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The map label for this gene is fabH

Identifier: 170757452

GI number: 170757452

Start: 3917739

End: 3918719

Strand: Reverse

Name: fabH

Synonym: CLD_0882

Alternate gene names: 170757452

Gene position: 3918719-3917739 (Counterclockwise)

Preceding gene: 170755066

Following gene: 170756859

Centisome position: 99.0

GC content: 30.38

Gene sequence:

>981_bases
ATGAGTAATATTAGTGTTATTGGAACTGGAAGTTATGTACCTAATAATATTATTACTAATGATTTTTTATCAACTATAGT
AGATACTAGCGATGAATGGATAAGAACTAGAACAGGTATATTAGAGAGAAGGATTTCTAAGGGAGAAAACACTATTTATA
TGGCAACAGAATCTGCAAAAGAAGCAATTAAAAATGCTAATATAGAGGCTAATGATTTAGATTTAATAATTGTAGCTACA
TTGACTCCAGACAATTTTATGCCTTCTACTGCCTGTAGTGTTCAAAAGGAAATAGGAGCTATAAACGCTTTATGCTTTGA
CATATCTGCAGCTTGTTCAGGGTTTATATATGGACTTGAGATAGCCTGTTCTATGTTAAAAAATAGCTTTAGAAATAAAG
CTTTAATAATAGGTGCTGAGAATCTATCTAAAATAGTTGACTGGGAAGATAGAAATACCTGTGTATTGTTTGGAGATGGA
GCAGGGGCAGCTATATTAAGTAAAACTAAGGAAGAAGGAATTTTAGAGTTCCATTCTAGATCAAATGGATTAAAAGGAGA
ACATCTTACTTGTGGAGCCTTAGAAGCAAATAATATTTTTAATAAAGATGATATGCTAAAAAATAATAAATTTATAAAGA
TGAATGGTAAAGAAATATTTAGATTTGCTGTAGGAGCAATGAGTGAAACTATTTATAGTATACAAGAAAAAACTAAATGG
GATTTAAGTGAAGTTAAGTATATTATATCTCACCAGGCTAACTCTAGAATAATAGAATACACAGCTAAAAAGCTTAATAC
TAACAAAGATAAATTTTACATGAATCTAGACAAATATGGGAATACATCCGCAGCAAGTATACCTATAGCCTTAGATGAAA
TGAACAAAAAAGGCCTGTTAAATAAACAAGATAAGATTATATTAGTAGGATTTGGTGGTGGCTTAACCTTTGGTGGAGTT
GCTATCTTATGGAGTATTTAA

Upstream 100 bases:

>100_bases
ACAGAAGAAGAAGAAAAAGTACTTATAAAATCTTTGGATAAACTAAATAACTTTTTTAAGGAAAAGTATAATTTAAATAA
AGTTAATAAGGAGAAAAATG

Downstream 100 bases:

>100_bases
TAAAAAATAAAATAAATATAAATTTAGGAGGAAAAGATTATGGTATTTGAAAAGGTTAAAAACATTATAGTAGAACAATT
AGGTTTAGATGAGGGAGAAG

Product: 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSNISVIGTGSYVPNNIITNDFLSTIVDTSDEWIRTRTGILERRISKGENTIYMATESAKEAIKNANIEANDLDLIIVAT
LTPDNFMPSTACSVQKEIGAINALCFDISAACSGFIYGLEIACSMLKNSFRNKALIIGAENLSKIVDWEDRNTCVLFGDG
AGAAILSKTKEEGILEFHSRSNGLKGEHLTCGALEANNIFNKDDMLKNNKFIKMNGKEIFRFAVGAMSETIYSIQEKTKW
DLSEVKYIISHQANSRIIEYTAKKLNTNKDKFYMNLDKYGNTSAASIPIALDEMNKKGLLNKQDKIILVGFGGGLTFGGV
AILWSI

Sequences:

>Translated_326_residues
MSNISVIGTGSYVPNNIITNDFLSTIVDTSDEWIRTRTGILERRISKGENTIYMATESAKEAIKNANIEANDLDLIIVAT
LTPDNFMPSTACSVQKEIGAINALCFDISAACSGFIYGLEIACSMLKNSFRNKALIIGAENLSKIVDWEDRNTCVLFGDG
AGAAILSKTKEEGILEFHSRSNGLKGEHLTCGALEANNIFNKDDMLKNNKFIKMNGKEIFRFAVGAMSETIYSIQEKTKW
DLSEVKYIISHQANSRIIEYTAKKLNTNKDKFYMNLDKYGNTSAASIPIALDEMNKKGLLNKQDKIILVGFGGGLTFGGV
AILWSI
>Mature_325_residues
SNISVIGTGSYVPNNIITNDFLSTIVDTSDEWIRTRTGILERRISKGENTIYMATESAKEAIKNANIEANDLDLIIVATL
TPDNFMPSTACSVQKEIGAINALCFDISAACSGFIYGLEIACSMLKNSFRNKALIIGAENLSKIVDWEDRNTCVLFGDGA
GAAILSKTKEEGILEFHSRSNGLKGEHLTCGALEANNIFNKDDMLKNNKFIKMNGKEIFRFAVGAMSETIYSIQEKTKWD
LSEVKYIISHQANSRIIEYTAKKLNTNKDKFYMNLDKYGNTSAASIPIALDEMNKKGLLNKQDKIILVGFGGGLTFGGVA
ILWSI

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=315, Percent_Identity=40.9523809523809, Blast_Score=246, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 35847; Mature: 35716

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNISVIGTGSYVPNNIITNDFLSTIVDTSDEWIRTRTGILERRISKGENTIYMATESAK
CCCEEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHH
EAIKNANIEANDLDLIIVATLTPDNFMPSTACSVQKEIGAINALCFDISAACSGFIYGLE
HHHHCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IACSMLKNSFRNKALIIGAENLSKIVDWEDRNTCVLFGDGAGAAILSKTKEEGILEFHSR
HHHHHHHHHCCCCEEEEECCHHHHHCCCCCCCEEEEEECCCCCHHHHHCCCCCCEEECCC
SNGLKGEHLTCGALEANNIFNKDDMLKNNKFIKMNGKEIFRFAVGAMSETIYSIQEKTKW
CCCCCCCCEEEEEEECCCCCCCCHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCC
DLSEVKYIISHQANSRIIEYTAKKLNTNKDKFYMNLDKYGNTSAASIPIALDEMNKKGLL
CHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCC
NKQDKIILVGFGGGLTFGGVAILWSI
CCCCCEEEEEECCCCCCCCEEEEEEC
>Mature Secondary Structure 
SNISVIGTGSYVPNNIITNDFLSTIVDTSDEWIRTRTGILERRISKGENTIYMATESAK
CCEEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHH
EAIKNANIEANDLDLIIVATLTPDNFMPSTACSVQKEIGAINALCFDISAACSGFIYGLE
HHHHCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IACSMLKNSFRNKALIIGAENLSKIVDWEDRNTCVLFGDGAGAAILSKTKEEGILEFHSR
HHHHHHHHHCCCCEEEEECCHHHHHCCCCCCCEEEEEECCCCCHHHHHCCCCCCEEECCC
SNGLKGEHLTCGALEANNIFNKDDMLKNNKFIKMNGKEIFRFAVGAMSETIYSIQEKTKW
CCCCCCCCEEEEEEECCCCCCCCHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCC
DLSEVKYIISHQANSRIIEYTAKKLNTNKDKFYMNLDKYGNTSAASIPIALDEMNKKGLL
CHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCC
NKQDKIILVGFGGGLTFGGVAILWSI
CCCCCEEEEEECCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA