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The map label for this gene is msrB

Identifier: 170755217

GI number: 170755217

Start: 2469913

End: 2470362

Strand: Reverse

Name: msrB

Synonym: CLD_2297

Alternate gene names: 170755217

Gene position: 2470362-2469913 (Counterclockwise)

Preceding gene: 170756977

Following gene: 170757674

Centisome position: 62.41

GC content: 30.22

Gene sequence:

>450_bases
ATGAATAAAAATTATAGTAAAAAGTCTAAAGAGGAATTAAAAAAGATACTAACACCAGAGGAGTATTATGTTACTCAAGA
AAATGGAACGGAAGCACCATATAAAAATGAGTATTGGGATTTAAATGAAGAAGGAATTTATGTAGATATAACCAATGGAG
AGCCCTTATTTACTTCAAAAGATAAGTTTAATTCTTCATGTGGATGGCCAGCATTTAGCAAGCCTATAGATAGAAAAATA
ATAAAAGAATCTATTGATAAAAGTCATGGAATGACTAGAACAGAAGTAAGAAGTAAAAATGCTGATTCTCATTTAGGTCA
TGTATTTTGTGACGGACCAGAAAAGTTAGGTGGATTAAGATATTGTATTAATTCAGCTTCACTTAAATTTATCCCCAAGA
ACGAGCTTGAAGAAGAAGGGTATGGTGAGTATTTAAAGTTGTTTAAATAA

Upstream 100 bases:

>100_bases
TAAGGCATATTATTATTTTTACTTTATAATAATATATTAAGACATTTATTTAAAGTTTATATAGATTAATCTTTTAAAAA
ATTCAAATCAAGGAGGAAAT

Downstream 100 bases:

>100_bases
TAGTAATAAATTTTATTATTAATTTAAATCAAAATTTTTATTATGAAATTGAAAAAAATAGAGATGGCTAGGAAAAATAA
GTCATATAATATCTAAAAAT

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MNKNYSKKSKEELKKILTPEEYYVTQENGTEAPYKNEYWDLNEEGIYVDITNGEPLFTSKDKFNSSCGWPAFSKPIDRKI
IKESIDKSHGMTRTEVRSKNADSHLGHVFCDGPEKLGGLRYCINSASLKFIPKNELEEEGYGEYLKLFK

Sequences:

>Translated_149_residues
MNKNYSKKSKEELKKILTPEEYYVTQENGTEAPYKNEYWDLNEEGIYVDITNGEPLFTSKDKFNSSCGWPAFSKPIDRKI
IKESIDKSHGMTRTEVRSKNADSHLGHVFCDGPEKLGGLRYCINSASLKFIPKNELEEEGYGEYLKLFK
>Mature_149_residues
MNKNYSKKSKEELKKILTPEEYYVTQENGTEAPYKNEYWDLNEEGIYVDITNGEPLFTSKDKFNSSCGWPAFSKPIDRKI
IKESIDKSHGMTRTEVRSKNADSHLGHVFCDGPEKLGGLRYCINSASLKFIPKNELEEEGYGEYLKLFK

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=126, Percent_Identity=46.8253968253968, Blast_Score=120, Evalue=4e-28,
Organism=Homo sapiens, GI301336162, Length=126, Percent_Identity=46.8253968253968, Blast_Score=120, Evalue=4e-28,
Organism=Homo sapiens, GI73089054, Length=126, Percent_Identity=46.8253968253968, Blast_Score=120, Evalue=4e-28,
Organism=Homo sapiens, GI37620216, Length=126, Percent_Identity=46.8253968253968, Blast_Score=120, Evalue=6e-28,
Organism=Homo sapiens, GI117606353, Length=132, Percent_Identity=44.6969696969697, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788077, Length=125, Percent_Identity=48, Blast_Score=125, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17553450, Length=136, Percent_Identity=46.3235294117647, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI115532676, Length=136, Percent_Identity=46.3235294117647, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6319816, Length=137, Percent_Identity=36.4963503649635, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221378664, Length=123, Percent_Identity=47.9674796747967, Blast_Score=112, Evalue=6e-26,
Organism=Drosophila melanogaster, GI221378662, Length=130, Percent_Identity=46.1538461538462, Blast_Score=112, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24645799, Length=123, Percent_Identity=47.9674796747967, Blast_Score=109, Evalue=6e-25,
Organism=Drosophila melanogaster, GI45553335, Length=123, Percent_Identity=47.9674796747967, Blast_Score=109, Evalue=6e-25,
Organism=Drosophila melanogaster, GI21356369, Length=123, Percent_Identity=47.9674796747967, Blast_Score=109, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24645801, Length=134, Percent_Identity=44.7761194029851, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24645804, Length=135, Percent_Identity=44.4444444444444, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 17188; Mature: 17188

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNYSKKSKEELKKILTPEEYYVTQENGTEAPYKNEYWDLNEEGIYVDITNGEPLFTSK
CCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
DKFNSSCGWPAFSKPIDRKIIKESIDKSHGMTRTEVRSKNADSHLGHVFCDGPEKLGGLR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEECCHHHHCHHH
YCINSASLKFIPKNELEEEGYGEYLKLFK
HHHCCCCEEECCCCCCCCCCCHHHHHHCC
>Mature Secondary Structure
MNKNYSKKSKEELKKILTPEEYYVTQENGTEAPYKNEYWDLNEEGIYVDITNGEPLFTSK
CCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
DKFNSSCGWPAFSKPIDRKIIKESIDKSHGMTRTEVRSKNADSHLGHVFCDGPEKLGGLR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEECCHHHHCHHH
YCINSASLKFIPKNELEEEGYGEYLKLFK
HHHCCCCEEECCCCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA