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The map label for this gene is appC [H]

Identifier: 170756391

GI number: 170756391

Start: 1521478

End: 1522278

Strand: Direct

Name: appC [H]

Synonym: CLD_3180

Alternate gene names: 170756391

Gene position: 1521478-1522278 (Clockwise)

Preceding gene: 170755795

Following gene: 170755429

Centisome position: 38.44

GC content: 31.84

Gene sequence:

>801_bases
ATGAATAAAAAATCTTATAAAATATGGATTATAGTTTTTTCGATAATAATATTAAGTTCTGTTTTTGCACCCATAATAAC
TAAGTTTAATCCTTATGAAGTAGAACTTAAAAAGGTACTTATTAAGCCTAATAAAATACATATAATGGGTACGGATAGTA
TGGGAAGAGATGTGTTTTCGAGGATATTGTATGGTGGAAGGGTCTCTTTAAGTGTGGCTTTATTATCTGTACTGATCTCT
ACTACTATAGGAACATTATATGGAGTTATAAGTGGATACTTTGGTGGGAAAATAGATAGTGTGATGATGAGAATATTAGA
TACATTTTTAGCCATTCCTACATTAGTAATAATGCTTGCGCTTCAATCCATTATAAGAGGGGGAATAACAAGCATGATTA
TAATAATGGGACTTACAGGATGGCTTCAAACTGCAAGAATAGTAAGATCTCAAGTAATGAGTATAAAAAATAAAAATTAT
GTTAAGGCAGCTAGAGTGATTGGAACTCCAATCTATAAGATTATGATAAATCATCTTTTGAGAAATAGTTTGCCAGCTAT
ATTAGTTATATCTGTTTTAAATTGTGCACAGGCTGTCTTCACGGAAGTTTCCATGAGTTTTTTAGGTATAGGAGTACCCG
AGGGAATGCCTTCTTGGGGAAGCATGCTAAACTGTGCTCAAAATGATATACTATCAGGGGCTTGGTGGATAGCTTTTTAT
CCGGGTATATTTACAGTAATATCTATGCTTAGTATAAATTTTATAGGAGAAGGTATTAAGAAAAAATTAGTAGCTTATTA
G

Upstream 100 bases:

>100_bases
GAGCTATATTTATAACTGGAGTTTTAGTTGTTTTATGTATGATAGTTACAGATATAATAGAAATAATAGTTAATCCACAT
CTTAGAAAGTAGGTGCAAAC

Downstream 100 bases:

>100_bases
GGAGAAATTTAATTTTATAAATATACAGTCATTAAACAAGTTTTACAGGTTAAAAGATTTTTGCAAATCATTCATTTAGC
CTTTTAGGAGGAAATAGTTT

Product: peptide/opine/nickel uptake ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MNKKSYKIWIIVFSIIILSSVFAPIITKFNPYEVELKKVLIKPNKIHIMGTDSMGRDVFSRILYGGRVSLSVALLSVLIS
TTIGTLYGVISGYFGGKIDSVMMRILDTFLAIPTLVIMLALQSIIRGGITSMIIIMGLTGWLQTARIVRSQVMSIKNKNY
VKAARVIGTPIYKIMINHLLRNSLPAILVISVLNCAQAVFTEVSMSFLGIGVPEGMPSWGSMLNCAQNDILSGAWWIAFY
PGIFTVISMLSINFIGEGIKKKLVAY

Sequences:

>Translated_266_residues
MNKKSYKIWIIVFSIIILSSVFAPIITKFNPYEVELKKVLIKPNKIHIMGTDSMGRDVFSRILYGGRVSLSVALLSVLIS
TTIGTLYGVISGYFGGKIDSVMMRILDTFLAIPTLVIMLALQSIIRGGITSMIIIMGLTGWLQTARIVRSQVMSIKNKNY
VKAARVIGTPIYKIMINHLLRNSLPAILVISVLNCAQAVFTEVSMSFLGIGVPEGMPSWGSMLNCAQNDILSGAWWIAFY
PGIFTVISMLSINFIGEGIKKKLVAY
>Mature_266_residues
MNKKSYKIWIIVFSIIILSSVFAPIITKFNPYEVELKKVLIKPNKIHIMGTDSMGRDVFSRILYGGRVSLSVALLSVLIS
TTIGTLYGVISGYFGGKIDSVMMRILDTFLAIPTLVIMLALQSIIRGGITSMIIIMGLTGWLQTARIVRSQVMSIKNKNY
VKAARVIGTPIYKIMINHLLRNSLPAILVISVLNCAQAVFTEVSMSFLGIGVPEGMPSWGSMLNCAQNDILSGAWWIAFY
PGIFTVISMLSINFIGEGIKKKLVAY

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=253, Percent_Identity=30.8300395256917, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1787498, Length=265, Percent_Identity=34.7169811320755, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1787054, Length=253, Percent_Identity=30.8300395256917, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1789889, Length=235, Percent_Identity=32.3404255319149, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1789964, Length=254, Percent_Identity=33.0708661417323, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1788505, Length=219, Percent_Identity=31.0502283105023, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1787549, Length=246, Percent_Identity=27.6422764227642, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29306; Mature: 29306

Theoretical pI: Translated: 10.51; Mature: 10.51

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKSYKIWIIVFSIIILSSVFAPIITKFNPYEVELKKVLIKPNKIHIMGTDSMGRDVFS
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHH
RILYGGRVSLSVALLSVLISTTIGTLYGVISGYFGGKIDSVMMRILDTFLAIPTLVIMLA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LQSIIRGGITSMIIIMGLTGWLQTARIVRSQVMSIKNKNYVKAARVIGTPIYKIMINHLL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHH
RNSLPAILVISVLNCAQAVFTEVSMSFLGIGVPEGMPSWGSMLNCAQNDILSGAWWIAFY
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHH
PGIFTVISMLSINFIGEGIKKKLVAY
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKKSYKIWIIVFSIIILSSVFAPIITKFNPYEVELKKVLIKPNKIHIMGTDSMGRDVFS
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHH
RILYGGRVSLSVALLSVLISTTIGTLYGVISGYFGGKIDSVMMRILDTFLAIPTLVIMLA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LQSIIRGGITSMIIIMGLTGWLQTARIVRSQVMSIKNKNYVKAARVIGTPIYKIMINHLL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHH
RNSLPAILVISVLNCAQAVFTEVSMSFLGIGVPEGMPSWGSMLNCAQNDILSGAWWIAFY
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHH
PGIFTVISMLSINFIGEGIKKKLVAY
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]