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The map label for this gene is mcpB [H]

Identifier: 170756068

GI number: 170756068

Start: 2146622

End: 2148271

Strand: Reverse

Name: mcpB [H]

Synonym: CLD_2624

Alternate gene names: 170756068

Gene position: 2148271-2146622 (Counterclockwise)

Preceding gene: 170754527

Following gene: 170754646

Centisome position: 54.27

GC content: 30.0

Gene sequence:

>1650_bases
ATGTTAAATAGTTTTAAGAAAAAAATATTGGCAGGGTTTTTGTTAGTAACTTTATTGTGTGTTGTTTCTCTGACCACAGT
ATCATTATTAGAGGCTAGAAAAATAGCTACTAATCAAATGAAAAAAGATGGTATTGCCATAAGTAATATGGTAAGAAAAT
CTTTAGGTAAAAATAAAATAACTGATACAAAAGAAATGAGTACTATATTAAAGGAAATAAAAAAAGAGTTAAAAGAAGAT
ATGGTGTATTTATCAGTGTGTAATACAAATTATAAAGTAATTGCTCATAATGATGACAATATGATAAATACTGGAATAGA
GAATAAAGAACAATTTGAAAATATACTCAAAGAAGGAAGAACTATAGGATTAATATTTAAAAGAACAACTGGAGATAAGG
TATATAATGTATCCACCCCATTTTATGAGGATGGGAAAGTAGTAGGCATTATAAATGTAGGAATCTCCCTTGAAGGTGTG
AATAAGTTAATAAAAAAAGGTCTTATTGAAACATTGGGTATAGCCTTGGTAATATTAGTAATTTCCTTTATTATAGCTAT
TTTAATTGCAAGAAATATATCAAAGCCTATAGAAAGTATGGTAACTAAAGTGAATCGAGTTTCTGCGGGGGACTTTACTG
TAGAATTTCATGCAAAGGGTGACGATGAGATTTCCAAATTAATGAGTTCTTTAAATAAAACTATGGAAGTTATAAGAAAT
CTTATAGATAAGATTAAAGATGAAGTAATTACTATAGATGGAGTTTCTCAAAATTTATCTTCATCCAGTGAAGAAAACTC
TGCTTCAACTACTCAGGTTTCAAATTCATTAGCAGAGGTTGCAGAAAGCTCTACAAATCAAGCACAGCAAATTAATGAAG
CTACTGAAGCTCTTATGAGATTTGGAGAACTTCTAGAAAATGTAAATGATAAAGTTATAGATGTAGCCAGTAGCAGTTCA
AATATAAAAAATTCTGCCCATGAGGGTTCTATAAAGATAGACAACCTTGTTAAATCTGTAGAAGACATTAAAGAAAACTT
TCTATCTGTTACAGATAGAATTTCTTCATTAAGTGGTAGTGTTCTTAAAATAAGTGAAATTACAGATGTTATAAATAAAA
TAGCTGAAAAAACTAATCTTTTAGCCTTAAATGCTGCTATAGAAGCAGCTAGAGCTGGCGAAACTGGAAGAGGTTTTTCA
GTGGTGGCAGAAGAAATAAGAAAACTTGCAGAACAGGTTTTATATTCCTCTAAGAATATACATACATTAGTTGAAACTGT
AACAACTAATACAAATGAAGTTTCTTATAATACTGAAAAAGTATCTGAAAAAATACAAGTACAGGCAAATTCCATAGAAG
ATACTATAGATTCTTTTAAAAATATATTAGGAGAAGTGGAAAAGATTACTCCTGAAGTTAAAGAAGTATCCCAAAAATTA
AATATGACTATGGATAAAAAAGATACTATTCTTAATAATGTGGGAACAGTATCTAATATATCTCAAGAACTTTCAGCATC
TACAGAAGAGATTGCTGCGGCCATGGAACAACAAGCTTCTTCTACAGAAGAAGTATCCTCTTCTGCCGAGGAGCTTACAG
AACTAGCAGATAGGTTAGCAACCTTAGTATCAAACTTAAAAACAGAATAG

Upstream 100 bases:

>100_bases
GTATAGATAATGTTAGTATACTTGAAAAAATTTATAAGAGTATTATAATTATAGAAGTTAAGACAGTAATAGATAAAATA
GACAAAAGTAGGTGTAATTT

Downstream 100 bases:

>100_bases
GGGACGGCTTATAAAAATTAATAATTTATAATGATTTTAAAAGGATCGGTTCATTGGGAATAGATAAGAATGTAATACAA
AAGCATAGAAAAATTGAATA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MLNSFKKKILAGFLLVTLLCVVSLTTVSLLEARKIATNQMKKDGIAISNMVRKSLGKNKITDTKEMSTILKEIKKELKED
MVYLSVCNTNYKVIAHNDDNMINTGIENKEQFENILKEGRTIGLIFKRTTGDKVYNVSTPFYEDGKVVGIINVGISLEGV
NKLIKKGLIETLGIALVILVISFIIAILIARNISKPIESMVTKVNRVSAGDFTVEFHAKGDDEISKLMSSLNKTMEVIRN
LIDKIKDEVITIDGVSQNLSSSSEENSASTTQVSNSLAEVAESSTNQAQQINEATEALMRFGELLENVNDKVIDVASSSS
NIKNSAHEGSIKIDNLVKSVEDIKENFLSVTDRISSLSGSVLKISEITDVINKIAEKTNLLALNAAIEAARAGETGRGFS
VVAEEIRKLAEQVLYSSKNIHTLVETVTTNTNEVSYNTEKVSEKIQVQANSIEDTIDSFKNILGEVEKITPEVKEVSQKL
NMTMDKKDTILNNVGTVSNISQELSASTEEIAAAMEQQASSTEEVSSSAEELTELADRLATLVSNLKTE

Sequences:

>Translated_549_residues
MLNSFKKKILAGFLLVTLLCVVSLTTVSLLEARKIATNQMKKDGIAISNMVRKSLGKNKITDTKEMSTILKEIKKELKED
MVYLSVCNTNYKVIAHNDDNMINTGIENKEQFENILKEGRTIGLIFKRTTGDKVYNVSTPFYEDGKVVGIINVGISLEGV
NKLIKKGLIETLGIALVILVISFIIAILIARNISKPIESMVTKVNRVSAGDFTVEFHAKGDDEISKLMSSLNKTMEVIRN
LIDKIKDEVITIDGVSQNLSSSSEENSASTTQVSNSLAEVAESSTNQAQQINEATEALMRFGELLENVNDKVIDVASSSS
NIKNSAHEGSIKIDNLVKSVEDIKENFLSVTDRISSLSGSVLKISEITDVINKIAEKTNLLALNAAIEAARAGETGRGFS
VVAEEIRKLAEQVLYSSKNIHTLVETVTTNTNEVSYNTEKVSEKIQVQANSIEDTIDSFKNILGEVEKITPEVKEVSQKL
NMTMDKKDTILNNVGTVSNISQELSASTEEIAAAMEQQASSTEEVSSSAEELTELADRLATLVSNLKTE
>Mature_549_residues
MLNSFKKKILAGFLLVTLLCVVSLTTVSLLEARKIATNQMKKDGIAISNMVRKSLGKNKITDTKEMSTILKEIKKELKED
MVYLSVCNTNYKVIAHNDDNMINTGIENKEQFENILKEGRTIGLIFKRTTGDKVYNVSTPFYEDGKVVGIINVGISLEGV
NKLIKKGLIETLGIALVILVISFIIAILIARNISKPIESMVTKVNRVSAGDFTVEFHAKGDDEISKLMSSLNKTMEVIRN
LIDKIKDEVITIDGVSQNLSSSSEENSASTTQVSNSLAEVAESSTNQAQQINEATEALMRFGELLENVNDKVIDVASSSS
NIKNSAHEGSIKIDNLVKSVEDIKENFLSVTDRISSLSGSVLKISEITDVINKIAEKTNLLALNAAIEAARAGETGRGFS
VVAEEIRKLAEQVLYSSKNIHTLVETVTTNTNEVSYNTEKVSEKIQVQANSIEDTIDSFKNILGEVEKITPEVKEVSQKL
NMTMDKKDTILNNVGTVSNISQELSASTEEIAAAMEQQASSTEEVSSSAEELTELADRLATLVSNLKTE

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=383, Percent_Identity=27.9373368146214, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI2367378, Length=261, Percent_Identity=28.735632183908, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1788194, Length=374, Percent_Identity=25.1336898395722, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1789453, Length=425, Percent_Identity=23.5294117647059, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788195, Length=284, Percent_Identity=25, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 60013; Mature: 60013

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSFKKKILAGFLLVTLLCVVSLTTVSLLEARKIATNQMKKDGIAISNMVRKSLGKNKI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
TDTKEMSTILKEIKKELKEDMVYLSVCNTNYKVIAHNDDNMINTGIENKEQFENILKEGR
CCHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCC
TIGLIFKRTTGDKVYNVSTPFYEDGKVVGIINVGISLEGVNKLIKKGLIETLGIALVILV
EEEEEEEECCCCEEEECCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ISFIIAILIARNISKPIESMVTKVNRVSAGDFTVEFHAKGDDEISKLMSSLNKTMEVIRN
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
LIDKIKDEVITIDGVSQNLSSSSEENSASTTQVSNSLAEVAESSTNQAQQINEATEALMR
HHHHHHHCEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
FGELLENVNDKVIDVASSSSNIKNSAHEGSIKIDNLVKSVEDIKENFLSVTDRISSLSGS
HHHHHHCCCHHEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VLKISEITDVINKIAEKTNLLALNAAIEAARAGETGRGFSVVAEEIRKLAEQVLYSSKNI
EEHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCH
HTLVETVTTNTNEVSYNTEKVSEKIQVQANSIEDTIDSFKNILGEVEKITPEVKEVSQKL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
NMTMDKKDTILNNVGTVSNISQELSASTEEIAAAMEQQASSTEEVSSSAEELTELADRLA
CCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
TLVSNLKTE
HHHHHHCCC
>Mature Secondary Structure
MLNSFKKKILAGFLLVTLLCVVSLTTVSLLEARKIATNQMKKDGIAISNMVRKSLGKNKI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
TDTKEMSTILKEIKKELKEDMVYLSVCNTNYKVIAHNDDNMINTGIENKEQFENILKEGR
CCHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCC
TIGLIFKRTTGDKVYNVSTPFYEDGKVVGIINVGISLEGVNKLIKKGLIETLGIALVILV
EEEEEEEECCCCEEEECCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ISFIIAILIARNISKPIESMVTKVNRVSAGDFTVEFHAKGDDEISKLMSSLNKTMEVIRN
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
LIDKIKDEVITIDGVSQNLSSSSEENSASTTQVSNSLAEVAESSTNQAQQINEATEALMR
HHHHHHHCEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
FGELLENVNDKVIDVASSSSNIKNSAHEGSIKIDNLVKSVEDIKENFLSVTDRISSLSGS
HHHHHHCCCHHEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VLKISEITDVINKIAEKTNLLALNAAIEAARAGETGRGFSVVAEEIRKLAEQVLYSSKNI
EEHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCH
HTLVETVTTNTNEVSYNTEKVSEKIQVQANSIEDTIDSFKNILGEVEKITPEVKEVSQKL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
NMTMDKKDTILNNVGTVSNISQELSASTEEIAAAMEQQASSTEEVSSSAEELTELADRLA
CCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
TLVSNLKTE
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]