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The map label for this gene is spoIIAB

Identifier: 170757078

GI number: 170757078

Start: 3331623

End: 3332045

Strand: Reverse

Name: spoIIAB

Synonym: CLD_1452

Alternate gene names: 170757078

Gene position: 3332045-3331623 (Counterclockwise)

Preceding gene: 170756243

Following gene: 170754271

Centisome position: 84.18

GC content: 30.02

Gene sequence:

>423_bases
ATGTATGAAAACAAAATGAAAATAGAATTTTTAAGTAAGTCAGAAAATGAAAGTTTTGCTAGAGTATCAGTAGCGGCTTT
TATATCACAGTTAGATCCTACAATAGATGAAATAACAGATGTTAAAACCGCTGTATCAGAGGCAGTTACTAATTCAATAA
TACATGGATATGAAAACAGCAAAAAGGGACTAGTATCTATTGAAAGTGAAATAAAAGGAAGAGAAGTTACAGTAATAATT
TCAGATAATGGTGATGGTATAGATAATATAGAATTAGCTAAACAACCATTGTATACATCAAGACCAGATTTAGAAAGGTC
AGGTATGGGATTTACGGTAATGGAAACATTCATGGATAGTCTTCAAGTTCATTCAGAAAAGGGGAAGGGAACTAAAATAA
TTATGAAAAAGGTTTTTAAATAA

Upstream 100 bases:

>100_bases
GTAAGAAGAGTATTTGAACTTTCAGGTATGTTTAAAATAGTAAATCTTTATGACAGTGTGGATGAAGCCGTAGAAAACTT
ATAATGGGGGGATTTATAAG

Downstream 100 bases:

>100_bases
TTAAGTTAGGTGAATAATATGAATAGTGAAAAGGTAATCATGGAAACTAAAAGTTTTGAAGACAACATGGAACTTATGGA
AAAGGCAAGATCTGGGAATA

Product: anti-sigma F factor

Products: NA

Alternate protein names: Stage II sporulation protein AB [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MYENKMKIEFLSKSENESFARVSVAAFISQLDPTIDEITDVKTAVSEAVTNSIIHGYENSKKGLVSIESEIKGREVTVII
SDNGDGIDNIELAKQPLYTSRPDLERSGMGFTVMETFMDSLQVHSEKGKGTKIIMKKVFK

Sequences:

>Translated_140_residues
MYENKMKIEFLSKSENESFARVSVAAFISQLDPTIDEITDVKTAVSEAVTNSIIHGYENSKKGLVSIESEIKGREVTVII
SDNGDGIDNIELAKQPLYTSRPDLERSGMGFTVMETFMDSLQVHSEKGKGTKIIMKKVFK
>Mature_140_residues
MYENKMKIEFLSKSENESFARVSVAAFISQLDPTIDEITDVKTAVSEAVTNSIIHGYENSKKGLVSIESEIKGREVTVII
SDNGDGIDNIELAKQPLYTSRPDLERSGMGFTVMETFMDSLQVHSEKGKGTKIIMKKVFK

Specific function: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases si

COG id: COG2172

COG function: function code T; Anti-sigma regulatory factor (Ser/Thr protein kinase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anti-sigma-factor family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010194
- InterPro:   IPR003594 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 15583; Mature: 15583

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYENKMKIEFLSKSENESFARVSVAAFISQLDPTIDEITDVKTAVSEAVTNSIIHGYENS
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
KKGLVSIESEIKGREVTVIISDNGDGIDNIELAKQPLYTSRPDLERSGMGFTVMETFMDS
CCCEEEECCCCCCCEEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LQVHSEKGKGTKIIMKKVFK
HHHHCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MYENKMKIEFLSKSENESFARVSVAAFISQLDPTIDEITDVKTAVSEAVTNSIIHGYENS
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
KKGLVSIESEIKGREVTVIISDNGDGIDNIELAKQPLYTSRPDLERSGMGFTVMETFMDS
CCCEEEECCCCCCCEEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LQVHSEKGKGTKIIMKKVFK
HHHHCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA