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The map label for this gene is pgsA

Identifier: 170757752

GI number: 170757752

Start: 2522055

End: 2522639

Strand: Reverse

Name: pgsA

Synonym: CLD_2235

Alternate gene names: 170757752

Gene position: 2522639-2522055 (Counterclockwise)

Preceding gene: 170754856

Following gene: 170755068

Centisome position: 63.73

GC content: 30.43

Gene sequence:

>585_bases
ATGAACTTAGCAAATAAACTAACTATATTAAGAATTTTTTTAGTCCCAATATTTCTTATATTTATATCAGTAAAAAACAT
ACCCTATGGTACAGTAATAGCTACTGCAGTTTTTGTAATAGCTTCAGCTACAGATAAATTAGATGGGTACATAGCCAGAA
GTAGAAATCAAGTTACTAGATTTGGTAAAATAATGGATCCTCTAGCAGATAAAATGTTAGTAACAGCAGCATTAATATCT
TTAGTAGATTTTCAAATAGTACCTGGATGGGCTTGTATAATAATCATAGCCAGAGAATTTGCTGTAACAGGGCTTAGAAG
TGTAGCTTCTGCAGAGGGGGTAGTAATTGCTGCTAGTAAATGGGGAAAGGCTAAGACTGTAATACAAATAGTAGCTATAA
TATTTGCTCTTGTAAATCTAAATTACCAAGAGGGAATATATATATTAGGAAATTGGGCTGTAAATTATATAAATATTATA
GCGAATATAACGAATATTACTATGGCATTGGCTATAATAATAACTATAGTATCTGGTGTAGATTACTTTGTTAAAAATAA
AGATGTAATGAGCCATGATAAGTAG

Upstream 100 bases:

>100_bases
GAAATTTACTTTGAAAAAGATGAAAACGTAAGAATTGGTGATATAATAAAGGTGAAGGTAACTCATAGTTTAGAATATGA
TTTAATAGGAGTTGTTTATA

Downstream 100 bases:

>100_bases
GTTTATAAAAAAATATATTGTCAATAATTTAAATAAAAGTTCCTGTAGGGGGCTTTTATTTATATTATATTAAGTTGACC
CTAGTAAAAAAATAGTATAT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MNLANKLTILRIFLVPIFLIFISVKNIPYGTVIATAVFVIASATDKLDGYIARSRNQVTRFGKIMDPLADKMLVTAALIS
LVDFQIVPGWACIIIIAREFAVTGLRSVASAEGVVIAASKWGKAKTVIQIVAIIFALVNLNYQEGIYILGNWAVNYINII
ANITNITMALAIIITIVSGVDYFVKNKDVMSHDK

Sequences:

>Translated_194_residues
MNLANKLTILRIFLVPIFLIFISVKNIPYGTVIATAVFVIASATDKLDGYIARSRNQVTRFGKIMDPLADKMLVTAALIS
LVDFQIVPGWACIIIIAREFAVTGLRSVASAEGVVIAASKWGKAKTVIQIVAIIFALVNLNYQEGIYILGNWAVNYINII
ANITNITMALAIIITIVSGVDYFVKNKDVMSHDK
>Mature_194_residues
MNLANKLTILRIFLVPIFLIFISVKNIPYGTVIATAVFVIASATDKLDGYIARSRNQVTRFGKIMDPLADKMLVTAALIS
LVDFQIVPGWACIIIIAREFAVTGLRSVASAEGVVIAASKWGKAKTVIQIVAIIFALVNLNYQEGIYILGNWAVNYINII
ANITNITMALAIIITIVSGVDYFVKNKDVMSHDK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=147, Percent_Identity=36.0544217687075, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21204; Mature: 21204

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLANKLTILRIFLVPIFLIFISVKNIPYGTVIATAVFVIASATDKLDGYIARSRNQVTR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGKIMDPLADKMLVTAALISLVDFQIVPGWACIIIIAREFAVTGLRSVASAEGVVIAASK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
WGKAKTVIQIVAIIFALVNLNYQEGIYILGNWAVNYINIIANITNITMALAIIITIVSGV
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DYFVKNKDVMSHDK
HHHHCCCCCCCCCC
>Mature Secondary Structure
MNLANKLTILRIFLVPIFLIFISVKNIPYGTVIATAVFVIASATDKLDGYIARSRNQVTR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGKIMDPLADKMLVTAALISLVDFQIVPGWACIIIIAREFAVTGLRSVASAEGVVIAASK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
WGKAKTVIQIVAIIFALVNLNYQEGIYILGNWAVNYINIIANITNITMALAIIITIVSGV
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DYFVKNKDVMSHDK
HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]