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The map label for this gene is luxS

Identifier: 170755797

GI number: 170755797

Start: 1497348

End: 1497827

Strand: Direct

Name: luxS

Synonym: CLD_3204

Alternate gene names: 170755797

Gene position: 1497348-1497827 (Clockwise)

Preceding gene: 170754799

Following gene: 170756676

Centisome position: 37.83

GC content: 28.54

Gene sequence:

>480_bases
ATGATTAATTTAGAAAAAGCGGGATGGAATTGTGAGGATGTTGGTAATATAGATCATCGTAATGTTAAAGCACCATATAT
TAGAATGATTAATTACAATGAAGGAGAAAATGGAGATGTTGTATTTTCATATGACCTTAGATTAACCCAACCAAATAGTA
GATATATGGATACTAAAGTATTACACTCATTAGAACATTTCATGCTTGTTGGATTCCAAAAATATTTTGACAAAAAATTT
GTAAGTGTTTCTCCAATGGGATGTCAAACAGGATTTTATTTGATTATAATTAACGAATATAATTTTGAAATTATTTCTGA
AAAATTCAAGAAGGTATTAGAAGAAATTCTAGAGGCAGATTCAGTTCCTTTGAGTACGGAAATTACTTGTGGTCAGGCTA
ATCATCATACATTAAAAGAAGTAAAGGAATTAGTAGGAGAGATATTGAAAGAAGAAAAAAATTGGAAGAATGTTATGTAA

Upstream 100 bases:

>100_bases
TATAATCATTCCAGTGTATGGGAAAAGGTCTTATATCAAAGCAAGGAATATTTATTGAGCTGTATTAAATAGATAAATAA
GGTTAGAAAGGAGAAGAAAA

Downstream 100 bases:

>100_bases
TGTAAATGAATAAAATAGGGTATCTTTTATGAATTTAAAATTAATTAATTTGAACTAAAATGTGATTCAAGTAATAATTT
ATTTTCCAATCTATATAATA

Product: S-ribosylhomocysteinase LuxS

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MINLEKAGWNCEDVGNIDHRNVKAPYIRMINYNEGENGDVVFSYDLRLTQPNSRYMDTKVLHSLEHFMLVGFQKYFDKKF
VSVSPMGCQTGFYLIIINEYNFEIISEKFKKVLEEILEADSVPLSTEITCGQANHHTLKEVKELVGEILKEEKNWKNVM

Sequences:

>Translated_159_residues
MINLEKAGWNCEDVGNIDHRNVKAPYIRMINYNEGENGDVVFSYDLRLTQPNSRYMDTKVLHSLEHFMLVGFQKYFDKKF
VSVSPMGCQTGFYLIIINEYNFEIISEKFKKVLEEILEADSVPLSTEITCGQANHHTLKEVKELVGEILKEEKNWKNVM
>Mature_159_residues
MINLEKAGWNCEDVGNIDHRNVKAPYIRMINYNEGENGDVVFSYDLRLTQPNSRYMDTKVLHSLEHFMLVGFQKYFDKKF
VSVSPMGCQTGFYLIIINEYNFEIISEKFKKVLEEILEADSVPLSTEITCGQANHHTLKEVKELVGEILKEEKNWKNVM

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=147, Percent_Identity=27.891156462585, Blast_Score=84, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 18515; Mature: 18515

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLEKAGWNCEDVGNIDHRNVKAPYIRMINYNEGENGDVVFSYDLRLTQPNSRYMDTKV
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEEEECCCCCHHHHHH
LHSLEHFMLVGFQKYFDKKFVSVSPMGCQTGFYLIIINEYNFEIISEKFKKVLEEILEAD
HHHHHHHHHHHHHHHHCCHHEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCC
SVPLSTEITCGQANHHTLKEVKELVGEILKEEKNWKNVM
CCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MINLEKAGWNCEDVGNIDHRNVKAPYIRMINYNEGENGDVVFSYDLRLTQPNSRYMDTKV
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEEEECCCCCHHHHHH
LHSLEHFMLVGFQKYFDKKFVSVSPMGCQTGFYLIIINEYNFEIISEKFKKVLEEILEAD
HHHHHHHHHHHHHHHHCCHHEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCC
SVPLSTEITCGQANHHTLKEVKELVGEILKEEKNWKNVM
CCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]