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The map label for this gene is ntpI [H]

Identifier: 170757384

GI number: 170757384

Start: 2809483

End: 2811429

Strand: Reverse

Name: ntpI [H]

Synonym: CLD_1935

Alternate gene names: 170757384

Gene position: 2811429-2809483 (Counterclockwise)

Preceding gene: 170755444

Following gene: 170754714

Centisome position: 71.03

GC content: 29.22

Gene sequence:

>1947_bases
ATGAAAAAATTTACTTTATTAGCCCTTGAATCACATAAGGAATCTCTTTTTGAAGCTATGCAAAAGTTTCAAGAAGTACA
GTTTGTTAACCTACAAGAAGAAAAGTCAGAAAAGTTAGAGTTTATGCAAAATGACTCTCAGTCAGAGTTGGTATCAGACT
TAGAAGGTAAACAAGCTAAACTTAAATTTTGTTTAGATATTTTAGAAAGGTATGTACAAAAAGAAAAGGGACTCAAGGCT
CTTATGAAGGGTAAAAAATTCATGGATTATAATGAGCTTAAAAATTTAGGTGAGAATATAGAGTGGATTAGTATTTATAA
TACTTTAAGAGAAAAGGATACAAAACTTAATGCCTTAAAAAATGAAATATCTAAACCAAAAGGTGAAATAAAAGCATTGG
AGCCTTGGATTAATTTTGATGAAAAAATTAGTAAGGCTAAATTTAATACTAGTACTTCTTATTTAGGGGTATTACCTTTA
AATTACAAAGATGAGTTTAGAGAGACTTTTGACTCAGAGATACCAGTTTCTTATGTAGAAACTATAGGGGAAAATAAAGA
TGGAGTTTATTTGTTTGTAGTATTTCATAATGATTACTTTAAAGAAACTTCGGAAGTATTAAAAAGGTATGGTTTTAGTA
AAGTAGCTTTTAACTATGATGATTCTCCTAAAGAAACTATAAAAGCTTTAGAAGAAGAAATAAAGTCTATTAAAAAAGAA
GAAATAAAAACTATAGAAGGAATAAAAGTATTTACTAATAAATTAGAAGATCTTCAAATAGCTTATGAGTATATTAGTTT
ACAGGTTGACAGAGAAAAAGCATCTATGAATATCTTAAAAACAGATAGAATAGTGGCTATGGAAGGTTGGGTACCAGAGG
AATCTATGGAAGAATTAGAAGGCTTAATAAGACAATCCGAAGGTAAGTTATATTATATAGAATTTAATGATCCTTTAGAT
GAAGAAGAAGAAAAGGTTCCAATAATGTTAAAGAACAATAAGATAGTTGAGCCTTTTGAATCTATTACAGCTATGTATAG
CCTTCCGAAGTATAAAGAAATAGATCCTACACCAGCTTTAGTACCTTTTTATTTAATATTCTTTGGAATGATGTTATCGG
ATGCAGGTTATGGTTTAGTTATGCTTATATGTACTTTACTAGCTCTTAAAACTATACCAATGGAAAAAGCAACTAAACAA
ATGATTAAGTTATTATATTACTTAAGTTATCCAACCATAGTTTGGGGCGCGCTTTATGGCAGTTATTTTGGAGGTATTAT
AAACATACCGGCTATATGGGTAAAACCAGAAGATAGTGTATCATCAATTTTAATTATATCTATAGTTTTTGGTATAATTC
ACCTATACACAGGACTTGGTGTAAAAGCTTATATGTTAATTAGAAACAAAAGATATAAAGATGCATTTTACGATGTAGGT
TTATGGTATATAACTTTAACTACAGCTATAATTATAGTAGCTGCAAATTTCGGAAATATAACTGCATTAAATCCATACAC
AAACCCTTGTAAATATATAATGTATGTAGGTATGGTAGGTTTAGTTTTAACTCAAGGTAGAGAAAACAAAACAATAGGAG
CAAAACTTGGTGCAGGTTTATATGGATTATATGGTATTACAAGTTATGTAGGAGATATAGTTTCTTATTCAAGGCTTATG
GCTTTGGGGCTTGCTACAGGATTTATAGGTGGAGCTTTTAACTTAATGATAAGCCTTTTAGGTAATGGAGTTAAAGCATG
GATATTTGGAACATTAATATTTGTTATAGGTCACGTGTTTAATTTGCTTATAAATGCATTAGGTGCTTATGTTCACACTT
GTAGATTACAGTATGTTGAATATTTCGGTAAGTTTTATGAAGGGGGAGGAAAACCATTTACTCCTTTCAAACCAAATAAT
AAATACATTAACATAATAAAAGATTAG

Upstream 100 bases:

