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The map label for this gene is yyaL [H]

Identifier: 170757692

GI number: 170757692

Start: 1180715

End: 1182757

Strand: Direct

Name: yyaL [H]

Synonym: CLD_3500

Alternate gene names: 170757692

Gene position: 1180715-1182757 (Clockwise)

Preceding gene: 170755256

Following gene: 170754824

Centisome position: 29.83

GC content: 28.49

Gene sequence:

>2043_bases
ATGAACCTAACAAGTACGAATAGATTAATGAATGAGAAATCTCCCTATTTACTTCAACACGCTCATAATCCAGTGGATTG
GTATCCTTGGGGGGAAGAAGCTTTTGAAAAAGCAAAGATAGAGGATAAGCCTGTATTTCTAAGTATAGGTTATTCTACCT
GTCATTGGTGCCATGTTATGGAAAGAGAGTCCTTTGAGGATGAGGAAGTTGCGGAAGTTTTAAATAAGAACTTTATTTCT
ATAAAGGTAGATAGAGAAGAAAGACCAGATATAGATAGTATATATATGAATTTTTGTCAGGCTTACACAGGCAGTGGAGG
ATGGCCTTTAACTATACTTATGACTCCAGATAAAAATCCCTTTTTTGCAGGTACTTATTTCCCAAAATGGGGAAAGTACA
ATGTACCTGGAATTATGGATATTTTAAGATCTATAAGTAATCTTTGGAGAGAAGATAAAAATAAAATATTAGAATCCAGT
AATAGAATATTAGAGCAAATAGAAAGATTTCAAGATAATCATAGAGAAGGTGAACTTGAAGAATATATTATTGAAGAAGC
TATCAAAACTCTACTAGATAATTTTGATAATCAATATGGTGGCTTTGGTACATATCCTAAATTTCCTACAGCTCATTATA
TATTATTCTTATTAAGATACTATTATTTTAAAAAGGATAAAAAAATATTAGATATTGTAAATAAGACCTTAACTAGTATG
TATAAAGGTGGAATATTTGATCATATAGGCTTTGGATTTTCAAGATATTCTACAGACAATAAGTGGCTTGTACCTCACTT
TGAAAAGATGCTTTATGATAATGCACTTTTATCTATGGCTTATACAGAAGCTTATGAAGCTACAAAAAATCCACTATTTA
AAGATATAACAGAAAAAATATTAAACTATGTAAAAAAATCCATGACTTCTGACGAAGGTGGGTTTTATTCTGCGGAGGAT
GCAGATTCTGAAGGGGTAGAAGGCAAATTTTATTTATGGACTAAAGAAGAAATAATGGATATTTTAGGTGAGGAAGAAGG
GGAACTTTACTGTAAGATTTATGATATAACATCTAAAGGAAATTTTGAAAATAAAAATATAGCTAATCTTATAAATACAG
ACTTAAAGATTGTAGATAATAATAAAGATAAATTAGAAAAAATGAGGAAAAAGTTATTTGAATACAGAGAAAAAAGAATA
CATCCCTATAAAGATGATAAAATACTAACCTCATGGAATGCTTTAATGATAATAGCTTTTTCTAAGGCTGGCAGAAGTTT
CAAAAATGATAATTATATAGAGATAGCAAAAAAATCAGCAAATTTTATAATAGAAAACCTAATGGATGAAAGAGGCACAT
TATATGCAAGAATTAGAGAGGGAGAAAGAGGTAATGAAGGGTTTATAGATGATTACGCTTTCTTTTTATGGGCACTTATA
GAATTATATGAAGCAAGTTTTGATATTTATTATTTAGAAAAATCTATAGAAGTTGCTGATAGTATGATAGATTTATTCTG
GCATAAAGAAAATGGTGGATTTTACTTATACAGTAAAAATAGTGAAAAACTTTTAGTAAGACCAAAGGAAATCTATGATG
GGGCTACGCCATCAGGAAATGCTGTAGCATCTTTAGCATTGAATCTACTTTACTATATTACAGGAGAGGATAGATATAAA
TATTTGGTGGATAAGCAATTTAAGTTTTTTGCAACAAATATAAAAAGTGGACCAATGTATCACTTATTTTCTGTAATGGC
CTATATGTATAATATTTTACCTGTAAAAGAAATAACATTAGCCTATAGAGAAAAAGATGAAGATTTCTATAAATTTATAA
ATGAACTAAATAATAGATATATACCTTTTTCAATAGTAACCTTAAATGATAAAAGTAATGAAATAGAGAAAATAAATAAA
AATATTAAAGATAAAATTGCTATAAAAGATAAAACTACAGTTTATATATGCCAAAATTACGCCTGCAGAGAACCTATAGC
AGATTTAGAAGAATTTAAATTTTTACTATCTACTGATTCTTAG

Upstream 100 bases:

>100_bases
CTCATCTACTCTTTTTTGTTGCTTTTTTTATTTTAAGGGGAGTTAAAGAAATTTTACTGGGTATACTAATTTTATTAATA
AATTTTAAGAAGGTGTTTTT

Downstream 100 bases:

>100_bases
GGATAGTAAAGAAACACTTACAGAGTATATATTTGAATCATTGAGGTATATGGTTATGATATAAATAAATATAAAAAACA
TACGGGAAGTTATGGTAGAA

Product: hypothetical protein

Products: ADP; dTDP

Alternate protein names: NA

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MNLTSTNRLMNEKSPYLLQHAHNPVDWYPWGEEAFEKAKIEDKPVFLSIGYSTCHWCHVMERESFEDEEVAEVLNKNFIS
IKVDREERPDIDSIYMNFCQAYTGSGGWPLTILMTPDKNPFFAGTYFPKWGKYNVPGIMDILRSISNLWREDKNKILESS
NRILEQIERFQDNHREGELEEYIIEEAIKTLLDNFDNQYGGFGTYPKFPTAHYILFLLRYYYFKKDKKILDIVNKTLTSM
YKGGIFDHIGFGFSRYSTDNKWLVPHFEKMLYDNALLSMAYTEAYEATKNPLFKDITEKILNYVKKSMTSDEGGFYSAED
ADSEGVEGKFYLWTKEEIMDILGEEEGELYCKIYDITSKGNFENKNIANLINTDLKIVDNNKDKLEKMRKKLFEYREKRI
HPYKDDKILTSWNALMIIAFSKAGRSFKNDNYIEIAKKSANFIIENLMDERGTLYARIREGERGNEGFIDDYAFFLWALI
ELYEASFDIYYLEKSIEVADSMIDLFWHKENGGFYLYSKNSEKLLVRPKEIYDGATPSGNAVASLALNLLYYITGEDRYK
YLVDKQFKFFATNIKSGPMYHLFSVMAYMYNILPVKEITLAYREKDEDFYKFINELNNRYIPFSIVTLNDKSNEIEKINK
NIKDKIAIKDKTTVYICQNYACREPIADLEEFKFLLSTDS

Sequences:

