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The map label for this gene is tlpC [H]

Identifier: 170756637

GI number: 170756637

Start: 2987456

End: 2989150

Strand: Reverse

Name: tlpC [H]

Synonym: CLD_1769

Alternate gene names: 170756637

Gene position: 2989150-2987456 (Counterclockwise)

Preceding gene: 170756304

Following gene: 170756680

Centisome position: 75.52

GC content: 26.96

Gene sequence:

>1695_bases
ATGAAACTTAGAAAAAAGCTTGTACTGTCTTTTTCAATAATACTTTTTTTATTTTCTGCAATTATGTTCTCAACGATTTA
TATTACAGTTAATAATATGGCAAATAAAAGTTTCTTGAAAAATATAAAAGATAATGCTAATTTAGGATACTCTTATTTAG
ACTCAAAGTACCCTGGTAAATGGAATATAAAAGGAGACAAGCTTTATAAAGGAGAAGAATTAATTAACAATAATTTTTAT
GTGGTGGATAACATAAAAGAAGAAACAGGAAGCTTAGTAACTATATTTATGAAAGATACTAGAATAGCTACAAATGTAAT
TAGTAATGATGGAAAAAGAGCTGTAGGAACTAAGGCTTCAAAAGAGGTGTTAGAAAAGGTTTTAGATAAAGGTGAAGAGT
TCCAGGGTACTGCAAAGGTAGCTGGTAAGGATGTTTTAACCTACTATAAACCTATAAAAGATTCTAATTCTAAAATTATA
GGTATGTGGTTCATAGGGATAGAGAAAGAAACTATTAAAAAAGAAGTTTGGAAAATATTAAGTTACATTCTTTTTATTAT
ATTAATTGTATTGATTATAGGAATAATACTATTTAACTTTATAGGTAATAGCATAGTTAAAAATATATATTCCTTTAATA
AATATCTTGAAAATATGTCTCAGGGAGACTTTAATAAGGAGTTAAATATTAGATATTTAAAACTAAAAGATGAATTAGGA
CAAATGTTTAATAATTTAGAACATATGCAGATAGCTATAAAGGATATATTAAAGGAAGTAATTACTGATTCAAAAGATTC
TATAAAGTCTAATGAAGATGTATTTATACTTATAAATAAATTATCATCAAATGTAGAGCAAGTTACATCAACTACAGAAG
AAATATCGGCAGCAATGGAGGAAACTGCAGCTTCAGCAGAGGAAATAAACGCTACAGCTAATGAAATAGAAAAATCTATA
GAAGTAATAACTAATAAAATAGGAGAAGCTTATAAAAAATCTGAGGATATAAGTAATAAAGCAAATGAATTAAAAAAGGA
TGCTGAAAACTCTAGAAAAGAAGCCTTTAATTTGTATAAAACTAATGAAAAAGAATTAAGTGAAGCTATAGAAAAATCAA
AATCAGTAGAAAAAATTAATGTATTGTCAGAAGCAATACTTAAAATAACAGAGCAAACAAATCTTTTAGCTTTAAATGCT
GCTATTGAAGCTGCTAGAGCAGGGGAAGCAGGAAAAGGATTTTCAGTGGTAGCAGAGGAAATAAGAAAGCTGGCAGAAGA
ATCTAATAATACAGCTAATGAAATTCAAGAGATTACAAAAATTGTAGTTAATGCAGTAGAAAATTTAGCAAATAACTCTA
ATAAGATATTGACATTTATAGATGGAAAAGTAGTAAAAGACTATGAGAATTTAGTTACTATAGGTGAAATGTATAGTAGT
GATGCAGAATACTATAAAGCTGTATCTGAAAATATAAGTTTCACTACGGAAGAAGTATTAGCTTCTATGAAAAATGTTAT
AGAAGCTATAAATAGTGTGACTATAGCCGCTAATGAAGCAGCAGATGGTACAAGTAATATAGCTAAAAGTGCAAATGATA
TATTAGGAGAAAGCAACAATGTTAAATGTAAATCAGAAGAATCTATGTCTAATTCCCAAAAACTAATAAATTCAATTTCT
AAATTTAAAATATAA

Upstream 100 bases:

>100_bases
TCTTAAATTAAAGCCTATATATTAAAAATATACTAATTAATTCGATATTATATGTATAAATTACTAGAAAAATAATTTAT
ACATATTTAGGAGGTAGGAT

Downstream 100 bases:

>100_bases
AAATTAAAAAGCTATGCATTTGTAATATATGGTTACAAATATATAGCTTTTTAATTTTTAAAATCAATAAATTTATAAAT
TATTTAGTTTATTCATATTT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MKLRKKLVLSFSIILFLFSAIMFSTIYITVNNMANKSFLKNIKDNANLGYSYLDSKYPGKWNIKGDKLYKGEELINNNFY
VVDNIKEETGSLVTIFMKDTRIATNVISNDGKRAVGTKASKEVLEKVLDKGEEFQGTAKVAGKDVLTYYKPIKDSNSKII
GMWFIGIEKETIKKEVWKILSYILFIILIVLIIGIILFNFIGNSIVKNIYSFNKYLENMSQGDFNKELNIRYLKLKDELG
QMFNNLEHMQIAIKDILKEVITDSKDSIKSNEDVFILINKLSSNVEQVTSTTEEISAAMEETAASAEEINATANEIEKSI
EVITNKIGEAYKKSEDISNKANELKKDAENSRKEAFNLYKTNEKELSEAIEKSKSVEKINVLSEAILKITEQTNLLALNA
AIEAARAGEAGKGFSVVAEEIRKLAEESNNTANEIQEITKIVVNAVENLANNSNKILTFIDGKVVKDYENLVTIGEMYSS
DAEYYKAVSENISFTTEEVLASMKNVIEAINSVTIAANEAADGTSNIAKSANDILGESNNVKCKSEESMSNSQKLINSIS
KFKI

Sequences:

>Translated_564_residues
MKLRKKLVLSFSIILFLFSAIMFSTIYITVNNMANKSFLKNIKDNANLGYSYLDSKYPGKWNIKGDKLYKGEELINNNFY
VVDNIKEETGSLVTIFMKDTRIATNVISNDGKRAVGTKASKEVLEKVLDKGEEFQGTAKVAGKDVLTYYKPIKDSNSKII
GMWFIGIEKETIKKEVWKILSYILFIILIVLIIGIILFNFIGNSIVKNIYSFNKYLENMSQGDFNKELNIRYLKLKDELG
QMFNNLEHMQIAIKDILKEVITDSKDSIKSNEDVFILINKLSSNVEQVTSTTEEISAAMEETAASAEEINATANEIEKSI
EVITNKIGEAYKKSEDISNKANELKKDAENSRKEAFNLYKTNEKELSEAIEKSKSVEKINVLSEAILKITEQTNLLALNA
AIEAARAGEAGKGFSVVAEEIRKLAEESNNTANEIQEITKIVVNAVENLANNSNKILTFIDGKVVKDYENLVTIGEMYSS
DAEYYKAVSENISFTTEEVLASMKNVIEAINSVTIAANEAADGTSNIAKSANDILGESNNVKCKSEESMSNSQKLINSIS
KFKI
>Mature_564_residues
MKLRKKLVLSFSIILFLFSAIMFSTIYITVNNMANKSFLKNIKDNANLGYSYLDSKYPGKWNIKGDKLYKGEELINNNFY
VVDNIKEETGSLVTIFMKDTRIATNVISNDGKRAVGTKASKEVLEKVLDKGEEFQGTAKVAGKDVLTYYKPIKDSNSKII
GMWFIGIEKETIKKEVWKILSYILFIILIVLIIGIILFNFIGNSIVKNIYSFNKYLENMSQGDFNKELNIRYLKLKDELG
QMFNNLEHMQIAIKDILKEVITDSKDSIKSNEDVFILINKLSSNVEQVTSTTEEISAAMEETAASAEEINATANEIEKSI
EVITNKIGEAYKKSEDISNKANELKKDAENSRKEAFNLYKTNEKELSEAIEKSKSVEKINVLSEAILKITEQTNLLALNA
AIEAARAGEAGKGFSVVAEEIRKLAEESNNTANEIQEITKIVVNAVENLANNSNKILTFIDGKVVKDYENLVTIGEMYSS
DAEYYKAVSENISFTTEEVLASMKNVIEAINSVTIAANEAADGTSNIAKSANDILGESNNVKCKSEESMSNSQKLINSIS
KFKI

