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The map label for this gene is coaE

Identifier: 170756834

GI number: 170756834

Start: 3261280

End: 3261918

Strand: Reverse

Name: coaE

Synonym: CLD_1532

Alternate gene names: 170756834

Gene position: 3261918-3261280 (Counterclockwise)

Preceding gene: 170754800

Following gene: 170756009

Centisome position: 82.41

GC content: 25.67

Gene sequence:

>639_bases
ATGTATTGCTTAAAAAGTATTTTTAAAATTGGTCTTACAGGTGGTATAGGTGCTGGTAAAAGTACTATATCAGAAATGAT
AAAAGAAAAAAATATACCAGTAATAGATGCGGATAAAATAAGCAGAGAGGTATTAAAGTTATATCCGGAAATTTTAATAA
GGGTAAAAGAAGTTTTTGGTAAAGAATTTCTAGATGATAATGGCGATTTAAAAAGAAGAGAGTTTGGTAGTTATATATTT
AAAAATAAAAATAAAAGAATAGAATATGAAAATATAATAATGCCTTATATAACAAGAGAAACCTTTAAAAGAATAAAATT
ATTAGAGGAAAATAAAGAATCAATTTGTGTATTAGATGCCCCTACACTAATAGAACAGGGTTTATATAAATATATGGATA
TAAATATATTAGTTTGGGTGGATAAAGATACACAAATAAATAGGGTTGTAAAAAGAGATGGCTTAAATAGAAGTGAAGTT
ATGAATAGAATAAACTCTCAAATGTCTATGGAAGAAAAAAAGAAGTTTGTAGAATATATAATAGATAATTCTAAAGATAT
AGAAAATACAAAGAATGAATTAGATAAGATTTTTATGGAAGTAATGATTAAAGCAAGGCAGAAGGGGGGAGTGCTCTAA

Upstream 100 bases:

>100_bases
TAAAAAAAGAAATGGAACAGGTTTTAGAATTAAAAGTTGGGTTAGACGTGGATATAAATATAGGTAATAATTGGTATGAA
GCAAAGTAAGGAGTTGTTTT

Downstream 100 bases:

>100_bases
TATTAGGGCAAAAAAAAGTGAAGTTTTTAAGAAGACTTTTGATTTTAATATTAACAATTATTTTATTAATAAATATAACA
ACTATAGCAAAATATATTTT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MYCLKSIFKIGLTGGIGAGKSTISEMIKEKNIPVIDADKISREVLKLYPEILIRVKEVFGKEFLDDNGDLKRREFGSYIF
KNKNKRIEYENIIMPYITRETFKRIKLLEENKESICVLDAPTLIEQGLYKYMDINILVWVDKDTQINRVVKRDGLNRSEV
MNRINSQMSMEEKKKFVEYIIDNSKDIENTKNELDKIFMEVMIKARQKGGVL

Sequences:

>Translated_212_residues
MYCLKSIFKIGLTGGIGAGKSTISEMIKEKNIPVIDADKISREVLKLYPEILIRVKEVFGKEFLDDNGDLKRREFGSYIF
KNKNKRIEYENIIMPYITRETFKRIKLLEENKESICVLDAPTLIEQGLYKYMDINILVWVDKDTQINRVVKRDGLNRSEV
MNRINSQMSMEEKKKFVEYIIDNSKDIENTKNELDKIFMEVMIKARQKGGVL
>Mature_212_residues
MYCLKSIFKIGLTGGIGAGKSTISEMIKEKNIPVIDADKISREVLKLYPEILIRVKEVFGKEFLDDNGDLKRREFGSYIF
KNKNKRIEYENIIMPYITRETFKRIKLLEENKESICVLDAPTLIEQGLYKYMDINILVWVDKDTQINRVVKRDGLNRSEV
MNRINSQMSMEEKKKFVEYIIDNSKDIENTKNELDKIFMEVMIKARQKGGVL

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=197, Percent_Identity=34.5177664974619, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI191252795, Length=197, Percent_Identity=34.5177664974619, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI110227607, Length=195, Percent_Identity=26.6666666666667, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI205277394, Length=195, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI110227605, Length=195, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI110227603, Length=195, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI110227601, Length=195, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=9e-17,
Organism=Escherichia coli, GI1786292, Length=200, Percent_Identity=28, Blast_Score=87, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17554944, Length=194, Percent_Identity=34.5360824742268, Blast_Score=134, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI25143409, Length=196, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320402, Length=194, Percent_Identity=31.9587628865979, Blast_Score=104, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24644728, Length=193, Percent_Identity=34.7150259067358, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24658602, Length=197, Percent_Identity=26.3959390862944, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 24817; Mature: 24817

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYCLKSIFKIGLTGGIGAGKSTISEMIKEKNIPVIDADKISREVLKLYPEILIRVKEVFG
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHH
KEFLDDNGDLKRREFGSYIFKNKNKRIEYENIIMPYITRETFKRIKLLEENKESICVLDA
HHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
PTLIEQGLYKYMDINILVWVDKDTQINRVVKRDGLNRSEVMNRINSQMSMEEKKKFVEYI
HHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IDNSKDIENTKNELDKIFMEVMIKARQKGGVL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYCLKSIFKIGLTGGIGAGKSTISEMIKEKNIPVIDADKISREVLKLYPEILIRVKEVFG
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHH
KEFLDDNGDLKRREFGSYIFKNKNKRIEYENIIMPYITRETFKRIKLLEENKESICVLDA
HHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
PTLIEQGLYKYMDINILVWVDKDTQINRVVKRDGLNRSEVMNRINSQMSMEEKKKFVEYI
HHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IDNSKDIENTKNELDKIFMEVMIKARQKGGVL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]