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The map label for this gene is ygfU [H]

Identifier: 170757398

GI number: 170757398

Start: 3129016

End: 3130422

Strand: Reverse

Name: ygfU [H]

Synonym: CLD_1655

Alternate gene names: 170757398

Gene position: 3130422-3129016 (Counterclockwise)

Preceding gene: 170756788

Following gene: 170754286

Centisome position: 79.09

GC content: 33.33

Gene sequence:

>1407_bases
ATGGATAATAAAGTAAATAAAGCAATAGCTCCTGTTGACGAAGTACTTCCACCACAGCAGTTATTTATTTTAGGTTTACA
ACATGTATTGGCAATGTGTGCAGGTGCGGTTGCTGTTCCTCTAATAGTAGGTGGTGCACTAAATTTGTCTGCAGAACAGA
CAATATTTCTTATAAATGCAGATCTTTTTGTAGCAGGTATAGCAACGCTAGTACAATCTCTAGGGATAAAAAATTTTATT
GGGGCAAAAGTTCCTGTTATTGAAGGTGCAAGTTTTGCGTCTGTATCGGCCATGATAGCTATTGCAAATACTTATCCAGG
GGATCCTATTACAGCTATTACAACTATTTTTGGAGCTACCTTTGTAGCTGGGTTATTTTGTTTTATTATGGCACCTTTCT
TCGGAAAGCTTATAAGATTTTTCCCTAAGGTAGTAACAGGTACTGTAATAACTATAATAGGCATCTCATTGCTTCCAGTA
GCAGTGAGATGGTGTGCGGGCAATGATGTAAATTCTTCTAAATTTGCTAGCCCTAAAAATATTTTATTAGCTTTGTTTGT
TTTAATTCTAATTTTAATTATGTATAAATTTTTCAAAGGAATTTTAGGAAATATATCTATACTATTAGGGATAGTTGTAG
GAACTATTGTTGCTTCAATGTTAGGAATGTCAGATTTTAGTAGAGTTCATAGTTCAGGATGGATTAATATAGATATTCCC
TTATATTTTGGTGCTCTTAAATTTAATTTGACAGCTATAATTTCAATGATATTAGTTATGTTAGTTATGATGACAGAAGC
TACAGGAAATATGATAGCTATACATGAAATGGTTGGAAAGGATATTGATGATAAAAATTTAACTAGAGGTCTTAGAACAG
ATGGGTTTGCTACAATGCTTGCAGGTATATTTAATACATTCCCTCATACTGCTTTTGGCCAAAATGTAGGTCTCGTAAAT
TTGACAGGTATAAAGAGTCGTTTCGTAGTAGCAGCTTCAGGAGGAATTCTAATATTATTAGGATTATTTCCAAAAGCAGG
AGCAGTAGTTGCGTCTATACCATATCCTGTCCTTGGTGGCGCTGGTATAGCCATGTTTGGTATGGTAACTTCAGGGGGTA
TTTCAAGTCTTAGTAAGGTTGAATTTAATGGAACTAAAAATGGAATGATAATAGCAGTAAGTATTGGCCTTGCTATGATT
CCTTTAGCAGTACCAACTTTTTATAGTAAATTTCCACAATGGGTGGAAACTCTTTTCCACAGCGGCATAACAACTGGTAG
TTTAACAGCAATACTTTTAAATTTATTCTTTAATGAACTTGGAAAGAATAAAAATTTATCAGTAAAAGACGATAAAGAAA
ATAGCTATAAAGTAGAAGTAGCTGATAAAGAAACAAAAAATATATAA

Upstream 100 bases:

>100_bases
ACTTTTATTTAGTACTGAAGGTGACACAGACCCAGATAAATATAGAAAAATTGTTTGGAATGGTGAATATTCAAAATAAA
AAATTCATGGGGGTATAAAA

Downstream 100 bases:

>100_bases
GTTTAAAATCATTTTTCACAATATTCACAAAAGGAGATGCGATTTTAAGATGGCCACTTTAATAAAAAATGGAATTATTG
TTACTTCAGGAGATACCTTT

Product: xanthine/uracil permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MDNKVNKAIAPVDEVLPPQQLFILGLQHVLAMCAGAVAVPLIVGGALNLSAEQTIFLINADLFVAGIATLVQSLGIKNFI
GAKVPVIEGASFASVSAMIAIANTYPGDPITAITTIFGATFVAGLFCFIMAPFFGKLIRFFPKVVTGTVITIIGISLLPV
AVRWCAGNDVNSSKFASPKNILLALFVLILILIMYKFFKGILGNISILLGIVVGTIVASMLGMSDFSRVHSSGWINIDIP
LYFGALKFNLTAIISMILVMLVMMTEATGNMIAIHEMVGKDIDDKNLTRGLRTDGFATMLAGIFNTFPHTAFGQNVGLVN
LTGIKSRFVVAASGGILILLGLFPKAGAVVASIPYPVLGGAGIAMFGMVTSGGISSLSKVEFNGTKNGMIIAVSIGLAMI
PLAVPTFYSKFPQWVETLFHSGITTGSLTAILLNLFFNELGKNKNLSVKDDKENSYKVEVADKETKNI

Sequences:

