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The map label for this gene is dinB

Identifier: 170762215

GI number: 170762215

Start: 498427

End: 499509

Strand: Direct

Name: dinB

Synonym: UPA3_0457

Alternate gene names: 170762215

Gene position: 498427-499509 (Clockwise)

Preceding gene: 170762432

Following gene: 170762017

Centisome position: 66.31

GC content: 21.51

Gene sequence:

>1083_bases
ATGAAAAATAATCATCAAAAAATCATCATGCATCTTGATATCGATGCTTTTTATGCTACTGTTAGTGAACTATTACATCC
TGAATATAAAAATTTTCCAATTGCTGTTGGTTCATTAAATTCACGCACAGGTATTATTTCTTCACCTAACTATTTAGCAC
GTTCTTATGGCGTTAAAGCTGCAATGCCTATCTTTTTAGCTAAAGAATTATGTCCAAATTTAATTATTTTACCTTCTGAA
CACAATATTTATCAATCTTACTCAAAACATTTTTTTCAAATCATTAATAAATATACAAATAAGATTGAAATAACTTCAAT
TGATGAATGCTTTATTGATGCAACAGATTTAGTTAAAAAATATCATAATAATATCCGCTTGTTAGCAACAAAAATACAAA
AAGAAATCAAAAACAAACTAAACCTTAGTATTTCAATTGGAATTTCATATAATAAAACAATTGCAAAAATGGCAACGGAA
TTAAATAAACCTTCTGGTATATCAATTATTGATGAAAATAAAATTATTAATTTAATTTATGAATTAAATATCAATAAAAT
TCCCTATATTGGCGAAATAAAATCACAAGAATTATATGCGATTAACATTTTTAAAATTAAAGAATTAATTGCAACTGAAA
ATAAACAAAAAATTTCATTAGTTTTAGGTTCAATATATCAAAATTTAGTCAATGATTTAAAAGGTTTAAGTAAAATTAAA
ATAATTGATGAAGATATTTATAAAACAATTTCACATTCGAAAACATTTAACGAAGATTTGAATGATTTTTATGAAATTTC
TAATGAAATGAACGATTTAATTTTAACTGTTACTAATCGATTAAAAAAATGTAATTTAATGACTAATAACATCAGTATTT
ATATTAAATATCCTAGTTTTAAAACAAAAATTAAGCAAAAACAATTAACTTATTACACTGATGATTATCAAACCATTTTT
CTAGCAATTAAAAACTTATTTAAAATAATGTATAAAGATGAAACAATACGTTTAATTGGTATCTCACTAAATAAATTAGT
AAAAAAAGAAAATGTTAAAAAACAATTATTTTTATTTGATTAA

Upstream 100 bases:

>100_bases
TTAGCAAAAAATTATGACTTTGAATGTAAACATTTAACTCCTACTGATATTTTTGATGAAAAAAAACAAAATCAAGAATA
TATGATATTTTTACAAAAGC

Downstream 100 bases:

>100_bases
TTGATTGTTTTTTAAAAATCTATTCCTTCAATTGTAATTTTTCGACCTCTTAAATTCTTATTTATAAAATGATGTTGAAT
TAAATAAGGTTCTATTTTTG

Product: DNA polymerase IV (Pol IV)

Products: NA

Alternate protein names: Pol IV

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MKNNHQKIIMHLDIDAFYATVSELLHPEYKNFPIAVGSLNSRTGIISSPNYLARSYGVKAAMPIFLAKELCPNLIILPSE
HNIYQSYSKHFFQIINKYTNKIEITSIDECFIDATDLVKKYHNNIRLLATKIQKEIKNKLNLSISIGISYNKTIAKMATE
LNKPSGISIIDENKIINLIYELNINKIPYIGEIKSQELYAINIFKIKELIATENKQKISLVLGSIYQNLVNDLKGLSKIK
IIDEDIYKTISHSKTFNEDLNDFYEISNEMNDLILTVTNRLKKCNLMTNNISIYIKYPSFKTKIKQKQLTYYTDDYQTIF
LAIKNLFKIMYKDETIRLIGISLNKLVKKENVKKQLFLFD

Sequences:

>Translated_360_residues
MKNNHQKIIMHLDIDAFYATVSELLHPEYKNFPIAVGSLNSRTGIISSPNYLARSYGVKAAMPIFLAKELCPNLIILPSE
HNIYQSYSKHFFQIINKYTNKIEITSIDECFIDATDLVKKYHNNIRLLATKIQKEIKNKLNLSISIGISYNKTIAKMATE
LNKPSGISIIDENKIINLIYELNINKIPYIGEIKSQELYAINIFKIKELIATENKQKISLVLGSIYQNLVNDLKGLSKIK
IIDEDIYKTISHSKTFNEDLNDFYEISNEMNDLILTVTNRLKKCNLMTNNISIYIKYPSFKTKIKQKQLTYYTDDYQTIF
LAIKNLFKIMYKDETIRLIGISLNKLVKKENVKKQLFLFD
>Mature_360_residues
MKNNHQKIIMHLDIDAFYATVSELLHPEYKNFPIAVGSLNSRTGIISSPNYLARSYGVKAAMPIFLAKELCPNLIILPSE
HNIYQSYSKHFFQIINKYTNKIEITSIDECFIDATDLVKKYHNNIRLLATKIQKEIKNKLNLSISIGISYNKTIAKMATE
LNKPSGISIIDENKIINLIYELNINKIPYIGEIKSQELYAINIFKIKELIATENKQKISLVLGSIYQNLVNDLKGLSKIK
IIDEDIYKTISHSKTFNEDLNDFYEISNEMNDLILTVTNRLKKCNLMTNNISIYIKYPSFKTKIKQKQLTYYTDDYQTIF
LAIKNLFKIMYKDETIRLIGISLNKLVKKENVKKQLFLFD

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI7705344, Length=115, Percent_Identity=42.6086956521739, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI154350220, Length=330, Percent_Identity=25.4545454545455, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI84043967, Length=411, Percent_Identity=22.6277372262774, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI7706681, Length=319, Percent_Identity=23.8244514106583, Blast_Score=85, Evalue=9e-17,
Organism=Escherichia coli, GI1786425, Length=357, Percent_Identity=29.1316526610644, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1787432, Length=375, Percent_Identity=24, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193205700, Length=405, Percent_Identity=25.1851851851852, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17537959, Length=265, Percent_Identity=24.5283018867925, Blast_Score=98, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6324921, Length=203, Percent_Identity=29.5566502463054, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19923006, Length=432, Percent_Identity=24.537037037037, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21355641, Length=230, Percent_Identity=28.2608695652174, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24644984, Length=230, Percent_Identity=28.2608695652174, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24668444, Length=168, Percent_Identity=30.952380952381, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO4_UREP2 (B1AJ79)

Other databases:

- EMBL:   CP000942
- RefSeq:   YP_001752523.1
- ProteinModelPortal:   B1AJ79
- SMR:   B1AJ79
- GeneID:   6155177
- GenomeReviews:   CP000942_GR
- KEGG:   upa:UPA3_0457
- HOGENOM:   HBG734504
- OMA:   GDEHIIR
- ProtClustDB:   CLSK2298939
- BioCyc:   UPAR505682:UPA3_0457-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 41723; Mature: 41723

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 109-109

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNHQKIIMHLDIDAFYATVSELLHPEYKNFPIAVGSLNSRTGIISSPNYLARSYGVKA
CCCCCEEEEEEEEHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCHHHHHCCCCH
AMPIFLAKELCPNLIILPSEHNIYQSYSKHFFQIINKYTNKIEITSIDECFIDATDLVKK
HHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHCCHHHHHHH
YHNNIRLLATKIQKEIKNKLNLSISIGISYNKTIAKMATELNKPSGISIIDENKIINLIY
HHCCCEEHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCCCCEEEECCCEEEEEE
ELNINKIPYIGEIKSQELYAINIFKIKELIATENKQKISLVLGSIYQNLVNDLKGLSKIK
EECCCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
IIDEDIYKTISHSKTFNEDLNDFYEISNEMNDLILTVTNRLKKCNLMTNNISIYIKYPSF
EEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCEEEEEECCCH
KTKIKQKQLTYYTDDYQTIFLAIKNLFKIMYKDETIRLIGISLNKLVKKENVKKQLFLFD
HHHHHHHHEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHCCCCEEEECC
>Mature Secondary Structure
MKNNHQKIIMHLDIDAFYATVSELLHPEYKNFPIAVGSLNSRTGIISSPNYLARSYGVKA
CCCCCEEEEEEEEHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCHHHHHCCCCH
AMPIFLAKELCPNLIILPSEHNIYQSYSKHFFQIINKYTNKIEITSIDECFIDATDLVKK
HHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHCCHHHHHHH
YHNNIRLLATKIQKEIKNKLNLSISIGISYNKTIAKMATELNKPSGISIIDENKIINLIY
HHCCCEEHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCCCCEEEECCCEEEEEE
ELNINKIPYIGEIKSQELYAINIFKIKELIATENKQKISLVLGSIYQNLVNDLKGLSKIK
EECCCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
IIDEDIYKTISHSKTFNEDLNDFYEISNEMNDLILTVTNRLKKCNLMTNNISIYIKYPSF
EEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCEEEEEECCCH
KTKIKQKQLTYYTDDYQTIFLAIKNLFKIMYKDETIRLIGISLNKLVKKENVKKQLFLFD
HHHHHHHHEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA