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The map label for this gene is fabF

Identifier: 170757026

GI number: 170757026

Start: 3913441

End: 3914679

Strand: Reverse

Name: fabF

Synonym: CLD_0887

Alternate gene names: 170757026

Gene position: 3914679-3913441 (Counterclockwise)

Preceding gene: 170754596

Following gene: 170756252

Centisome position: 98.9

GC content: 34.62

Gene sequence:

>1239_bases
ATGAGTAAAAGAGTAGTTATAACGGGAATGGGTGCTATTACCCCTATTGGTAATAGCCTTGAGGAATTTTGGAATAGTAT
AAAAGAGGAAAAAGTAGGTATAGACAATATAAAATCTTTTGATACAGAGAATTATAAAGTTAAGTTAGCGGCAGAAGTCA
AAGATTTTAATCCAGAAGAATATATGGATAAAAAAGAAGCTAGAAGGTTAGATAGATTTTGTCAATTTGCTATAGCAGCA
GCACAACAAGCTGTTGATAATAGTAAATTAGATTTAGATAAAATAAGTAAAGAAAGATTTGGAGTTATAGTAGGTTCAGG
TATTGGTGGATTAGCCACTATAGAAAAGGAAGAACAAAAATTATTAGAAAAGGGACCTAATAGAGTAAGCCCATTGTTTA
TACCAACAATAATAAGTAACATGGCAGCAGGAAATATAGCTATTAGATTTGGAGCTAAGGCTATATGTAATACAGTAGTT
ACAGCTTGCGCTACAGGAACTAATTGTGTAGGTGAAGCTTTCAGGGTTATAAAAAATGGAGAAGCGGATATAATGCTAGC
TGGAGGTACTGAAGCGGCTATAACGCCTATAGCTATAGCAGGTTTTACAACCCTTACAGCTTTAAGTAAAAGCACAGATC
CTAAGAGAGCATCTATACCTTTTGATAAAGAGAGAGACGGATTTGTTATGGGTGAAGGATCAGGAATATTAGTATTAGAA
TCACTAGATCATGCACTAGAAAGAGGTGCTAAAATTTATGGTGAAGTAGTTGGATATGGATCTACTTGTGATGCATATCA
TATGACATCTCCAGCTCCAGGTGGAGAAGGAGCTGCAAGAGCCATAGAGCTTGCCATAAAAGAAGCAGGTATAAATAAAG
AAGAGGTATCCTATATAAATGCTCATGGAACTAGCACTCCATATAATGATAAATTTGAAACAGAAGCAATTAAAAGAGTC
TTTGGAGATTATTCAGCTAGTATACCTGTCAGCTCTACAAAATCTATGATAGGACATTTATTAGGTGCAGCAGGAGCAGT
TGAAGCTATAATATGCGCAAAGTCTTTAGAGGAAGGATATATACCTGCTACAGTTGGATATAATGTTAAGGATGAAGAAT
GTGATTTAGACTATGTGACTTCAGGCGGAAGAAATAAAATAATAGATTATGCTATGTCTAATTCTTTAGGCTTTGGAGGA
CATAATGCAGTAATATTATTAAAAAAATGGGGTGAATAA

Upstream 100 bases:

>100_bases
GCTGTAGGATTTTTAGCTTCAGATAAAGCTTCATATATAACAGGTCAAGTTATACACGTAGATGGCGGAATGATTATATA
GGTAAAAAGAGGTGAATAAT

Downstream 100 bases:

>100_bases
TAAATGGATTTTAAAGGCATAGAAAATTTAATAAAGGCTATGAGTGAGTCAAATTTATCTTCTATGGATATAGAATATAA
TGGTATATCTATAAAAATGA

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MSKRVVITGMGAITPIGNSLEEFWNSIKEEKVGIDNIKSFDTENYKVKLAAEVKDFNPEEYMDKKEARRLDRFCQFAIAA
AQQAVDNSKLDLDKISKERFGVIVGSGIGGLATIEKEEQKLLEKGPNRVSPLFIPTIISNMAAGNIAIRFGAKAICNTVV
TACATGTNCVGEAFRVIKNGEADIMLAGGTEAAITPIAIAGFTTLTALSKSTDPKRASIPFDKERDGFVMGEGSGILVLE
SLDHALERGAKIYGEVVGYGSTCDAYHMTSPAPGGEGAARAIELAIKEAGINKEEVSYINAHGTSTPYNDKFETEAIKRV
FGDYSASIPVSSTKSMIGHLLGAAGAVEAIICAKSLEEGYIPATVGYNVKDEECDLDYVTSGGRNKIIDYAMSNSLGFGG
HNAVILLKKWGE

Sequences:

>Translated_412_residues
MSKRVVITGMGAITPIGNSLEEFWNSIKEEKVGIDNIKSFDTENYKVKLAAEVKDFNPEEYMDKKEARRLDRFCQFAIAA
AQQAVDNSKLDLDKISKERFGVIVGSGIGGLATIEKEEQKLLEKGPNRVSPLFIPTIISNMAAGNIAIRFGAKAICNTVV
TACATGTNCVGEAFRVIKNGEADIMLAGGTEAAITPIAIAGFTTLTALSKSTDPKRASIPFDKERDGFVMGEGSGILVLE
SLDHALERGAKIYGEVVGYGSTCDAYHMTSPAPGGEGAARAIELAIKEAGINKEEVSYINAHGTSTPYNDKFETEAIKRV
FGDYSASIPVSSTKSMIGHLLGAAGAVEAIICAKSLEEGYIPATVGYNVKDEECDLDYVTSGGRNKIIDYAMSNSLGFGG
HNAVILLKKWGE
>Mature_411_residues
SKRVVITGMGAITPIGNSLEEFWNSIKEEKVGIDNIKSFDTENYKVKLAAEVKDFNPEEYMDKKEARRLDRFCQFAIAAA
QQAVDNSKLDLDKISKERFGVIVGSGIGGLATIEKEEQKLLEKGPNRVSPLFIPTIISNMAAGNIAIRFGAKAICNTVVT
ACATGTNCVGEAFRVIKNGEADIMLAGGTEAAITPIAIAGFTTLTALSKSTDPKRASIPFDKERDGFVMGEGSGILVLES
LDHALERGAKIYGEVVGYGSTCDAYHMTSPAPGGEGAARAIELAIKEAGINKEEVSYINAHGTSTPYNDKFETEAIKRVF
GDYSASIPVSSTKSMIGHLLGAAGAVEAIICAKSLEEGYIPATVGYNVKDEECDLDYVTSGGRNKIIDYAMSNSLGFGGH
NAVILLKKWGE

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=420, Percent_Identity=40.7142857142857, Blast_Score=320, Evalue=1e-87,
Organism=Homo sapiens, GI223972627, Length=171, Percent_Identity=40.9356725146199, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI41872631, Length=428, Percent_Identity=24.0654205607477, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1787337, Length=412, Percent_Identity=47.3300970873786, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI1788663, Length=412, Percent_Identity=35.1941747572816, Blast_Score=224, Evalue=9e-60,
Organism=Caenorhabditis elegans, GI71983541, Length=417, Percent_Identity=37.1702637889688, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI71983535, Length=258, Percent_Identity=43.0232558139535, Blast_Score=205, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI212642053, Length=356, Percent_Identity=25.561797752809, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17550940, Length=415, Percent_Identity=24.8192771084337, Blast_Score=95, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6320904, Length=448, Percent_Identity=38.6160714285714, Blast_Score=291, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24644341, Length=423, Percent_Identity=41.1347517730496, Blast_Score=321, Evalue=7e-88,
Organism=Drosophila melanogaster, GI221330659, Length=430, Percent_Identity=24.4186046511628, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI19920632, Length=430, Percent_Identity=24.4186046511628, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24581345, Length=425, Percent_Identity=24.7058823529412, Blast_Score=108, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43962; Mature: 43831

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRVVITGMGAITPIGNSLEEFWNSIKEEKVGIDNIKSFDTENYKVKLAAEVKDFNPEE
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEEEECCCCCHHH
YMDKKEARRLDRFCQFAIAAAQQAVDNSKLDLDKISKERFGVIVGSGIGGLATIEKEEQK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEECCCCCCEECCHHHHH
LLEKGPNRVSPLFIPTIISNMAAGNIAIRFGAKAICNTVVTACATGTNCVGEAFRVIKNG
HHHCCCCCCCCEEHHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
EADIMLAGGTEAAITPIAIAGFTTLTALSKSTDPKRASIPFDKERDGFVMGEGSGILVLE
CCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCEEEEH
SLDHALERGAKIYGEVVGYGSTCDAYHMTSPAPGGEGAARAIELAIKEAGINKEEVSYIN
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHEEEE
AHGTSTPYNDKFETEAIKRVFGDYSASIPVSSTKSMIGHLLGAAGAVEAIICAKSLEEGY
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IPATVGYNVKDEECDLDYVTSGGRNKIIDYAMSNSLGFGGHNAVILLKKWGE
CCEEECCCCCCCCCCCHHCCCCCCCCEEEEHHCCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure 
SKRVVITGMGAITPIGNSLEEFWNSIKEEKVGIDNIKSFDTENYKVKLAAEVKDFNPEE
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEEEECCCCCHHH
YMDKKEARRLDRFCQFAIAAAQQAVDNSKLDLDKISKERFGVIVGSGIGGLATIEKEEQK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEECCCCCCEECCHHHHH
LLEKGPNRVSPLFIPTIISNMAAGNIAIRFGAKAICNTVVTACATGTNCVGEAFRVIKNG
HHHCCCCCCCCEEHHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
EADIMLAGGTEAAITPIAIAGFTTLTALSKSTDPKRASIPFDKERDGFVMGEGSGILVLE
CCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCEEEEH
SLDHALERGAKIYGEVVGYGSTCDAYHMTSPAPGGEGAARAIELAIKEAGINKEEVSYIN
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHEEEE
AHGTSTPYNDKFETEAIKRVFGDYSASIPVSSTKSMIGHLLGAAGAVEAIICAKSLEEGY
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IPATVGYNVKDEECDLDYVTSGGRNKIIDYAMSNSLGFGGHNAVILLKKWGE
CCEEECCCCCCCCCCCHHCCCCCCCCEEEEHHCCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]