>Translated_468_residues
MDNKVNKAIAPVDEVLPPQQLFILGLQHVLAMCAGAVAVPLIVGGALNLSAEQTIFLINADLFVAGIATLVQSLGIKNFI
GAKVPVIEGASFASVSAMIAIANTYPGDPITAITTIFGATFVAGLFCFIMAPFFGKLIRFFPKVVTGTVITIIGISLLPV
AVRWCAGNDVNSSKFASPKNILLALFVLILILIMYKFFKGILGNISILLGIVVGTIVASMLGMSDFSRVHSSGWINIDIP
LYFGALKFNLTAIISMILVMLVMMTEATGNMIAIHEMVGKDIDDKNLTRGLRTDGFATMLAGIFNTFPHTAFGQNVGLVN
LTGIKSRFVVAASGGILILLGLFPKAGAVVASIPYPVLGGAGIAMFGMVTSGGISSLSKVEFNGTKNGMIIAVSIGLAMI
PLAVPTFYSKFPQWVETLFHSGITTGSLTAILLNLFFNELGKNKNLSVKDDKENSYKVEVADKETKNI
>Mature_468_residues
MDNKVNKAIAPVDEVLPPQQLFILGLQHVLAMCAGAVAVPLIVGGALNLSAEQTIFLINADLFVAGIATLVQSLGIKNFI
GAKVPVIEGASFASVSAMIAIANTYPGDPITAITTIFGATFVAGLFCFIMAPFFGKLIRFFPKVVTGTVITIIGISLLPV
AVRWCAGNDVNSSKFASPKNILLALFVLILILIMYKFFKGILGNISILLGIVVGTIVASMLGMSDFSRVHSSGWINIDIP
LYFGALKFNLTAIISMILVMLVMMTEATGNMIAIHEMVGKDIDDKNLTRGLRTDGFATMLAGIFNTFPHTAFGQNVGLVN
LTGIKSRFVVAASGGILILLGLFPKAGAVVASIPYPVLGGAGIAMFGMVTSGGISSLSKVEFNGTKNGMIIAVSIGLAMI
PLAVPTFYSKFPQWVETLFHSGITTGSLTAILLNLFFNELGKNKNLSVKDDKENSYKVEVADKETKNI

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680145, Length=441, Percent_Identity=25.8503401360544, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI44680143, Length=444, Percent_Identity=24.3243243243243, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI44680148, Length=181, Percent_Identity=25.9668508287293, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI40316845, Length=181, Percent_Identity=25.9668508287293, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI87082181, Length=455, Percent_Identity=42.4175824175824, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1790087, Length=432, Percent_Identity=31.4814814814815, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI87082178, Length=447, Percent_Identity=29.5302013422819, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI87081818, Length=445, Percent_Identity=29.2134831460674, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI1788843, Length=389, Percent_Identity=28.0205655526992, Blast_Score=122, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71993493, Length=464, Percent_Identity=26.2931034482759, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17542262, Length=450, Percent_Identity=22.4444444444444, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17541904, Length=442, Percent_Identity=23.3031674208145, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17542260, Length=235, Percent_Identity=28.0851063829787, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17558856, Length=217, Percent_Identity=25.3456221198157, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356175, Length=451, Percent_Identity=25.0554323725055, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 49536; Mature: 49536

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNKVNKAIAPVDEVLPPQQLFILGLQHVLAMCAGAVAVPLIVGGALNLSAEQTIFLINA
CCCCHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
DLFVAGIATLVQSLGIKNFIGAKVPVIEGASFASVSAMIAIANTYPGDPITAITTIFGAT
HHHHHHHHHHHHHCCCHHHCCCCCCEECCCCHHHHHHHEEEECCCCCCHHHHHHHHHHHH
FVAGLFCFIMAPFFGKLIRFFPKVVTGTVITIIGISLLPVAVRWCAGNDVNSSKFASPKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
ILLALFVLILILIMYKFFKGILGNISILLGIVVGTIVASMLGMSDFSRVHSSGWINIDIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEHH
LYFGALKFNLTAIISMILVMLVMMTEATGNMIAIHEMVGKDIDDKNLTRGLRTDGFATML
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCHHHHHCCCCCCHHHHHH
AGIFNTFPHTAFGQNVGLVNLTGIKSRFVVAASGGILILLGLFPKAGAVVASIPYPVLGG
HHHHHHCCCCCCCCCCCEEEEECCCCEEEEEECCCEEEEEECCCCCCCEEEECCCCCCCC
AGIAMFGMVTSGGISSLSKVEFNGTKNGMIIAVSIGLAMIPLAVPTFYSKFPQWVETLFH
CHHHHHHHHHCCCCCHHHEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
SGITTGSLTAILLNLFFNELGKNKNLSVKDDKENSYKVEVADKETKNI
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MDNKVNKAIAPVDEVLPPQQLFILGLQHVLAMCAGAVAVPLIVGGALNLSAEQTIFLINA
CCCCHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
DLFVAGIATLVQSLGIKNFIGAKVPVIEGASFASVSAMIAIANTYPGDPITAITTIFGAT
HHHHHHHHHHHHHCCCHHHCCCCCCEECCCCHHHHHHHEEEECCCCCCHHHHHHHHHHHH
FVAGLFCFIMAPFFGKLIRFFPKVVTGTVITIIGISLLPVAVRWCAGNDVNSSKFASPKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
ILLALFVLILILIMYKFFKGILGNISILLGIVVGTIVASMLGMSDFSRVHSSGWINIDIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEHH
LYFGALKFNLTAIISMILVMLVMMTEATGNMIAIHEMVGKDIDDKNLTRGLRTDGFATML
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCHHHHHCCCCCCHHHHHH
AGIFNTFPHTAFGQNVGLVNLTGIKSRFVVAASGGILILLGLFPKAGAVVASIPYPVLGG
HHHHHHCCCCCCCCCCCEEEEECCCCEEEEEECCCEEEEEECCCCCCCEEEECCCCCCCC
AGIAMFGMVTSGGISSLSKVEFNGTKNGMIIAVSIGLAMIPLAVPTFYSKFPQWVETLFH
CHHHHHHHHHCCCCCHHHEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
SGITTGSLTAILLNLFFNELGKNKNLSVKDDKENSYKVEVADKETKNI
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]