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The map label for this gene is lytT [H]

Identifier: 170757477

GI number: 170757477

Start: 748315

End: 749331

Strand: Direct

Name: lytT [H]

Synonym: CLD_0132

Alternate gene names: 170757477

Gene position: 748315-749331 (Clockwise)

Preceding gene: 170757463

Following gene: 170755433

Centisome position: 18.91

GC content: 27.83

Gene sequence:

>1017_bases
ATGCTAAAAATTAAAGGTTTATACAAAGAGCAAAAAAATAATGTAATAAAAGATATAGACATTGATATAAATAAAGGTAG
TTCTATAAGTATAGAGTGCAGCAATGAGATAAGTGATTTACTGATAAATTTAATTTTAGGAAGAGATATGCCAGCAAAGG
GTGAAATATGCCTAGAAAATATAAAACATTTAGATTATATTAAGACTAATATTAGTAATATTGGGGTTGTACTTAGAGAA
GAGAGCTTTTACGATAGAATGACTATAGAGGAGTACATGAAGTTTTTTTTTAGTCTTTTGTCTTCAAAGGTAGATTATAA
AGAGATAATGCTAAAACTTGCATTACTAGACATTGGGAATAAAAAAATAAAAGATTTAAACTATTCTCAGAAAAGAAGAT
TAAGCTTTGCAAGAGAGAGATTAAAACAGCCCAGATTTTTAATATTTCAGGAGCCAATTCTTAATATGGATAGAGATGGA
GCTAAAGTGATAATAGAAAATATAGAGGATTTAAAGTCTAATGGAACTGCTATTTTAATTACATCCGTGGTATTTAAAGA
TACACTTATGCTTAGTGAAAAGGCTTATAGATTAAATGATGAGGGATTAGTAGAGTTAGATAACAGCTTAGAGGAATCTA
AAAATGAGAGAGAAGAGGTTTTAGATAAAAAACCAGTATATAAAATAGAAAAAATTCCTGCCAAATTAGATGAAAGAATT
TTATTATTTGATCCTATAGATATTGATTACATAGAAAGCCAACAGGGAGTTAGTAATTTAACCATTAGAGGGGACAAGTT
TCCTTGTACTATTTCTCTTACTGATCTAGAGGAGAGATTAAAATATTTTGGATTTTTTAGATGTCATAGATCCTATTTAG
TAAATTTGCAAAGAGTGAAGGAAGTAATTACTTGGACAAGAAATAGTTACACTTTAAGTTTAGATGATAAAGTAAAGAGT
TCTATTCCTTTGTCTAAAAGAAGATTAGAGGAACTAAAGGATATATTAAATCTATAA

Upstream 100 bases:

>100_bases
TAAATCCTATAGGCTTTGGTTAGATATTTACAAAGTATCCTAAGTTGTGTTATTCCTTTTATGATAAAATAAGGATATGA
AAAGCGGAAGGATGTTTTAT

Downstream 100 bases:

>100_bases
AAATTATATTAAAATTTAACTCATGATATTGAGAAGGCTAAAAATATTAAATTCAGATTATGAAATTATATTAAGATTTA
AAATGTAAATTTTATATTAA

Product: LytR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MLKIKGLYKEQKNNVIKDIDIDINKGSSISIECSNEISDLLINLILGRDMPAKGEICLENIKHLDYIKTNISNIGVVLRE
ESFYDRMTIEEYMKFFFSLLSSKVDYKEIMLKLALLDIGNKKIKDLNYSQKRRLSFARERLKQPRFLIFQEPILNMDRDG
AKVIIENIEDLKSNGTAILITSVVFKDTLMLSEKAYRLNDEGLVELDNSLEESKNEREEVLDKKPVYKIEKIPAKLDERI
LLFDPIDIDYIESQQGVSNLTIRGDKFPCTISLTDLEERLKYFGFFRCHRSYLVNLQRVKEVITWTRNSYTLSLDDKVKS
SIPLSKRRLEELKDILNL

Sequences:

>Translated_338_residues
MLKIKGLYKEQKNNVIKDIDIDINKGSSISIECSNEISDLLINLILGRDMPAKGEICLENIKHLDYIKTNISNIGVVLRE
ESFYDRMTIEEYMKFFFSLLSSKVDYKEIMLKLALLDIGNKKIKDLNYSQKRRLSFARERLKQPRFLIFQEPILNMDRDG
AKVIIENIEDLKSNGTAILITSVVFKDTLMLSEKAYRLNDEGLVELDNSLEESKNEREEVLDKKPVYKIEKIPAKLDERI
LLFDPIDIDYIESQQGVSNLTIRGDKFPCTISLTDLEERLKYFGFFRCHRSYLVNLQRVKEVITWTRNSYTLSLDDKVKS
SIPLSKRRLEELKDILNL
>Mature_338_residues
MLKIKGLYKEQKNNVIKDIDIDINKGSSISIECSNEISDLLINLILGRDMPAKGEICLENIKHLDYIKTNISNIGVVLRE
ESFYDRMTIEEYMKFFFSLLSSKVDYKEIMLKLALLDIGNKKIKDLNYSQKRRLSFARERLKQPRFLIFQEPILNMDRDG
AKVIIENIEDLKSNGTAILITSVVFKDTLMLSEKAYRLNDEGLVELDNSLEESKNEREEVLDKKPVYKIEKIPAKLDERI
LLFDPIDIDYIESQQGVSNLTIRGDKFPCTISLTDLEERLKYFGFFRCHRSYLVNLQRVKEVITWTRNSYTLSLDDKVKS
SIPLSKRRLEELKDILNL

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=102, Percent_Identity=31.3725490196078, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 39437; Mature: 39437

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS50930 HTH_LYTTR ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIKGLYKEQKNNVIKDIDIDINKGSSISIECSNEISDLLINLILGRDMPAKGEICLEN
CCEECCHHHHHHCCCEEEEEEEECCCCEEEEEECHHHHHHHHHHHHCCCCCCCCHHHHHH
IKHLDYIKTNISNIGVVLREESFYDRMTIEEYMKFFFSLLSSKVDYKEIMLKLALLDIGN
HHHHHHHHHCHHHCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
KKIKDLNYSQKRRLSFARERLKQPRFLIFQEPILNMDRDGAKVIIENIEDLKSNGTAILI
CHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
TSVVFKDTLMLSEKAYRLNDEGLVELDNSLEESKNEREEVLDKKPVYKIEKIPAKLDERI
EHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHCCEE
LLFDPIDIDYIESQQGVSNLTIRGDKFPCTISLTDLEERLKYFGFFRCHRSYLVNLQRVK
EEECCCCCCCCCCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVITWTRNSYTLSLDDKVKSSIPLSKRRLEELKDILNL
HHHHHCCCCEEEEECHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKIKGLYKEQKNNVIKDIDIDINKGSSISIECSNEISDLLINLILGRDMPAKGEICLEN
CCEECCHHHHHHCCCEEEEEEEECCCCEEEEEECHHHHHHHHHHHHCCCCCCCCHHHHHH
IKHLDYIKTNISNIGVVLREESFYDRMTIEEYMKFFFSLLSSKVDYKEIMLKLALLDIGN
HHHHHHHHHCHHHCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
KKIKDLNYSQKRRLSFARERLKQPRFLIFQEPILNMDRDGAKVIIENIEDLKSNGTAILI
CHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
TSVVFKDTLMLSEKAYRLNDEGLVELDNSLEESKNEREEVLDKKPVYKIEKIPAKLDERI
EHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHCCEE
LLFDPIDIDYIESQQGVSNLTIRGDKFPCTISLTDLEERLKYFGFFRCHRSYLVNLQRVK
EEECCCCCCCCCCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVITWTRNSYTLSLDDKVKSSIPLSKRRLEELKDILNL
HHHHHCCCCEEEEECHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]