Click here to switch to the map view.

The map label for this gene is rseB [H]

Identifier: 172087752

GI number: 172087752

Start: 2328456

End: 2329382

Strand: Reverse

Name: rseB [H]

Synonym: VF_2091

Alternate gene names: 172087752

Gene position: 2329382-2328456 (Counterclockwise)

Preceding gene: 59712699

Following gene: 59712697

Centisome position: 80.39

GC content: 37.11

Gene sequence:

>927_bases
ATGGCCTCAGCTGAAGAAAAACCTTCTGCTGAGGCTTTGTTGCATCTGATGGGAGAGGCTAGCCATAATTTAAATTATGA
GCTTTCTTATATTTTAGTTAAGAAAAGTAGCATAGAACCTTTTATGTATCGTCATTCACATTCAGAGAATATGACGCTGT
CTCATTTAGTTTATTTGAGCGGTTCTATGCGTGAAGTGATTCGTCGAAACAACGAAATTAGTTACTTAGAGCAAGGTAGC
AAGCCATTTACGATAAAATCTGAAGCTATTGTCGCTCCGATTATTCCTCTTCTACATAAAGATATTGCACAATTAAAACA
GTATTACGATTTTGTATCTGTAGGTAGAGCAAGAGAAGCAGGTACGGCATCTCAAGTGGTGCGAATTGTTTCAAAAGACG
GTAATCGATATTCTTACATTGTCTGGATTGATGAGCGTAGTCATCTACCTATGAGAACTGATTTAGTCAGTCGAGAAGGT
GATATCATTGAGCAATATCGTGTCATTTCATATACCGTAAATGATCAAATTGCGACGTATATGACACAGCGATTAGGTGA
TGCTGAGCTACCTAAAGTACTTTCTATTCCAAGCTCGACAAGTGATAAAGCAACATGGGAAGTGACATGGATACCAAGTG
GATTTAAAAATATTCACTTCAACCGTTATCGTTTAGCGATGAATCAAAGAGCGGTAGAAAGTCAGATGTATTCTGATGGT
CTATTTAATTTTTCGGTTTATATCTCAGAAGCCGATAAACTCAGTCATAAAGAACAACTTGTTCGCCAAGGTCGTCGCTC
ATTACATAGTTATATTAAAGGCGATTATGAAATCAGTGTTGTTGGTGATATTCCAGCATTAACGGCTAAACGAATTGCTG
AATCAGTGGTGTTTAGTGAATCAAAACCTATTATTGAGGATAAGTAA

Upstream 100 bases:

>100_bases
TTCGATTGATAGAGAGCTGTTAGAACAAAATTCAACATTGGCAGAATAGATGAAACGTATCCTGATCAGCTTTATTGCAT
TGGTCAGCTTCTTTCCAATA

Downstream 100 bases:

>100_bases
GCGAAATGATGACTGCATTAGCTACCGTTCTTGAAGTACAAGAAGATATTGTAGTGGTGGGATGCCAACAAAAAACAAGT
TGTAACCACTGCTCATCAAA

Product: periplasmic negative regulator of sigmaE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MASAEEKPSAEALLHLMGEASHNLNYELSYILVKKSSIEPFMYRHSHSENMTLSHLVYLSGSMREVIRRNNEISYLEQGS
KPFTIKSEAIVAPIIPLLHKDIAQLKQYYDFVSVGRAREAGTASQVVRIVSKDGNRYSYIVWIDERSHLPMRTDLVSREG
DIIEQYRVISYTVNDQIATYMTQRLGDAELPKVLSIPSSTSDKATWEVTWIPSGFKNIHFNRYRLAMNQRAVESQMYSDG
LFNFSVYISEADKLSHKEQLVRQGRRSLHSYIKGDYEISVVGDIPALTAKRIAESVVFSESKPIIEDK

Sequences:

>Translated_308_residues
MASAEEKPSAEALLHLMGEASHNLNYELSYILVKKSSIEPFMYRHSHSENMTLSHLVYLSGSMREVIRRNNEISYLEQGS
KPFTIKSEAIVAPIIPLLHKDIAQLKQYYDFVSVGRAREAGTASQVVRIVSKDGNRYSYIVWIDERSHLPMRTDLVSREG
DIIEQYRVISYTVNDQIATYMTQRLGDAELPKVLSIPSSTSDKATWEVTWIPSGFKNIHFNRYRLAMNQRAVESQMYSDG
LFNFSVYISEADKLSHKEQLVRQGRRSLHSYIKGDYEISVVGDIPALTAKRIAESVVFSESKPIIEDK
>Mature_307_residues
ASAEEKPSAEALLHLMGEASHNLNYELSYILVKKSSIEPFMYRHSHSENMTLSHLVYLSGSMREVIRRNNEISYLEQGSK
PFTIKSEAIVAPIIPLLHKDIAQLKQYYDFVSVGRAREAGTASQVVRIVSKDGNRYSYIVWIDERSHLPMRTDLVSREGD
IIEQYRVISYTVNDQIATYMTQRLGDAELPKVLSIPSSTSDKATWEVTWIPSGFKNIHFNRYRLAMNQRAVESQMYSDGL
FNFSVYISEADKLSHKEQLVRQGRRSLHSYIKGDYEISVVGDIPALTAKRIAESVVFSESKPIIEDK

Specific function: Seems to modulate the activity of rpoE (sigma-E) [H]

COG id: COG3026

COG function: function code T; Negative regulator of sigma E activity

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rseB family [H]

Homologues:

Organism=Escherichia coli, GI1788924, Length=302, Percent_Identity=44.3708609271523, Blast_Score=281, Evalue=3e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005588 [H]

Pfam domain/function: PF03888 MucB_RseB [H]

EC number: NA

Molecular weight: Translated: 35162; Mature: 35031

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASAEEKPSAEALLHLMGEASHNLNYELSYILVKKSSIEPFMYRHSHSENMTLSHLVYLS
CCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHEECCCCCCCEEEHHEECC
GSMREVIRRNNEISYLEQGSKPFTIKSEAIVAPIIPLLHKDIAQLKQYYDFVSVGRAREA
CHHHHHHHCCCCCHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GTASQVVRIVSKDGNRYSYIVWIDERSHLPMRTDLVSREGDIIEQYRVISYTVNDQIATY
CCHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHCCCCCHHHHEEEEEEEECHHHHHH
MTQRLGDAELPKVLSIPSSTSDKATWEVTWIPSGFKNIHFNRYRLAMNQRAVESQMYSDG
HHHHCCCCCCCCEEECCCCCCCCEEEEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHCC
LFNFSVYISEADKLSHKEQLVRQGRRSLHSYIKGDYEISVVGDIPALTAKRIAESVVFSE
CEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCC
SKPIIEDK
CCCCCCCC
>Mature Secondary Structure 
ASAEEKPSAEALLHLMGEASHNLNYELSYILVKKSSIEPFMYRHSHSENMTLSHLVYLS
CCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHEECCCCCCCEEEHHEECC
GSMREVIRRNNEISYLEQGSKPFTIKSEAIVAPIIPLLHKDIAQLKQYYDFVSVGRAREA
CHHHHHHHCCCCCHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GTASQVVRIVSKDGNRYSYIVWIDERSHLPMRTDLVSREGDIIEQYRVISYTVNDQIATY
CCHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHCCCCCHHHHEEEEEEEECHHHHHH
MTQRLGDAELPKVLSIPSSTSDKATWEVTWIPSGFKNIHFNRYRLAMNQRAVESQMYSDG
HHHHCCCCCCCCEEECCCCCCCCEEEEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHCC
LFNFSVYISEADKLSHKEQLVRQGRRSLHSYIKGDYEISVVGDIPALTAKRIAESVVFSE
CEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCC
SKPIIEDK
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]