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The map label for this gene is thyX [H]

Identifier: 17228011

GI number: 17228011

Start: 607888

End: 608610

Strand: Direct

Name: thyX [H]

Synonym: alr0515

Alternate gene names: 17228011

Gene position: 607888-608610 (Clockwise)

Preceding gene: 17228008

Following gene: 17228012

Centisome position: 9.48

GC content: 43.57

Gene sequence:

>723_bases
ATGGATCGATTCCGAGTAGAAGTTATAGCTAAAACACCAAACCCCCAGCAGGTAATTTACGCCGCAATGCACCAAGATTA
TACGGATGGGTTCGTGTTTGATGAGCGCGACTCCTGGCCCTCGGAGTCCGAATGTGGCGACATTATTATTAAACGCCTGT
TAGCTGGGGAAAGAGGACACTATGGCCCGTTAGAGCATCCCCAGATTGTTTTCAACTGCGGCTATTTTCCCCACAGCGTT
ATGCAGCAGGCGCGTACGCATAGAGTTTCAGTATCATTTGATGTGCAATCTTTTAGGTATACGGGTAACCAGTTTATTGA
TGTAGTCGAAGGTATAAAAGACATTGAAGATGTTTTTTACCTCCGTCCTGTTGGTTATTACACAGATAGACAGGGCAAAA
AATATTACTATTCTCCAGAACAAAGAGCCGCAGATTTGCAGTGGTGTTTAGAAGCAGCTAAACGTTACAAAGCTGATTTT
GAAGGGGGAATGTCTGAAGAACACGCACGGGGTAAAGTACCTTTTGATTATCGCCAGCATTTTGTCGTCAGCTTTAATCT
TCGTTCATTTTTGCACTTTTGTGATTTACGCAATAAGAAAGATGCACAACTAGAAATTCAAAAGTTGTGTGAACTGATGT
GGCCTCATTTTGCAGAGTGGTCTCCGGCGATCGCTCAATGGTATGAAAAAGCCCGTCTAGGTAGAGCCAGACTATCACCA
TAA

Upstream 100 bases:

>100_bases
ATCTGAAGATATATCATGGTGAATCGAGTTCACAAATACGTCTAAAGAACACCCCTAGCTTTTAGACAATCCTAGTTACA
CATAAAACTCCCAGAAGCCA

Downstream 100 bases:

>100_bases
TTCAGACCGCTTTCCACTTATAGGTGTAATGTTATCGACCCTCGGCTAGCCGAGGGTTTTTCGTTACAATTCATCCCTAT
TTCCCTCGCTACTAGAGATC

Product: hypothetical protein

Products: NA

Alternate protein names: TS; TSase [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MDRFRVEVIAKTPNPQQVIYAAMHQDYTDGFVFDERDSWPSESECGDIIIKRLLAGERGHYGPLEHPQIVFNCGYFPHSV
MQQARTHRVSVSFDVQSFRYTGNQFIDVVEGIKDIEDVFYLRPVGYYTDRQGKKYYYSPEQRAADLQWCLEAAKRYKADF
EGGMSEEHARGKVPFDYRQHFVVSFNLRSFLHFCDLRNKKDAQLEIQKLCELMWPHFAEWSPAIAQWYEKARLGRARLSP

Sequences:

>Translated_240_residues
MDRFRVEVIAKTPNPQQVIYAAMHQDYTDGFVFDERDSWPSESECGDIIIKRLLAGERGHYGPLEHPQIVFNCGYFPHSV
MQQARTHRVSVSFDVQSFRYTGNQFIDVVEGIKDIEDVFYLRPVGYYTDRQGKKYYYSPEQRAADLQWCLEAAKRYKADF
EGGMSEEHARGKVPFDYRQHFVVSFNLRSFLHFCDLRNKKDAQLEIQKLCELMWPHFAEWSPAIAQWYEKARLGRARLSP
>Mature_240_residues
MDRFRVEVIAKTPNPQQVIYAAMHQDYTDGFVFDERDSWPSESECGDIIIKRLLAGERGHYGPLEHPQIVFNCGYFPHSV
MQQARTHRVSVSFDVQSFRYTGNQFIDVVEGIKDIEDVFYLRPVGYYTDRQGKKYYYSPEQRAADLQWCLEAAKRYKADF
EGGMSEEHARGKVPFDYRQHFVVSFNLRSFLHFCDLRNKKDAQLEIQKLCELMWPHFAEWSPAIAQWYEKARLGRARLSP

Specific function: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate [H]

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thyX (flavin-dependent thymidylate synthase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: =2.1.1.148 [H]

Molecular weight: Translated: 28254; Mature: 28254

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRFRVEVIAKTPNPQQVIYAAMHQDYTDGFVFDERDSWPSESECGDIIIKRLLAGERGH
CCCEEEEEEEECCCHHHHHHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHHHCCCCCC
YGPLEHPQIVFNCGYFPHSVMQQARTHRVSVSFDVQSFRYTGNQFIDVVEGIKDIEDVFY
CCCCCCCEEEEECCCCCHHHHHHHHHHEEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHH
LRPVGYYTDRQGKKYYYSPEQRAADLQWCLEAAKRYKADFEGGMSEEHARGKVPFDYRQH
HCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCHHCCCE
FVVSFNLRSFLHFCDLRNKKDAQLEIQKLCELMWPHFAEWSPAIAQWYEKARLGRARLSP
EEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDRFRVEVIAKTPNPQQVIYAAMHQDYTDGFVFDERDSWPSESECGDIIIKRLLAGERGH
CCCEEEEEEEECCCHHHHHHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHHHCCCCCC
YGPLEHPQIVFNCGYFPHSVMQQARTHRVSVSFDVQSFRYTGNQFIDVVEGIKDIEDVFY
CCCCCCCEEEEECCCCCHHHHHHHHHHEEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHH
LRPVGYYTDRQGKKYYYSPEQRAADLQWCLEAAKRYKADFEGGMSEEHARGKVPFDYRQH
HCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCHHCCCE
FVVSFNLRSFLHFCDLRNKKDAQLEIQKLCELMWPHFAEWSPAIAQWYEKARLGRARLSP
EEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA