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The map label for this gene is aspB

Identifier: 170757853

GI number: 170757853

Start: 2163621

End: 2164772

Strand: Reverse

Name: aspB

Synonym: CLD_2610

Alternate gene names: 170757853

Gene position: 2164772-2163621 (Counterclockwise)

Preceding gene: 170754880

Following gene: 170755768

Centisome position: 54.69

GC content: 30.38

Gene sequence:

>1152_bases
ATGAAAGATAAATTTTTAGCTCATAAGTACAAAGAAAACGAAAATAATTTAATGTCAGAAACCGCTAATTTGAAAAATAA
GTTTAAAGATATAATTGATTTAAGCTTAGGGGATCCAGATATAATAACAGACAAATCTATCATAAAGATGGCCTTTAAGG
ATACAAAAAAAGGGTATACTAGATATTCAGATCCTACAGGAGATAAAGAATTAATAGAGGAAATTATTAATTTTTATAAC
AAAGATCGCAATATAAATTTTAAGGAAAATGAAGTTATGGCAGTAGTGGGAGCTTGTCATGGTATGTATTTAGCTCTGCA
ATCCATTATAAACCCTGGAGAAGAAGTAATAGTCCATTCTCCTTATTTTACTCCATACAAAGAACAAATAGAGATGGTAG
GTGGAAAATTTATTGAATTTGAAACCTTAGAGGAAGATGAGTTTAATATAAATCCTAAAAAATTAGAGAAATTAATAAAC
AGTAAAACAAAAGCTATAGTATTAAATTCCCCTAATAATCCTACCGGAGCATTTTTCCCCAAAGAATTACTAAAAGAAAT
AGCTAAAATAGCCATAGAAAATGATTTAGTTGTAATATCTGATGAGGTTTATGATGGATTTACTTATTATGAGGATTTTT
GCTCCATAGCTTCCTTAGAAGGGATGAAAGAGAGAACCATAACCTTAGGTAGCTTTTCAAAGGATTTTTGTATGACTGGG
TGGAGAGTTGGTTATGTAGCTGCTCCAGATTATATAATTAATACTATGAAAAACATTAATGAAGGTATATGTTTTTCTGC
TCCTACAATTTCTCAAAGAGCTGCTATATATGCTTTGAAAAATAGAGATAACATTGTAGATAAAATAAAGAAGGAATTTA
GAGAAAGAATGGAATATGCCTATAGTAGAATAGGGTCTATGCCTAAATTAAGTGCGTTTAAACCTAAAGCAGGCATATAT
ATATTTGCGAATATAAAGGAAACAGGCAAGAGTTCTGAAGAGTTTTGTGATGAATTATTAAACAAAGCTCATATAGTAGC
AATACCGGGAAAGGCCTTTGGTAAGTATGGAGAAGGCTACATAAGAATTGCTTGTACAGTAGGGTTAGAGGAATTAGAGC
AAGCTTTTGATAGAATTGAAAAAATACTATAA

Upstream 100 bases:

>100_bases
CTAGAGGAAGGCACACCCGAGGATATATTTAATAATGCTAAAAATCCACGAACAAAGGACTTTCTAAGTAAAATAATTTA
GTTTAGAAAAGGGGTATGTT

Downstream 100 bases:

>100_bases
ACAGAGTTTTTGGCTTCAGAGGGAGTATTTACTCCTACTAAAGCTTAGGAAATGGTTATCCGATGACTACCCGCTCTTTA
CTCCCACTTTGAAGAAGATA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MKDKFLAHKYKENENNLMSETANLKNKFKDIIDLSLGDPDIITDKSIIKMAFKDTKKGYTRYSDPTGDKELIEEIINFYN
KDRNINFKENEVMAVVGACHGMYLALQSIINPGEEVIVHSPYFTPYKEQIEMVGGKFIEFETLEEDEFNINPKKLEKLIN
SKTKAIVLNSPNNPTGAFFPKELLKEIAKIAIENDLVVISDEVYDGFTYYEDFCSIASLEGMKERTITLGSFSKDFCMTG
WRVGYVAAPDYIINTMKNINEGICFSAPTISQRAAIYALKNRDNIVDKIKKEFRERMEYAYSRIGSMPKLSAFKPKAGIY
IFANIKETGKSSEEFCDELLNKAHIVAIPGKAFGKYGEGYIRIACTVGLEELEQAFDRIEKIL

Sequences:

>Translated_383_residues
MKDKFLAHKYKENENNLMSETANLKNKFKDIIDLSLGDPDIITDKSIIKMAFKDTKKGYTRYSDPTGDKELIEEIINFYN
KDRNINFKENEVMAVVGACHGMYLALQSIINPGEEVIVHSPYFTPYKEQIEMVGGKFIEFETLEEDEFNINPKKLEKLIN
SKTKAIVLNSPNNPTGAFFPKELLKEIAKIAIENDLVVISDEVYDGFTYYEDFCSIASLEGMKERTITLGSFSKDFCMTG
WRVGYVAAPDYIINTMKNINEGICFSAPTISQRAAIYALKNRDNIVDKIKKEFRERMEYAYSRIGSMPKLSAFKPKAGIY
IFANIKETGKSSEEFCDELLNKAHIVAIPGKAFGKYGEGYIRIACTVGLEELEQAFDRIEKIL
>Mature_383_residues
MKDKFLAHKYKENENNLMSETANLKNKFKDIIDLSLGDPDIITDKSIIKMAFKDTKKGYTRYSDPTGDKELIEEIINFYN
KDRNINFKENEVMAVVGACHGMYLALQSIINPGEEVIVHSPYFTPYKEQIEMVGGKFIEFETLEEDEFNINPKKLEKLIN
SKTKAIVLNSPNNPTGAFFPKELLKEIAKIAIENDLVVISDEVYDGFTYYEDFCSIASLEGMKERTITLGSFSKDFCMTG
WRVGYVAAPDYIINTMKNINEGICFSAPTISQRAAIYALKNRDNIVDKIKKEFRERMEYAYSRIGSMPKLSAFKPKAGIY
IFANIKETGKSSEEFCDELLNKAHIVAIPGKAFGKYGEGYIRIACTVGLEELEQAFDRIEKIL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=391, Percent_Identity=28.1329923273657, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI169881279, Length=391, Percent_Identity=28.1329923273657, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI56713254, Length=320, Percent_Identity=30.625, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI56713256, Length=320, Percent_Identity=30.625, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI169881281, Length=300, Percent_Identity=29.6666666666667, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI4507369, Length=380, Percent_Identity=25, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI187936925, Length=389, Percent_Identity=24.9357326478149, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI14211921, Length=389, Percent_Identity=24.9357326478149, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1788722, Length=383, Percent_Identity=26.3707571801567, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786816, Length=327, Percent_Identity=22.9357798165138, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788627, Length=292, Percent_Identity=26.3698630136986, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790797, Length=317, Percent_Identity=25.5520504731861, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788332, Length=291, Percent_Identity=22.3367697594502, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=419, Percent_Identity=25.5369928400955, Blast_Score=140, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI17567369, Length=325, Percent_Identity=29.5384615384615, Blast_Score=137, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI71994472, Length=261, Percent_Identity=31.0344827586207, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71994476, Length=261, Percent_Identity=31.0344827586207, Blast_Score=136, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6322401, Length=370, Percent_Identity=28.1081081081081, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28573069, Length=327, Percent_Identity=25.6880733944954, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24646114, Length=327, Percent_Identity=25.6880733944954, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28573067, Length=327, Percent_Identity=25.6880733944954, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28573065, Length=327, Percent_Identity=25.6880733944954, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI18859735, Length=372, Percent_Identity=23.6559139784946, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24641770, Length=346, Percent_Identity=24.8554913294798, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641760, Length=346, Percent_Identity=24.8554913294798, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641768, Length=346, Percent_Identity=24.8554913294798, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641766, Length=346, Percent_Identity=24.8554913294798, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641764, Length=346, Percent_Identity=24.8554913294798, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45551451, Length=346, Percent_Identity=24.8554913294798, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43588; Mature: 43588

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDKFLAHKYKENENNLMSETANLKNKFKDIIDLSLGDPDIITDKSIIKMAFKDTKKGYT
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCC
RYSDPTGDKELIEEIINFYNKDRNINFKENEVMAVVGACHGMYLALQSIINPGEEVIVHS
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
PYFTPYKEQIEMVGGKFIEFETLEEDEFNINPKKLEKLINSKTKAIVLNSPNNPTGAFFP
CCCCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCH
KELLKEIAKIAIENDLVVISDEVYDGFTYYEDFCSIASLEGMKERTITLGSFSKDFCMTG
HHHHHHHHHHHHCCCEEEEECHHHCCHHHHHHHHHHHHHCCCHHHEEEECCCCCHHHHCC
WRVGYVAAPDYIINTMKNINEGICFSAPTISQRAAIYALKNRDNIVDKIKKEFRERMEYA
CEEEEEECCHHHHHHHHHCCCCCEECCCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHH
YSRIGSMPKLSAFKPKAGIYIFANIKETGKSSEEFCDELLNKAHIVAIPGKAFGKYGEGY
HHHHCCCCCCCCCCCCCCEEEEEECHHCCCCHHHHHHHHHCCCEEEEECCHHHCCCCCCE
IRIACTVGLEELEQAFDRIEKIL
EEEEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKDKFLAHKYKENENNLMSETANLKNKFKDIIDLSLGDPDIITDKSIIKMAFKDTKKGYT
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCC
RYSDPTGDKELIEEIINFYNKDRNINFKENEVMAVVGACHGMYLALQSIINPGEEVIVHS
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
PYFTPYKEQIEMVGGKFIEFETLEEDEFNINPKKLEKLINSKTKAIVLNSPNNPTGAFFP
CCCCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCH
KELLKEIAKIAIENDLVVISDEVYDGFTYYEDFCSIASLEGMKERTITLGSFSKDFCMTG
HHHHHHHHHHHHCCCEEEEECHHHCCHHHHHHHHHHHHHCCCHHHEEEECCCCCHHHHCC
WRVGYVAAPDYIINTMKNINEGICFSAPTISQRAAIYALKNRDNIVDKIKKEFRERMEYA
CEEEEEECCHHHHHHHHHCCCCCEECCCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHH
YSRIGSMPKLSAFKPKAGIYIFANIKETGKSSEEFCDELLNKAHIVAIPGKAFGKYGEGY
HHHHCCCCCCCCCCCCCCEEEEEECHHCCCCHHHHHHHHHCCCEEEEECCHHHCCCCCCE
IRIACTVGLEELEQAFDRIEKIL
EEEEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]