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The map label for this gene is 170762027

Identifier: 170762027

GI number: 170762027

Start: 709848

End: 711638

Strand: Reverse

Name: 170762027

Synonym: UPA3_0609

Alternate gene names: NA

Gene position: 711638-709848 (Counterclockwise)

Preceding gene: 170762038

Following gene: 170761949

Centisome position: 94.67

GC content: 28.75

Gene sequence:

>1791_bases
ATGGAAAATACCAAAAAAAGTCCTACATATGTTTATGCTTTAGGGGGGCTAGAAGAAATTGGTAAAAACACTTATGTTGT
TGAACATGAAGATGAAATTATTTTAATTGATGCGGGCATTAAATTTGCTAATGCATCTTTACCAGGATTTGATGGAACTG
TTGCCAATTTTGATTATTTAATAAAAAACAATCATAAAATTCATTCATTAGTAGTTACTCATGGTCATGAAGACCATATT
GGGGGGATTCCTCACATTTTGCGACATGTTAAAATTAAGACTATCTATGCACCAACATTAGCAGCAAAATTAATTGAACG
TCGTTTAAGTGAATATAAAGATATTAAACCTCCGCGTATTATTGTCTTTGAAGATGAGTCAATGTATAAAACAAAATATT
TTGAAGTTGATTTTTATCGTGTTTGTCATTCAATTCCTGATTCATTTGGAATTTGTGTAAAAACACCAAACGGATACATT
GTAACAACTGGTGATTTTAGATTTGATTTTGCTACAGCTGGTGATGAGACTAATTTAGCTAAGATTTCACAAATTTCTAA
TCGTGGAATCTCAGTATTAATGTGCGAATCAACAAGTGCTGAAATTCCTGGATTTAGTGAAAGTGAACGATATGTTATTG
ATAACATTCGTGATTATATGGTAAATATTAAAGGACGAACTTTTATTTCAACATTTGCTTCTAATTTAGGTCGTGTTGAA
GAAATTATTGCTATAGCTGTTGGTTTAAATAAAAAAATCTGTATCATTGGTAAATCAATGGAAGCTAATATTAAAACAAG
TCGAAAATTGGGTTATTTAAATGTTCCTGAATCTTCATTTATCACACATAAAGAATTGCCATTTTATAAAGATCATGAAA
TTGTTGTAATTTTAACTGGTTCACAAGGTGAAAAAATGGCGGCTTTAAATGTTATGGCTAATAATAACCACTCAAAAATT
ACTTTAAAACCATCAGATACAATTATCTTATCATCAAATCCAATCCCAGGAAACTATGCTCAAGTCGAAGCAATGGTTAA
TAAACTTTATAAACTCGGATTAACAGTTTATGAAAATTCACCTAACAAAAAGATTCATGCTTCTGGTCATGCCACACGGA
GTGAACACCAATTAATGATTAAAGCAATTAATCCATCATATTTATTTCCAATCCATGGGGAATATAAAATGTTTCGTGCT
TTAAAACAAAATGCTGTTGACCAAGGTTTTGATAAAGACCATGTCATTATTGCACCAAATGGCCAAAAATTACAATTATT
AGATGGTGTTTTAAGTCATACTAATATTTATGTTGATGCTGAACCTAAATTTATTAATGGTTATGAAATTAGTTCTAAAA
TTAGTAAATTATTAAGTGAACGTGTTGTTTTATCCAGTGATGGTATTTTAAATCTAGTTTTAAATGCTGATTTTAAAAAA
GCTAAGTTAAACTCTGCTGTAAGTATTTCAACACGAGGATGTTTTTTTGCCAAAGAATCAACTAATTTAATTAATAAAAT
TTCTAATGTAGCAAAATCAAGTTTAGAAGAAGCGTTGGCAAAAAAAGAATTTGATGAAAAAAAACTAAAAGAAATAGTTA
GTGGAAATGTTAAATCAATTGTTTGAAAATGACGTAAGAAAAATCCAATTATTAATGTCACAATTATTAATAATGATTTG
GTCGAACAGTTTAGAAAAGACAATAATTATGTTGAATTTATCAAACAAGCTGAAGTTGAAGAAATTGAACAAGAAGTTGA
TATTGATGATTTAATTTCAAACGGTTTATAA

Upstream 100 bases:

>100_bases
TAATAATATATATCAAGATTTGTATAAATGATGTTACAACATTGTTTATATGTTTATATAAATAAATTTTTAATAATAAA
ACCAATTATAAGGAGTTAAA

Downstream 100 bases:

>100_bases
AAATTAGAGCCTTTAAGGAAATTATAAAATATGCAATATAAGATGTTAGTTATTGATCTAGATGGTACTTTATTAACGAA
AACAAAAAACATTAGTAAAG

Product: metallo-beta-lactamase superfamily protein

Products: NA

Alternate protein names: RNase J [H]

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MENTKKSPTYVYALGGLEEIGKNTYVVEHEDEIILIDAGIKFANASLPGFDGTVANFDYLIKNNHKIHSLVVTHGHEDHI
GGIPHILRHVKIKTIYAPTLAAKLIERRLSEYKDIKPPRIIVFEDESMYKTKYFEVDFYRVCHSIPDSFGICVKTPNGYI
VTTGDFRFDFATAGDETNLAKISQISNRGISVLMCESTSAEIPGFSESERYVIDNIRDYMVNIKGRTFISTFASNLGRVE
EIIAIAVGLNKKICIIGKSMEANIKTSRKLGYLNVPESSFITHKELPFYKDHEIVVILTGSQGEKMAALNVMANNNHSKI
TLKPSDTIILSSNPIPGNYAQVEAMVNKLYKLGLTVYENSPNKKIHASGHATRSEHQLMIKAINPSYLFPIHGEYKMFRA
LKQNAVDQGFDKDHVIIAPNGQKLQLLDGVLSHTNIYVDAEPKFINGYEISSKISKLLSERVVLSSDGILNLVLNADFKK
AKLNSAVSISTRGCFFAKESTNLINKISNVAKSSLEEALAKKEFDEKKLKEIVSGNVKSIVWKWRKKNPIINVTIINNDL
VEQFRKDNNYVEFIKQAEVEEIEQEVDIDDLISNGL

Sequences:

>Translated_596_residues
MENTKKSPTYVYALGGLEEIGKNTYVVEHEDEIILIDAGIKFANASLPGFDGTVANFDYLIKNNHKIHSLVVTHGHEDHI
GGIPHILRHVKIKTIYAPTLAAKLIERRLSEYKDIKPPRIIVFEDESMYKTKYFEVDFYRVCHSIPDSFGICVKTPNGYI
VTTGDFRFDFATAGDETNLAKISQISNRGISVLMCESTSAEIPGFSESERYVIDNIRDYMVNIKGRTFISTFASNLGRVE
EIIAIAVGLNKKICIIGKSMEANIKTSRKLGYLNVPESSFITHKELPFYKDHEIVVILTGSQGEKMAALNVMANNNHSKI
TLKPSDTIILSSNPIPGNYAQVEAMVNKLYKLGLTVYENSPNKKIHASGHATRSEHQLMIKAINPSYLFPIHGEYKMFRA
LKQNAVDQGFDKDHVIIAPNGQKLQLLDGVLSHTNIYVDAEPKFINGYEISSKISKLLSERVVLSSDGILNLVLNADFKK
AKLNSAVSISTRGCFFAKESTNLINKISNVAKSSLEEALAKKEFDEKKLKEIVSGNVKSIV*K*RKKNPIINVTIINNDL
VEQFRKDNNYVEFIKQAEVEEIEQEVDIDDLISNGL
>Mature_596_residues
MENTKKSPTYVYALGGLEEIGKNTYVVEHEDEIILIDAGIKFANASLPGFDGTVANFDYLIKNNHKIHSLVVTHGHEDHI
GGIPHILRHVKIKTIYAPTLAAKLIERRLSEYKDIKPPRIIVFEDESMYKTKYFEVDFYRVCHSIPDSFGICVKTPNGYI
VTTGDFRFDFATAGDETNLAKISQISNRGISVLMCESTSAEIPGFSESERYVIDNIRDYMVNIKGRTFISTFASNLGRVE
EIIAIAVGLNKKICIIGKSMEANIKTSRKLGYLNVPESSFITHKELPFYKDHEIVVILTGSQGEKMAALNVMANNNHSKI
TLKPSDTIILSSNPIPGNYAQVEAMVNKLYKLGLTVYENSPNKKIHASGHATRSEHQLMIKAINPSYLFPIHGEYKMFRA
LKQNAVDQGFDKDHVIIAPNGQKLQLLDGVLSHTNIYVDAEPKFINGYEISSKISKLLSERVVLSSDGILNLVLNADFKK
AKLNSAVSISTRGCFFAKESTNLINKISNVAKSSLEEALAKKEFDEKKLKEIVSGNVKSIV*K*RKKNPIINVTIINNDL
VEQFRKDNNYVEFIKQAEVEEIEQEVDIDDLISNGL

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 66432; Mature: 66432

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENTKKSPTYVYALGGLEEIGKNTYVVEHEDEIILIDAGIKFANASLPGFDGTVANFDYL
CCCCCCCCCEEEEECCHHHHCCCCEEEEECCCEEEEECCCEEECCCCCCCCCCCCCEEEE
IKNNHKIHSLVVTHGHEDHIGGIPHILRHVKIKTIYAPTLAAKLIERRLSEYKDIKPPRI
ECCCCEEEEEEEECCCCCCCCCHHHHHHHEEEEEEECHHHHHHHHHHHHHHHHCCCCCEE
IVFEDESMYKTKYFEVDFYRVCHSIPDSFGICVKTPNGYIVTTGDFRFDFATAGDETNLA
EEECCCCCEEEEEEEEHHHHHHHHCCCCCEEEEECCCCEEEEECCEEEEEECCCCCCCHH
KISQISNRGISVLMCESTSAEIPGFSESERYVIDNIRDYMVNIKGRTFISTFASNLGRVE
HHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHCHHHHEEECCCCHHHHHHHHHHHHHH
EIIAIAVGLNKKICIIGKSMEANIKTSRKLGYLNVPESSFITHKELPFYKDHEIVVILTG
HHHHHEECCCCEEEEEECCCCCCCCCCCCCCEEECCCCCCCEECCCCCCCCCCEEEEEEC
SQGEKMAALNVMANNNHSKITLKPSDTIILSSNPIPGNYAQVEAMVNKLYKLGLTVYENS
CCCCEEEEEEEEECCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEECC
PNKKIHASGHATRSEHQLMIKAINPSYLFPIHGEYKMFRALKQNAVDQGFDKDHVIIAPN
CCCEEEECCCCCCCCCEEEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCCEEEECCC
GQKLQLLDGVLSHTNIYVDAEPKFINGYEISSKISKLLSERVVLSSDGILNLVLNADFKK
CCEEHHHHHHHHCCEEEEECCCCEECCEEHHHHHHHHHHHCEEECCCCEEEEEEECCCCH
AKLNSAVSISTRGCFFAKESTNLINKISNVAKSSLEEALAKKEFDEKKLKEIVSGNVKSI
HHCCCEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHH
VKRKKNPIINVTIINNDLVEQFRKDNNYVEFIKQAEVEEIEQEVDIDDLISNGL
HHHCCCCEEEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCC
>Mature Secondary Structure
MENTKKSPTYVYALGGLEEIGKNTYVVEHEDEIILIDAGIKFANASLPGFDGTVANFDYL
CCCCCCCCCEEEEECCHHHHCCCCEEEEECCCEEEEECCCEEECCCCCCCCCCCCCEEEE
IKNNHKIHSLVVTHGHEDHIGGIPHILRHVKIKTIYAPTLAAKLIERRLSEYKDIKPPRI
ECCCCEEEEEEEECCCCCCCCCHHHHHHHEEEEEEECHHHHHHHHHHHHHHHHCCCCCEE
IVFEDESMYKTKYFEVDFYRVCHSIPDSFGICVKTPNGYIVTTGDFRFDFATAGDETNLA
EEECCCCCEEEEEEEEHHHHHHHHCCCCCEEEEECCCCEEEEECCEEEEEECCCCCCCHH
KISQISNRGISVLMCESTSAEIPGFSESERYVIDNIRDYMVNIKGRTFISTFASNLGRVE
HHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHCHHHHEEECCCCHHHHHHHHHHHHHH
EIIAIAVGLNKKICIIGKSMEANIKTSRKLGYLNVPESSFITHKELPFYKDHEIVVILTG
HHHHHEECCCCEEEEEECCCCCCCCCCCCCCEEECCCCCCCEECCCCCCCCCCEEEEEEC
SQGEKMAALNVMANNNHSKITLKPSDTIILSSNPIPGNYAQVEAMVNKLYKLGLTVYENS
CCCCEEEEEEEEECCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEECC
PNKKIHASGHATRSEHQLMIKAINPSYLFPIHGEYKMFRALKQNAVDQGFDKDHVIIAPN
CCCEEEECCCCCCCCCEEEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCCEEEECCC
GQKLQLLDGVLSHTNIYVDAEPKFINGYEISSKISKLLSERVVLSSDGILNLVLNADFKK
CCEEHHHHHHHHCCEEEEECCCCEECCEEHHHHHHHHHHHCEEECCCCEEEEEEECCCCH
AKLNSAVSISTRGCFFAKESTNLINKISNVAKSSLEEALAKKEFDEKKLKEIVSGNVKSI
HHCCCEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHH
VKRKKNPIINVTIINNDLVEQFRKDNNYVEFIKQAEVEEIEQEVDIDDLISNGL
HHHCCCCEEEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]