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The map label for this gene is yabD [H]

Identifier: 170756516

GI number: 170756516

Start: 108923

End: 109717

Strand: Direct

Name: yabD [H]

Synonym: CLD_0709

Alternate gene names: 170756516

Gene position: 108923-109717 (Clockwise)

Preceding gene: 170757504

Following gene: 170757578

Centisome position: 2.75

GC content: 27.8

Gene sequence:

>795_bases
ATGAAAAAATATAGAATATTTGATGCTCATGCCCATTATGATGATGAAGCTTTTGATGAAGATAGAAGTGAAGTTATAAA
AGAACTTGAAGATTTTGGTATATTAGGAGTATTAAATTGTGGTTCTTCTTTAGATACTTCTAAAACATCAGTAGAATTGA
GCAACAAATATAATTTCTTTTATGCAGCAGTAGGCGTGCATCCAGAAAATGCAGAAGAAATTAATGAAAAAACCTTAAAT
AAAATAGAAGCACTATCAGAAAATGAAAAAGTAAAAGCTATAGGAGAAATAGGGCTAGATTATTATTATGAAGAAAATCC
TAAGCGGGATATTCAAATAAAAGCTTTTAAAAAGCAAATGGAATTAGCAGAAAAATTAAACTTACCTGTAGTTATACACG
ATAGAGATGCACATAAAGATACATTAGATATTATAAAACAATTTCCTAATGTAAAAGGAGAAGTGCATTGTTTTTCAGGG
AGTGTAGAGTTTGCTAAGCAATGTGTAGATTTAGGATATTATATAGGGGTTACAGGAGTGGTCACTTTTAAAAATGCTAA
AAAAATAGTAGAAGTTATAAAAAGTGTTCCAATGGATAGAATCTTAGTTGAAACTGATTGCCCATATATGGCTCCTACTC
CTTTAAGAGGTAAAAGGAACAGATCTGAGTATATAAAATATATGATAGATAAGATAGCAGAAATAAAAGAAATAAGTTCT
GAAGAAGTAACTTCACAAATATTAATTAATATAAAAGATCTATTTAATATAGATGTTATAAAAAATAAAGATTAA

Upstream 100 bases:

>100_bases
GAAAAATTTTAATTATAATATATAGAAAATGAAAAATTATTAAGAATATATTAATAAAGTTTAAAGAAAAAATAAAATAT
TGGGATTTGGAGGCAATTCT

Downstream 100 bases:

>100_bases
AAATATGAGAAATATTAATAATCATTTTGAATTTCTCATATATTTTAAATAAATTTATTTTGGAGTATTCCACCGATACC
CTTTATTTAAAAAGCAATTA

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MKKYRIFDAHAHYDDEAFDEDRSEVIKELEDFGILGVLNCGSSLDTSKTSVELSNKYNFFYAAVGVHPENAEEINEKTLN
KIEALSENEKVKAIGEIGLDYYYEENPKRDIQIKAFKKQMELAEKLNLPVVIHDRDAHKDTLDIIKQFPNVKGEVHCFSG
SVEFAKQCVDLGYYIGVTGVVTFKNAKKIVEVIKSVPMDRILVETDCPYMAPTPLRGKRNRSEYIKYMIDKIAEIKEISS
EEVTSQILINIKDLFNIDVIKNKD

Sequences:

>Translated_264_residues
MKKYRIFDAHAHYDDEAFDEDRSEVIKELEDFGILGVLNCGSSLDTSKTSVELSNKYNFFYAAVGVHPENAEEINEKTLN
KIEALSENEKVKAIGEIGLDYYYEENPKRDIQIKAFKKQMELAEKLNLPVVIHDRDAHKDTLDIIKQFPNVKGEVHCFSG
SVEFAKQCVDLGYYIGVTGVVTFKNAKKIVEVIKSVPMDRILVETDCPYMAPTPLRGKRNRSEYIKYMIDKIAEIKEISS
EEVTSQILINIKDLFNIDVIKNKD
>Mature_264_residues
MKKYRIFDAHAHYDDEAFDEDRSEVIKELEDFGILGVLNCGSSLDTSKTSVELSNKYNFFYAAVGVHPENAEEINEKTLN
KIEALSENEKVKAIGEIGLDYYYEENPKRDIQIKAFKKQMELAEKLNLPVVIHDRDAHKDTLDIIKQFPNVKGEVHCFSG
SVEFAKQCVDLGYYIGVTGVVTFKNAKKIVEVIKSVPMDRILVETDCPYMAPTPLRGKRNRSEYIKYMIDKIAEIKEISS
EEVTSQILINIKDLFNIDVIKNKD

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=244, Percent_Identity=31.5573770491803, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI225903439, Length=194, Percent_Identity=35.5670103092784, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI225903424, Length=164, Percent_Identity=37.8048780487805, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI110349734, Length=262, Percent_Identity=27.8625954198473, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI110349730, Length=262, Percent_Identity=27.4809160305344, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI226061853, Length=270, Percent_Identity=27.4074074074074, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI226061614, Length=254, Percent_Identity=25.1968503937008, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI226061595, Length=227, Percent_Identity=26.431718061674, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1787342, Length=261, Percent_Identity=32.9501915708812, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI48994985, Length=259, Percent_Identity=30.8880308880309, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI87082439, Length=257, Percent_Identity=31.1284046692607, Blast_Score=141, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17559024, Length=218, Percent_Identity=33.9449541284404, Blast_Score=132, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17565396, Length=224, Percent_Identity=32.1428571428571, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17543026, Length=241, Percent_Identity=31.9502074688797, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71980746, Length=261, Percent_Identity=25.2873563218391, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24648690, Length=214, Percent_Identity=31.7757009345794, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI221330018, Length=271, Percent_Identity=28.7822878228782, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24586117, Length=271, Percent_Identity=28.7822878228782, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 30198; Mature: 30198

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYRIFDAHAHYDDEAFDEDRSEVIKELEDFGILGVLNCGSSLDTSKTSVELSNKYNFF
CCCEEEEECCCCCCCHHCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEECCCCEEE
YAAVGVHPENAEEINEKTLNKIEALSENEKVKAIGEIGLDYYYEENPKRDIQIKAFKKQM
EEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEECCCCCCCCHHHHHHHHH
ELAEKLNLPVVIHDRDAHKDTLDIIKQFPNVKGEVHCFSGSVEFAKQCVDLGYYIGVTGV
HHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEE
VTFKNAKKIVEVIKSVPMDRILVETDCPYMAPTPLRGKRNRSEYIKYMIDKIAEIKEISS
EEEHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCH
EEVTSQILINIKDLFNIDVIKNKD
HHHHHHHHHHHHHHHEEEEEECCC
>Mature Secondary Structure
MKKYRIFDAHAHYDDEAFDEDRSEVIKELEDFGILGVLNCGSSLDTSKTSVELSNKYNFF
CCCEEEEECCCCCCCHHCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEECCCCEEE
YAAVGVHPENAEEINEKTLNKIEALSENEKVKAIGEIGLDYYYEENPKRDIQIKAFKKQM
EEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEECCCCCCCCHHHHHHHHH
ELAEKLNLPVVIHDRDAHKDTLDIIKQFPNVKGEVHCFSGSVEFAKQCVDLGYYIGVTGV
HHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEE
VTFKNAKKIVEVIKSVPMDRILVETDCPYMAPTPLRGKRNRSEYIKYMIDKIAEIKEISS
EEEHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCH
EEVTSQILINIKDLFNIDVIKNKD
HHHHHHHHHHHHHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]