>Translated_680_residues
MNLTSTNRLMNEKSPYLLQHAHNPVDWYPWGEEAFEKAKIEDKPVFLSIGYSTCHWCHVMERESFEDEEVAEVLNKNFIS
IKVDREERPDIDSIYMNFCQAYTGSGGWPLTILMTPDKNPFFAGTYFPKWGKYNVPGIMDILRSISNLWREDKNKILESS
NRILEQIERFQDNHREGELEEYIIEEAIKTLLDNFDNQYGGFGTYPKFPTAHYILFLLRYYYFKKDKKILDIVNKTLTSM
YKGGIFDHIGFGFSRYSTDNKWLVPHFEKMLYDNALLSMAYTEAYEATKNPLFKDITEKILNYVKKSMTSDEGGFYSAED
ADSEGVEGKFYLWTKEEIMDILGEEEGELYCKIYDITSKGNFENKNIANLINTDLKIVDNNKDKLEKMRKKLFEYREKRI
HPYKDDKILTSWNALMIIAFSKAGRSFKNDNYIEIAKKSANFIIENLMDERGTLYARIREGERGNEGFIDDYAFFLWALI
ELYEASFDIYYLEKSIEVADSMIDLFWHKENGGFYLYSKNSEKLLVRPKEIYDGATPSGNAVASLALNLLYYITGEDRYK
YLVDKQFKFFATNIKSGPMYHLFSVMAYMYNILPVKEITLAYREKDEDFYKFINELNNRYIPFSIVTLNDKSNEIEKINK
NIKDKIAIKDKTTVYICQNYACREPIADLEEFKFLLSTDS
>Mature_680_residues
MNLTSTNRLMNEKSPYLLQHAHNPVDWYPWGEEAFEKAKIEDKPVFLSIGYSTCHWCHVMERESFEDEEVAEVLNKNFIS
IKVDREERPDIDSIYMNFCQAYTGSGGWPLTILMTPDKNPFFAGTYFPKWGKYNVPGIMDILRSISNLWREDKNKILESS
NRILEQIERFQDNHREGELEEYIIEEAIKTLLDNFDNQYGGFGTYPKFPTAHYILFLLRYYYFKKDKKILDIVNKTLTSM
YKGGIFDHIGFGFSRYSTDNKWLVPHFEKMLYDNALLSMAYTEAYEATKNPLFKDITEKILNYVKKSMTSDEGGFYSAED
ADSEGVEGKFYLWTKEEIMDILGEEEGELYCKIYDITSKGNFENKNIANLINTDLKIVDNNKDKLEKMRKKLFEYREKRI
HPYKDDKILTSWNALMIIAFSKAGRSFKNDNYIEIAKKSANFIIENLMDERGTLYARIREGERGNEGFIDDYAFFLWALI
ELYEASFDIYYLEKSIEVADSMIDLFWHKENGGFYLYSKNSEKLLVRPKEIYDGATPSGNAVASLALNLLYYITGEDRYK
YLVDKQFKFFATNIKSGPMYHLFSVMAYMYNILPVKEITLAYREKDEDFYKFINELNNRYIPFSIVTLNDKSNEIEKINK
NIKDKIAIKDKTTVYICQNYACREPIADLEEFKFLLSTDS

Specific function: Unknown

COG id: COG1331

COG function: function code O; Highly conserved protein containing a thioredoxin domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To C.elegans B0495.5 [H]

Homologues:

Organism=Homo sapiens, GI31542723, Length=723, Percent_Identity=35.6846473029046, Blast_Score=476, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI25147430, Length=726, Percent_Identity=35.5371900826446, Blast_Score=426, Evalue=1e-119,
Organism=Drosophila melanogaster, GI20129985, Length=725, Percent_Identity=38.2068965517241, Blast_Score=478, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008928
- InterPro:   IPR012341
- InterPro:   IPR010819
- InterPro:   IPR004879
- InterPro:   IPR005198
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03190 DUF255; PF07221 GlcNAc_2-epim; PF03663 Glyco_hydro_76 [H]

