Click here to switch to the map view.

The map label for this gene is yycG [H]

Identifier: 170757581

GI number: 170757581

Start: 1244899

End: 1246332

Strand: Direct

Name: yycG [H]

Synonym: CLD_3441

Alternate gene names: 170757581

Gene position: 1244899-1246332 (Clockwise)

Preceding gene: 170756781

Following gene: 170755611

Centisome position: 31.45

GC content: 21.41

Gene sequence:

>1434_bases
ATGGAAAATATAAGTACTGTAATTATTAGAGAACGACAGGAAGTTATAAAGAAATTTTTACCCATAAGATTTATATTAAT
TAACGTAGTAATTGGTTTTATTTATGTAAGTTATGTTAAATCAGATTTAAAATCTTTTTGTATTTTTAATATTGCAATGG
TAGAGGGAATAATATTCAATAATATGTTGTATGGATTTTCTAGTAGAGATATGAAAACTTTTAAAAACAAATTTAATAGT
AAGTATAATAATAAAACAAAAATATATAAAAATTTTATTAATAATATTATTTCACCTATAATAATATTAAAAGATGAAAA
AATTTATTTTATGAATGATGAAGCTAAAAAATTTATAAAAATTAAAAAGAATATAAATTTTAATAATATAAATATATATG
ATTATTTAGAAGAAAAATTTTATAAAGAAGGATTATTAAAAATAGATAATATCAAAAATTCTACAGGAATTACCTATTTA
AATGAAAAAATTATTTTAAAAAATGGAGAAATATTAAAGGTGGATTTAAGATGCTTTGTTTTAGACTTAAATGACGAAGA
GTTTGTAAGTATATCTATTAAGAACAATGTCTTATTACAAGAAAATAAAAAATTATATGGAGAGCTAGAAAAAAACAAAG
TAGAACATAGACAAAGAGCTGAATTTTATGCTAATATATCACATGATTTAAAAACACCTATAAATATTATATATTCTGCT
ATTCAGGTTATGAATATGGCTTTAGACAATAAAAAAATAGATACTATTGAAAAATATATTGGAGTAATAAAACAAAATTG
TTACAGACTTTTAAGACTTGTAAATAATATAGTTAACACCAATAAGATTGAATCCGGATGTTGTAAAATTAAATTAAATA
ATAATAATATAGTTAGTTTAGTTGAAGACATAGTTACATCTGTTTCTACATATGTTGAGAATAATGATATGAATATAATA
TTTGATACAGATACAGAAGAAAAAATTATAGCTTGTGATAAGGATATGATAGAAAGAGTTGTATTAAATCTTATATCAAA
TTCTGTTAAATATAAACAAAGCGGAAAAGGAAGTATACAAGTTACTGTACAAGATAAAGAGGATAGAGTTATTGTTTCTG
TTAAAGATAATGGTATAGGAATACCTAAAAATATACAAAAGAATGTGTTTAATAGATTTGTACAATCAAATAGAAAAGAA
TATGATTTAACAACTTGTAGTAGTGGTATAGGACTTGCTTTAGTTAAATCTATAATTGATATGCATGATGGAAATATTCA
AATAAACAGTAGAGAAAATAAAGGCACAGAGATAATCTTTGAACTTCCTTCTAGGAAGGTTAAAGAAAATGAGAAATGTA
AGGAAATATATACTAAAAATATAGGAAAGAATGTAAAAATTGAATTTCCAGAAATATATGATAGTGCTATTTGA

Upstream 100 bases:

>100_bases
TATTTTAAATTTTAAAACCAATAAAAGGAAAATAATAGAAAATGTTGAATTATTTATATATAAAGTAAAATTATGCATAT
ATTAAAAGGGGAGTGGGGAA

Downstream 100 bases:

>100_bases
ATAAAGACTTTAAAAGAGTTGTTTTTAGTGATAAAGAGGGCGTTTCAAAATTAAATATATTTTGAAACACCTTCCTTTTA
TTATCTTATCATGTAAATTG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MENISTVIIRERQEVIKKFLPIRFILINVVIGFIYVSYVKSDLKSFCIFNIAMVEGIIFNNMLYGFSSRDMKTFKNKFNS
KYNNKTKIYKNFINNIISPIIILKDEKIYFMNDEAKKFIKIKKNINFNNINIYDYLEEKFYKEGLLKIDNIKNSTGITYL
NEKIILKNGEILKVDLRCFVLDLNDEEFVSISIKNNVLLQENKKLYGELEKNKVEHRQRAEFYANISHDLKTPINIIYSA
IQVMNMALDNKKIDTIEKYIGVIKQNCYRLLRLVNNIVNTNKIESGCCKIKLNNNNIVSLVEDIVTSVSTYVENNDMNII
FDTDTEEKIIACDKDMIERVVLNLISNSVKYKQSGKGSIQVTVQDKEDRVIVSVKDNGIGIPKNIQKNVFNRFVQSNRKE
YDLTTCSSGIGLALVKSIIDMHDGNIQINSRENKGTEIIFELPSRKVKENEKCKEIYTKNIGKNVKIEFPEIYDSAI

Sequences:

