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The map label for this gene is macB [H]

Identifier: 17227942

GI number: 17227942

Start: 528893

End: 530164

Strand: Direct

Name: macB [H]

Synonym: alr0446

Alternate gene names: 17227942

Gene position: 528893-530164 (Clockwise)

Preceding gene: 17227941

Following gene: 17227943

Centisome position: 8.25

GC content: 43.4

Gene sequence:

>1272_bases
ATGTTTAAGGGTTTTTATAAAAAAAATAATACTCGTACCGTTCCATTTTTAGAAATATTGTTAATGGCGGCTGAGACCCT
GTGGAGTAATAAATTACGCACAGGGTTAACTATGTTGGGTGTAATTATCGGTATTGCTTCAGTTATTGCTATCACTTCCG
TAGGTCAGGGGGTGCAGAAGAGTGTGGAGCAGCAAATTCAAGCTTTGGGAACAGATGTTATACAAATTTTGGCGGGTGCG
CCTAGAAGTGGCAATGTCCGACAGGGTTTAGGTTCTACCAGTACATTAACTTGGGAAGATGCAAAAGCGATCGCCCAACA
AGCACCCTCAGCTGAGATTGTTTCTGCTTACCTCCAGCGCAACGCTCAAGTTGTTTATGGTGGGGAGAACACTTCTACCA
CAATTTACGGCACAGATTTAAACTACCCAGAAGCGAGAAATACTCACCCCCAAGAAGGAAGATATTTTACTCAACAAGAA
TTGGATTCATCCGCACAAGTTGCAGTGATTGGGCCGACAGTCCAGAGAACACTGTTTGGCCAGGGTGGTACACCCATAGG
TGAGAAAATTCGTATTCAAGGAGAGGCTTATGATGTGATTGGAATTACGGAACCAAAGGGTTCTCAAGGCCCGATGGATA
GAGATGACCAAATATTTATTCCTCTGACAAGTATGTCAAAGCGGCTGGTGGGAAACAATGCCCTGACTGGCGTTTCGGTA
AGTGGCATTTTAGTAAAATCTAGTAATCAGGAACAGTTAGAGGCGGCACAATTTCAAGTTACAAATATCTTACGTTTGCG
TCATAATATCTATCCGCCACAAGCCGATGATTTCCGCCTGACTAACCAAGCCGACATTGTGAGTACCTTCACAAACGTAG
TGGGTTTATTTACGATTATGGTAGTGGCGATCGCCGGCATTTCCCTAGTTGTTGGTGGTATAGGCATTGCCAATATTATG
CTAGTCTCCGTTGTGGAACGAACACGGGAAATCGGCATTCGTAAAGCCGTAGGAGCCACAAATTCAGCTATTCTTAATCA
GTTTTTAGCCGAGGCGATCGTCATTTCTATTGTTGGCGGCGGCATAGGTATAGGCGGGGGAATTTTAATTGCTTTTGCTT
CTGCTACTATATTCAAATTTCCCTTTGTAATATCTATTATTTCCATTATTGTTGGCTTTGGACTCTCACTCACCGTTGGC
TTAATTGCCGGAGTGATTCCCGCTAGAAATGCCTCTAAACTAGACCCTATTACTGCATTACGTAGTGATTAG

Upstream 100 bases:

>100_bases
CGTTCCCGTAATGCTGCGCCTTAAGGCAATTCATGAGAGACGTTGTATACAACGTCCGTAAATTATTCCTTCCCCAGTCC
CCAATCGCCAATCCCCATTT

Downstream 100 bases:

>100_bases
GAAACACCAAAAAATAAATTATCCCAAATTGACGGTTAGTAGCATCAGTATGAATAATTTGTGGTAAAGCTAAGTATCCT
CGCACTGACGCACCCTACAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MFKGFYKKNNTRTVPFLEILLMAAETLWSNKLRTGLTMLGVIIGIASVIAITSVGQGVQKSVEQQIQALGTDVIQILAGA
PRSGNVRQGLGSTSTLTWEDAKAIAQQAPSAEIVSAYLQRNAQVVYGGENTSTTIYGTDLNYPEARNTHPQEGRYFTQQE
LDSSAQVAVIGPTVQRTLFGQGGTPIGEKIRIQGEAYDVIGITEPKGSQGPMDRDDQIFIPLTSMSKRLVGNNALTGVSV
SGILVKSSNQEQLEAAQFQVTNILRLRHNIYPPQADDFRLTNQADIVSTFTNVVGLFTIMVVAIAGISLVVGGIGIANIM
LVSVVERTREIGIRKAVGATNSAILNQFLAEAIVISIVGGGIGIGGGILIAFASATIFKFPFVISIISIIVGFGLSLTVG
LIAGVIPARNASKLDPITALRSD

