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The map label for this gene is putA [H]

Identifier: 172087817

GI number: 172087817

Start: 933762

End: 936938

Strand: Reverse

Name: putA [H]

Synonym: VF_A0832

Alternate gene names: 172087817

Gene position: 936938-933762 (Counterclockwise)

Preceding gene: 59714016

Following gene: 59714013

Centisome position: 70.43

GC content: 41.11

Gene sequence:

>3177_bases
ATGTCAGATAAACAAGAGGAAACAGGTATGTTTCAAGCGAAAGAAGTATTGTCCTCATCTATAATTGAGCAACCGTTAGA
ATCATTATGGTCTGCTATTTCTCCTCTCTACATGGTTGATGAAGCCAAATGGCTGCACCAGCTATTACCATTAGCTAAAC
CAACAGACCGTGAAGCCGTTATGATGGAAAAACACGCAGCGATACTGATACAGCGTGTTCGTGATGACAAAAAAGCGGTG
CAAATGATAGATGCACTTTTGCTCGAGTACAGTTTAGATACTAAGGAAGGCATATTATTAATGTGTCTTGCTGAGGCGCT
AATGCGTATTCCTGATGCTGAAACAGCGGATGCATTAATTCGAGATAAATTGAGTGTTGCAGATTGGAAGTCTCATTTAA
AAAACTCAGATTCTACTTTTGTTAATGCTTCTACGTGGGGGCTTCTTTTAACGGGTAAAGTTGTATCTATGGATGTCAAA
GCTGATGGTTCTCCATCTAATGCCTTGAGTCGACTCGTTAATAAATTTTCAGAGCCTGTGATCCGTCAAGCAATGAATCA
AGCCATGAAAATAATGGGGCATCAGTTTGTGCTTGGGCGAACCATAGAAGAAGCTCAGAAAAAAGGATTATCGATGCGAG
AGAAAGGGTATACCTATTCTTTCGATATGCTAGGTGAAGCGGCATTAACGCAAACGGATGCTCATAAGTATTTTAAAGAT
TACATCATGGCTATTGAAAGCGTTGGTCGTGCTGCAAGTATTGCGAATTCTCCAGAACCAACGGTTTCAATCAAATTGTC
AGCATTGCATCCTCGTTATGAAGTTGCAAATAAAGAACGAGTCATGAATGAGATGTACCAATCTGTGCTGCAATTATTAG
AACGTGCACGAGAATTGGATGTGGGTATTACTATCGATGCAGAAGAAATGGATCGTTTAGAGTTATCTCTTGAGCTTTTT
GAAAAGTTATATCGTAGCGACATAGTAAAAGGGTGGGGAAAGTTCGGACTGGTTGTTCAAGCTTATTCGAAACGAGCGTT
GCCGGTTTTAGTATGGTTAACGGCGTTATCAAAAGAACAAGAAGACCTCATTCCACTTAGGTTAGTAAAAGGTGCCTATT
GGGATACGGAATTAAAATTATCTCAACAGTTTGGATTTGCACGATATCCTGTCTTTACTCGTAAAGAGGCCACTGACGTA
TCTTATTTAGCTTGCGCTCGTTACTTATTAAGCGAGCATGTAAAAGGTAAGATTTTTCCACAGTTTGCTAGTCATAATGC
ACACACGGTTGCCGCCATTGCCTCTATGGCAACACATGATGAATTCGAATTTCAACGGCTGCATGGTATGGGAGATGCAC
TTTATGAACACGCTATGGACATGTTTAACCGCAGTGTTCGTATTTATGCACCAGTAGGAAGCCATAAAGATTTATTGCCA
TACCTCGTAAGACGTTTATTAGAGAATGGAGCTAACAGCTCTTTTGTTCATCGTTTGGTTGATGCGAATTGTCCGATTGA
AAGCTTAACGGTTCACCCTGTTGATTCTTTATTAGCGTGTCCATCATTAGAGAATCAATTAATTCCGCTACCGCCATATA
TTTTCTCTGATCGTAAAAATTCATACAGCATTAACTTAGATGTTGAAAGTGAAGCCCATCCATTTGAACGTCAAGTAAAA
GAACAAATGAAAACGTATTGGCAAGGTGGTCCAATCGTGAGCAACATCCGAGATTACGAAAGCATGATCAAGGAACATGG
TTCTGCACTTCATGTTATTAACTCTCCTTATGATCGTGGAAATGACGTTGGCTCATTGGTCTGGAGTTCACAAGAGCAAG
TATCCAATGCGTTAGATATTGCTCATGATTACTTTCCTATTTGGCAGCAAACGCCAGTGGCAGAGCGAGCTGATTACCTT
GAAGCTCTGGCAGATAAGTTAGAGATGAACATGCCTGAACTTGTCGCTTTATGTCATAAAGAAGCAGGAAAAACGATTCA
TGATAGTATTGATGAAGTGCGTGAGGCGGTGGATTTTTGCCGTTATTATGCTGTTCAAGCTAAATTGAATTTTACAACGG
CAGAAACCATCGTTGGTTTTGATGATATTTCTCGCCAAATTGAACGTCAAGGGCGAGGTGTTTTTGTTTGTATTAGCCCT
TGGAATTTCCCTCTTGCCATTTTCTTAGGTCAAGTAACAGCAGCATTAGTTGCTGGTAATACGGTTATAGCTAAGCCAGC
AGAACAAACGTCATTGATTGCAGTTCGAGCTATTGAATTGTTGTTAGAGACGGGAATAGCTCCGCAAGCGGTACATTTAT
TACCGGGTGATGGGAAAACCGTCGGTGCTCCATTGACCTCTGATCATCGTGTGGCTGGTGTTGCTTTTACAGGTTCAACT
GAAACTGCACAACTTATCAATCGCACCTTAGCGAACCGGTCAATTGAGGGGGAAGGGGTTTCTCCTGTGCCTTTTATTGC
TGAAACGGGTGGCCAAAATGCCATGATAGTAGACAGTACCGCATTACCTGAACAAGTGGTACGAGATGTAATACGTTCAG
CGTTTGCTTCTGCCGGTCAGCGTTGTTCAGCTTTACGTGTGTTGTTTGTTCAACAAGATATTGCCGATAGAATTATCAAT
CTTATTAAAGGGGCAATGGCTGAGCTAAGTGTCGGATTGCCTGAGTTACACTGTACTGATGTTGGGCCAGTTATTGATGT
GCGTGCGAAAGATAAATTGATGGCGCACATTGAAAGAATGACAAAAGAAGGTGTACTGGTTGCACAAGCTGAACTACCTA
ATTGGTCTGAAAAGGGCGATTTTGTTCCACCAAGTGCGTTTGAAATTGAATCAATTAAACAATTAGAAAATGAACAATTT
GGTCCGATTCTTCATATTGTTCGTTTTAAAGCCAGTGATATAGATAAGGTCATTTCTGAGATTAATTCGACCGGATTTGG
GTTAACCATGGGGGTCCATAGCCGTAATGAAGTGACATACACACGAATAGAGAAAAACATCAAAGTGGGTAATTGCTATA
TCAATCGTGATCAAGTTGGTGCAGTCGTTGGTGTTCAACCGTTTGGTGGGCAAGGGTTATCGGGGACTGGACCTAAAGCG
GGTGGGCCTCGTTATTTAATTCGTTATACAAAAGCAAATACAACGACTTCAAAATGA

Upstream 100 bases:

>100_bases
GGTTTTGACAAGTATTCAGACTAAATAGAAAATAGAATCTTTCGCAATAAACTCTAATAATAACTAGCTTAGCTATGAGG
CTCTGTCTTTATAGTTAATC

Downstream 100 bases:

>100_bases
GAAAGGAGATCTCCATGACTAAAATGACACAAATCATTGATTCAGTGCTTTCTCAAGGATTGACTGAGTGGCAATCTGAG
TCAGCATCATTTCGAATTGA

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1058; Mature: 1057

Protein sequence:

>1058_residues
MSDKQEETGMFQAKEVLSSSIIEQPLESLWSAISPLYMVDEAKWLHQLLPLAKPTDREAVMMEKHAAILIQRVRDDKKAV
QMIDALLLEYSLDTKEGILLMCLAEALMRIPDAETADALIRDKLSVADWKSHLKNSDSTFVNASTWGLLLTGKVVSMDVK
ADGSPSNALSRLVNKFSEPVIRQAMNQAMKIMGHQFVLGRTIEEAQKKGLSMREKGYTYSFDMLGEAALTQTDAHKYFKD
YIMAIESVGRAASIANSPEPTVSIKLSALHPRYEVANKERVMNEMYQSVLQLLERARELDVGITIDAEEMDRLELSLELF
EKLYRSDIVKGWGKFGLVVQAYSKRALPVLVWLTALSKEQEDLIPLRLVKGAYWDTELKLSQQFGFARYPVFTRKEATDV
SYLACARYLLSEHVKGKIFPQFASHNAHTVAAIASMATHDEFEFQRLHGMGDALYEHAMDMFNRSVRIYAPVGSHKDLLP
YLVRRLLENGANSSFVHRLVDANCPIESLTVHPVDSLLACPSLENQLIPLPPYIFSDRKNSYSINLDVESEAHPFERQVK
EQMKTYWQGGPIVSNIRDYESMIKEHGSALHVINSPYDRGNDVGSLVWSSQEQVSNALDIAHDYFPIWQQTPVAERADYL
EALADKLEMNMPELVALCHKEAGKTIHDSIDEVREAVDFCRYYAVQAKLNFTTAETIVGFDDISRQIERQGRGVFVCISP
WNFPLAIFLGQVTAALVAGNTVIAKPAEQTSLIAVRAIELLLETGIAPQAVHLLPGDGKTVGAPLTSDHRVAGVAFTGST
ETAQLINRTLANRSIEGEGVSPVPFIAETGGQNAMIVDSTALPEQVVRDVIRSAFASAGQRCSALRVLFVQQDIADRIIN
LIKGAMAELSVGLPELHCTDVGPVIDVRAKDKLMAHIERMTKEGVLVAQAELPNWSEKGDFVPPSAFEIESIKQLENEQF
GPILHIVRFKASDIDKVISEINSTGFGLTMGVHSRNEVTYTRIEKNIKVGNCYINRDQVGAVVGVQPFGGQGLSGTGPKA
GGPRYLIRYTKANTTTSK

Sequences:

>Translated_1058_residues
MSDKQEETGMFQAKEVLSSSIIEQPLESLWSAISPLYMVDEAKWLHQLLPLAKPTDREAVMMEKHAAILIQRVRDDKKAV
QMIDALLLEYSLDTKEGILLMCLAEALMRIPDAETADALIRDKLSVADWKSHLKNSDSTFVNASTWGLLLTGKVVSMDVK
ADGSPSNALSRLVNKFSEPVIRQAMNQAMKIMGHQFVLGRTIEEAQKKGLSMREKGYTYSFDMLGEAALTQTDAHKYFKD
YIMAIESVGRAASIANSPEPTVSIKLSALHPRYEVANKERVMNEMYQSVLQLLERARELDVGITIDAEEMDRLELSLELF
EKLYRSDIVKGWGKFGLVVQAYSKRALPVLVWLTALSKEQEDLIPLRLVKGAYWDTELKLSQQFGFARYPVFTRKEATDV
SYLACARYLLSEHVKGKIFPQFASHNAHTVAAIASMATHDEFEFQRLHGMGDALYEHAMDMFNRSVRIYAPVGSHKDLLP
YLVRRLLENGANSSFVHRLVDANCPIESLTVHPVDSLLACPSLENQLIPLPPYIFSDRKNSYSINLDVESEAHPFERQVK
EQMKTYWQGGPIVSNIRDYESMIKEHGSALHVINSPYDRGNDVGSLVWSSQEQVSNALDIAHDYFPIWQQTPVAERADYL
EALADKLEMNMPELVALCHKEAGKTIHDSIDEVREAVDFCRYYAVQAKLNFTTAETIVGFDDISRQIERQGRGVFVCISP
WNFPLAIFLGQVTAALVAGNTVIAKPAEQTSLIAVRAIELLLETGIAPQAVHLLPGDGKTVGAPLTSDHRVAGVAFTGST
ETAQLINRTLANRSIEGEGVSPVPFIAETGGQNAMIVDSTALPEQVVRDVIRSAFASAGQRCSALRVLFVQQDIADRIIN
LIKGAMAELSVGLPELHCTDVGPVIDVRAKDKLMAHIERMTKEGVLVAQAELPNWSEKGDFVPPSAFEIESIKQLENEQF
GPILHIVRFKASDIDKVISEINSTGFGLTMGVHSRNEVTYTRIEKNIKVGNCYINRDQVGAVVGVQPFGGQGLSGTGPKA
GGPRYLIRYTKANTTTSK
>Mature_1057_residues
SDKQEETGMFQAKEVLSSSIIEQPLESLWSAISPLYMVDEAKWLHQLLPLAKPTDREAVMMEKHAAILIQRVRDDKKAVQ
MIDALLLEYSLDTKEGILLMCLAEALMRIPDAETADALIRDKLSVADWKSHLKNSDSTFVNASTWGLLLTGKVVSMDVKA
DGSPSNALSRLVNKFSEPVIRQAMNQAMKIMGHQFVLGRTIEEAQKKGLSMREKGYTYSFDMLGEAALTQTDAHKYFKDY
IMAIESVGRAASIANSPEPTVSIKLSALHPRYEVANKERVMNEMYQSVLQLLERARELDVGITIDAEEMDRLELSLELFE
KLYRSDIVKGWGKFGLVVQAYSKRALPVLVWLTALSKEQEDLIPLRLVKGAYWDTELKLSQQFGFARYPVFTRKEATDVS
YLACARYLLSEHVKGKIFPQFASHNAHTVAAIASMATHDEFEFQRLHGMGDALYEHAMDMFNRSVRIYAPVGSHKDLLPY
LVRRLLENGANSSFVHRLVDANCPIESLTVHPVDSLLACPSLENQLIPLPPYIFSDRKNSYSINLDVESEAHPFERQVKE
QMKTYWQGGPIVSNIRDYESMIKEHGSALHVINSPYDRGNDVGSLVWSSQEQVSNALDIAHDYFPIWQQTPVAERADYLE
ALADKLEMNMPELVALCHKEAGKTIHDSIDEVREAVDFCRYYAVQAKLNFTTAETIVGFDDISRQIERQGRGVFVCISPW
NFPLAIFLGQVTAALVAGNTVIAKPAEQTSLIAVRAIELLLETGIAPQAVHLLPGDGKTVGAPLTSDHRVAGVAFTGSTE
TAQLINRTLANRSIEGEGVSPVPFIAETGGQNAMIVDSTALPEQVVRDVIRSAFASAGQRCSALRVLFVQQDIADRIINL
IKGAMAELSVGLPELHCTDVGPVIDVRAKDKLMAHIERMTKEGVLVAQAELPNWSEKGDFVPPSAFEIESIKQLENEQFG
PILHIVRFKASDIDKVISEINSTGFGLTMGVHSRNEVTYTRIEKNIKVGNCYINRDQVGAVVGVQPFGGQGLSGTGPKAG
GPRYLIRYTKANTTTSK

