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The map label for this gene is atpA

Identifier: 170757651

GI number: 170757651

Start: 2805247

End: 2807025

Strand: Reverse

Name: atpA

Synonym: CLD_1940

Alternate gene names: 170757651

Gene position: 2807025-2805247 (Counterclockwise)

Preceding gene: 170756616

Following gene: 170754730

Centisome position: 70.92

GC content: 35.92

Gene sequence:

>1779_bases
GTGAACTTGAAGACAGGACGTGTTTTAAAGATATCTGGACCTTTAGTTGTTGCTGAAGGAATGGAAGAGGCAAACATATA
TGACGTTGTAAAAGTTGGTGAAAAACGTCTTATTGGTGAAATAATAGAAATGAGAGAAGATAGAGCTTCAATTCAGGTTT
ACGAAGAAACTGCAGGTTTAGCACCAGGAGACCCAGTAATAACTACTGGGGAACCTTTAAGTGTTGAATTAGGACCTGGG
TTAATAGAAGCCATGTTCGATGGAATACAAAGGCCTTTAAATGCTATAAAAGCGAAGGCTGGAGATTTCATAACAAGAGG
AGTAGAAGTTCATTCATTAGATAGAGATAGAAAATGGCATTTCACTCCACTTAAAAAAGTAGGAGATACTGTAGAAGCAG
GAGATGTAATAGGTATCGTTCAAGAAACTTCTATAGTAGAACATAAAATAATGGTTCCTTATGGTATAAAAGGAACTATA
GAGACTATAGAAGAAGGAGACTTCACTGTAGTTGATACTGTAGCAAAAGTTAAGGATAAAGATAAAGTTTCTGACTTAAT
TATGATGCAAAAATGGCCTGTTAGAAGAGGAAGACCTTATGGTAGAAAGCTTAATCCAGTAGAGCCTATGATAACAGGTC
AAAGAGTTATAGATACATTTTTCCCTGTTACAAAGGGTGGTACAGCATGTGTTCCAGGACCTTTTGGTAGTGGAAAAACT
GTTGTACAACATCAATTGGCTAAATGGGCAGATGCTCAAATAGTTGTTTATATAGGCTGTGGAGAACGTGGTAATGAAAT
GACAGATGTTCTTAATGAATTCCCAGAACTTAAAGACCCTAAAACTGGGGAGCCATTAATGAAAAGAACTGTACTTATAG
CCAATACTTCTAATATGCCCGTTGCAGCTAGAGAAGCTTCTATATATACTGGAATAACTATAGGAGAATACTTTAGAGAT
ATGGGATATTCTGTTGCATTAATGGCAGATTCTACATCCCGTTGGGCAGAAGCTCTTCGTGAAATGTCAGGAAGACTTGA
AGAAATGCCTGGTGATGAAGGTTATCCAGCATACCTAGGATCAAGAGCTGCAGATTTCTATGAAAGAGCAGGTAAGGTAT
TGTCTCTAGGATCTGAGGGAAGAGAAGGAGCACTAACAGTTATAGGGGCTGTATCCCCTCCAGGAGGAGACTTATCAGAA
CCTGTTACCCAAGCAACTTTAAGAATAGTTAAAGTATTCTGGGGGTTAGATTCTCAACTTGCATATAGAAGACATTTCCC
AGCTATAAACTGGTTAAATTCTTATTCATTATATTTGGAGAAAATAAGTCCTTGGATGGATGAAAATGTAGCATCTGATT
GGACAGCACTTAGAACAAGAGCTATGTCACTTCTTCAAGAAGAGGCTAACTTAGAAGAAATAGTTAGACTTGTAGGTATA
GATGCTTTATCTGAAAAAGATAGATTAAAGCTTGAGGTTGCAAAATCTTTAAGAGAAGACTATCTACAACAAAATGCCTT
CCATGAAGTAGATACTTATGCTTCATTAGAAAAGCAATATAAGATGTTAAAGTTAGTTTTATTCTTCTATGATGAAACTC
AAAGAGCATTAAATGCAGGCGTATACTTAAAAGAACTTTTAGACCTAGAAGTTAGGGATAAAATAGCAAGAGCAAAATAT
GTTTCAGAAGAAAGTATAGAAAATATAGACGCAATATTTAATGAATTATCAGAGGTAATAGATGAATTAATTAGCAAAGG
AGGTATAATGAATGCTTAA

Upstream 100 bases:

>100_bases
ATTCCTAGTAATCAGGGCTCTCTAAATATTGGTATGAAGAGAATAAATGATAATGTGGAAAAAGCAGTTGGTGTTAATAT
TTTATAAGGAAGGTAGGTAG

Downstream 100 bases:

>100_bases
GGAATATAGAACAGTTAAAGAAGTAGTTGGACCACTTATGCTGGTTGATCAAGTAGATGGCGTTAGTTTTGATGAACTTG
TTGAAATAGAACTTCATAAC

Product: V-type ATP synthase subunit A

Products: NA

Alternate protein names: V-ATPase subunit A

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MNLKTGRVLKISGPLVVAEGMEEANIYDVVKVGEKRLIGEIIEMREDRASIQVYEETAGLAPGDPVITTGEPLSVELGPG
LIEAMFDGIQRPLNAIKAKAGDFITRGVEVHSLDRDRKWHFTPLKKVGDTVEAGDVIGIVQETSIVEHKIMVPYGIKGTI
ETIEEGDFTVVDTVAKVKDKDKVSDLIMMQKWPVRRGRPYGRKLNPVEPMITGQRVIDTFFPVTKGGTACVPGPFGSGKT
VVQHQLAKWADAQIVVYIGCGERGNEMTDVLNEFPELKDPKTGEPLMKRTVLIANTSNMPVAAREASIYTGITIGEYFRD
MGYSVALMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRAADFYERAGKVLSLGSEGREGALTVIGAVSPPGGDLSE
PVTQATLRIVKVFWGLDSQLAYRRHFPAINWLNSYSLYLEKISPWMDENVASDWTALRTRAMSLLQEEANLEEIVRLVGI
DALSEKDRLKLEVAKSLREDYLQQNAFHEVDTYASLEKQYKMLKLVLFFYDETQRALNAGVYLKELLDLEVRDKIARAKY
VSEESIENIDAIFNELSEVIDELISKGGIMNA

Sequences:

>Translated_592_residues
MNLKTGRVLKISGPLVVAEGMEEANIYDVVKVGEKRLIGEIIEMREDRASIQVYEETAGLAPGDPVITTGEPLSVELGPG
LIEAMFDGIQRPLNAIKAKAGDFITRGVEVHSLDRDRKWHFTPLKKVGDTVEAGDVIGIVQETSIVEHKIMVPYGIKGTI
ETIEEGDFTVVDTVAKVKDKDKVSDLIMMQKWPVRRGRPYGRKLNPVEPMITGQRVIDTFFPVTKGGTACVPGPFGSGKT
VVQHQLAKWADAQIVVYIGCGERGNEMTDVLNEFPELKDPKTGEPLMKRTVLIANTSNMPVAAREASIYTGITIGEYFRD
MGYSVALMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRAADFYERAGKVLSLGSEGREGALTVIGAVSPPGGDLSE
PVTQATLRIVKVFWGLDSQLAYRRHFPAINWLNSYSLYLEKISPWMDENVASDWTALRTRAMSLLQEEANLEEIVRLVGI
DALSEKDRLKLEVAKSLREDYLQQNAFHEVDTYASLEKQYKMLKLVLFFYDETQRALNAGVYLKELLDLEVRDKIARAKY
VSEESIENIDAIFNELSEVIDELISKGGIMNA
>Mature_592_residues
MNLKTGRVLKISGPLVVAEGMEEANIYDVVKVGEKRLIGEIIEMREDRASIQVYEETAGLAPGDPVITTGEPLSVELGPG
LIEAMFDGIQRPLNAIKAKAGDFITRGVEVHSLDRDRKWHFTPLKKVGDTVEAGDVIGIVQETSIVEHKIMVPYGIKGTI
ETIEEGDFTVVDTVAKVKDKDKVSDLIMMQKWPVRRGRPYGRKLNPVEPMITGQRVIDTFFPVTKGGTACVPGPFGSGKT
VVQHQLAKWADAQIVVYIGCGERGNEMTDVLNEFPELKDPKTGEPLMKRTVLIANTSNMPVAAREASIYTGITIGEYFRD
MGYSVALMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRAADFYERAGKVLSLGSEGREGALTVIGAVSPPGGDLSE
PVTQATLRIVKVFWGLDSQLAYRRHFPAINWLNSYSLYLEKISPWMDENVASDWTALRTRAMSLLQEEANLEEIVRLVGI
DALSEKDRLKLEVAKSLREDYLQQNAFHEVDTYASLEKQYKMLKLVLFFYDETQRALNAGVYLKELLDLEVRDKIARAKY
VSEESIENIDAIFNELSEVIDELISKGGIMNA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit

COG id: COG1155

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI19913424, Length=538, Percent_Identity=53.7174721189591, Blast_Score=598, Evalue=1e-171,
Organism=Homo sapiens, GI32189394, Length=315, Percent_Identity=29.5238095238095, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI19913426, Length=241, Percent_Identity=27.8008298755187, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI19913428, Length=241, Percent_Identity=26.9709543568465, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI50345984, Length=237, Percent_Identity=27.8481012658228, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI4757810, Length=237, Percent_Identity=27.8481012658228, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1790170, Length=366, Percent_Identity=28.4153005464481, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788251, Length=326, Percent_Identity=27.6073619631902, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1790172, Length=236, Percent_Identity=26.271186440678, Blast_Score=79, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17565854, Length=540, Percent_Identity=52.2222222222222, Blast_Score=578, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI25144756, Length=335, Percent_Identity=28.6567164179104, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17510931, Length=240, Percent_Identity=28.75, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17570191, Length=241, Percent_Identity=27.8008298755187, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71988074, Length=329, Percent_Identity=25.8358662613982, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71988080, Length=242, Percent_Identity=27.6859504132231, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71988063, Length=242, Percent_Identity=27.6859504132231, Blast_Score=87, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320016, Length=312, Percent_Identity=51.9230769230769, Blast_Score=333, Evalue=4e-92,
Organism=Saccharomyces cerevisiae, GI6322581, Length=330, Percent_Identity=28.4848484848485, Blast_Score=107, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6319603, Length=242, Percent_Identity=29.3388429752066, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319370, Length=236, Percent_Identity=26.6949152542373, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24583988, Length=541, Percent_Identity=53.0499075785582, Blast_Score=594, Evalue=1e-170,
Organism=Drosophila melanogaster, GI24583986, Length=541, Percent_Identity=53.0499075785582, Blast_Score=594, Evalue=1e-170,
Organism=Drosophila melanogaster, GI24583984, Length=541, Percent_Identity=53.0499075785582, Blast_Score=594, Evalue=1e-170,
Organism=Drosophila melanogaster, GI20129479, Length=532, Percent_Identity=52.6315789473684, Blast_Score=585, Evalue=1e-167,
Organism=Drosophila melanogaster, GI24583992, Length=539, Percent_Identity=52.1335807050093, Blast_Score=585, Evalue=1e-167,
Organism=Drosophila melanogaster, GI28574560, Length=302, Percent_Identity=32.1192052980132, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24638766, Length=307, Percent_Identity=29.6416938110749, Blast_Score=113, Evalue=5e-25,
Organism=Drosophila melanogaster, GI281361666, Length=241, Percent_Identity=26.9709543568465, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24646341, Length=241, Percent_Identity=26.9709543568465, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI17136796, Length=241, Percent_Identity=26.9709543568465, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24658560, Length=237, Percent_Identity=27.4261603375527, Blast_Score=83, Evalue=6e-16,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): VATA_CLOBK (B1IJM8)

Other databases:

