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The map label for this gene is ytfL [C]

Identifier: 170755576

GI number: 170755576

Start: 3178691

End: 3180010

Strand: Reverse

Name: ytfL [C]

Synonym: CLD_1613

Alternate gene names: 170755576

Gene position: 3180010-3178691 (Counterclockwise)

Preceding gene: 170754893

Following gene: 170757619

Centisome position: 80.34

GC content: 28.18

Gene sequence:

>1320_bases
ATGGAATTGGAACCTGAGCCTGCGAATATAACTTCGCAACTAATGTTAATATTTATTTTAACATTGCTTAATGCATTTTT
CGCATCAGCAGAAATGGCTATAGTATCATTAAACAAAAATAAGATAAAACTTCTTTCAGAAGAAGGAAACAAAAAAGCAA
AACTTTTAGTAAAGCTTATGGATGAACCAACTAAATTTTTATCTACTATACAAGTAGGAATAACCCTTGCTGGTTTTTTT
TCCAGTGCTTCTGCAGCTACTGGAATATCAGAAGACTTAGCACAATATTTGAGCCAACTTAATATTCCTTATAGTAGACA
AATAGCTTTAGTGACAGTAACAATTATATTATCTTATATAACATTGGTGTTTGGAGAATTATTTCCAAAGAGAATAGCAC
TACAAAAATCAGAAACTATAGCATTATTTTCTGTAAGACCTATATTGTATGTATCTAAAATTACAGTTCCATTTGTAAAG
CTACTTTCAGCTTCAACTAATATTTTGGTTAGATTAGTTGGGCTTGATAATGAAGGCTTGGATGAAAAGGTATCAAAAGA
GGAAATTAAATCATTGGTAGAAGTTGGACAAGAAAATGGTGTTATTAATGAAAAAGAAAAAGAAATGATAAATAGTATAT
TTGAGTTTGATGATAAATTAGCAGATGAAGTTATGACACCAAGAACTGAAGTATACTTAATTGATATAGAAAAGCCATTA
AAGGAATATTTAGATGAATTAATAGAAGAAAGATATTCAAGAATACCAGTATATGAGGGGAGCATTGATAATATTATTGG
TATCCTTTATATGAAAGATTTTTTAGGAGAGGCCAGAAAGCATGGCTTTGAGAATGTAGATATTAGAAGTATATTACGTC
CAGCATATTTTGTTCCAGAAACGAAAAATATAGACGACTTATTCAAAGAACTACAAGCATTTAAAAAACATATGGCAATA
TTGATAGATGAATACGGAGGATTTTCAGGAATTGTATCTATAGAAGATCTAATTGAAGAAGTTATGGGCAATATAGAAGA
CGAATATGATGAAGATGAACCAGCCATAAAAAAAATCGATAATGATACTTTTATAATAGATGGTATGGTTTCAATTGATG
ATTTCAATGATTATTTTAATATAGATATTGAAAGCCAAGATTATGATACAATAAATGGATTTTTAATTGACCTTCTTGGA
CGTATTCCGATGAGTGCTGAAGAAAAAAACATAGAATATAAAAATTTTATATTTAAGATAGAAGAAATAAAAGAAAAAAG
AATTAAAAAAATAAAGTTTTATGTTCAAAAAGAAGTTTAA

Upstream 100 bases:

>100_bases
TATATAATATATCAGATATAGATAAGCTGTTATTGTCTTTACTATTTGAATTGTTTATGATATTATTGTCTTAATTTTTT
ATTTAGGGAGGAAATTTATT

Downstream 100 bases:

>100_bases
TTTTAGGGTGTGTAGGTGGATATGTGTAAAAACAAATCTACCTATGTACCCTTTTATTATTCTATAAGATGCAACCAGCT
TATTTAGTATTTACATTGCT

Product: CBS/transporter associated domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MELEPEPANITSQLMLIFILTLLNAFFASAEMAIVSLNKNKIKLLSEEGNKKAKLLVKLMDEPTKFLSTIQVGITLAGFF
SSASAATGISEDLAQYLSQLNIPYSRQIALVTVTIILSYITLVFGELFPKRIALQKSETIALFSVRPILYVSKITVPFVK
LLSASTNILVRLVGLDNEGLDEKVSKEEIKSLVEVGQENGVINEKEKEMINSIFEFDDKLADEVMTPRTEVYLIDIEKPL
KEYLDELIEERYSRIPVYEGSIDNIIGILYMKDFLGEARKHGFENVDIRSILRPAYFVPETKNIDDLFKELQAFKKHMAI
LIDEYGGFSGIVSIEDLIEEVMGNIEDEYDEDEPAIKKIDNDTFIIDGMVSIDDFNDYFNIDIESQDYDTINGFLIDLLG
RIPMSAEEKNIEYKNFIFKIEEIKEKRIKKIKFYVQKEV

Sequences:

>Translated_439_residues
MELEPEPANITSQLMLIFILTLLNAFFASAEMAIVSLNKNKIKLLSEEGNKKAKLLVKLMDEPTKFLSTIQVGITLAGFF
SSASAATGISEDLAQYLSQLNIPYSRQIALVTVTIILSYITLVFGELFPKRIALQKSETIALFSVRPILYVSKITVPFVK
LLSASTNILVRLVGLDNEGLDEKVSKEEIKSLVEVGQENGVINEKEKEMINSIFEFDDKLADEVMTPRTEVYLIDIEKPL
KEYLDELIEERYSRIPVYEGSIDNIIGILYMKDFLGEARKHGFENVDIRSILRPAYFVPETKNIDDLFKELQAFKKHMAI
LIDEYGGFSGIVSIEDLIEEVMGNIEDEYDEDEPAIKKIDNDTFIIDGMVSIDDFNDYFNIDIESQDYDTINGFLIDLLG
RIPMSAEEKNIEYKNFIFKIEEIKEKRIKKIKFYVQKEV
>Mature_439_residues
MELEPEPANITSQLMLIFILTLLNAFFASAEMAIVSLNKNKIKLLSEEGNKKAKLLVKLMDEPTKFLSTIQVGITLAGFF
SSASAATGISEDLAQYLSQLNIPYSRQIALVTVTIILSYITLVFGELFPKRIALQKSETIALFSVRPILYVSKITVPFVK
LLSASTNILVRLVGLDNEGLDEKVSKEEIKSLVEVGQENGVINEKEKEMINSIFEFDDKLADEVMTPRTEVYLIDIEKPL
KEYLDELIEERYSRIPVYEGSIDNIIGILYMKDFLGEARKHGFENVDIRSILRPAYFVPETKNIDDLFKELQAFKKHMAI
LIDEYGGFSGIVSIEDLIEEVMGNIEDEYDEDEPAIKKIDNDTFIIDGMVSIDDFNDYFNIDIESQDYDTINGFLIDLLG
RIPMSAEEKNIEYKNFIFKIEEIKEKRIKKIKFYVQKEV

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=378, Percent_Identity=33.3333333333333, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI40068055, Length=356, Percent_Identity=23.5955056179775, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI40068053, Length=356, Percent_Identity=23.5955056179775, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI94681046, Length=251, Percent_Identity=25.8964143426295, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1790664, Length=426, Percent_Identity=25.1173708920188, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI145693175, Length=419, Percent_Identity=26.491646778043, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1786879, Length=255, Percent_Identity=30.9803921568627, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87082033, Length=341, Percent_Identity=23.1671554252199, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788119, Length=206, Percent_Identity=28.1553398058252, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324512, Length=359, Percent_Identity=22.8412256267409, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 50084; Mature: 50084

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELEPEPANITSQLMLIFILTLLNAFFASAEMAIVSLNKNKIKLLSEEGNKKAKLLVKLM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCCHHHHHHHHHH
DEPTKFLSTIQVGITLAGFFSSASAATGISEDLAQYLSQLNIPYSRQIALVTVTIILSYI
HHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
TLVFGELFPKRIALQKSETIALFSVRPILYVSKITVPFVKLLSASTNILVRLVGLDNEGL
HHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCC
DEKVSKEEIKSLVEVGQENGVINEKEKEMINSIFEFDDKLADEVMTPRTEVYLIDIEKPL
CHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHH
KEYLDELIEERYSRIPVYEGSIDNIIGILYMKDFLGEARKHGFENVDIRSILRPAYFVPE
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHCCCC
TKNIDDLFKELQAFKKHMAILIDEYGGFSGIVSIEDLIEEVMGNIEDEYDEDEPAIKKID
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCHHHHCC
NDTFIIDGMVSIDDFNDYFNIDIESQDYDTINGFLIDLLGRIPMSAEEKNIEYKNFIFKI
CCEEEEECEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
EEIKEKRIKKIKFYVQKEV
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MELEPEPANITSQLMLIFILTLLNAFFASAEMAIVSLNKNKIKLLSEEGNKKAKLLVKLM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCCHHHHHHHHHH
DEPTKFLSTIQVGITLAGFFSSASAATGISEDLAQYLSQLNIPYSRQIALVTVTIILSYI
HHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
TLVFGELFPKRIALQKSETIALFSVRPILYVSKITVPFVKLLSASTNILVRLVGLDNEGL
HHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCC
DEKVSKEEIKSLVEVGQENGVINEKEKEMINSIFEFDDKLADEVMTPRTEVYLIDIEKPL
CHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHH
KEYLDELIEERYSRIPVYEGSIDNIIGILYMKDFLGEARKHGFENVDIRSILRPAYFVPE
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHCCCC
TKNIDDLFKELQAFKKHMAILIDEYGGFSGIVSIEDLIEEVMGNIEDEYDEDEPAIKKID
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCHHHHCC
NDTFIIDGMVSIDDFNDYFNIDIESQDYDTINGFLIDLLGRIPMSAEEKNIEYKNFIFKI
CCEEEEECEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
EEIKEKRIKKIKFYVQKEV
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]