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The map label for this gene is glnL [H]

Identifier: 170756083

GI number: 170756083

Start: 736251

End: 737063

Strand: Reverse

Name: glnL [H]

Synonym: CLD_0143

Alternate gene names: 170756083

Gene position: 737063-736251 (Counterclockwise)

Preceding gene: 170755300

Following gene: 170757310

Centisome position: 18.62

GC content: 25.83

Gene sequence:

>813_bases
TTGAGAGTATTAATAATAGATGATGACATAAATGTTCATAAGATTCTTAATAAAATAATAAATCATGAATGCCTGGGGGA
AGTAATAAAGGATACTCCCCTAAATGGGGAAGATGGAGGATTTTTAATAGAGAAAGAAAAACCAGATATTGTTATTGTAG
ATCTTTTAATGCCTGGAAAGGATGGTTTAACTTTAGTTAGAGAATATAAATCTAAATACCCTCATATTCAATATATAATG
TTATCCCAAGTATCCTCTAAAGATATGATAGCTAAAGCCTATGAAAATGGAATTGAGTTTTATATAAGTAAACCTATAAA
TGCAGTTGAGGTTAAATCTGTTTTAAAAAAGGTGATTAATAGTGGTATTATGAAAAAAAAATTAGGTAATATAGACTTCA
TATTAAAAAAGGAAGATGAGGATAACTATACATCTAAGATTAAAAGTATAATGAATAAATTAGGCATATTAGGCGAATCA
GGATGCGAAGATATAATAAAAAGTATAGAATTTATAATTGAAAATAATTCTAAAGATACCTATACTCTTAAAGAATTATT
TAAAGAAATATCCGATAAACCCAAATCAATAGAACAAAGAATAAGAAGAACAGCCTTTGTAGCTTTAAATAATATTGCTA
ATTTAGGACTAGAAGATTATATGAATGACATCTTTGTAGAGTTCTCAAATTCTATTTTTAGTTTTGAAGAAGTAAAAAAG
GAAATGGATTATATAAGAGGAAAAAGCTCTGAAAAAGGATCCGTTAATGTTAAAAAATTCTTACAAGGAATAACTTATTA
CATTAATAAATAA

Upstream 100 bases:

>100_bases
AAACCGAGCTAAATGGAATTGTGAAACTAACATCTATAAAAGGAAAAGGTACTAAATTTATGATTTTTATACCCAAAGAT
GTTTTAGAGGGGGAAAGAAT

Downstream 100 bases:

>100_bases
GGTGTATTTGAAATTGTTATAATTATAACAAAATACTTTCTGAAACTTTCCGAAACTTTTTGAAAGCTAGGTTATATAGT
CTAAATAATCAATTAATTCT

Product: response regulator

Products: NADP; 2 glutathione [C]

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MRVLIIDDDINVHKILNKIINHECLGEVIKDTPLNGEDGGFLIEKEKPDIVIVDLLMPGKDGLTLVREYKSKYPHIQYIM
LSQVSSKDMIAKAYENGIEFYISKPINAVEVKSVLKKVINSGIMKKKLGNIDFILKKEDEDNYTSKIKSIMNKLGILGES
GCEDIIKSIEFIIENNSKDTYTLKELFKEISDKPKSIEQRIRRTAFVALNNIANLGLEDYMNDIFVEFSNSIFSFEEVKK
EMDYIRGKSSEKGSVNVKKFLQGITYYINK

Sequences:

>Translated_270_residues
MRVLIIDDDINVHKILNKIINHECLGEVIKDTPLNGEDGGFLIEKEKPDIVIVDLLMPGKDGLTLVREYKSKYPHIQYIM
LSQVSSKDMIAKAYENGIEFYISKPINAVEVKSVLKKVINSGIMKKKLGNIDFILKKEDEDNYTSKIKSIMNKLGILGES
GCEDIIKSIEFIIENNSKDTYTLKELFKEISDKPKSIEQRIRRTAFVALNNIANLGLEDYMNDIFVEFSNSIFSFEEVKK
EMDYIRGKSSEKGSVNVKKFLQGITYYINK
>Mature_270_residues
MRVLIIDDDINVHKILNKIINHECLGEVIKDTPLNGEDGGFLIEKEKPDIVIVDLLMPGKDGLTLVREYKSKYPHIQYIM
LSQVSSKDMIAKAYENGIEFYISKPINAVEVKSVLKKVINSGIMKKKLGNIDFILKKEDEDNYTSKIKSIMNKLGILGES
GCEDIIKSIEFIIENNSKDTYTLKELFKEISDKPKSIEQRIRRTAFVALNNIANLGLEDYMNDIFVEFSNSIFSFEEVKK
EMDYIRGKSSEKGSVNVKKFLQGITYYINK

Specific function: Member of the two-component regulatory system glnL/glnK that positively regulates the expression of the glsA-glnT operon in response to glutamine. GlnL binds the promoter region of glsA- glnT in vitro [H]

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790299, Length=216, Percent_Identity=24.0740740740741, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR013972 [H]

Pfam domain/function: PF00072 Response_reg; PF08664 YcbB [H]

EC number: NA

Molecular weight: Translated: 30894; Mature: 30894

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLIIDDDINVHKILNKIINHECLGEVIKDTPLNGEDGGFLIEKEKPDIVIVDLLMPGK
CEEEEEECCCCHHHHHHHHHCHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEEECCC
DGLTLVREYKSKYPHIQYIMLSQVSSKDMIAKAYENGIEFYISKPINAVEVKSVLKKVIN
CCHHHHHHHHHCCCCEEEHHHHHCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHH
SGIMKKKLGNIDFILKKEDEDNYTSKIKSIMNKLGILGESGCEDIIKSIEFIIENNSKDT
CCHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCH
YTLKELFKEISDKPKSIEQRIRRTAFVALNNIANLGLEDYMNDIFVEFSNSIFSFEEVKK
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHH
EMDYIRGKSSEKGSVNVKKFLQGITYYINK
HHHHHCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVLIIDDDINVHKILNKIINHECLGEVIKDTPLNGEDGGFLIEKEKPDIVIVDLLMPGK
CEEEEEECCCCHHHHHHHHHCHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEEECCC
DGLTLVREYKSKYPHIQYIMLSQVSSKDMIAKAYENGIEFYISKPINAVEVKSVLKKVIN
CCHHHHHHHHHCCCCEEEHHHHHCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHH
SGIMKKKLGNIDFILKKEDEDNYTSKIKSIMNKLGILGESGCEDIIKSIEFIIENNSKDT
CCHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCH
YTLKELFKEISDKPKSIEQRIRRTAFVALNNIANLGLEDYMNDIFVEFSNSIFSFEEVKK
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHH
EMDYIRGKSSEKGSVNVKKFLQGITYYINK
HHHHHCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH2; oxidized glutathione [C]

Specific reaction: NADPH2 + oxidized glutathione = NADP + 2 glutathione [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a disulfide as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8011666; 7704254; 9384377 [H]