- EMBL:   CP000939
- RefSeq:   YP_001782240.1
- ProteinModelPortal:   B1IJM8
- SMR:   B1IJM8
- GeneID:   6148501
- GenomeReviews:   CP000939_GR
- KEGG:   cbb:CLD_1940
- HOGENOM:   HBG288114
- OMA:   KITWNVI
- ProtClustDB:   PRK04192
- BioCyc:   CBOT498213:CLD_1940-MONOMER
- HAMAP:   MF_00309
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- InterPro:   IPR022878

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 65754; Mature: 65754

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKTGRVLKISGPLVVAEGMEEANIYDVVKVGEKRLIGEIIEMREDRASIQVYEETAGL
CCCCCCCEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHCCC
APGDPVITTGEPLSVELGPGLIEAMFDGIQRPLNAIKAKAGDFITRGVEVHSLDRDRKWH
CCCCCEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEECCCCCCCC
FTPLKKVGDTVEAGDVIGIVQETSIVEHKIMVPYGIKGTIETIEEGDFTVVDTVAKVKDK
CCHHHHCCCCCCCCCEEEEEHHHHHHHEEEEECCCCCCCHHHHCCCCEEEEHHHHHHCCH
DKVSDLIMMQKWPVRRGRPYGRKLNPVEPMITGQRVIDTFFPVTKGGTACVPGPFGSGKT
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCHH
VVQHQLAKWADAQIVVYIGCGERGNEMTDVLNEFPELKDPKTGEPLMKRTVLIANTSNMP
HHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCHHHHCEEEEEECCCCC
VAAREASIYTGITIGEYFRDMGYSVALMADSTSRWAEALREMSGRLEEMPGDEGYPAYLG
EEECCCCEEECCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCHHHC
SRAADFYERAGKVLSLGSEGREGALTVIGAVSPPGGDLSEPVTQATLRIVKVFWGLDSQL
CHHHHHHHHCCCEEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHH
AYRRHFPAINWLNSYSLYLEKISPWMDENVASDWTALRTRAMSLLQEEANLEEIVRLVGI
HHHHCCCCHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
DALSEKDRLKLEVAKSLREDYLQQNAFHEVDTYASLEKQYKMLKLVLFFYDETQRALNAG
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYLKELLDLEVRDKIARAKYVSEESIENIDAIFNELSEVIDELISKGGIMNA
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNLKTGRVLKISGPLVVAEGMEEANIYDVVKVGEKRLIGEIIEMREDRASIQVYEETAGL
CCCCCCCEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHCCC
APGDPVITTGEPLSVELGPGLIEAMFDGIQRPLNAIKAKAGDFITRGVEVHSLDRDRKWH
CCCCCEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEECCCCCCCC
FTPLKKVGDTVEAGDVIGIVQETSIVEHKIMVPYGIKGTIETIEEGDFTVVDTVAKVKDK
CCHHHHCCCCCCCCCEEEEEHHHHHHHEEEEECCCCCCCHHHHCCCCEEEEHHHHHHCCH
DKVSDLIMMQKWPVRRGRPYGRKLNPVEPMITGQRVIDTFFPVTKGGTACVPGPFGSGKT
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCHH
VVQHQLAKWADAQIVVYIGCGERGNEMTDVLNEFPELKDPKTGEPLMKRTVLIANTSNMP
HHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCHHHHCEEEEEECCCCC
VAAREASIYTGITIGEYFRDMGYSVALMADSTSRWAEALREMSGRLEEMPGDEGYPAYLG
EEECCCCEEECCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCHHHC
SRAADFYERAGKVLSLGSEGREGALTVIGAVSPPGGDLSEPVTQATLRIVKVFWGLDSQL
CHHHHHHHHCCCEEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHH
AYRRHFPAINWLNSYSLYLEKISPWMDENVASDWTALRTRAMSLLQEEANLEEIVRLVGI
HHHHCCCCHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
DALSEKDRLKLEVAKSLREDYLQQNAFHEVDTYASLEKQYKMLKLVLFFYDETQRALNAG
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYLKELLDLEVRDKIARAKYVSEESIENIDAIFNELSEVIDELISKGGIMNA
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA