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The map label for this gene is engA [H]

Identifier: 17227979

GI number: 17227979

Start: 577593

End: 578954

Strand: Direct

Name: engA [H]

Synonym: alr0483

Alternate gene names: 17227979

Gene position: 577593-578954 (Clockwise)

Preceding gene: 17227978

Following gene: 17227980

Centisome position: 9.01

GC content: 46.62

Gene sequence:

>1362_bases
ATGGGACTGCCAATTGTTGCAATTATCGGTCGCCCAAATGTGGGCAAATCAACCCTGGTTAATCGTCTCGCCGGGGAACA
AACGGCGATTGTCCACGATGAACCGGGTGTGACACGCGATCGCACTTACTTACCAGCCTACTGGAGCGATCGTGAATTTC
AAGTGGTAGATACAGGCGGCTTAGTCTTTAACGATGACACAGAATTCTTGCCCCTGATTCGCCAACAAGCATTAGCTGCG
CTTCACGAAGCCAGTGCTGCTATCTTCGTTGTTAATGGTCAAACAGGCCCCAATTCGGCAGATGAAGAAATTGCCGAGTG
GTTACGCCAACAACCAGTACCAGTCTTTCTTGCAGTTAACAAATGTGAATCCCCAGACCAGGGATCGATTCAAGCCTCCG
AATTTTGGGAACTGGGACTAGGAGAACCCTACCCAATCTCTGCAATTCATGGCAACGGTACAGGCGAATTACTCGATGAA
CTGATTAAACACCTTCCTCCTGTTACAGAATTAGAAGAGAATAACGAAATCAAAATTGCCATTATTGGCAGACCAAATGT
TGGCAAATCAAGTTTATTAAACGCTTTTGCTGGCGAGGAACGGGTCATAGTTAGCCCCATTTCTGGTACAACCCGTGATG
CGATCGATACTTTTATCGAACGGGATGGGCAGAACTACCGCCTAATTGACACAGCCGGGATTCGCAAAAAGAAAAGCATT
GACTATGGTACTGAATTTTTTAGTATTAACCGTGCTTTTAAAGCGATTCGCCGCGCCGATGTAGTTTTGTTGGTTATAGA
TGCCTTGGATGGTGTCACCGAACAAGACCAAAAATTAGCTGGCAGAATTCTCGATGAAGGTAAGGCTTGTGTCGTCGTCG
TCAATAAATGGGATGCCGTCGAGAAAGACTCCTATACTATCTACGACTACGAGAAAAATCTGGAAGCGCGGCTACATTTT
ACAGAATGGGCAGACACTATCTACGTTAGTGCGGTAACAGGACAACGGGTAGAAAAGATTTTAGAGTTGGTGACTAAAGC
CAATGAAGAACACAAACGCCGCGTTAGTACATCAGTAATTAACGAAGTCCTCGAAGACGCTGTTCGTTGGCACTCTCCCC
CAACCTCTCGCGGTGGTCGCCAAGGGAGGATTTACTACGGTACACAAGTCAGCACCCAACCACCCACCATTGCTCTATTT
GTCAACGAGGCTAAACGCTTTAACGACAACTACCGTCGTTACATCGAAAGACAATTCCGCCAACAATTAGGTTTTAAGGG
GACTCCAATTCGCTTACTGTGGCGGAGTAAAAAAGTTAGGGATGTGGAAAGTGGTAGCGCTAACCGGGCAACTCGCGTTT
AA

Upstream 100 bases:

>100_bases
CAGCCTTACACCCTCACACCCAAGTCCTAGCTAAATCAAAACTTAAAGTAGCTAAAATGTAGAGATGTGATATAGTATCT
CTCTTACTTACCCTTGGTTT

Downstream 100 bases:

>100_bases
TATTTGTCAATGGTCATTAGTCATAGAAGGCGGCGGGAAACCCACTCCCTTCAAGGGGTGGGAGGGATAGCTGCCCCGCC
ACGGTTGACGGTTAACCGTT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MGLPIVAIIGRPNVGKSTLVNRLAGEQTAIVHDEPGVTRDRTYLPAYWSDREFQVVDTGGLVFNDDTEFLPLIRQQALAA
LHEASAAIFVVNGQTGPNSADEEIAEWLRQQPVPVFLAVNKCESPDQGSIQASEFWELGLGEPYPISAIHGNGTGELLDE
LIKHLPPVTELEENNEIKIAIIGRPNVGKSSLLNAFAGEERVIVSPISGTTRDAIDTFIERDGQNYRLIDTAGIRKKKSI
DYGTEFFSINRAFKAIRRADVVLLVIDALDGVTEQDQKLAGRILDEGKACVVVVNKWDAVEKDSYTIYDYEKNLEARLHF
TEWADTIYVSAVTGQRVEKILELVTKANEEHKRRVSTSVINEVLEDAVRWHSPPTSRGGRQGRIYYGTQVSTQPPTIALF
VNEAKRFNDNYRRYIERQFRQQLGFKGTPIRLLWRSKKVRDVESGSANRATRV

Sequences:

>Translated_453_residues
MGLPIVAIIGRPNVGKSTLVNRLAGEQTAIVHDEPGVTRDRTYLPAYWSDREFQVVDTGGLVFNDDTEFLPLIRQQALAA
LHEASAAIFVVNGQTGPNSADEEIAEWLRQQPVPVFLAVNKCESPDQGSIQASEFWELGLGEPYPISAIHGNGTGELLDE
LIKHLPPVTELEENNEIKIAIIGRPNVGKSSLLNAFAGEERVIVSPISGTTRDAIDTFIERDGQNYRLIDTAGIRKKKSI
DYGTEFFSINRAFKAIRRADVVLLVIDALDGVTEQDQKLAGRILDEGKACVVVVNKWDAVEKDSYTIYDYEKNLEARLHF
TEWADTIYVSAVTGQRVEKILELVTKANEEHKRRVSTSVINEVLEDAVRWHSPPTSRGGRQGRIYYGTQVSTQPPTIALF
VNEAKRFNDNYRRYIERQFRQQLGFKGTPIRLLWRSKKVRDVESGSANRATRV
>Mature_452_residues
GLPIVAIIGRPNVGKSTLVNRLAGEQTAIVHDEPGVTRDRTYLPAYWSDREFQVVDTGGLVFNDDTEFLPLIRQQALAAL
HEASAAIFVVNGQTGPNSADEEIAEWLRQQPVPVFLAVNKCESPDQGSIQASEFWELGLGEPYPISAIHGNGTGELLDEL
IKHLPPVTELEENNEIKIAIIGRPNVGKSSLLNAFAGEERVIVSPISGTTRDAIDTFIERDGQNYRLIDTAGIRKKKSID
YGTEFFSINRAFKAIRRADVVLLVIDALDGVTEQDQKLAGRILDEGKACVVVVNKWDAVEKDSYTIYDYEKNLEARLHFT
EWADTIYVSAVTGQRVEKILELVTKANEEHKRRVSTSVINEVLEDAVRWHSPPTSRGGRQGRIYYGTQVSTQPPTIALFV
NEAKRFNDNYRRYIERQFRQQLGFKGTPIRLLWRSKKVRDVESGSANRATRV

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=466, Percent_Identity=40.5579399141631, Blast_Score=326, Evalue=2e-90,
Organism=Escherichia coli, GI2367268, Length=91, Percent_Identity=48.3516483516484, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788919, Length=171, Percent_Identity=32.1637426900585, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17507259, Length=91, Percent_Identity=46.1538461538462, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323665, Length=135, Percent_Identity=38.5185185185185, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50732; Mature: 50601

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLPIVAIIGRPNVGKSTLVNRLAGEQTAIVHDEPGVTRDRTYLPAYWSDREFQVVDTGG
CCCCEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCEECCCEECCCEEEEEECCC
LVFNDDTEFLPLIRQQALAALHEASAAIFVVNGQTGPNSADEEIAEWLRQQPVPVFLAVN
EEECCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEE
KCESPDQGSIQASEFWELGLGEPYPISAIHGNGTGELLDELIKHLPPVTELEENNEIKIA
CCCCCCCCCEEHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEE
IIGRPNVGKSSLLNAFAGEERVIVSPISGTTRDAIDTFIERDGQNYRLIDTAGIRKKKSI
EEECCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCC
DYGTEFFSINRAFKAIRRADVVLLVIDALDGVTEQDQKLAGRILDEGKACVVVVNKWDAV
CCCHHHHHHHHHHHHHHHCCEEEEEEEHHCCCCHHHHHHHHHHHCCCCEEEEEEECCCCC
EKDSYTIYDYEKNLEARLHFTEWADTIYVSAVTGQRVEKILELVTKANEEHKRRVSTSVI
CCCCEEEEEECCCCEEEEEEEECCCEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHH
NEVLEDAVRWHSPPTSRGGRQGRIYYGTQVSTQPPTIALFVNEAKRFNDNYRRYIERQFR
HHHHHHHHHHCCCCCCCCCCCCEEEECCEECCCCCEEEEEECCHHHCCHHHHHHHHHHHH
QQLGFKGTPIRLLWRSKKVRDVESGSANRATRV
HHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GLPIVAIIGRPNVGKSTLVNRLAGEQTAIVHDEPGVTRDRTYLPAYWSDREFQVVDTGG
CCCEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCEECCCEECCCEEEEEECCC
LVFNDDTEFLPLIRQQALAALHEASAAIFVVNGQTGPNSADEEIAEWLRQQPVPVFLAVN
EEECCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEE
KCESPDQGSIQASEFWELGLGEPYPISAIHGNGTGELLDELIKHLPPVTELEENNEIKIA
CCCCCCCCCEEHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEE
IIGRPNVGKSSLLNAFAGEERVIVSPISGTTRDAIDTFIERDGQNYRLIDTAGIRKKKSI
EEECCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCC
DYGTEFFSINRAFKAIRRADVVLLVIDALDGVTEQDQKLAGRILDEGKACVVVVNKWDAV
CCCHHHHHHHHHHHHHHHCCEEEEEEEHHCCCCHHHHHHHHHHHCCCCEEEEEEECCCCC
EKDSYTIYDYEKNLEARLHFTEWADTIYVSAVTGQRVEKILELVTKANEEHKRRVSTSVI
CCCCEEEEEECCCCEEEEEEEECCCEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHH
NEVLEDAVRWHSPPTSRGGRQGRIYYGTQVSTQPPTIALFVNEAKRFNDNYRRYIERQFR
HHHHHHHHHHCCCCCCCCCCCCEEEECCEECCCCCEEEEEECCHHHCCHHHHHHHHHHHH
QQLGFKGTPIRLLWRSKKVRDVESGSANRATRV
HHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA