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The map label for this gene is yxnA [H]

Identifier: 17227926

GI number: 17227926

Start: 507978

End: 508844

Strand: Direct

Name: yxnA [H]

Synonym: alr0430

Alternate gene names: 17227926

Gene position: 507978-508844 (Clockwise)

Preceding gene: 17227925

Following gene: 17227927

Centisome position: 7.92

GC content: 44.18

Gene sequence:

>867_bases
GTGAGAGAGATTACAGACTTTGGTGGTGAAGCAATTGCTGTAGTCGCTAACGTGGAAAAATTTGAGCAAGTTAAGGCGAT
CGCTGATAAAACTGTAGAGGTATATGGCAGACTTGATACTTGGGTACACGTTTCAGCTATTGGACTGTTTGCCAATTTCG
ATGATATTACACCAGAAGAATTTAAACACGTCATCGATGTCAACCTGATGGGGCAAGTATACGGTGCGATGGCTGCACTC
CCCCATTTGAAGCGTGAGGGACGGGGTGCATTGATTCACATATCTTCAATGGAAGCTAGGCGATCTCTACCATACCAAAG
TGCTTATTCCTCATCAAAACATGGGGTAGATGGGTTTATTGATGCTATGCGCCTGGAATTGATCCATGATAAATGGCCGA
TTAGCGTCACTAGTATTAAACCAGCCGTCATCAACACCCCTTTCTGGAATAATGGTTTAACAAAGTTAGGAGTCAAACCT
TCAGGAACACCGCCATACTATGATCCCAGGTTAGTAGCTAACGCCATTCTCTATGCAGCCGAACATCCAACTCGTGATTT
ATTAGTTGGAGATGTAGCTAAGATACTGGATTTATTACATCGCATCTCGCCAGCGTTAACAGATTCATTGTTACTCTTGG
TTGGCTTCCAATCTCAACATATTTCTGGCGAACCCAAATCTGAAGCTGGGGCAAATAACTTTTACCAACCAGTCCCAGAA
CACGACAGAGTAGATGGCGACTACAGCAACTTAGTCATCCCCAGCATTTCCGATTTTCTAGAACAGAATCCACCATTACA
ATGGGGTGCGATCGCTGCCGGTACAGTATTAGCTTTACTCACAGCCCAAGCTCTTAAGCGCAATTGA

Upstream 100 bases:

>100_bases
GGCTGCTAGTGGGATTGGACGAGAAGCGGCTATTCGCTTTGCTCAACGTGGGGCTAAGGTTGTTGTTTCTGCCCGTAGCC
AATCAGGGCTAGAGTCTTTG

Downstream 100 bases:

>100_bases
ATAGAAAAATCATTCTAGATTTTGGATGGAAATAGCCTTGATTTCTGTACTTACATATATCTTTAACAAGTCAATGATCA
AGTTCTATCTTTAGATTTAT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MREITDFGGEAIAVVANVEKFEQVKAIADKTVEVYGRLDTWVHVSAIGLFANFDDITPEEFKHVIDVNLMGQVYGAMAAL
PHLKREGRGALIHISSMEARRSLPYQSAYSSSKHGVDGFIDAMRLELIHDKWPISVTSIKPAVINTPFWNNGLTKLGVKP
SGTPPYYDPRLVANAILYAAEHPTRDLLVGDVAKILDLLHRISPALTDSLLLLVGFQSQHISGEPKSEAGANNFYQPVPE
HDRVDGDYSNLVIPSISDFLEQNPPLQWGAIAAGTVLALLTAQALKRN

Sequences:

>Translated_288_residues
MREITDFGGEAIAVVANVEKFEQVKAIADKTVEVYGRLDTWVHVSAIGLFANFDDITPEEFKHVIDVNLMGQVYGAMAAL
PHLKREGRGALIHISSMEARRSLPYQSAYSSSKHGVDGFIDAMRLELIHDKWPISVTSIKPAVINTPFWNNGLTKLGVKP
SGTPPYYDPRLVANAILYAAEHPTRDLLVGDVAKILDLLHRISPALTDSLLLLVGFQSQHISGEPKSEAGANNFYQPVPE
HDRVDGDYSNLVIPSISDFLEQNPPLQWGAIAAGTVLALLTAQALKRN
>Mature_288_residues
MREITDFGGEAIAVVANVEKFEQVKAIADKTVEVYGRLDTWVHVSAIGLFANFDDITPEEFKHVIDVNLMGQVYGAMAAL
PHLKREGRGALIHISSMEARRSLPYQSAYSSSKHGVDGFIDAMRLELIHDKWPISVTSIKPAVINTPFWNNGLTKLGVKP
SGTPPYYDPRLVANAILYAAEHPTRDLLVGDVAKILDLLHRISPALTDSLLLLVGFQSQHISGEPKSEAGANNFYQPVPE
HDRVDGDYSNLVIPSISDFLEQNPPLQWGAIAAGTVLALLTAQALKRN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=29.5336787564767, Blast_Score=88, Evalue=8e-18,
Organism=Escherichia coli, GI1788459, Length=164, Percent_Identity=29.2682926829268, Blast_Score=71, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6324126, Length=154, Percent_Identity=29.8701298701299, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21358495, Length=182, Percent_Identity=29.1208791208791, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24649181, Length=190, Percent_Identity=26.3157894736842, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31558; Mature: 31558

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00061 ADH_SHORT ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREITDFGGEAIAVVANVEKFEQVKAIADKTVEVYGRLDTWVHVSAIGLFANFDDITPEE
CCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHECCCCCCCHHH
FKHVIDVNLMGQVYGAMAALPHLKREGRGALIHISSMEARRSLPYQSAYSSSKHGVDGFI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHCCCCHHHHCCCCCCHHHHH
DAMRLELIHDKWPISVTSIKPAVINTPFWNNGLTKLGVKPSGTPPYYDPRLVANAILYAA
HHHHHHHHHCCCCEEEEECCCEEECCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHC
EHPTRDLLVGDVAKILDLLHRISPALTDSLLLLVGFQSQHISGEPKSEAGANNFYQPVPE
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHEECCCHHCCCCCCCCCCCCCCCCCCCCC
HDRVDGDYSNLVIPSISDFLEQNPPLQWGAIAAGTVLALLTAQALKRN
CCCCCCCCCCEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MREITDFGGEAIAVVANVEKFEQVKAIADKTVEVYGRLDTWVHVSAIGLFANFDDITPEE
CCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHECCCCCCCHHH
FKHVIDVNLMGQVYGAMAALPHLKREGRGALIHISSMEARRSLPYQSAYSSSKHGVDGFI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHCCCCHHHHCCCCCCHHHHH
DAMRLELIHDKWPISVTSIKPAVINTPFWNNGLTKLGVKPSGTPPYYDPRLVANAILYAA
HHHHHHHHHCCCCEEEEECCCEEECCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHC
EHPTRDLLVGDVAKILDLLHRISPALTDSLLLLVGFQSQHISGEPKSEAGANNFYQPVPE
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHEECCCHHCCCCCCCCCCCCCCCCCCCCC
HDRVDGDYSNLVIPSISDFLEQNPPLQWGAIAAGTVLALLTAQALKRN
CCCCCCCCCCEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]