Specific function: Mediates Taxis To The Sugars Ribose And Galactose VIa An Interaction With The Periplasmic Ribose- Or Galactose-Binding Proteins. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of Attractants And Repellents In The Environment, Trans

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=257, Percent_Identity=29.1828793774319, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788195, Length=260, Percent_Identity=29.2307692307692, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788194, Length=358, Percent_Identity=26.536312849162, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789453, Length=373, Percent_Identity=23.5924932975871, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI2367378, Length=267, Percent_Identity=29.5880149812734, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 62990; Mature: 62990

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRKKLVLSFSIILFLFSAIMFSTIYITVNNMANKSFLKNIKDNANLGYSYLDSKYPGK
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCCCCCHHHHCCCCCCC
WNIKGDKLYKGEELINNNFYVVDNIKEETGSLVTIFMKDTRIATNVISNDGKRAVGTKAS
CCCCCCCEECCHHHHCCCCEEEECCHHCCCCEEEEEEECCHHHHHHHCCCCCCCCCCHHH
KEVLEKVLDKGEEFQGTAKVAGKDVLTYYKPIKDSNSKIIGMWFIGIEKETIKKEVWKIL
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHH
SYILFIILIVLIIGIILFNFIGNSIVKNIYSFNKYLENMSQGDFNKELNIRYLKLKDELG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHH
QMFNNLEHMQIAIKDILKEVITDSKDSIKSNEDVFILINKLSSNVEQVTSTTEEISAAME
HHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
ETAASAEEINATANEIEKSIEVITNKIGEAYKKSEDISNKANELKKDAENSRKEAFNLYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TNEKELSEAIEKSKSVEKINVLSEAILKITEQTNLLALNAAIEAARAGEAGKGFSVVAEE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHH
IRKLAEESNNTANEIQEITKIVVNAVENLANNSNKILTFIDGKVVKDYENLVTIGEMYSS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHCC
DAEYYKAVSENISFTTEEVLASMKNVIEAINSVTIAANEAADGTSNIAKSANDILGESNN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHCCCCCC
VKCKSEESMSNSQKLINSISKFKI
CCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLRKKLVLSFSIILFLFSAIMFSTIYITVNNMANKSFLKNIKDNANLGYSYLDSKYPGK
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCCCCCHHHHCCCCCCC
WNIKGDKLYKGEELINNNFYVVDNIKEETGSLVTIFMKDTRIATNVISNDGKRAVGTKAS
CCCCCCCEECCHHHHCCCCEEEECCHHCCCCEEEEEEECCHHHHHHHCCCCCCCCCCHHH
KEVLEKVLDKGEEFQGTAKVAGKDVLTYYKPIKDSNSKIIGMWFIGIEKETIKKEVWKIL
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHH
SYILFIILIVLIIGIILFNFIGNSIVKNIYSFNKYLENMSQGDFNKELNIRYLKLKDELG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHH
QMFNNLEHMQIAIKDILKEVITDSKDSIKSNEDVFILINKLSSNVEQVTSTTEEISAAME
HHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
ETAASAEEINATANEIEKSIEVITNKIGEAYKKSEDISNKANELKKDAENSRKEAFNLYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TNEKELSEAIEKSKSVEKINVLSEAILKITEQTNLLALNAAIEAARAGEAGKGFSVVAEE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHH
IRKLAEESNNTANEIQEITKIVVNAVENLANNSNKILTFIDGKVVKDYENLVTIGEMYSS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHCC
DAEYYKAVSENISFTTEEVLASMKNVIEAINSVTIAANEAADGTSNIAKSANDILGESNN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHCCCCCC
VKCKSEESMSNSQKLINSISKFKI
CCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377 [H]