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The map label for this gene is fhuG

Identifier: 170757399

GI number: 170757399

Start: 807317

End: 808357

Strand: Direct

Name: fhuG

Synonym: CLD_0078

Alternate gene names: 170757399

Gene position: 807317-808357 (Clockwise)

Preceding gene: 170756160

Following gene: 170754335

Centisome position: 20.4

GC content: 36.7

Gene sequence:

>1041_bases
ATGAAAGAACAACAACAAATAATTGAAGCATATAAGCGTAAGGTAGCTATTCGTAATACATTAATTGTAATTGGGTGTGT
TTTATTACTGGCAATTTCTTTAATTGTAAGTATGGATACAGGATATATTAAAATGTCTCCATTTGATGTGTTAAGGACAC
TATTTGGTAAAGGTACAGATAAAGAAAAGTTAATTTTATTTGATTTTAGGCTACCTCGTATAGTTATTTCAATGCTAGTG
GGATCTGGACTTGCTTTATCAGGATGCATAATACAGAGTGTATCTAAAAACCCTCTAGCTGATCCAGGAATTTTAGGCAT
TAACGCTGGTACTAGTTTAATGGTGATTCTGTATGTACTGATTTTTAGTGCTGAATCTTTCCTATCTGTGTTTACTCTTC
CTTTTTTAGCGTTAATAGGGGCAGGCATTACAGCCGTTATAGTCTATATTTTTTCTTATAAACGAGATGAAGGTATCTCA
ACTATGAGGCTTGTTTTAACTGGTGTAGCAGTACAGGCAGGAATTTCAGCATTGACCACTTTACTGGTGGTGAAATTGGA
TGATACACAGTATAACTTTGTGGTTGCTTGGCAGGCAGGAAGTATTTGGGGTTCTAACTGGAAGTTTGTGATGACATTAC
TGCCTTGGCTAGCTATATTGATTCCATATATACTAACAAAATCTTCTGTTATGGACATGCTAAATCTTAGTGATGATATA
GCCTATGGTCTCGGCGTTTCAGTAGAAAAAGAACGTCGCAAACTGCTTGCAGCGGCAGTAGCTCTTGCTGCCTCATGTGT
GGCAGTTAGTGGAAGCATTAGTTTTGTTGGTCTTATAGCACCCCATTTAGCAAGACGACTTGTTGGACCACGTCATCGAG
TACTTTTATCTACTAGTATACTGGTTGGTGCAGTATTAGTATCTCTAGCAGATACTATTGGACGTGTTATCATTCAACCT
TCTGAGATTCCAACAGGAATTGTAGTAGCTATTATTGGAGCGCCATATTTTCTTTATCTTCTTTCTAATAGTAAGAGTTA
A

Upstream 100 bases:

>100_bases
CTTTAAACCCTCCCTTTGAAACTCCCATAGGAGCTATAATTTCTCTCATAGGTGTGCCATTATTTCTAAACTTGGCTCGT
AGGCAAAGGAGTGCAATGTA

Downstream 100 bases:

>100_bases
TCATAGGTTTGTTAATAAAAATAAATATAATATGCAAAAATTTTAATGATATTAAATGTGTTTGAGTAAATCAAATTTGC
AGAAATTCTAATGATGTTAA

Product: ferrichrome ABC transporter, permease protein FhuG

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKEQQQIIEAYKRKVAIRNTLIVIGCVLLLAISLIVSMDTGYIKMSPFDVLRTLFGKGTDKEKLILFDFRLPRIVISMLV
GSGLALSGCIIQSVSKNPLADPGILGINAGTSLMVILYVLIFSAESFLSVFTLPFLALIGAGITAVIVYIFSYKRDEGIS
TMRLVLTGVAVQAGISALTTLLVVKLDDTQYNFVVAWQAGSIWGSNWKFVMTLLPWLAILIPYILTKSSVMDMLNLSDDI
AYGLGVSVEKERRKLLAAAVALAASCVAVSGSISFVGLIAPHLARRLVGPRHRVLLSTSILVGAVLVSLADTIGRVIIQP
SEIPTGIVVAIIGAPYFLYLLSNSKS

Sequences:

>Translated_346_residues
MKEQQQIIEAYKRKVAIRNTLIVIGCVLLLAISLIVSMDTGYIKMSPFDVLRTLFGKGTDKEKLILFDFRLPRIVISMLV
GSGLALSGCIIQSVSKNPLADPGILGINAGTSLMVILYVLIFSAESFLSVFTLPFLALIGAGITAVIVYIFSYKRDEGIS
TMRLVLTGVAVQAGISALTTLLVVKLDDTQYNFVVAWQAGSIWGSNWKFVMTLLPWLAILIPYILTKSSVMDMLNLSDDI
AYGLGVSVEKERRKLLAAAVALAASCVAVSGSISFVGLIAPHLARRLVGPRHRVLLSTSILVGAVLVSLADTIGRVIIQP
SEIPTGIVVAIIGAPYFLYLLSNSKS
>Mature_346_residues
MKEQQQIIEAYKRKVAIRNTLIVIGCVLLLAISLIVSMDTGYIKMSPFDVLRTLFGKGTDKEKLILFDFRLPRIVISMLV
GSGLALSGCIIQSVSKNPLADPGILGINAGTSLMVILYVLIFSAESFLSVFTLPFLALIGAGITAVIVYIFSYKRDEGIS
TMRLVLTGVAVQAGISALTTLLVVKLDDTQYNFVVAWQAGSIWGSNWKFVMTLLPWLAILIPYILTKSSVMDMLNLSDDI
AYGLGVSVEKERRKLLAAAVALAASCVAVSGSISFVGLIAPHLARRLVGPRHRVLLSTSILVGAVLVSLADTIGRVIIQP
SEIPTGIVVAIIGAPYFLYLLSNSKS

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=326, Percent_Identity=38.0368098159509, Blast_Score=187, Evalue=9e-49,
Organism=Escherichia coli, GI1790741, Length=303, Percent_Identity=33.003300330033, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786804, Length=330, Percent_Identity=30.9090909090909, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786805, Length=328, Percent_Identity=34.4512195121951, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1788004, Length=283, Percent_Identity=34.6289752650177, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786347, Length=284, Percent_Identity=32.7464788732394, Blast_Score=125, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37233; Mature: 37233

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEQQQIIEAYKRKVAIRNTLIVIGCVLLLAISLIVSMDTGYIKMSPFDVLRTLFGKGTD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCC
KEKLILFDFRLPRIVISMLVGSGLALSGCIIQSVSKNPLADPGILGINAGTSLMVILYVL
CCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHH
IFSAESFLSVFTLPFLALIGAGITAVIVYIFSYKRDEGISTMRLVLTGVAVQAGISALTT
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLVVKLDDTQYNFVVAWQAGSIWGSNWKFVMTLLPWLAILIPYILTKSSVMDMLNLSDDI
HHEEEECCCCEEEEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AYGLGVSVEKERRKLLAAAVALAASCVAVSGSISFVGLIAPHLARRLVGPRHRVLLSTSI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LVGAVLVSLADTIGRVIIQPSEIPTGIVVAIIGAPYFLYLLSNSKS
HHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHCCCEEEEECCCCC
>Mature Secondary Structure
MKEQQQIIEAYKRKVAIRNTLIVIGCVLLLAISLIVSMDTGYIKMSPFDVLRTLFGKGTD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCC
KEKLILFDFRLPRIVISMLVGSGLALSGCIIQSVSKNPLADPGILGINAGTSLMVILYVL
CCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHH
IFSAESFLSVFTLPFLALIGAGITAVIVYIFSYKRDEGISTMRLVLTGVAVQAGISALTT
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLVVKLDDTQYNFVVAWQAGSIWGSNWKFVMTLLPWLAILIPYILTKSSVMDMLNLSDDI
HHEEEECCCCEEEEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AYGLGVSVEKERRKLLAAAVALAASCVAVSGSISFVGLIAPHLARRLVGPRHRVLLSTSI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LVGAVLVSLADTIGRVIIQPSEIPTGIVVAIIGAPYFLYLLSNSKS
HHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]