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The map label for this gene is gntP

Identifier: 170757129

GI number: 170757129

Start: 2398599

End: 2399987

Strand: Reverse

Name: gntP

Synonym: CLD_2371

Alternate gene names: 170757129

Gene position: 2399987-2398599 (Counterclockwise)

Preceding gene: 170757705

Following gene: 170754212

Centisome position: 60.63

GC content: 33.48

Gene sequence:

>1389_bases
ATGGGAAACACAGTAGCAGGAAATCAAATGATATTAGGACTTGTAGTTGGAATTAGCATACTTGTATTCTTAATATTAAA
AACAAAAATTCACACATTCTTAGCACTAATTATCTCGGCAGCTACTACTGGGCTTGTAGGAGGAATGCCACCTAATAAAA
TAATTGATTCAATATCTAAAGGTTTTGGGGGAACTTTAGGAAGCATTGGTATAATCATAGGTTTTGGAGTAATGATGGGC
CAGATTTTTGAAGTATCTGGTGCAGCTGAAAGGATGGCTAGAACTTTTATAAAGTTTTTAGGTAAAAAAAGAGAAGAATT
AGCATTAGCAATAACAGGGTTTATAGTGTCTATACCTATATTTTGTGATTCAGGATTTATAATTCTAGCACCGCTTGCAA
AAGCAATTTCTAAGAAAACTAAAAAATCGGTAGTTTCTTTAGGAGTAGCTTTAGGATTAGGGCTTGTAATTACTCATAGT
TTAGTACCACCAACACCTGGTCCTGTAGGGGTTGCAGGTATATTCGGAGTAAGTGTAGGAAAATTTATTTTATGGGGAAT
TCCTTTAGCTATACCTATGGTGATAGCTGGTATGTTTTATGGAAAGTATATAGGGAAAAAAATATATCAAATTCCAGGAG
ATGAAGAAGATCAGTGGATTAGAACAGAATATCAAGAGCCAGTATATGATTTTGAACATGAAGAGGATAATAAAGAACTA
CCATCTACATTTATGGCTTTTGCACCAATAATGACACCAATAATATTTATACTTATAAACACTATACTAGATGTTTTAAT
CAAACAAAAGACAATAACTCCTAGTGGATTTACTAATATGATTCAATTCTTAGGTTCTCCAATAATTGCAGTAGGAATCG
GTCTTATAATAGCCATATATGGACTAGCAGGTAAGCTAAATAAAGAAGAAGTTATAAATGAAATGGAAAAAGGAATAAAA
TCTGCAGGTATAATAATATTAGTTACTGGTGGCGGTGGAGCTTTAGGTATGGTACTTCGTGATAGTGGTACAGGAGATTA
TATAGCAAAATCAATTGCAGGATCTCATATGCCAGTTGTGTTAATACCATTTATAATAGCATCTTTAGTAAGACTTATCC
AAGGAAGTGGAACAGTTGCTATGATAACTGCGGCTTCTATAACAGCACCAATTGTTGCAGCATCAAATGTTAATCCAATA
TTAGCAGCCCTTGGAGCATGTATGGGATCACTTTTATTCTCATATTTCAATGATAGTTATTTCTGGGTAGTTAACCGCTC
CCTTGGAATAAAAGATGCAAAAGAACAAATAAAAGTATGGTCAGTTACTACTACTATAGCTTGGGCAGTAGGCTTAGTAG
AACTAATTATATTAAGTTTTATACTATAA

Upstream 100 bases:

>100_bases
TTAATATTTATAAAGAAGAACTCATATTACATATAAAAAAATTTCACTAGTTTTTTTTATTACAAATGAATACCTTTACA
AAACAAAAGGAGGAAGAATA

Downstream 100 bases:

>100_bases
AATGTAAACCAATTCAGCTGGAGTTTTTACTTCAGCTGAATTTTACTTTAATAAAATTAGGCTATGTTTTAGAATAATGC
TGATAATATATCAATTTTTA

Product: gluconate permease

Products: gluconate [Cytoplasm]; L-idonate [Cytoplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MGNTVAGNQMILGLVVGISILVFLILKTKIHTFLALIISAATTGLVGGMPPNKIIDSISKGFGGTLGSIGIIIGFGVMMG
QIFEVSGAAERMARTFIKFLGKKREELALAITGFIVSIPIFCDSGFIILAPLAKAISKKTKKSVVSLGVALGLGLVITHS
LVPPTPGPVGVAGIFGVSVGKFILWGIPLAIPMVIAGMFYGKYIGKKIYQIPGDEEDQWIRTEYQEPVYDFEHEEDNKEL
PSTFMAFAPIMTPIIFILINTILDVLIKQKTITPSGFTNMIQFLGSPIIAVGIGLIIAIYGLAGKLNKEEVINEMEKGIK
SAGIIILVTGGGGALGMVLRDSGTGDYIAKSIAGSHMPVVLIPFIIASLVRLIQGSGTVAMITAASITAPIVAASNVNPI
LAALGACMGSLLFSYFNDSYFWVVNRSLGIKDAKEQIKVWSVTTTIAWAVGLVELIILSFIL

Sequences:

>Translated_462_residues
MGNTVAGNQMILGLVVGISILVFLILKTKIHTFLALIISAATTGLVGGMPPNKIIDSISKGFGGTLGSIGIIIGFGVMMG
QIFEVSGAAERMARTFIKFLGKKREELALAITGFIVSIPIFCDSGFIILAPLAKAISKKTKKSVVSLGVALGLGLVITHS
LVPPTPGPVGVAGIFGVSVGKFILWGIPLAIPMVIAGMFYGKYIGKKIYQIPGDEEDQWIRTEYQEPVYDFEHEEDNKEL
PSTFMAFAPIMTPIIFILINTILDVLIKQKTITPSGFTNMIQFLGSPIIAVGIGLIIAIYGLAGKLNKEEVINEMEKGIK
SAGIIILVTGGGGALGMVLRDSGTGDYIAKSIAGSHMPVVLIPFIIASLVRLIQGSGTVAMITAASITAPIVAASNVNPI
LAALGACMGSLLFSYFNDSYFWVVNRSLGIKDAKEQIKVWSVTTTIAWAVGLVELIILSFIL
>Mature_461_residues
GNTVAGNQMILGLVVGISILVFLILKTKIHTFLALIISAATTGLVGGMPPNKIIDSISKGFGGTLGSIGIIIGFGVMMGQ
IFEVSGAAERMARTFIKFLGKKREELALAITGFIVSIPIFCDSGFIILAPLAKAISKKTKKSVVSLGVALGLGLVITHSL
VPPTPGPVGVAGIFGVSVGKFILWGIPLAIPMVIAGMFYGKYIGKKIYQIPGDEEDQWIRTEYQEPVYDFEHEEDNKELP
STFMAFAPIMTPIIFILINTILDVLIKQKTITPSGFTNMIQFLGSPIIAVGIGLIIAIYGLAGKLNKEEVINEMEKGIKS
AGIIILVTGGGGALGMVLRDSGTGDYIAKSIAGSHMPVVLIPFIIASLVRLIQGSGTVAMITAASITAPIVAASNVNPIL
AALGACMGSLLFSYFNDSYFWVVNRSLGIKDAKEQIKVWSVTTTIAWAVGLVELIILSFIL

Specific function: Transport Of Gluconate And L-Idonate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=450, Percent_Identity=33.3333333333333, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1790716, Length=450, Percent_Identity=31.7777777777778, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI1789097, Length=435, Percent_Identity=33.7931034482759, Blast_Score=215, Evalue=6e-57,
Organism=Escherichia coli, GI1788707, Length=458, Percent_Identity=30.7860262008734, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI48994939, Length=449, Percent_Identity=31.4031180400891, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI2367370, Length=453, Percent_Identity=33.112582781457, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1790776, Length=460, Percent_Identity=30.2173913043478, Blast_Score=196, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 48889; Mature: 48758

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
GNTVAGNQMILGLVVGISILVFLILKTKIHTFLALIISAATTGLVGGMPPNKIIDSISK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH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EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: gluconate [Periplasm]; Proton [Periplasm]; L-idonate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] Proton [Periplasm] + L-idonate [Periplasm] = L-idonate [Cytoplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]