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The map label for this gene is hsdM [C]

Identifier: 17227995

GI number: 17227995

Start: 595610

End: 597223

Strand: Direct

Name: hsdM [C]

Synonym: alr0499

Alternate gene names: 17227995

Gene position: 595610-597223 (Clockwise)

Preceding gene: 17227990

Following gene: 17227996

Centisome position: 9.29

GC content: 44.55

Gene sequence:

>1614_bases
ATGACGAACGGACAAAACGGACAAAAGAAAAAATTAGAAACCCAGCTTTGGAATATTGCCGACTCGCTGCGGGGCAAAAT
GAATGCTGATGAGTTTCGGGATTATTGCTTAGGGTTTATTTTTTACAAGTACCTGTCTGAGCGTCAGCATCTTTATGCTA
ATGAGGTGTTAGCAGAGGATGGCATTGATTTTATCAATATTGATGAATCTTCCAAAGAAGGACAAGAATATTTAGAGGCG
ATTAAAGAGGAGTCAATCGCCACCCTGGGGTATTTTCTCAAGCCGTCAGAGTTGTTTAGTTCCTTAGCAGAACGGGCTTT
AGGGGCGAAAACAGCCAGTGAGGAAAATCTGGCAGATGAGGATTTTGAAGCATCTAACTTTATTTTAGATGACTTGACCC
AAGTGCTGAGTAGTATTGAACGCTCGACAATGGGGAAGGAAAGCGAAGAGGATTTTGATCACTTGTTTGAGGATCTGGAT
CTCACTTCCACTAAGTTGGGGCGGACTCCCAAAGCGAAGAATGCTTTAATTGCTAAGATTTTAGTGCATCTCAATAAAAT
TGACTTTCGCCTAGAGGATACGGAAAGCGATGTATTGGGCGATGCTTACGAATATTTAATTGGGCAGTTTGCTAGTGGTG
CAGGGAAAAAAGCCGGGGAGTTTTACACGCCGCAGCAGGTTTCTAAGGTGTTGGCGAAGATTGTCACCACGGGGAAAAGT
CGCCTGAAGTCGGTTTATGATCCCACCTGTGGTTCGGGTTCGTTGCTGTTGCGGGTGGCGCGGGAGGTGGAATCAGTCGG
GGATTTTTACGGGCAAGAAATGAACCGCACAACCTACAACCTGGCGCGAATGAATATGATTTTGCATGGGGTGCATTATC
GTAATTTCGATTTGCGCCAGGAAGATACCCTAGAGAATCCCCAGCATGAGGGTATGCGGTTTGAGGCGGTGGTGGCAAAT
CCGCCGTTTTCGGCACAGTGGAGTGCTAATAAACTATTTGAGTCGGATGATCGCTTTAGTCAGTATGGCAAGTTAGCCCC
GGCTTCTAAGGCTGATTTTGCCTTTGTACAACACATGATCCATCACCTAGATGATAATGGGATTATGGCGGTGGTGTTGC
CTCATGGGGTTTTGTTTCGTGGTGCGGCGGAGGGACATATTCGCAAGTATGTGATCAAGGAACGCAATTGGTTAGATGCG
GTGATTGGATTGCCTGCGAATATATTTTATGGGACGAGTATCCCGACTTGTATTTTAGTGTTTAAAAAGTGCCGAGAAAA
TCCTGACGATATTTTATTTATTGATGCTAGTGCCTATTTTGAAAAGGCAAAGAATCAGAATTATTTGCGGGATGAGGATG
TAGAGAAAATTGTTTCTACCTATCGGCAAAGGATACAGTCAGAAAAGTATAGTTATCGCGCCCCATTAACGGAAATTGCG
GAGAATGATTTTAATTTAAATATTCCCCGGTATGTGGATACTTTTGAGGAAGAGGAGGAGATTGATTTAGATGCGGTGGC
GCGGGAAATTCGGGAGATTGATCGGGAGATGGTGGAGACGGATCAATTAATTCGCGGGTTTTGTGAGGAATTGGGGATTG
AGTCACCGTTTTAG

Upstream 100 bases:

>100_bases
AAATTCATCAATTTTTCATGAATTCTGCTTATGTGTTAATCTTACGTTGCTTAGATACCGATTCTTAGCGGTGCTAGCGA
TCGCCCAGTACAAGAGATAA

Downstream 100 bases:

>100_bases
GGGTTGTTTGAAAAGTATTATATGAAACCCATAATTTCCAAAAACCTAACCCCCCTACCCCCATTCCCTTGTAGGGAAGG
GGGGAAATTCAAAGCCTCTC

Product: type I site-specific deoxyribonuclease

Products: NA

Alternate protein names: M.MpnORFDP [H]

Number of amino acids: Translated: 537; Mature: 536

Protein sequence:

>537_residues
MTNGQNGQKKKLETQLWNIADSLRGKMNADEFRDYCLGFIFYKYLSERQHLYANEVLAEDGIDFINIDESSKEGQEYLEA
IKEESIATLGYFLKPSELFSSLAERALGAKTASEENLADEDFEASNFILDDLTQVLSSIERSTMGKESEEDFDHLFEDLD
LTSTKLGRTPKAKNALIAKILVHLNKIDFRLEDTESDVLGDAYEYLIGQFASGAGKKAGEFYTPQQVSKVLAKIVTTGKS
RLKSVYDPTCGSGSLLLRVAREVESVGDFYGQEMNRTTYNLARMNMILHGVHYRNFDLRQEDTLENPQHEGMRFEAVVAN
PPFSAQWSANKLFESDDRFSQYGKLAPASKADFAFVQHMIHHLDDNGIMAVVLPHGVLFRGAAEGHIRKYVIKERNWLDA
VIGLPANIFYGTSIPTCILVFKKCRENPDDILFIDASAYFEKAKNQNYLRDEDVEKIVSTYRQRIQSEKYSYRAPLTEIA
ENDFNLNIPRYVDTFEEEEEIDLDAVAREIREIDREMVETDQLIRGFCEELGIESPF

Sequences:

>Translated_537_residues
MTNGQNGQKKKLETQLWNIADSLRGKMNADEFRDYCLGFIFYKYLSERQHLYANEVLAEDGIDFINIDESSKEGQEYLEA
IKEESIATLGYFLKPSELFSSLAERALGAKTASEENLADEDFEASNFILDDLTQVLSSIERSTMGKESEEDFDHLFEDLD
LTSTKLGRTPKAKNALIAKILVHLNKIDFRLEDTESDVLGDAYEYLIGQFASGAGKKAGEFYTPQQVSKVLAKIVTTGKS
RLKSVYDPTCGSGSLLLRVAREVESVGDFYGQEMNRTTYNLARMNMILHGVHYRNFDLRQEDTLENPQHEGMRFEAVVAN
PPFSAQWSANKLFESDDRFSQYGKLAPASKADFAFVQHMIHHLDDNGIMAVVLPHGVLFRGAAEGHIRKYVIKERNWLDA
VIGLPANIFYGTSIPTCILVFKKCRENPDDILFIDASAYFEKAKNQNYLRDEDVEKIVSTYRQRIQSEKYSYRAPLTEIA
ENDFNLNIPRYVDTFEEEEEIDLDAVAREIREIDREMVETDQLIRGFCEELGIESPF
>Mature_536_residues
TNGQNGQKKKLETQLWNIADSLRGKMNADEFRDYCLGFIFYKYLSERQHLYANEVLAEDGIDFINIDESSKEGQEYLEAI
KEESIATLGYFLKPSELFSSLAERALGAKTASEENLADEDFEASNFILDDLTQVLSSIERSTMGKESEEDFDHLFEDLDL
TSTKLGRTPKAKNALIAKILVHLNKIDFRLEDTESDVLGDAYEYLIGQFASGAGKKAGEFYTPQQVSKVLAKIVTTGKSR
LKSVYDPTCGSGSLLLRVAREVESVGDFYGQEMNRTTYNLARMNMILHGVHYRNFDLRQEDTLENPQHEGMRFEAVVANP
PFSAQWSANKLFESDDRFSQYGKLAPASKADFAFVQHMIHHLDDNGIMAVVLPHGVLFRGAAEGHIRKYVIKERNWLDAV
IGLPANIFYGTSIPTCILVFKKCRENPDDILFIDASAYFEKAKNQNYLRDEDVEKIVSTYRQRIQSEKYSYRAPLTEIAE
NDFNLNIPRYVDTFEEEEEIDLDAVAREIREIDREMVETDQLIRGFCEELGIESPF