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI153266822, Length=434, Percent_Identity=30.8755760368664, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI21361176, Length=455, Percent_Identity=30.989010989011, Blast_Score=181, Evalue=4e-45,
Organism=Homo sapiens, GI25777736, Length=465, Percent_Identity=29.4623655913978, Blast_Score=174, Evalue=4e-43,
Organism=Homo sapiens, GI25777734, Length=465, Percent_Identity=29.4623655913978, Blast_Score=174, Evalue=4e-43,
Organism=Homo sapiens, GI238859541, Length=465, Percent_Identity=29.4623655913978, Blast_Score=173, Evalue=1e-42,
Organism=Homo sapiens, GI12007648, Length=466, Percent_Identity=29.3991416309013, Blast_Score=170, Evalue=6e-42,
Organism=Homo sapiens, GI25777724, Length=452, Percent_Identity=28.7610619469027, Blast_Score=165, Evalue=2e-40,
Organism=Homo sapiens, GI25777728, Length=430, Percent_Identity=29.5348837209302, Blast_Score=159, Evalue=2e-38,
Organism=Homo sapiens, GI238814322, Length=440, Percent_Identity=28.6363636363636, Blast_Score=157, Evalue=5e-38,
Organism=Homo sapiens, GI25777732, Length=456, Percent_Identity=29.3859649122807, Blast_Score=157, Evalue=6e-38,
Organism=Homo sapiens, GI21614513, Length=437, Percent_Identity=29.7482837528604, Blast_Score=157, Evalue=6e-38,
Organism=Homo sapiens, GI25777730, Length=469, Percent_Identity=29.2110874200426, Blast_Score=153, Evalue=7e-37,
Organism=Homo sapiens, GI188035924, Length=446, Percent_Identity=27.3542600896861, Blast_Score=137, Evalue=5e-32,
Organism=Homo sapiens, GI310128093, Length=431, Percent_Identity=27.6102088167053, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI310128103, Length=431, Percent_Identity=27.6102088167053, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI25952152, Length=460, Percent_Identity=27.8260869565217, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI115387104, Length=459, Percent_Identity=26.3616557734205, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI4507229, Length=435, Percent_Identity=27.1264367816092, Blast_Score=123, Evalue=1e-27,
Organism=Homo sapiens, GI310128091, Length=418, Percent_Identity=27.9904306220096, Blast_Score=120, Evalue=5e-27,
Organism=Homo sapiens, GI25777726, Length=453, Percent_Identity=25.8278145695364, Blast_Score=116, Evalue=1e-25,
Organism=Homo sapiens, GI25777721, Length=448, Percent_Identity=26.1160714285714, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI11095441, Length=422, Percent_Identity=25.3554502369668, Blast_Score=112, Evalue=3e-24,
Organism=Homo sapiens, GI310128089, Length=327, Percent_Identity=27.217125382263, Blast_Score=96, Evalue=3e-19,
Organism=Homo sapiens, GI310128087, Length=257, Percent_Identity=28.7937743190661, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI301500698, Length=301, Percent_Identity=27.2425249169435, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI310128095, Length=313, Percent_Identity=27.7955271565495, Blast_Score=91, Evalue=6e-18,
Organism=Homo sapiens, GI4502043, Length=341, Percent_Identity=25.5131964809384, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI238814371, Length=341, Percent_Identity=25.5131964809384, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI71773324, Length=341, Percent_Identity=25.5131964809384, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI206597441, Length=445, Percent_Identity=25.6179775280899, Blast_Score=85, Evalue=4e-16,
Organism=Homo sapiens, GI206597439, Length=445, Percent_Identity=25.6179775280899, Blast_Score=85, Evalue=4e-16,
Organism=Homo sapiens, GI22907049, Length=445, Percent_Identity=25.6179775280899, Blast_Score=85, Evalue=4e-16,
Organism=Homo sapiens, GI310128101, Length=198, Percent_Identity=27.7777777777778, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI310128099, Length=198, Percent_Identity=27.7777777777778, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI310128097, Length=261, Percent_Identity=27.9693486590038, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI73466520, Length=337, Percent_Identity=24.3323442136499, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI4557303, Length=337, Percent_Identity=24.3323442136499, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI73695881, Length=349, Percent_Identity=23.7822349570201, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI73695879, Length=349, Percent_Identity=23.7822349570201, Blast_Score=79, Evalue=3e-14,
Organism=Escherichia coli, GI1787250, Length=1044, Percent_Identity=48.1800766283525, Blast_Score=888, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=477, Percent_Identity=29.559748427673, Blast_Score=163, Evalue=6e-41,
Organism=Escherichia coli, GI1787684, Length=441, Percent_Identity=28.7981859410431, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI1787715, Length=423, Percent_Identity=30.7328605200946, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI87081896, Length=460, Percent_Identity=28.9130434782609, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI1788042, Length=447, Percent_Identity=27.7404921700224, Blast_Score=142, Evalue=8e-35,
Organism=Escherichia coli, GI1787558, Length=420, Percent_Identity=27.8571428571429, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI87082295, Length=445, Percent_Identity=27.8651685393258, Blast_Score=132, Evalue=2e-31,
Organism=Escherichia coli, GI87081926, Length=453, Percent_Identity=24.9448123620309, Blast_Score=126, Evalue=8e-30,
Organism=Escherichia coli, GI1786504, Length=469, Percent_Identity=26.226012793177, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI1787653, Length=389, Percent_Identity=23.1362467866324, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17534447, Length=474, Percent_Identity=30.5907172995781, Blast_Score=185, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI115532534, Length=398, Percent_Identity=32.4120603015075, Blast_Score=162, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI133930964, Length=424, Percent_Identity=29.0094339622642, Blast_Score=157, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17562198, Length=457, Percent_Identity=29.5404814004376, Blast_Score=154, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI25144435, Length=480, Percent_Identity=27.7083333333333, Blast_Score=143, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI115534176, Length=454, Percent_Identity=27.9735682819383, Blast_Score=141, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32564736, Length=428, Percent_Identity=28.7383177570093, Blast_Score=138, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32564151, Length=434, Percent_Identity=27.8801843317972, Blast_Score=138, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17551164, Length=444, Percent_Identity=27.9279279279279, Blast_Score=134, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71995606, Length=447, Percent_Identity=25.503355704698, Blast_Score=125, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25143874, Length=466, Percent_Identity=25.7510729613734, Blast_Score=120, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI25143876, Length=466, Percent_Identity=25.7510729613734, Blast_Score=120, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71986308, Length=417, Percent_Identity=26.1390887290168, Blast_Score=115, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71995613, Length=382, Percent_Identity=25.6544502617801, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71990744, Length=309, Percent_Identity=29.126213592233, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17534119, Length=489, Percent_Identity=25.5623721881391, Blast_Score=101, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25146391, Length=340, Percent_Identity=25, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25146394, Length=340, Percent_Identity=25, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32566756, Length=340, Percent_Identity=25, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17564084, Length=335, Percent_Identity=25.9701492537313, Blast_Score=97, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6323821, Length=468, Percent_Identity=30.982905982906, Blast_Score=178, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6323822, Length=467, Percent_Identity=29.5503211991435, Blast_Score=171, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6325196, Length=456, Percent_Identity=29.6052631578947, Blast_Score=162, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6324950, Length=416, Percent_Identity=29.8076923076923, Blast_Score=157, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6320917, Length=436, Percent_Identity=29.3577981651376, Blast_Score=150, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6321826, Length=493, Percent_Identity=26.369168356998, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6319478, Length=435, Percent_Identity=27.3563218390805, Blast_Score=122, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6321828, Length=529, Percent_Identity=24.3856332703214, Blast_Score=104, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6323757, Length=337, Percent_Identity=24.9258160237389, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24668425, Length=474, Percent_Identity=29.1139240506329, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24668417, Length=474, Percent_Identity=29.1139240506329, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24668413, Length=474, Percent_Identity=29.1139240506329, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24585660, Length=465, Percent_Identity=27.3118279569892, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI20129399, Length=457, Percent_Identity=29.3216630196937, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI281362580, Length=425, Percent_Identity=28.9411764705882, Blast_Score=153, Evalue=6e-37,
Organism=Drosophila melanogaster, GI62472918, Length=425, Percent_Identity=28.9411764705882, Blast_Score=153, Evalue=6e-37,
Organism=Drosophila melanogaster, GI62472926, Length=425, Percent_Identity=28.9411764705882, Blast_Score=153, Evalue=6e-37,
Organism=Drosophila melanogaster, GI62472936, Length=425, Percent_Identity=28.9411764705882, Blast_Score=153, Evalue=6e-37,
Organism=Drosophila melanogaster, GI21356737, Length=425, Percent_Identity=28.9411764705882, Blast_Score=153, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24650465, Length=433, Percent_Identity=27.7136258660508, Blast_Score=147, Evalue=6e-35,
Organism=Drosophila melanogaster, GI28571806, Length=476, Percent_Identity=26.4705882352941, Blast_Score=129, Evalue=9e-30,
Organism=Drosophila melanogaster, GI28571798, Length=476, Percent_Identity=26.4705882352941, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571796, Length=476, Percent_Identity=26.4705882352941, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571794, Length=476, Percent_Identity=26.4705882352941, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571802, Length=476, Percent_Identity=26.4705882352941, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571800, Length=476, Percent_Identity=26.4705882352941, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24666674, Length=463, Percent_Identity=26.3498920086393, Blast_Score=120, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24638876, Length=417, Percent_Identity=26.378896882494, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24638878, Length=417, Percent_Identity=26.378896882494, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28574525, Length=470, Percent_Identity=21.4893617021277, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI45552499, Length=351, Percent_Identity=25.6410256410256, Blast_Score=83, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281360303, Length=347, Percent_Identity=25.6484149855908, Blast_Score=82, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281360299, Length=351, Percent_Identity=25.0712250712251, Blast_Score=80, Evalue=8e-15,
Organism=Drosophila melanogaster, GI281360297, Length=351, Percent_Identity=25.0712250712251, Blast_Score=80, Evalue=8e-15,
Organism=Drosophila melanogaster, GI281360295, Length=351, Percent_Identity=25.0712250712251, Blast_Score=80, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24586250, Length=351, Percent_Identity=25.0712250712251, Blast_Score=80, Evalue=8e-15,
Organism=Drosophila melanogaster, GI281360301, Length=347, Percent_Identity=25.0720461095101, Blast_Score=80, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 117443; Mature: 117312

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKQEETGMFQAKEVLSSSIIEQPLESLWSAISPLYMVDEAKWLHQLLPLAKPTDREAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHCCCCCCCCHHH
MMEKHAAILIQRVRDDKKAVQMIDALLLEYSLDTKEGILLMCLAEALMRIPDAETADALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHH
RDKLSVADWKSHLKNSDSTFVNASTWGLLLTGKVVSMDVKADGSPSNALSRLVNKFSEPV
HHHHHHHHHHHHHCCCCCCEEECCCCEEEEECEEEEEEECCCCCCHHHHHHHHHHHHHHH
IRQAMNQAMKIMGHQFVLGRTIEEAQKKGLSMREKGYTYSFDMLGEAALTQTDAHKYFKD
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHCCCEEEHHHHCHHHHHHHHHHHHHHH
YIMAIESVGRAASIANSPEPTVSIKLSALHPRYEVANKERVMNEMYQSVLQLLERARELD
HHHHHHHHCHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VGITIDAEEMDRLELSLELFEKLYRSDIVKGWGKFGLVVQAYSKRALPVLVWLTALSKEQ
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
EDLIPLRLVKGAYWDTELKLSQQFGFARYPVFTRKEATDVSYLACARYLLSEHVKGKIFP
CCCCHHHHHCCCCCCCHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCCH
QFASHNAHTVAAIASMATHDEFEFQRLHGMGDALYEHAMDMFNRSVRIYAPVGSHKDLLP
HHHCCCCHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHH
YLVRRLLENGANSSFVHRLVDANCPIESLTVHPVDSLLACPSLENQLIPLPPYIFSDRKN
HHHHHHHHCCCCHHHHHHHHCCCCCCCCEEECCHHHHHCCCCCCCCCCCCCCHHCCCCCC
SYSINLDVESEAHPFERQVKEQMKTYWQGGPIVSNIRDYESMIKEHGSALHVINSPYDRG
CEEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCC
NDVGSLVWSSQEQVSNALDIAHDYFPIWQQTPVAERADYLEALADKLEMNMPELVALCHK
CCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
EAGKTIHDSIDEVREAVDFCRYYAVQAKLNFTTAETIVGFDDISRQIERQGRGVFVCISP
HHCCHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHCHHHHHHHHHHCCCEEEEEECC
WNFPLAIFLGQVTAALVAGNTVIAKPAEQTSLIAVRAIELLLETGIAPQAVHLLPGDGKT
CCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCE
VGAPLTSDHRVAGVAFTGSTETAQLINRTLANRSIEGEGVSPVPFIAETGGQNAMIVDST
ECCCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCEEEEECC
ALPEQVVRDVIRSAFASAGQRCSALRVLFVQQDIADRIINLIKGAMAELSVGLPELHCTD
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECC
VGPVIDVRAKDKLMAHIERMTKEGVLVAQAELPNWSEKGDFVPPSAFEIESIKQLENEQF
CCCEEECCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
GPILHIVRFKASDIDKVISEINSTGFGLTMGVHSRNEVTYTRIEKNIKVGNCYINRDQVG
CHHHHHHHHCHHHHHHHHHHHCCCCCEEEEECCCCCCEEHEEHHCCEEEEEEEECCCCCC
AVVGVQPFGGQGLSGTGPKAGGPRYLIRYTKANTTTSK
EEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure 
SDKQEETGMFQAKEVLSSSIIEQPLESLWSAISPLYMVDEAKWLHQLLPLAKPTDREAV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHCCCCCCCCHHH
MMEKHAAILIQRVRDDKKAVQMIDALLLEYSLDTKEGILLMCLAEALMRIPDAETADALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHH
RDKLSVADWKSHLKNSDSTFVNASTWGLLLTGKVVSMDVKADGSPSNALSRLVNKFSEPV
HHHHHHHHHHHHHCCCCCCEEECCCCEEEEECEEEEEEECCCCCCHHHHHHHHHHHHHHH
IRQAMNQAMKIMGHQFVLGRTIEEAQKKGLSMREKGYTYSFDMLGEAALTQTDAHKYFKD
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHCCCEEEHHHHCHHHHHHHHHHHHHHH
YIMAIESVGRAASIANSPEPTVSIKLSALHPRYEVANKERVMNEMYQSVLQLLERARELD
HHHHHHHHCHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VGITIDAEEMDRLELSLELFEKLYRSDIVKGWGKFGLVVQAYSKRALPVLVWLTALSKEQ
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
EDLIPLRLVKGAYWDTELKLSQQFGFARYPVFTRKEATDVSYLACARYLLSEHVKGKIFP
CCCCHHHHHCCCCCCCHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCCH
QFASHNAHTVAAIASMATHDEFEFQRLHGMGDALYEHAMDMFNRSVRIYAPVGSHKDLLP
HHHCCCCHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHH
YLVRRLLENGANSSFVHRLVDANCPIESLTVHPVDSLLACPSLENQLIPLPPYIFSDRKN
HHHHHHHHCCCCHHHHHHHHCCCCCCCCEEECCHHHHHCCCCCCCCCCCCCCHHCCCCCC
SYSINLDVESEAHPFERQVKEQMKTYWQGGPIVSNIRDYESMIKEHGSALHVINSPYDRG
CEEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCC
NDVGSLVWSSQEQVSNALDIAHDYFPIWQQTPVAERADYLEALADKLEMNMPELVALCHK
CCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
EAGKTIHDSIDEVREAVDFCRYYAVQAKLNFTTAETIVGFDDISRQIERQGRGVFVCISP
HHCCHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHCHHHHHHHHHHCCCEEEEEECC
WNFPLAIFLGQVTAALVAGNTVIAKPAEQTSLIAVRAIELLLETGIAPQAVHLLPGDGKT
CCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCE
VGAPLTSDHRVAGVAFTGSTETAQLINRTLANRSIEGEGVSPVPFIAETGGQNAMIVDST
ECCCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCEEEEECC
ALPEQVVRDVIRSAFASAGQRCSALRVLFVQQDIADRIINLIKGAMAELSVGLPELHCTD
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECC
VGPVIDVRAKDKLMAHIERMTKEGVLVAQAELPNWSEKGDFVPPSAFEIESIKQLENEQF
CCCEEECCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
GPILHIVRFKASDIDKVISEINSTGFGLTMGVHSRNEVTYTRIEKNIKVGNCYINRDQVG
CHHHHHHHHCHHHHHHHHHHHCCCCCEEEEECCCCCCEEHEEHHCCEEEEEEEECCCCCC
AVVGVQPFGGQGLSGTGPKAGGPRYLIRYTKANTTTSK
EEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]