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The map label for this gene is mtnN

Identifier: 170762160

GI number: 170762160

Start: 536283

End: 536975

Strand: Direct

Name: mtnN

Synonym: UPA3_0489

Alternate gene names: 170762160

Gene position: 536283-536975 (Clockwise)

Preceding gene: 170762419

Following gene: 170762380

Centisome position: 71.34

GC content: 26.55

Gene sequence:

>693_bases
ATGATTGGTTTAATTGTGGCATTAAATAGTGAAATTAAAACCTTTTTTAAACAAATTAAAAAGAAGGTTTATCAAATTAA
TAATATTGATTTTTACTTGTGCACTCATCAAAATATAGAATTTGTTTTAGTTTTTACGGATGTAGGAAAAACTAATGCGA
GTTTTATTACTGCATTATTAATTAATAATTTTAAACCTAAAGTGATTTTAAACGTTGGTAGTTGTGGTGCACTAAATGAT
CAGTTACAGGTTTTAGATATTGCCATTATTGATCAATGCCAATACTTAGATGTTAACGTTAGCGCTTTTGGTTATTTAAA
AAATCAAATACCGCGTTTAGATAAATTTTTTATTTTAGATAAAAGTTATAATCAACAAATCAAAAACCAGTTAATTAAGA
AAAAACTAAAATGTTGAATTGCAAATGTTGGAAGCAGTGACACATTTATTAATCGTGATAACATCTCCTTTTTTTATGAT
CAACAAATCGACTTAGTTGATATGGAATTAGCAGCTATTGCTCATGTATGCACGCGTATGTTAACACCACTAGTAAGTAT
TAAATTAGTTAGTGATCATATTACTCTTCCCAATTCCAATCAAGAACAGTTTAATAAAAACTTATCACTAATTGATAAAT
GATTTAATGAGCATTTACCATCCATTATTGAAGCAATTTTAGAGATCTACTAA

Upstream 100 bases:

>100_bases
TAACATTGATTATTATCGAAAATTAGTTTTTGAAGATCTAGATAAGGCATTTATTGAAGTTTATCAATACCAACAAAGAC
AAAGAAAATAAGGTAAAAAT

Downstream 100 bases:

>100_bases
TTTATTTTTGTAAAAAATATTAAAATTACAAAATCTACTATTATTTTTTAAATTGTTTTATAATTTACGTATATAAAAAG
TTAGTTAAATAAGGAGTAGT

Product: MTA/SAH nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MIGLIVALNSEIKTFFKQIKKKVYQINNIDFYLCTHQNIEFVLVFTDVGKTNASFITALLINNFKPKVILNVGSCGALND
QLQVLDIAIIDQCQYLDVNVSAFGYLKNQIPRLDKFFILDKSYNQQIKNQLIKKKLKCWIANVGSSDTFINRDNISFFYD
QQIDLVDMELAAIAHVCTRMLTPLVSIKLVSDHITLPNSNQEQFNKNLSLIDKWFNEHLPSIIEAILEIY

Sequences:

>Translated_230_residues
MIGLIVALNSEIKTFFKQIKKKVYQINNIDFYLCTHQNIEFVLVFTDVGKTNASFITALLINNFKPKVILNVGSCGALND
QLQVLDIAIIDQCQYLDVNVSAFGYLKNQIPRLDKFFILDKSYNQQIKNQLIKKKLKC*IANVGSSDTFINRDNISFFYD
QQIDLVDMELAAIAHVCTRMLTPLVSIKLVSDHITLPNSNQEQFNKNLSLIDK*FNEHLPSIIEAILEIY
>Mature_230_residues
MIGLIVALNSEIKTFFKQIKKKVYQINNIDFYLCTHQNIEFVLVFTDVGKTNASFITALLINNFKPKVILNVGSCGALND
QLQVLDIAIIDQCQYLDVNVSAFGYLKNQIPRLDKFFILDKSYNQQIKNQLIKKKLKC*IANVGSSDTFINRDNISFFYD
QQIDLVDMELAAIAHVCTRMLTPLVSIKLVSDHITLPNSNQEQFNKNLSLIDK*FNEHLPSIIEAILEIY

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=196, Percent_Identity=31.1224489795918, Blast_Score=88, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 26005; Mature: 26005

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGLIVALNSEIKTFFKQIKKKVYQINNIDFYLCTHQNIEFVLVFTDVGKTNASFITALL
CEEEEEEECHHHHHHHHHHHHHHHEECCEEEEEEECCCEEEEEEEECCCCCCHHHHHHHH
INNFKPKVILNVGSCGALNDQLQVLDIAIIDQCQYLDVNVSAFGYLKNQIPRLDKFFILD
HCCCCCEEEEEECCCCCCCCCHHEEEEEECCCCEEEEECHHHHHHHHHCCCCCCEEEEEC
KSYNQQIKNQLIKKKLKCIANVGSSDTFINRDNISFFYDQQIDLVDMELAAIAHVCTRML
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEECCCCCEEHHHHHHHHHHHHHHH
TPLVSIKLVSDHITLPNSNQEQFNKNLSLIDKFNEHLPSIIEAILEIY
HHHHEEEEEECEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIGLIVALNSEIKTFFKQIKKKVYQINNIDFYLCTHQNIEFVLVFTDVGKTNASFITALL
CEEEEEEECHHHHHHHHHHHHHHHEECCEEEEEEECCCEEEEEEEECCCCCCHHHHHHHH
INNFKPKVILNVGSCGALNDQLQVLDIAIIDQCQYLDVNVSAFGYLKNQIPRLDKFFILD
HCCCCCEEEEEECCCCCCCCCHHEEEEEECCCCEEEEECHHHHHHHHHCCCCCCEEEEEC
KSYNQQIKNQLIKKKLKCIANVGSSDTFINRDNISFFYDQQIDLVDMELAAIAHVCTRML
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEECCCCCEEHHHHHHHHHHHHHHH
TPLVSIKLVSDHITLPNSNQEQFNKNLSLIDKFNEHLPSIIEAILEIY
HHHHEEEEEECEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA