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The map label for this gene is yacO [H]

Identifier: 170757788

GI number: 170757788

Start: 3797604

End: 3798377

Strand: Reverse

Name: yacO [H]

Synonym: CLD_1003

Alternate gene names: 170757788

Gene position: 3798377-3797604 (Counterclockwise)

Preceding gene: 170756791

Following gene: 170755536

Centisome position: 95.96

GC content: 31.14

Gene sequence:

>774_bases
ATGAAAAATAGAGTTGGTCAACAGGAAGAAATAAGAGAAGATATAATAGAGGGCAGAAATGCGGTAATAGAAGCATTAAA
ATCAAATAAAACTATAGAAAAGGTAATGGTAGCAAAAGGAGATTTAGAAGGATCTATCAAAATTATAATATCTTTAGCTA
AGGAAAAGGGAATAGTTATAAATGAAGTTGATAGAAAAAAACTTGACTCTATATCCCAAACAAGAGCTCATCAAGGAGTT
ATAGCATTTACAACTCCATATCAATATTGTGCAGTAGAAGATATTATACGATACGCAAAACAAAAAGAAGAGGATCCCTT
TATAATAATATTAGATGAAATAGAAGATCCACACAATTTTGGATCCATATTAAGAACGGCAGAAGTTTGTGGAGCACATG
GTGTCATAATACCTAAGAGAAGAAATGTAGGAGTTACTCCTACTGTCTATAAAACATCTGCTGGAGCCGTAGAATATATG
AAAATAAGTAAGGTTACCAACATAAATAATGTTATAGATAAACTTAAAGAAAAGGGTATATGGATATATGGCGCAGATAT
GTGTGGAAATGATTATTGTTTTGATGTAAATCTATCTGGACCTATAGCATTAGTTATAGGAAGTGAAGGAAGAGGAATAT
CAAAGTTAACTAAAAACAAATGTGATGCTTTAGTTAAAATCCCAATGTTTGGGAATATAACATCTCTTAATGCATCCGTT
GCTGGAGGAATGTTAATGTATGAAATATTAAAACAAAGGATGAAGAGCAAATAA

Upstream 100 bases:

>100_bases
GCGTAAATGGACCTTGTCCAGAAGGAAAAATGTCCTGTGGTAAAATAAGAGAAGTTAGAGAAAAGTACAATGTAAAATTA
TACAAGGAGAGTAAGTAATA

Downstream 100 bases:

>100_bases
TTATGAAATATATATTTGTAGATGCTTATAATGTCATAAATAGTTGGAAAGAATTGAAAAAGATAAAAGACTATAATTTA
GAAATGTCAAGAGAGCAACT

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKNRVGQQEEIREDIIEGRNAVIEALKSNKTIEKVMVAKGDLEGSIKIIISLAKEKGIVINEVDRKKLDSISQTRAHQGV
IAFTTPYQYCAVEDIIRYAKQKEEDPFIIILDEIEDPHNFGSILRTAEVCGAHGVIIPKRRNVGVTPTVYKTSAGAVEYM
KISKVTNINNVIDKLKEKGIWIYGADMCGNDYCFDVNLSGPIALVIGSEGRGISKLTKNKCDALVKIPMFGNITSLNASV
AGGMLMYEILKQRMKSK

Sequences:

>Translated_257_residues
MKNRVGQQEEIREDIIEGRNAVIEALKSNKTIEKVMVAKGDLEGSIKIIISLAKEKGIVINEVDRKKLDSISQTRAHQGV
IAFTTPYQYCAVEDIIRYAKQKEEDPFIIILDEIEDPHNFGSILRTAEVCGAHGVIIPKRRNVGVTPTVYKTSAGAVEYM
KISKVTNINNVIDKLKEKGIWIYGADMCGNDYCFDVNLSGPIALVIGSEGRGISKLTKNKCDALVKIPMFGNITSLNASV
AGGMLMYEILKQRMKSK
>Mature_257_residues
MKNRVGQQEEIREDIIEGRNAVIEALKSNKTIEKVMVAKGDLEGSIKIIISLAKEKGIVINEVDRKKLDSISQTRAHQGV
IAFTTPYQYCAVEDIIRYAKQKEEDPFIIILDEIEDPHNFGSILRTAEVCGAHGVIIPKRRNVGVTPTVYKTSAGAVEYM
KISKVTNINNVIDKLKEKGIWIYGADMCGNDYCFDVNLSGPIALVIGSEGRGISKLTKNKCDALVKIPMFGNITSLNASV
AGGMLMYEILKQRMKSK

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=260, Percent_Identity=26.5384615384615, Blast_Score=115, Evalue=3e-26,
Organism=Escherichia coli, GI1790623, Length=244, Percent_Identity=36.0655737704918, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI1790083, Length=168, Percent_Identity=26.7857142857143, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788935, Length=190, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17555908, Length=267, Percent_Identity=28.0898876404494, Blast_Score=98, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6324775, Length=170, Percent_Identity=33.5294117647059, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 28436; Mature: 28436

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNRVGQQEEIREDIIEGRNAVIEALKSNKTIEKVMVAKGDLEGSIKIIISLAKEKGIVI
CCCCCCCHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEEHHHCCEEE
NEVDRKKLDSISQTRAHQGVIAFTTPYQYCAVEDIIRYAKQKEEDPFIIILDEIEDPHNF
ECCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
GSILRTAEVCGAHGVIIPKRRNVGVTPTVYKTSAGAVEYMKISKVTNINNVIDKLKEKGI
HHHHHHHHHCCCCCEEEECCCCCCCCCEEEECCCCCEEEEHHHHHCCHHHHHHHHHHCCE
WIYGADMCGNDYCFDVNLSGPIALVIGSEGRGISKLTKNKCDALVKIPMFGNITSLNASV
EEEECCCCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHCCEEEEECCCCCEEECCHHH
AGGMLMYEILKQRMKSK
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNRVGQQEEIREDIIEGRNAVIEALKSNKTIEKVMVAKGDLEGSIKIIISLAKEKGIVI
CCCCCCCHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEEHHHCCEEE
NEVDRKKLDSISQTRAHQGVIAFTTPYQYCAVEDIIRYAKQKEEDPFIIILDEIEDPHNF
ECCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
GSILRTAEVCGAHGVIIPKRRNVGVTPTVYKTSAGAVEYMKISKVTNINNVIDKLKEKGI
HHHHHHHHHCCCCCEEEECCCCCCCCCEEEECCCCCEEEEHHHHHCCHHHHHHHHHHCCE
WIYGADMCGNDYCFDVNLSGPIALVIGSEGRGISKLTKNKCDALVKIPMFGNITSLNASV
EEEECCCCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHCCEEEEECCCCCEEECCHHH
AGGMLMYEILKQRMKSK
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]