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The map label for this gene is spoVD [H]

Identifier: 170755690

GI number: 170755690

Start: 2720931

End: 2722601

Strand: Reverse

Name: spoVD [H]

Synonym: CLD_2012

Alternate gene names: 170755690

Gene position: 2722601-2720931 (Counterclockwise)

Preceding gene: 170756729

Following gene: 170757802

Centisome position: 68.78

GC content: 27.17

Gene sequence:

>1671_bases
ATGAGATACAGGGAGAAAAAAAAGGCGTATAAATTATTAACATTATTTATGGTTATATTTTTATTTCTTATATATAGAAT
GGTTAAATTCCAGATTTTTGATGCAGAAAAATTAACTACTATGGCAGAATCTCAATACGCTTATGAAGAAGATACGAAGG
ATAACAAATATAAACTATTGGATACTAAAGGTAACGATTTGCTAAAATATAAAGAAAAATATTATGCTGTCTTAGTGCCA
AGTGCTTTTAAAGATAACAAAGAAGAAAAAGATGAAGAAAAATTGTTAACAATAATGTATATTTTAAGAAATTATAATGA
AAAATATGATATAACCAAAAATCAAACTATAGACAGTAGTGGCAAAAATTACTATGAAATAGATAAAATAACTTATGAAA
AATTAAAAGATATAAAAGGTGTAAAAGGATTTTATACATATAAAAAACAAGAAGTAGATAAGAATATAAATGATAAAAAA
GAAGCATGGAAATTAGAAAATATGCTATTAAATCCTTATAAAAATGATCAAAAAACTTTTAAAGACAAAGAGTCTTTAGA
AATGCGAATATATAATAGAGTAAAAGATAATAAAACATCTAAAATAATATATAAAAAAGATTTACAAGGAGAAATTATAT
CAAAAGAAACAGAAGAGCCCAAATCTAATATAAACCCTAAACTTACATTAGATTCTAAAGTTCAAGATAGTATAAGAAAG
ATTTTAAATAAAAAAGAATATAAGGCTTTTAACCAAGTAGGTGTAATTCTTTCAGAATCAGAGTCTGGAAAGATACGTGC
TATGGTTCAAAAGGATGAAACATTACCTAATGTAAATATAGGGGCCGCTACACAAAATGGATTTCCACCAGGATCTATAT
TTAAAATAATAACAGAAGAAGCTGCATTAGAAAATAATAAAGTATCCTTAAAGGATAGCTTTAAATGTACTGGAGAATTT
GAAAGTAATAAGAAAGGAATTCATGGGAGTTTTAGTACAAAGGAAGCTTTTATAGTTTCTTGTAATGATATTTTTTCACA
GATAGGTAGAAAAGCAGGATTTGAAAATATTGATAATATGGTTAAAAAGCATGGACTATATAGCAAAGTATTAGATTTAC
ACTATGAACAGCAGGGTGCTATTCAAATGGAAAAAGGAGAAAAACCGAATTTAAGTGATGGTACGTTATCTTTAGTGTCC
TTTGGTCAGCTTATTAGAATAACTCCTATAGAAGCAGTTTCTATGGTGAGTACTGTGGTTAATAATGGTGTTTATGTTAA
ACCCTATGTATTAGAATCTTTTGTAGATGATAAAAATAATACAATAGAAGAATTTAATACTACAAAGGAACAAATTATAG
GAATCTATTCCGCAAATAGTCTAAAGGAGCAAATGAAAGAGGTTGTAAAGAGGGGAACGGCAGCTTTAGCTTATGATTCT
AGTATAGAAATTGGAGGAAAAACTGGTACCAATGAAAGGCAAGAAGTTAATGATAAAGGTAAAATGGAGCATCTTTCAGA
TGCCTGGTTTGTAGGATTCTTCAAATCAAACAATAAATATTATACTATGGTAGTATTTATACCTAAGATAAAAACAAAAG
GAGAAAGTGCTGGAACCACCTCAGTACCTATATTTTATGATATAGTTAAAGAAATAAAAGATTCTATTTAA

Upstream 100 bases:

>100_bases
TTGTTGCAAAAATAAAATATTATTTAAAATGAAATAACAATAATTTAGAATAAAACACCTTATTTTGGTTATAATTTAGC
TAAAATGAGGTGTTTTTATT

Downstream 100 bases:

>100_bases
ATCATATATAAAAAATAAAGTATATTTATGTGTACATGTACCTTTCTATCTTAAAGGATATATTATGTTAATAAGCACTA
TTTTAGGTTTGATACCTGCA

Product: penicillin-binding protein

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MRYREKKKAYKLLTLFMVIFLFLIYRMVKFQIFDAEKLTTMAESQYAYEEDTKDNKYKLLDTKGNDLLKYKEKYYAVLVP
SAFKDNKEEKDEEKLLTIMYILRNYNEKYDITKNQTIDSSGKNYYEIDKITYEKLKDIKGVKGFYTYKKQEVDKNINDKK
EAWKLENMLLNPYKNDQKTFKDKESLEMRIYNRVKDNKTSKIIYKKDLQGEIISKETEEPKSNINPKLTLDSKVQDSIRK
ILNKKEYKAFNQVGVILSESESGKIRAMVQKDETLPNVNIGAATQNGFPPGSIFKIITEEAALENNKVSLKDSFKCTGEF
ESNKKGIHGSFSTKEAFIVSCNDIFSQIGRKAGFENIDNMVKKHGLYSKVLDLHYEQQGAIQMEKGEKPNLSDGTLSLVS
FGQLIRITPIEAVSMVSTVVNNGVYVKPYVLESFVDDKNNTIEEFNTTKEQIIGIYSANSLKEQMKEVVKRGTAALAYDS
SIEIGGKTGTNERQEVNDKGKMEHLSDAWFVGFFKSNNKYYTMVVFIPKIKTKGESAGTTSVPIFYDIVKEIKDSI

Sequences:

>Translated_556_residues
MRYREKKKAYKLLTLFMVIFLFLIYRMVKFQIFDAEKLTTMAESQYAYEEDTKDNKYKLLDTKGNDLLKYKEKYYAVLVP
SAFKDNKEEKDEEKLLTIMYILRNYNEKYDITKNQTIDSSGKNYYEIDKITYEKLKDIKGVKGFYTYKKQEVDKNINDKK
EAWKLENMLLNPYKNDQKTFKDKESLEMRIYNRVKDNKTSKIIYKKDLQGEIISKETEEPKSNINPKLTLDSKVQDSIRK
ILNKKEYKAFNQVGVILSESESGKIRAMVQKDETLPNVNIGAATQNGFPPGSIFKIITEEAALENNKVSLKDSFKCTGEF
ESNKKGIHGSFSTKEAFIVSCNDIFSQIGRKAGFENIDNMVKKHGLYSKVLDLHYEQQGAIQMEKGEKPNLSDGTLSLVS
FGQLIRITPIEAVSMVSTVVNNGVYVKPYVLESFVDDKNNTIEEFNTTKEQIIGIYSANSLKEQMKEVVKRGTAALAYDS
SIEIGGKTGTNERQEVNDKGKMEHLSDAWFVGFFKSNNKYYTMVVFIPKIKTKGESAGTTSVPIFYDIVKEIKDSI
>Mature_556_residues
MRYREKKKAYKLLTLFMVIFLFLIYRMVKFQIFDAEKLTTMAESQYAYEEDTKDNKYKLLDTKGNDLLKYKEKYYAVLVP
SAFKDNKEEKDEEKLLTIMYILRNYNEKYDITKNQTIDSSGKNYYEIDKITYEKLKDIKGVKGFYTYKKQEVDKNINDKK
EAWKLENMLLNPYKNDQKTFKDKESLEMRIYNRVKDNKTSKIIYKKDLQGEIISKETEEPKSNINPKLTLDSKVQDSIRK
ILNKKEYKAFNQVGVILSESESGKIRAMVQKDETLPNVNIGAATQNGFPPGSIFKIITEEAALENNKVSLKDSFKCTGEF
ESNKKGIHGSFSTKEAFIVSCNDIFSQIGRKAGFENIDNMVKKHGLYSKVLDLHYEQQGAIQMEKGEKPNLSDGTLSLVS
FGQLIRITPIEAVSMVSTVVNNGVYVKPYVLESFVDDKNNTIEEFNTTKEQIIGIYSANSLKEQMKEVVKRGTAALAYDS
SIEIGGKTGTNERQEVNDKGKMEHLSDAWFVGFFKSNNKYYTMVVFIPKIKTKGESAGTTSVPIFYDIVKEIKDSI

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 63955; Mature: 63955

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYREKKKAYKLLTLFMVIFLFLIYRMVKFQIFDAEKLTTMAESQYAYEEDTKDNKYKLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHCCCCCCCCCCEEEE
DTKGNDLLKYKEKYYAVLVPSAFKDNKEEKDEEKLLTIMYILRNYNEKYDITKNQTIDSS
ECCCCHHHHCCCCEEEEEECCHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GKNYYEIDKITYEKLKDIKGVKGFYTYKKQEVDKNINDKKEAWKLENMLLNPYKNDQKTF
CCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHH
KDKESLEMRIYNRVKDNKTSKIIYKKDLQGEIISKETEEPKSNINPKLTLDSKVQDSIRK
CCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHCCCCCCHHHCCCCEEEECHHHHHHHHH
ILNKKEYKAFNQVGVILSESESGKIRAMVQKDETLPNVNIGAATQNGFPPGSIFKIITEE
HHCHHHHHHHHHHCEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AALENNKVSLKDSFKCTGEFESNKKGIHGSFSTKEAFIVSCNDIFSQIGRKAGFENIDNM
HHHCCCCEEECCCCEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCHHHHHHH
VKKHGLYSKVLDLHYEQQGAIQMEKGEKPNLSDGTLSLVSFGQLIRITPIEAVSMVSTVV
HHHCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHCCEEEECCHHHHHHHHHHH
NNGVYVKPYVLESFVDDKNNTIEEFNTTKEQIIGIYSANSLKEQMKEVVKRGTAALAYDS
HCCEEEEHHHHHHHHCCCCCCHHHHCCCHHHEEEEECHHHHHHHHHHHHHCCCEEEEECC
SIEIGGKTGTNERQEVNDKGKMEHLSDAWFVGFFKSNNKYYTMVVFIPKIKTKGESAGTT
CEEECCCCCCCHHHHCCCCCCHHHCCCCEEEEEEECCCEEEEEEEEEECCCCCCCCCCCC
SVPIFYDIVKEIKDSI
CCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRYREKKKAYKLLTLFMVIFLFLIYRMVKFQIFDAEKLTTMAESQYAYEEDTKDNKYKLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHCCCCCCCCCCEEEE
DTKGNDLLKYKEKYYAVLVPSAFKDNKEEKDEEKLLTIMYILRNYNEKYDITKNQTIDSS
ECCCCHHHHCCCCEEEEEECCHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GKNYYEIDKITYEKLKDIKGVKGFYTYKKQEVDKNINDKKEAWKLENMLLNPYKNDQKTF
CCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHH
KDKESLEMRIYNRVKDNKTSKIIYKKDLQGEIISKETEEPKSNINPKLTLDSKVQDSIRK
CCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHCCCCCCHHHCCCCEEEECHHHHHHHHH
ILNKKEYKAFNQVGVILSESESGKIRAMVQKDETLPNVNIGAATQNGFPPGSIFKIITEE
HHCHHHHHHHHHHCEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AALENNKVSLKDSFKCTGEFESNKKGIHGSFSTKEAFIVSCNDIFSQIGRKAGFENIDNM
HHHCCCCEEECCCCEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCHHHHHHH
VKKHGLYSKVLDLHYEQQGAIQMEKGEKPNLSDGTLSLVSFGQLIRITPIEAVSMVSTVV
HHHCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHCCEEEECCHHHHHHHHHHH
NNGVYVKPYVLESFVDDKNNTIEEFNTTKEQIIGIYSANSLKEQMKEVVKRGTAALAYDS
HCCEEEEHHHHHHHHCCCCCCHHHHCCCHHHEEEEECHHHHHHHHHHHHHCCCEEEEECC
SIEIGGKTGTNERQEVNDKGKMEHLSDAWFVGFFKSNNKYYTMVVFIPKIKTKGESAGTT
CEEECCCCCCCHHHHCCCCCCHHHCCCCEEEEEEECCCEEEEEEEEEECCCCCCCCCCCC
SVPIFYDIVKEIKDSI
CCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]