>Translated_477_residues
MENISTVIIRERQEVIKKFLPIRFILINVVIGFIYVSYVKSDLKSFCIFNIAMVEGIIFNNMLYGFSSRDMKTFKNKFNS
KYNNKTKIYKNFINNIISPIIILKDEKIYFMNDEAKKFIKIKKNINFNNINIYDYLEEKFYKEGLLKIDNIKNSTGITYL
NEKIILKNGEILKVDLRCFVLDLNDEEFVSISIKNNVLLQENKKLYGELEKNKVEHRQRAEFYANISHDLKTPINIIYSA
IQVMNMALDNKKIDTIEKYIGVIKQNCYRLLRLVNNIVNTNKIESGCCKIKLNNNNIVSLVEDIVTSVSTYVENNDMNII
FDTDTEEKIIACDKDMIERVVLNLISNSVKYKQSGKGSIQVTVQDKEDRVIVSVKDNGIGIPKNIQKNVFNRFVQSNRKE
YDLTTCSSGIGLALVKSIIDMHDGNIQINSRENKGTEIIFELPSRKVKENEKCKEIYTKNIGKNVKIEFPEIYDSAI
>Mature_477_residues
MENISTVIIRERQEVIKKFLPIRFILINVVIGFIYVSYVKSDLKSFCIFNIAMVEGIIFNNMLYGFSSRDMKTFKNKFNS
KYNNKTKIYKNFINNIISPIIILKDEKIYFMNDEAKKFIKIKKNINFNNINIYDYLEEKFYKEGLLKIDNIKNSTGITYL
NEKIILKNGEILKVDLRCFVLDLNDEEFVSISIKNNVLLQENKKLYGELEKNKVEHRQRAEFYANISHDLKTPINIIYSA
IQVMNMALDNKKIDTIEKYIGVIKQNCYRLLRLVNNIVNTNKIESGCCKIKLNNNNIVSLVEDIVTSVSTYVENNDMNII
FDTDTEEKIIACDKDMIERVVLNLISNSVKYKQSGKGSIQVTVQDKEDRVIVSVKDNGIGIPKNIQKNVFNRFVQSNRKE
YDLTTCSSGIGLALVKSIIDMHDGNIQINSRENKGTEIIFELPSRKVKENEKCKEIYTKNIGKNVKIEFPEIYDSAI

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=238, Percent_Identity=26.4705882352941, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=27.8969957081545, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1790300, Length=288, Percent_Identity=25.6944444444444, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI48994928, Length=253, Percent_Identity=26.0869565217391, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789149, Length=242, Percent_Identity=23.1404958677686, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788393, Length=250, Percent_Identity=22.8, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788549, Length=227, Percent_Identity=25.5506607929515, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788713, Length=244, Percent_Identity=24.1803278688525, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789808, Length=237, Percent_Identity=24.8945147679325, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=23.3870967741935, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081816, Length=257, Percent_Identity=24.124513618677, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082128, Length=234, Percent_Identity=23.9316239316239, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786783, Length=230, Percent_Identity=25.2173913043478, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790436, Length=226, Percent_Identity=23.4513274336283, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55319; Mature: 55319

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENISTVIIRERQEVIKKFLPIRFILINVVIGFIYVSYVKSDLKSFCIFNIAMVEGIIFN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NMLYGFSSRDMKTFKNKFNSKYNNKTKIYKNFINNIISPIIILKDEKIYFMNDEAKKFIK
HHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCEEEEECCHHHHHHH
IKKNINFNNINIYDYLEEKFYKEGLLKIDNIKNSTGITYLNEKIILKNGEILKVDLRCFV
HCCCCCCCCEEHHHHHHHHHHHCCCEEEECCCCCCCEEEECCEEEEECCCEEEEEEEEEE
LDLNDEEFVSISIKNNVLLQENKKLYGELEKNKVEHRQRAEFYANISHDLKTPINIIYSA
EECCCCCEEEEEEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
IQVMNMALDNKKIDTIEKYIGVIKQNCYRLLRLVNNIVNTNKIESGCCKIKLNNNNIVSL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHH
VEDIVTSVSTYVENNDMNIIFDTDTEEKIIACDKDMIERVVLNLISNSVKYKQSGKGSIQ
HHHHHHHHHHHEECCCCEEEEECCCCCCEEECCHHHHHHHHHHHHHCCCEECCCCCCEEE
VTVQDKEDRVIVSVKDNGIGIPKNIQKNVFNRFVQSNRKEYDLTTCSSGIGLALVKSIID
EEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHH
MHDGNIQINSRENKGTEIIFELPSRKVKENEKCKEIYTKNIGKNVKIEFPEIYDSAI
CCCCCEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEECHHHHCCCC
>Mature Secondary Structure
MENISTVIIRERQEVIKKFLPIRFILINVVIGFIYVSYVKSDLKSFCIFNIAMVEGIIFN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NMLYGFSSRDMKTFKNKFNSKYNNKTKIYKNFINNIISPIIILKDEKIYFMNDEAKKFIK
HHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCEEEEECCHHHHHHH
IKKNINFNNINIYDYLEEKFYKEGLLKIDNIKNSTGITYLNEKIILKNGEILKVDLRCFV
HCCCCCCCCEEHHHHHHHHHHHCCCEEEECCCCCCCEEEECCEEEEECCCEEEEEEEEEE
LDLNDEEFVSISIKNNVLLQENKKLYGELEKNKVEHRQRAEFYANISHDLKTPINIIYSA
EECCCCCEEEEEEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
IQVMNMALDNKKIDTIEKYIGVIKQNCYRLLRLVNNIVNTNKIESGCCKIKLNNNNIVSL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHH
VEDIVTSVSTYVENNDMNIIFDTDTEEKIIACDKDMIERVVLNLISNSVKYKQSGKGSIQ
HHHHHHHHHHHEECCCCEEEEECCCCCCEEECCHHHHHHHHHHHHHCCCEECCCCCCEEE
VTVQDKEDRVIVSVKDNGIGIPKNIQKNVFNRFVQSNRKEYDLTTCSSGIGLALVKSIID
EEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHH
MHDGNIQINSRENKGTEIIFELPSRKVKENEKCKEIYTKNIGKNVKIEFPEIYDSAI
CCCCCEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEECHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]