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The map label for this gene is ttcA [H]

Identifier: 170755404

GI number: 170755404

Start: 199610

End: 200332

Strand: Reverse

Name: ttcA [H]

Synonym: CLD_0620

Alternate gene names: 170755404

Gene position: 200332-199610 (Counterclockwise)

Preceding gene: 170756096

Following gene: 170754372

Centisome position: 5.06

GC content: 28.08

Gene sequence:

>723_bases
ATGCAAAAGTTATTAGGAAAGTTTAGAAGAGCAGTAGGAGATTTTAATCTAATACAAAATGGAGATAAAATAGCTGTCGG
TTTATCTGGTGGAAAAGATAGTGTAGTTTTACTTCATCTACTAAAAAAATATCAAAGTTTTTCTCCTGAAAAATTTGATT
TAATAGCTATAACATTAGATACAATGACAGGAGCAGATTTTTCTCCTCTTGAAAATGTATGCTCTAATATAAATGTTCCA
CTATACATATATAAGACCCCTATAAAAGAAATAGTCTTTGATTTAAGAAAAGAAAAAAACCCTTGTTCTTTATGTGCTAA
TTTAAGGAGGGGGGCTTTAAATAATTATTCTAAAGAATTAGGATGTAACAAAATAGCCTTAGGTCATCATAAAAATGATG
CTATAGAAACTTTATTAATGTCTATGTTATATGAAGGAAGGGTAAGTTGCTTTTCCCCAAAGACTTATTTAAATAAAGCC
AACATAACAATAATTAGGCCTATGATATATATAGATGAAATAGCAATTAAAAGTATGATTAAAAGATATGATTTACCTAT
AATTAAAAATCCTTGTCCGGCTAATGGTAACACTAAAAGGCAATATATGAAAGAACTTACCTATACTTTAGAAAAAGATA
TTCCTAAAGTTAAAGACAGACTACTTGGCTGCTTAACCAATATTAATCAAATAAACCTATGGGACAAAGATAAAATCCAA
TAA

Upstream 100 bases:

>100_bases
TTCTCACTATTTTATTTCGATAAATTTATTTGTAATATATATGTATTAATTTATAATATATTTATAATATAAATTTATAC
ATATACTAGGGAGGAATATG

Downstream 100 bases:

>100_bases
TATTTAACTCCTTATATTCATATATATTAATATAAGGAGGGGTGTGTTTTGAATATAGAGAAAACTCATTATATGGAATC
ATTATCTTATTATAAAATAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MQKLLGKFRRAVGDFNLIQNGDKIAVGLSGGKDSVVLLHLLKKYQSFSPEKFDLIAITLDTMTGADFSPLENVCSNINVP
LYIYKTPIKEIVFDLRKEKNPCSLCANLRRGALNNYSKELGCNKIALGHHKNDAIETLLMSMLYEGRVSCFSPKTYLNKA
NITIIRPMIYIDEIAIKSMIKRYDLPIIKNPCPANGNTKRQYMKELTYTLEKDIPKVKDRLLGCLTNINQINLWDKDKIQ

Sequences:

>Translated_240_residues
MQKLLGKFRRAVGDFNLIQNGDKIAVGLSGGKDSVVLLHLLKKYQSFSPEKFDLIAITLDTMTGADFSPLENVCSNINVP
LYIYKTPIKEIVFDLRKEKNPCSLCANLRRGALNNYSKELGCNKIALGHHKNDAIETLLMSMLYEGRVSCFSPKTYLNKA
NITIIRPMIYIDEIAIKSMIKRYDLPIIKNPCPANGNTKRQYMKELTYTLEKDIPKVKDRLLGCLTNINQINLWDKDKIQ
>Mature_240_residues
MQKLLGKFRRAVGDFNLIQNGDKIAVGLSGGKDSVVLLHLLKKYQSFSPEKFDLIAITLDTMTGADFSPLENVCSNINVP
LYIYKTPIKEIVFDLRKEKNPCSLCANLRRGALNNYSKELGCNKIALGHHKNDAIETLLMSMLYEGRVSCFSPKTYLNKA
NITIIRPMIYIDEIAIKSMIKRYDLPIIKNPCPANGNTKRQYMKELTYTLEKDIPKVKDRLLGCLTNINQINLWDKDKIQ

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=246, Percent_Identity=34.5528455284553, Blast_Score=135, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI193211090, Length=225, Percent_Identity=29.7777777777778, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17540090, Length=220, Percent_Identity=28.1818181818182, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24651972, Length=215, Percent_Identity=31.6279069767442, Blast_Score=85, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 27290; Mature: 27290

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLLGKFRRAVGDFNLIQNGDKIAVGLSGGKDSVVLLHLLKKYQSFSPEKFDLIAITLD
CHHHHHHHHHHHCCCHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEE
TMTGADFSPLENVCSNINVPLYIYKTPIKEIVFDLRKEKNPCSLCANLRRGALNNYSKEL
CCCCCCCCHHHHHHCCCCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GCNKIALGHHKNDAIETLLMSMLYEGRVSCFSPKTYLNKANITIIRPMIYIDEIAIKSMI
CCCCEEECCCCHHHHHHHHHHHHHHCCCCEECCHHHHCCCCEEEEHHHHHHHHHHHHHHH
KRYDLPIIKNPCPANGNTKRQYMKELTYTLEKDIPKVKDRLLGCLTNINQINLWDKDKIQ
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEECCCCCCCCC
>Mature Secondary Structure
MQKLLGKFRRAVGDFNLIQNGDKIAVGLSGGKDSVVLLHLLKKYQSFSPEKFDLIAITLD
CHHHHHHHHHHHCCCHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEE
TMTGADFSPLENVCSNINVPLYIYKTPIKEIVFDLRKEKNPCSLCANLRRGALNNYSKEL
CCCCCCCCHHHHHHCCCCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GCNKIALGHHKNDAIETLLMSMLYEGRVSCFSPKTYLNKANITIIRPMIYIDEIAIKSMI
CCCCEEECCCCHHHHHHHHHHHHHHCCCCEECCHHHHCCCCEEEEHHHHHHHHHHHHHHH
KRYDLPIIKNPCPANGNTKRQYMKELTYTLEKDIPKVKDRLLGCLTNINQINLWDKDKIQ
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA