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The map label for this gene is yfmM [H]

Identifier: 170755278

GI number: 170755278

Start: 1967545

End: 1969101

Strand: Reverse

Name: yfmM [H]

Synonym: CLD_2794

Alternate gene names: 170755278

Gene position: 1969101-1967545 (Counterclockwise)

Preceding gene: 170756324

Following gene: 170754415

Centisome position: 49.75

GC content: 31.21

Gene sequence:

>1557_bases
ATGAGTATATTAACCGTTAAGGATATTAGCCATGGATTTGGAGACAGAGCTATTTTCGAGGAAGTATCCTTTAGACTTTT
AAAAGGAGAGCATGTAGGGCTTATTGGAGCTAATGGAGAGGGTAAGTCTACATTTATGAATATAATAACAGGAAAATTAA
TGCCAGATGAGGGTAAAATTCAATGGGCAAAGGATGTAAGAATAGGCTACATGGATCAGCATTTAAATCTTACAAAGGGA
AAAACCATTAGAGAAGTTTTGAGGGAAGCCTTTGATTATTTATTTAATCTTGAAAAAGAAATGAATGATTTATATATGAA
AATGGGAGAGGTATCCCAGGAAGAAATGGGAAAAATGCTAAATAGAACAGCTACCATACAGGATATGTTAGATCATAATG
ATTTTTACATAATAGATGCTAAAATAGAAGAAATAGCAAGAGGACTTGGCATTGCTGATATAGGTTTAGATAAAGATGTA
TCTGATTTATCTGGAGGACAAAGAACAAAAATACTTCTAGCAAAGCTCCTTTTAGAAAATCCAGATATATTACTTTTAGA
TGAGCCTACAAACTATTTAGACGAAGACCATATAGCATGGCTTAAAAATTATCTTAAAAACTATGAAAATGCCTTTATTC
TAATATCTCATGATATACCATTTTTAAATGAGGTAATAAATTTAATTTATCATGTAGAAAATAAAAGACTTACTCGTTAC
GTAGGGGATTATAATGAATTTAGAAGAGTTTATGAGGAAAACAAGAAACGACTAGAGGCAGCCTATGAAAAGCAACAGAC
AGAAATATCAAAACTAGAAGATTTCATAGCAAAAAATAAAGCAAGAGTTTCCACAGTAGGTATGGCAAGATCTAGACAAA
AAAAATTAGATAAAATAGATAAAATAGAACTTACAAAAGAAAAACCAAAGCCAGAATTTAATTTTAAACAGGCTAGAGCT
TCTGGAAAAGTTATATTTGAAACTAAAGATTTAGTTATAGGCTATGATTCACCTTTAACAAAACCTTTAAATATAAAAAT
AGAAAGAGGACAAAAGGTAGCCTTAGTAGGAGCCAATGGTCTTGGAAAGACTACATTACTAAAAAGTTTATTAGGAGCTA
TAAAACCATTGGAAGGGGATGTTACGCTAGGTGATTATCAATACATAGGATATTTTGAGCAAGAAGAAAGAGAATCTAAT
TATAATACCTGTATAGAAGAAGTGTGGAAAGAGTTCCCTGTATTTACTCAATACGAAATAAGATCTGTTCTAGCAAAATG
TGGATTAACTACGAAGCAATTAGAATCTAAAATAGTAGTACTGTCCGGTGGAGAAGCGGCAAAGGTAAGGCTTTGTAAAA
TACTAAATAGAGAAACCAATATACTAATATTAGACGAACCTACTAACCACTTAGATGTGGAAGCAAAAGAAGAATTAAAA
AGAGCATTAAAAGAATATAAAGGTTCTATACTTTTAGTTTGCCACGAAAAAGAATTTTATGAAGATGTAGTAACAGAAAC
TTGGAATTGTGAAAGTTGGACTACAAAGATTGTGTAA

Upstream 100 bases:

>100_bases
TTAAAAGAAACTAAATTTATATTTTAAATAAATTATTGACAAGGCTTTATTTATAAATTAAAGTTTATTTTAGATTATAT
TTTCAGGAGGATTTTTACAT

Downstream 100 bases:

>100_bases
TATTATAATTGTTTTCACATAAATTATTGTAAATTAATTATATAAATTTGTAATAAAGTACATATTAATGTATAATTTAA
TTATATTAACAATAATTTTA

Product: drug resistance ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MSILTVKDISHGFGDRAIFEEVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLMPDEGKIQWAKDVRIGYMDQHLNLTKG
KTIREVLREAFDYLFNLEKEMNDLYMKMGEVSQEEMGKMLNRTATIQDMLDHNDFYIIDAKIEEIARGLGIADIGLDKDV
SDLSGGQRTKILLAKLLLENPDILLLDEPTNYLDEDHIAWLKNYLKNYENAFILISHDIPFLNEVINLIYHVENKRLTRY
VGDYNEFRRVYEENKKRLEAAYEKQQTEISKLEDFIAKNKARVSTVGMARSRQKKLDKIDKIELTKEKPKPEFNFKQARA
SGKVIFETKDLVIGYDSPLTKPLNIKIERGQKVALVGANGLGKTTLLKSLLGAIKPLEGDVTLGDYQYIGYFEQEERESN
YNTCIEEVWKEFPVFTQYEIRSVLAKCGLTTKQLESKIVVLSGGEAAKVRLCKILNRETNILILDEPTNHLDVEAKEELK
RALKEYKGSILLVCHEKEFYEDVVTETWNCESWTTKIV

Sequences:

>Translated_518_residues
MSILTVKDISHGFGDRAIFEEVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLMPDEGKIQWAKDVRIGYMDQHLNLTKG
KTIREVLREAFDYLFNLEKEMNDLYMKMGEVSQEEMGKMLNRTATIQDMLDHNDFYIIDAKIEEIARGLGIADIGLDKDV
SDLSGGQRTKILLAKLLLENPDILLLDEPTNYLDEDHIAWLKNYLKNYENAFILISHDIPFLNEVINLIYHVENKRLTRY
VGDYNEFRRVYEENKKRLEAAYEKQQTEISKLEDFIAKNKARVSTVGMARSRQKKLDKIDKIELTKEKPKPEFNFKQARA
SGKVIFETKDLVIGYDSPLTKPLNIKIERGQKVALVGANGLGKTTLLKSLLGAIKPLEGDVTLGDYQYIGYFEQEERESN
YNTCIEEVWKEFPVFTQYEIRSVLAKCGLTTKQLESKIVVLSGGEAAKVRLCKILNRETNILILDEPTNHLDVEAKEELK
RALKEYKGSILLVCHEKEFYEDVVTETWNCESWTTKIV
>Mature_517_residues
SILTVKDISHGFGDRAIFEEVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLMPDEGKIQWAKDVRIGYMDQHLNLTKGK
TIREVLREAFDYLFNLEKEMNDLYMKMGEVSQEEMGKMLNRTATIQDMLDHNDFYIIDAKIEEIARGLGIADIGLDKDVS
DLSGGQRTKILLAKLLLENPDILLLDEPTNYLDEDHIAWLKNYLKNYENAFILISHDIPFLNEVINLIYHVENKRLTRYV
GDYNEFRRVYEENKKRLEAAYEKQQTEISKLEDFIAKNKARVSTVGMARSRQKKLDKIDKIELTKEKPKPEFNFKQARAS
GKVIFETKDLVIGYDSPLTKPLNIKIERGQKVALVGANGLGKTTLLKSLLGAIKPLEGDVTLGDYQYIGYFEQEERESNY
NTCIEEVWKEFPVFTQYEIRSVLAKCGLTTKQLESKIVVLSGGEAAKVRLCKILNRETNILILDEPTNHLDVEAKEELKR
ALKEYKGSILLVCHEKEFYEDVVTETWNCESWTTKIV

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=511, Percent_Identity=28.7671232876712, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI10947137, Length=517, Percent_Identity=29.7872340425532, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI27881506, Length=517, Percent_Identity=29.7872340425532, Blast_Score=192, Evalue=7e-49,
Organism=Homo sapiens, GI69354671, Length=518, Percent_Identity=29.5366795366795, Blast_Score=188, Evalue=9e-48,
Organism=Homo sapiens, GI10947135, Length=518, Percent_Identity=29.5366795366795, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI90421313, Length=198, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1787041, Length=510, Percent_Identity=34.3137254901961, Blast_Score=278, Evalue=9e-76,
Organism=Escherichia coli, GI1789751, Length=489, Percent_Identity=29.2433537832311, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1787182, Length=520, Percent_Identity=30.3846153846154, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI2367384, Length=500, Percent_Identity=29.2, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1789891, Length=278, Percent_Identity=25.5395683453237, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788165, Length=256, Percent_Identity=26.171875, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87081782, Length=534, Percent_Identity=23.7827715355805, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788225, Length=191, Percent_Identity=29.8429319371728, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI48994943, Length=232, Percent_Identity=28.0172413793103, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789991, Length=505, Percent_Identity=23.5643564356436, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI48994883, Length=265, Percent_Identity=24.9056603773585, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788506, Length=254, Percent_Identity=24.8031496062992, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788761, Length=178, Percent_Identity=28.6516853932584, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=520, Percent_Identity=28.4615384615385, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17555318, Length=517, Percent_Identity=28.2398452611219, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17553372, Length=511, Percent_Identity=30.1369863013699, Blast_Score=198, Evalue=6e-51,
Organism=Saccharomyces cerevisiae, GI6321121, Length=529, Percent_Identity=32.8922495274102, Blast_Score=248, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6320874, Length=523, Percent_Identity=28.1070745697897, Blast_Score=201, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6325030, Length=399, Percent_Identity=27.0676691729323, Blast_Score=117, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6323278, Length=387, Percent_Identity=27.1317829457364, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6324314, Length=388, Percent_Identity=25.2577319587629, Blast_Score=113, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24666836, Length=523, Percent_Identity=29.0630975143403, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24642252, Length=520, Percent_Identity=30.1923076923077, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI18859989, Length=520, Percent_Identity=30.1923076923077, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24641342, Length=497, Percent_Identity=28.5714285714286, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24661270, Length=483, Percent_Identity=24.0165631469979, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21355589, Length=483, Percent_Identity=24.0165631469979, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28574259, Length=286, Percent_Identity=24.8251748251748, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 59460; Mature: 59329

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILTVKDISHGFGDRAIFEEVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLMPDEGKI
CCEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCE
QWAKDVRIGYMDQHLNLTKGKTIREVLREAFDYLFNLEKEMNDLYMKMGEVSQEEMGKML
EEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NRTATIQDMLDHNDFYIIDAKIEEIARGLGIADIGLDKDVSDLSGGQRTKILLAKLLLEN
HHHHHHHHHHCCCCEEEEECHHHHHHHCCCEEECCCCCCHHHCCCCCHHHHHHHHHHHCC
PDILLLDEPTNYLDEDHIAWLKNYLKNYENAFILISHDIPFLNEVINLIYHVENKRLTRY
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHH
VGDYNEFRRVYEENKKRLEAAYEKQQTEISKLEDFIAKNKARVSTVGMARSRQKKLDKID
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
KIELTKEKPKPEFNFKQARASGKVIFETKDLVIGYDSPLTKPLNIKIERGQKVALVGANG
CEEECCCCCCCCCCHHHHCCCCCEEEEECCEEEECCCCCCCCEEEEEECCCEEEEEECCC
LGKTTLLKSLLGAIKPLEGDVTLGDYQYIGYFEQEERESNYNTCIEEVWKEFPVFTQYEI
CCHHHHHHHHHHHCCCCCCCEEECCEEEECCCCHHHHCCHHHHHHHHHHHHCCCCCHHHH
RSVLAKCGLTTKQLESKIVVLSGGEAAKVRLCKILNRETNILILDEPTNHLDVEAKEELK
HHHHHHCCCCHHHHCCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHH
RALKEYKGSILLVCHEKEFYEDVVTETWNCESWTTKIV
HHHHHHCCCEEEEECCHHHHHHHHHCCCCCCCCEEECC
>Mature Secondary Structure 
SILTVKDISHGFGDRAIFEEVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLMPDEGKI
CEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCE
QWAKDVRIGYMDQHLNLTKGKTIREVLREAFDYLFNLEKEMNDLYMKMGEVSQEEMGKML
EEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NRTATIQDMLDHNDFYIIDAKIEEIARGLGIADIGLDKDVSDLSGGQRTKILLAKLLLEN
HHHHHHHHHHCCCCEEEEECHHHHHHHCCCEEECCCCCCHHHCCCCCHHHHHHHHHHHCC
PDILLLDEPTNYLDEDHIAWLKNYLKNYENAFILISHDIPFLNEVINLIYHVENKRLTRY
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHH
VGDYNEFRRVYEENKKRLEAAYEKQQTEISKLEDFIAKNKARVSTVGMARSRQKKLDKID
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
KIELTKEKPKPEFNFKQARASGKVIFETKDLVIGYDSPLTKPLNIKIERGQKVALVGANG
CEEECCCCCCCCCCHHHHCCCCCEEEEECCEEEECCCCCCCCEEEEEECCCEEEEEECCC
LGKTTLLKSLLGAIKPLEGDVTLGDYQYIGYFEQEERESNYNTCIEEVWKEFPVFTQYEI
CCHHHHHHHHHHHCCCCCCCEEECCEEEECCCCHHHHCCHHHHHHHHHHHHCCCCCHHHH
RSVLAKCGLTTKQLESKIVVLSGGEAAKVRLCKILNRETNILILDEPTNHLDVEAKEELK
HHHHHHCCCCHHHHCCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHH
RALKEYKGSILLVCHEKEFYEDVVTETWNCESWTTKIV
HHHHHHCCCEEEEECCHHHHHHHHHCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]