>100_bases
AAATCCTTAGAAAGTATAAAAAATATTTCTAAGGATAAATTTGAAAAGGCTACAAATATAGTGATTGAGAGGATAGTGAA
AGTTAATGGGAATAGCTAAG

Downstream 100 bases:

>100_bases
GAGGAGTCTATTATGGAAAATATAACATTAATGAATTTTTTAACACAAAACGGAGGAGCAATATTTGCTGCTATGGGGGT
AGCATTAGCGGCTATAATGC

Product: V-type ATP synthase subunit I

Products: ADP; phosphate; H+

Alternate protein names: Na(+)-translocating ATPase subunit I; V-type sodium pump subunit I [H]

Number of amino acids: Translated: 648; Mature: 648

Protein sequence:

>648_residues
MKKFTLLALESHKESLFEAMQKFQEVQFVNLQEEKSEKLEFMQNDSQSELVSDLEGKQAKLKFCLDILERYVQKEKGLKA
LMKGKKFMDYNELKNLGENIEWISIYNTLREKDTKLNALKNEISKPKGEIKALEPWINFDEKISKAKFNTSTSYLGVLPL
NYKDEFRETFDSEIPVSYVETIGENKDGVYLFVVFHNDYFKETSEVLKRYGFSKVAFNYDDSPKETIKALEEEIKSIKKE
EIKTIEGIKVFTNKLEDLQIAYEYISLQVDREKASMNILKTDRIVAMEGWVPEESMEELEGLIRQSEGKLYYIEFNDPLD
EEEEKVPIMLKNNKIVEPFESITAMYSLPKYKEIDPTPALVPFYLIFFGMMLSDAGYGLVMLICTLLALKTIPMEKATKQ
MIKLLYYLSYPTIVWGALYGSYFGGIINIPAIWVKPEDSVSSILIISIVFGIIHLYTGLGVKAYMLIRNKRYKDAFYDVG
LWYITLTTAIIIVAANFGNITALNPYTNPCKYIMYVGMVGLVLTQGRENKTIGAKLGAGLYGLYGITSYVGDIVSYSRLM
ALGLATGFIGGAFNLMISLLGNGVKAWIFGTLIFVIGHVFNLLINALGAYVHTCRLQYVEYFGKFYEGGGKPFTPFKPNN
KYINIIKD

Sequences:

>Translated_648_residues
MKKFTLLALESHKESLFEAMQKFQEVQFVNLQEEKSEKLEFMQNDSQSELVSDLEGKQAKLKFCLDILERYVQKEKGLKA
LMKGKKFMDYNELKNLGENIEWISIYNTLREKDTKLNALKNEISKPKGEIKALEPWINFDEKISKAKFNTSTSYLGVLPL
NYKDEFRETFDSEIPVSYVETIGENKDGVYLFVVFHNDYFKETSEVLKRYGFSKVAFNYDDSPKETIKALEEEIKSIKKE
EIKTIEGIKVFTNKLEDLQIAYEYISLQVDREKASMNILKTDRIVAMEGWVPEESMEELEGLIRQSEGKLYYIEFNDPLD
EEEEKVPIMLKNNKIVEPFESITAMYSLPKYKEIDPTPALVPFYLIFFGMMLSDAGYGLVMLICTLLALKTIPMEKATKQ
MIKLLYYLSYPTIVWGALYGSYFGGIINIPAIWVKPEDSVSSILIISIVFGIIHLYTGLGVKAYMLIRNKRYKDAFYDVG
LWYITLTTAIIIVAANFGNITALNPYTNPCKYIMYVGMVGLVLTQGRENKTIGAKLGAGLYGLYGITSYVGDIVSYSRLM
ALGLATGFIGGAFNLMISLLGNGVKAWIFGTLIFVIGHVFNLLINALGAYVHTCRLQYVEYFGKFYEGGGKPFTPFKPNN
KYINIIKD
>Mature_648_residues
MKKFTLLALESHKESLFEAMQKFQEVQFVNLQEEKSEKLEFMQNDSQSELVSDLEGKQAKLKFCLDILERYVQKEKGLKA
LMKGKKFMDYNELKNLGENIEWISIYNTLREKDTKLNALKNEISKPKGEIKALEPWINFDEKISKAKFNTSTSYLGVLPL
NYKDEFRETFDSEIPVSYVETIGENKDGVYLFVVFHNDYFKETSEVLKRYGFSKVAFNYDDSPKETIKALEEEIKSIKKE
EIKTIEGIKVFTNKLEDLQIAYEYISLQVDREKASMNILKTDRIVAMEGWVPEESMEELEGLIRQSEGKLYYIEFNDPLD
EEEEKVPIMLKNNKIVEPFESITAMYSLPKYKEIDPTPALVPFYLIFFGMMLSDAGYGLVMLICTLLALKTIPMEKATKQ
MIKLLYYLSYPTIVWGALYGSYFGGIINIPAIWVKPEDSVSSILIISIVFGIIHLYTGLGVKAYMLIRNKRYKDAFYDVG
LWYITLTTAIIIVAANFGNITALNPYTNPCKYIMYVGMVGLVLTQGRENKTIGAKLGAGLYGLYGITSYVGDIVSYSRLM
ALGLATGFIGGAFNLMISLLGNGVKAWIFGTLIFVIGHVFNLLINALGAYVHTCRLQYVEYFGKFYEGGGKPFTPFKPNN
KYINIIKD

Specific function: Involved in ATP-driven sodium extrusion [H]

COG id: COG1269

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase 116 kDa subunit family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002490 [H]

Pfam domain/function: PF01496 V_ATPase_I [H]

EC number: 3.6.3.14

Molecular weight: Translated: 73990; Mature: 73990

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFTLLALESHKESLFEAMQKFQEVQFVNLQEEKSEKLEFMQNDSQSELVSDLEGKQAK
CCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHCCCCHHH
LKFCLDILERYVQKEKGLKALMKGKKFMDYNELKNLGENIEWISIYNTLREKDTKLNALK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
NEISKPKGEIKALEPWINFDEKISKAKFNTSTSYLGVLPLNYKDEFRETFDSEIPVSYVE
HHHCCCCCCCEEECHHCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHCCCCCCHHHHH
TIGENKDGVYLFVVFHNDYFKETSEVLKRYGFSKVAFNYDDSPKETIKALEEEIKSIKKE
HHCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
EIKTIEGIKVFTNKLEDLQIAYEYISLQVDREKASMNILKTDRIVAMEGWVPEESMEELE
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHEEECCCEEEEECCCCHHHHHHHH
GLIRQSEGKLYYIEFNDPLDEEEEKVPIMLKNNKIVEPFESITAMYSLPKYKEIDPTPAL
HHHHCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCH
VPFYLIFFGMMLSDAGYGLVMLICTLLALKTIPMEKATKQMIKLLYYLSYPTIVWGALYG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHH
SYFGGIINIPAIWVKPEDSVSSILIISIVFGIIHLYTGLGVKAYMLIRNKRYKDAFYDVG
HHCCCCEECCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHEEHHHHCCCHHHHHHHHH
LWYITLTTAIIIVAANFGNITALNPYTNPCKYIMYVGMVGLVLTQGRENKTIGAKLGAGL
HHHHHHHHHHHHEEECCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCH
YGLYGITSYVGDIVSYSRLMALGLATGFIGGAFNLMISLLGNGVKAWIFGTLIFVIGHVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
NLLINALGAYVHTCRLQYVEYFGKFYEGGGKPFTPFKPNNKYINIIKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECC
>Mature Secondary Structure
MKKFTLLALESHKESLFEAMQKFQEVQFVNLQEEKSEKLEFMQNDSQSELVSDLEGKQAK
CCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHCCCCHHH
LKFCLDILERYVQKEKGLKALMKGKKFMDYNELKNLGENIEWISIYNTLREKDTKLNALK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
NEISKPKGEIKALEPWINFDEKISKAKFNTSTSYLGVLPLNYKDEFRETFDSEIPVSYVE
HHHCCCCCCCEEECHHCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHCCCCCCHHHHH
TIGENKDGVYLFVVFHNDYFKETSEVLKRYGFSKVAFNYDDSPKETIKALEEEIKSIKKE
HHCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
EIKTIEGIKVFTNKLEDLQIAYEYISLQVDREKASMNILKTDRIVAMEGWVPEESMEELE
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHEEECCCEEEEECCCCHHHHHHHH
GLIRQSEGKLYYIEFNDPLDEEEEKVPIMLKNNKIVEPFESITAMYSLPKYKEIDPTPAL
HHHHCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCH
VPFYLIFFGMMLSDAGYGLVMLICTLLALKTIPMEKATKQMIKLLYYLSYPTIVWGALYG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHH
SYFGGIINIPAIWVKPEDSVSSILIISIVFGIIHLYTGLGVKAYMLIRNKRYKDAFYDVG
HHCCCCEECCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHEEHHHHCCCHHHHHHHHH
LWYITLTTAIIIVAANFGNITALNPYTNPCKYIMYVGMVGLVLTQGRENKTIGAKLGAGL
HHHHHHHHHHHHEEECCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCH
YGLYGITSYVGDIVSYSRLMALGLATGFIGGAFNLMISLLGNGVKAWIFGTLIFVIGHVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
NLLINALGAYVHTCRLQYVEYFGKFYEGGGKPFTPFKPNNKYINIIKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8157629; 8144530 [H]