204, Blast_Score=64, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_NOSS1 (O30461)

Other databases:

- EMBL:   AF006594
- EMBL:   BA000019
- PIR:   AI1893
- RefSeq:   NP_484742.1
- STRING:   O30461
- GeneID:   1104294
- GenomeReviews:   BA000019_GR
- KEGG:   ana:alr0699
- NMPDR:   fig|103690.1.peg.1009
- eggNOG:   COG0375
- HOGENOM:   HBG688671
- OMA:   IAGNEFF
- PhylomeDB:   O30461
- ProtClustDB:   CLSK895358
- BioCyc:   NSP103690:ALR0699-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 12161; Mature: 12161

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
6.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELGITQNIVAIVSEYAQGSKVNRILLEIGKLSAIMPDAVQFCFDICSKGTSLEGAVLE
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHH
IREIPGLAKCRQCGAEIALEKPFGICGCGSVHLDVITGEELKIKEIEVEEVCV
HHHCCCHHHHHHCCCCEEECCCCCEEECCCEEEEEEECCCEEEEEECHHHHCC
>Mature Secondary Structure
MHELGITQNIVAIVSEYAQGSKVNRILLEIGKLSAIMPDAVQFCFDICSKGTSLEGAVLE
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHH
IREIPGLAKCRQCGAEIALEKPFGICGCGSVHLDVITGEELKIKEIEVEEVCV
HHHCCCHHHHHHCCCCEEECCCCCEEECCCEEEEEEECCCEEEEEECHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840