EC number: 2.7.4.9

Molecular weight: Translated: 79945; Mature: 79945

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTSTNRLMNEKSPYLLQHAHNPVDWYPWGEEAFEKAKIEDKPVFLSIGYSTCHWCHVM
CCCCCHHHHHCCCCCHHHHHCCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCHHHHHHHH
ERESFEDEEVAEVLNKNFISIKVDREERPDIDSIYMNFCQAYTGSGGWPLTILMTPDKNP
HHCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
FFAGTYFPKWGKYNVPGIMDILRSISNLWREDKNKILESSNRILEQIERFQDNHREGELE
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
EYIIEEAIKTLLDNFDNQYGGFGTYPKFPTAHYILFLLRYYYFKKDKKILDIVNKTLTSM
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
YKGGIFDHIGFGFSRYSTDNKWLVPHFEKMLYDNALLSMAYTEAYEATKNPLFKDITEKI
HCCCCHHHHCCCHHEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LNYVKKSMTSDEGGFYSAEDADSEGVEGKFYLWTKEEIMDILGEEEGELYCKIYDITSKG
HHHHHHHCCCCCCCEECCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCEEEEEEEEECCC
NFENKNIANLINTDLKIVDNNKDKLEKMRKKLFEYREKRIHPYKDDKILTSWNALMIIAF
CCCCCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEEEEEEE
SKAGRSFKNDNYIEIAKKSANFIIENLMDERGTLYARIREGERGNEGFIDDYAFFLWALI
ECCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
ELYEASFDIYYLEKSIEVADSMIDLFWHKENGGFYLYSKNSEKLLVRPKEIYDGATPSGN
HHHHCCCEEEEEHHHHHHHHHHHHHHEEECCCCEEEEECCCCEEEECCHHHHCCCCCCCH
AVASLALNLLYYITGEDRYKYLVDKQFKFFATNIKSGPMYHLFSVMAYMYNILPVKEITL
HHHHHHHHHHEEEECCCCEEHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHH
AYREKDEDFYKFINELNNRYIPFSIVTLNDKSNEIEKINKNIKDKIAIKDKTTVYICQNY
HHHCCCHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHCCHHHEEEECCCCEEEEECCC
ACREPIADLEEFKFLLSTDS
CCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLTSTNRLMNEKSPYLLQHAHNPVDWYPWGEEAFEKAKIEDKPVFLSIGYSTCHWCHVM
CCCCCHHHHHCCCCCHHHHHCCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCHHHHHHHH
ERESFEDEEVAEVLNKNFISIKVDREERPDIDSIYMNFCQAYTGSGGWPLTILMTPDKNP
HHCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
FFAGTYFPKWGKYNVPGIMDILRSISNLWREDKNKILESSNRILEQIERFQDNHREGELE
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
EYIIEEAIKTLLDNFDNQYGGFGTYPKFPTAHYILFLLRYYYFKKDKKILDIVNKTLTSM
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
YKGGIFDHIGFGFSRYSTDNKWLVPHFEKMLYDNALLSMAYTEAYEATKNPLFKDITEKI
HCCCCHHHHCCCHHEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LNYVKKSMTSDEGGFYSAEDADSEGVEGKFYLWTKEEIMDILGEEEGELYCKIYDITSKG
HHHHHHHCCCCCCCEECCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCEEEEEEEEECCC
NFENKNIANLINTDLKIVDNNKDKLEKMRKKLFEYREKRIHPYKDDKILTSWNALMIIAF
CCCCCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEEEEEEE
SKAGRSFKNDNYIEIAKKSANFIIENLMDERGTLYARIREGERGNEGFIDDYAFFLWALI
ECCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
ELYEASFDIYYLEKSIEVADSMIDLFWHKENGGFYLYSKNSEKLLVRPKEIYDGATPSGN
HHHHCCCEEEEEHHHHHHHHHHHHHHEEECCCCEEEEECCCCEEEECCHHHHCCCCCCCH
AVASLALNLLYYITGEDRYKYLVDKQFKFFATNIKSGPMYHLFSVMAYMYNILPVKEITL
HHHHHHHHHHEEEECCCCEEHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHH
AYREKDEDFYKFINELNNRYIPFSIVTLNDKSNEIEKINKNIKDKIAIKDKTTVYICQNY
HHHCCCHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHCCHHHEEEECCCCEEEEECCC
ACREPIADLEEFKFLLSTDS
CCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dTMP

Specific reaction: ATP + dTMP = ADP + dTDP

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]