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=391, Percent_Identity=25.3196930946292, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR004546 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 61233; Mature: 61102

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNGQNGQKKKLETQLWNIADSLRGKMNADEFRDYCLGFIFYKYLSERQHLYANEVLAED
CCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GIDFINIDESSKEGQEYLEAIKEESIATLGYFLKPSELFSSLAERALGAKTASEENLADE
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCC
DFEASNFILDDLTQVLSSIERSTMGKESEEDFDHLFEDLDLTSTKLGRTPKAKNALIAKI
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHH
LVHLNKIDFRLEDTESDVLGDAYEYLIGQFASGAGKKAGEFYTPQQVSKVLAKIVTTGKS
HHHHHHHCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RLKSVYDPTCGSGSLLLRVAREVESVGDFYGQEMNRTTYNLARMNMILHGVHYRNFDLRQ
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCC
EDTLENPQHEGMRFEAVVANPPFSAQWSANKLFESDDRFSQYGKLAPASKADFAFVQHMI
HHCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHH
HHLDDNGIMAVVLPHGVLFRGAAEGHIRKYVIKERNWLDAVIGLPANIFYGTSIPTCILV
HHCCCCCEEEEEECCCHHCCCCCHHHHHHHHHHHCHHHHHHHCCCCCEEECCCHHHHHHH
FKKCRENPDDILFIDASAYFEKAKNQNYLRDEDVEKIVSTYRQRIQSEKYSYRAPLTEIA
HHHHCCCCCCEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ENDFNLNIPRYVDTFEEEEEIDLDAVAREIREIDREMVETDQLIRGFCEELGIESPF
CCCCCCCCCHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TNGQNGQKKKLETQLWNIADSLRGKMNADEFRDYCLGFIFYKYLSERQHLYANEVLAED
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GIDFINIDESSKEGQEYLEAIKEESIATLGYFLKPSELFSSLAERALGAKTASEENLADE
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCC
DFEASNFILDDLTQVLSSIERSTMGKESEEDFDHLFEDLDLTSTKLGRTPKAKNALIAKI
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHH
LVHLNKIDFRLEDTESDVLGDAYEYLIGQFASGAGKKAGEFYTPQQVSKVLAKIVTTGKS
HHHHHHHCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RLKSVYDPTCGSGSLLLRVAREVESVGDFYGQEMNRTTYNLARMNMILHGVHYRNFDLRQ
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCC
EDTLENPQHEGMRFEAVVANPPFSAQWSANKLFESDDRFSQYGKLAPASKADFAFVQHMI
HHCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHH
HHLDDNGIMAVVLPHGVLFRGAAEGHIRKYVIKERNWLDAVIGLPANIFYGTSIPTCILV
HHCCCCCEEEEEECCCHHCCCCCHHHHHHHHHHHCHHHHHHHCCCCCEEECCCHHHHHHH
FKKCRENPDDILFIDASAYFEKAKNQNYLRDEDVEKIVSTYRQRIQSEKYSYRAPLTEIA
HHHHCCCCCCEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ENDFNLNIPRYVDTFEEEEEIDLDAVAREIREIDREMVETDQLIRGFCEELGIESPF
CCCCCCCCCHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]