Sequences:

>Translated_423_residues
MFKGFYKKNNTRTVPFLEILLMAAETLWSNKLRTGLTMLGVIIGIASVIAITSVGQGVQKSVEQQIQALGTDVIQILAGA
PRSGNVRQGLGSTSTLTWEDAKAIAQQAPSAEIVSAYLQRNAQVVYGGENTSTTIYGTDLNYPEARNTHPQEGRYFTQQE
LDSSAQVAVIGPTVQRTLFGQGGTPIGEKIRIQGEAYDVIGITEPKGSQGPMDRDDQIFIPLTSMSKRLVGNNALTGVSV
SGILVKSSNQEQLEAAQFQVTNILRLRHNIYPPQADDFRLTNQADIVSTFTNVVGLFTIMVVAIAGISLVVGGIGIANIM
LVSVVERTREIGIRKAVGATNSAILNQFLAEAIVISIVGGGIGIGGGILIAFASATIFKFPFVISIISIIVGFGLSLTVG
LIAGVIPARNASKLDPITALRSD
>Mature_423_residues
MFKGFYKKNNTRTVPFLEILLMAAETLWSNKLRTGLTMLGVIIGIASVIAITSVGQGVQKSVEQQIQALGTDVIQILAGA
PRSGNVRQGLGSTSTLTWEDAKAIAQQAPSAEIVSAYLQRNAQVVYGGENTSTTIYGTDLNYPEARNTHPQEGRYFTQQE
LDSSAQVAVIGPTVQRTLFGQGGTPIGEKIRIQGEAYDVIGITEPKGSQGPMDRDDQIFIPLTSMSKRLVGNNALTGVSV
SGILVKSSNQEQLEAAQFQVTNILRLRHNIYPPQADDFRLTNQADIVSTFTNVVGLFTIMVVAIAGISLVVGGIGIANIM
LVSVVERTREIGIRKAVGATNSAILNQFLAEAIVISIVGGGIGIGGGILIAFASATIFKFPFVISIISIIVGFGLSLTVG
LIAGVIPARNASKLDPITALRSD

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=406, Percent_Identity=35.9605911330049, Blast_Score=203, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44829; Mature: 44829

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKGFYKKNNTRTVPFLEILLMAAETLWSNKLRTGLTMLGVIIGIASVIAITSVGQGVQK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
SVEQQIQALGTDVIQILAGAPRSGNVRQGLGSTSTLTWEDAKAIAQQAPSAEIVSAYLQR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCEEEHHHHHHHHHHCCCHHHHHHHHHC
NAQVVYGGENTSTTIYGTDLNYPEARNTHPQEGRYFTQQELDSSAQVAVIGPTVQRTLFG
CCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCEECHHHCCCCCEEEEECCHHHHHHCC
QGGTPIGEKIRIQGEAYDVIGITEPKGSQGPMDRDDQIFIPLTSMSKRLVGNNALTGVSV
CCCCCCCCEEEEECCEEEEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCEEE
SGILVKSSNQEQLEAAQFQVTNILRLRHNIYPPQADDFRLTNQADIVSTFTNVVGLFTIM
EEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHH
VVAIAGISLVVGGIGIANIMLVSVVERTREIGIRKAVGATNSAILNQFLAEAIVISIVGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
GIGIGGGILIAFASATIFKFPFVISIISIIVGFGLSLTVGLIAGVIPARNASKLDPITAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHH
RSD
CCC
>Mature Secondary Structure
MFKGFYKKNNTRTVPFLEILLMAAETLWSNKLRTGLTMLGVIIGIASVIAITSVGQGVQK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
SVEQQIQALGTDVIQILAGAPRSGNVRQGLGSTSTLTWEDAKAIAQQAPSAEIVSAYLQR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCEEEHHHHHHHHHHCCCHHHHHHHHHC
NAQVVYGGENTSTTIYGTDLNYPEARNTHPQEGRYFTQQELDSSAQVAVIGPTVQRTLFG
CCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCEECHHHCCCCCEEEEECCHHHHHHCC
QGGTPIGEKIRIQGEAYDVIGITEPKGSQGPMDRDDQIFIPLTSMSKRLVGNNALTGVSV
CCCCCCCCEEEEECCEEEEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCEEE
SGILVKSSNQEQLEAAQFQVTNILRLRHNIYPPQADDFRLTNQADIVSTFTNVVGLFTIM
EEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHH
VVAIAGISLVVGGIGIANIMLVSVVERTREIGIRKAVGATNSAILNQFLAEAIVISIVGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
GIGIGGGILIAFASATIFKFPFVISIISIIVGFGLSLTVGLIAGVIPARNASKLDPITAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHH
RSD
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA