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The map label for this gene is aroC

Identifier: 170755384

GI number: 170755384

Start: 3264575

End: 3265699

Strand: Reverse

Name: aroC

Synonym: CLD_1530

Alternate gene names: 170755384

Gene position: 3265699-3264575 (Counterclockwise)

Preceding gene: 170756162

Following gene: 170754800

Centisome position: 82.5

GC content: 28.89

Gene sequence:

>1125_bases
ATGCTTAGATTTTTAGATGCAGGAGAATCTCATGGAAGGGCATTAACAGCTATAATAGAAGGCATACCATCAAATATTCA
TATAGATATAGATTTTATAAATAAGGAATTAAAAAGAAGACAAACTGGTTATGGTAGAGGAAAGAGAATGTCAATAGAAA
AGGATAAAGTGGAAATATGGTCTGGCATTAGAGAGAATAAGACCACAGGAAATCCTATAACCTTAATTATTTATAATAAA
GATTATCAAAATTGGAAAGAACTTATAAATAAAGAATCAGAAGATAAAGATAAAATTTTTATTCCTAGACCAGGTCATGG
AGATTTAGTGGGACACATTAAATATAATACAGGAGATATAAGAAATGTAATAGAGAGAACTTCAGCTAGAGAAACAGCTA
TTAGAACAGCTGTAGGAGCTATATGTAAATATATATTGAAATTATTAGGAATAGGTATAAGAAGTAAAATTCAGAGTATA
GGAGAAATATTTGATAAGAATGTAGATATATATGATAATAATGTGTATAAAGAAATAGAAGATAGCCCTTTAAGATGTTA
CAATAAAAAAGCAGAAAAGAACATGATAAATGAAATAGATAACTGTAAAAAGGAAGGAGATACTATAGGTGGAAGTATTT
ATGTATCTATAAAGGGCATGCCAGTAGGTATAGGAAGTTATACCCAATGGGATAGAAAATTAGATGCTCTATTAAGTTAT
TCTATTATGTCTGTTCAAGGAATAAAGGCAGTAGAGTTTGGAGAAGGCCTAGATTTAAGTAAAAGAGGAAGTACCTTTAA
TGACGAGATATATTATGATGAAGATAATATAAAAAGAAAAAGCAATAACGCTGGAGGAATTGAAGCTGGCGTATCTAATG
GTGAGGATATAATAGTAAAGGCTTATATGAAACCAATACCATCTATAAAAAAAACTATAAGAACCATTAATTTAAAAGAA
AAAACAAATGTAGAAAATAGATATGAAAGATCTGATGTTTGTGGTGCTGTGCCAGCTTCTATAGTTTTGGAAAATGTATG
TGCCTTTGAAATATTAAAAGAAATTTTGAATACATATCCCTGTGATGATTTCAATATGTTAAAAAAATACATGAGAGAAA
TGTAA

Upstream 100 bases:

>100_bases
AAAAATATCATTGTTTCAAATAATCTTTTAAGTATTAGTAAAATACATTATTAATTTAGTGTATAATAGTTATAGTTTAA
AATATAGGGGAAGTGATACT

Downstream 100 bases:

>100_bases
AATTTGGAGGTTCATTTATGAATAAAGAAAGATTATTAATATTAGATAGTAATAGTTTATTAAATAGAGCTTTTTATGCA
TTACCTGATCTTATGACTGG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MLRFLDAGESHGRALTAIIEGIPSNIHIDIDFINKELKRRQTGYGRGKRMSIEKDKVEIWSGIRENKTTGNPITLIIYNK
DYQNWKELINKESEDKDKIFIPRPGHGDLVGHIKYNTGDIRNVIERTSARETAIRTAVGAICKYILKLLGIGIRSKIQSI
GEIFDKNVDIYDNNVYKEIEDSPLRCYNKKAEKNMINEIDNCKKEGDTIGGSIYVSIKGMPVGIGSYTQWDRKLDALLSY
SIMSVQGIKAVEFGEGLDLSKRGSTFNDEIYYDEDNIKRKSNNAGGIEAGVSNGEDIIVKAYMKPIPSIKKTIRTINLKE
KTNVENRYERSDVCGAVPASIVLENVCAFEILKEILNTYPCDDFNMLKKYMREM

Sequences:

>Translated_374_residues
MLRFLDAGESHGRALTAIIEGIPSNIHIDIDFINKELKRRQTGYGRGKRMSIEKDKVEIWSGIRENKTTGNPITLIIYNK
DYQNWKELINKESEDKDKIFIPRPGHGDLVGHIKYNTGDIRNVIERTSARETAIRTAVGAICKYILKLLGIGIRSKIQSI
GEIFDKNVDIYDNNVYKEIEDSPLRCYNKKAEKNMINEIDNCKKEGDTIGGSIYVSIKGMPVGIGSYTQWDRKLDALLSY
SIMSVQGIKAVEFGEGLDLSKRGSTFNDEIYYDEDNIKRKSNNAGGIEAGVSNGEDIIVKAYMKPIPSIKKTIRTINLKE
KTNVENRYERSDVCGAVPASIVLENVCAFEILKEILNTYPCDDFNMLKKYMREM
>Mature_374_residues
MLRFLDAGESHGRALTAIIEGIPSNIHIDIDFINKELKRRQTGYGRGKRMSIEKDKVEIWSGIRENKTTGNPITLIIYNK
DYQNWKELINKESEDKDKIFIPRPGHGDLVGHIKYNTGDIRNVIERTSARETAIRTAVGAICKYILKLLGIGIRSKIQSI
GEIFDKNVDIYDNNVYKEIEDSPLRCYNKKAEKNMINEIDNCKKEGDTIGGSIYVSIKGMPVGIGSYTQWDRKLDALLSY
SIMSVQGIKAVEFGEGLDLSKRGSTFNDEIYYDEDNIKRKSNNAGGIEAGVSNGEDIIVKAYMKPIPSIKKTIRTINLKE
KTNVENRYERSDVCGAVPASIVLENVCAFEILKEILNTYPCDDFNMLKKYMREM

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=360, Percent_Identity=35.8333333333333, Blast_Score=160, Evalue=9e-41,
Organism=Saccharomyces cerevisiae, GI6321290, Length=377, Percent_Identity=30.2387267904509, Blast_Score=158, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 42388; Mature: 42388

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRFLDAGESHGRALTAIIEGIPSNIHIDIDFINKELKRRQTGYGRGKRMSIEKDKVEIW
CCEECCCCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
SGIRENKTTGNPITLIIYNKDYQNWKELINKESEDKDKIFIPRPGHGDLVGHIKYNTGDI
HCHHCCCCCCCCEEEEEECCCHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEEEECCHHH
RNVIERTSARETAIRTAVGAICKYILKLLGIGIRSKIQSIGEIFDKNVDIYDNNVYKEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEECCCHHHHHC
DSPLRCYNKKAEKNMINEIDNCKKEGDTIGGSIYVSIKGMPVGIGSYTQWDRKLDALLSY
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECEEECCCCCHHHHHHHHHHHHH
SIMSVQGIKAVEFGEGLDLSKRGSTFNDEIYYDEDNIKRKSNNAGGIEAGVSNGEDIIVK
HHHHHCCCEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEECCCCCCCEEEEE
AYMKPIPSIKKTIRTINLKEKTNVENRYERSDVCGAVPASIVLENVCAFEILKEILNTYP
EHHCCCHHHHHHHHHCCCHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
CDDFNMLKKYMREM
CCCHHHHHHHHHCC
>Mature Secondary Structure
MLRFLDAGESHGRALTAIIEGIPSNIHIDIDFINKELKRRQTGYGRGKRMSIEKDKVEIW
CCEECCCCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
SGIRENKTTGNPITLIIYNKDYQNWKELINKESEDKDKIFIPRPGHGDLVGHIKYNTGDI
HCHHCCCCCCCCEEEEEECCCHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEEEECCHHH
RNVIERTSARETAIRTAVGAICKYILKLLGIGIRSKIQSIGEIFDKNVDIYDNNVYKEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEECCCHHHHHC
DSPLRCYNKKAEKNMINEIDNCKKEGDTIGGSIYVSIKGMPVGIGSYTQWDRKLDALLSY
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECEEECCCCCHHHHHHHHHHHHH
SIMSVQGIKAVEFGEGLDLSKRGSTFNDEIYYDEDNIKRKSNNAGGIEAGVSNGEDIIVK
HHHHHCCCEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEECCCCCCCEEEEE
AYMKPIPSIKKTIRTINLKEKTNVENRYERSDVCGAVPASIVLENVCAFEILKEILNTYP
EHHCCCHHHHHHHHHCCCHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
CDDFNMLKKYMREM
CCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA