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The map label for this gene is yxdK [H]

Identifier: 170755192

GI number: 170755192

Start: 2273273

End: 2274292

Strand: Reverse

Name: yxdK [H]

Synonym: CLD_2503

Alternate gene names: 170755192

Gene position: 2274292-2273273 (Counterclockwise)

Preceding gene: 170754214

Following gene: 170756244

Centisome position: 57.46

GC content: 25.78

Gene sequence:

>1020_bases
ATGAGTATAGGTGAATTTATTAAGGATAAAATTCTTATAATATCATGTAATATGCTGATTTTTATTTTATTAGCAATTAT
AATACTTGCTAGTAATGTTGATTTAATTATAATTTTATTTATATTTTGTATATGGTTCTTTCCATTAGTTTCATATATGG
CTTTGGAATTTATAAAATATAAAAATTATTATGATGAAATTGATAGCATATTAGAAAAATTGGACAAGAAATATCTGCTT
CCAGAGCTACTAAAGGAAGCAAGCTTTATTCAAGGAGAAAAGCTTAATTCTATACTTAAAGAGATAAGTAGGGATATGCA
CGAAAATGTAAAATACTATAAAGATATGCAAGAAGATTATAGAGAATATATAGAGGCATGGGTTCATGAAATTAAAACAC
CAATAGCTTCTACAAAATTAATAATTGAAAATAATCGAAATGAAGTAACTAATAAAATAGACTTTCAGATGGATAGAATT
GAGGGGTTTGTAGAACAGGTGCTTTATTATTCGCGAAGCAATAATGTTAGTAAAGATTATATCATAAAACAAATTAATCT
TGATTATGTAGTAAGGAATGTAATTAAAAGAAATTATAGAGATTTTATTCATAAAAAAATAAAATTAGATATAAAAGATA
TAAATGAAATTGTGCACAGTGATGGAAAATGGGTTGAATTTATTATTAATCAGATAATAGTAAATTCTATAAAGTACTCA
AATAGTAAAGAGCCAATGATAAGTATATATTCAACTAAAAAAGCTAATTCAGTAATGTTAACCATAGAGGATAATGGAGC
TGGCATAATAGATAAAGATATAAATAGAGTCTTAGAAAAAGGATTTACCGGTGAGAATGGAAGAAAATTTAGCAAAGGTA
CAGGAATGGGCTTATATCTATGTGAAAAGCTTTGTTCAAAATTAGGGCTAAGAATTAGTATTGATTCTGAGGTAAATAAG
GGAACTAAAGTTACATTAATATTTCCTCTGTCAAGTATGGTAACTTTTGCAGAGGATTAA

Upstream 100 bases:

>100_bases
GCACCTTAACTGTTAATATTAATAGATTAAGAAAGAAGCTTCAAGAAATAGGCATAGAAAATCCAATAGAAACAAGGAGA
GGGTTAGGGTATATAATGCC

Downstream 100 bases:

>100_bases
GGTTTAACAATTCAACTATATTTTACAATATATTGTACTGAATGTATTTTTTTATTAATTTAAAATTTAATTTAATGAGT
TAAAAATTTAAAATATAAAA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSIGEFIKDKILIISCNMLIFILLAIIILASNVDLIIILFIFCIWFFPLVSYMALEFIKYKNYYDEIDSILEKLDKKYLL
PELLKEASFIQGEKLNSILKEISRDMHENVKYYKDMQEDYREYIEAWVHEIKTPIASTKLIIENNRNEVTNKIDFQMDRI
EGFVEQVLYYSRSNNVSKDYIIKQINLDYVVRNVIKRNYRDFIHKKIKLDIKDINEIVHSDGKWVEFIINQIIVNSIKYS
NSKEPMISIYSTKKANSVMLTIEDNGAGIIDKDINRVLEKGFTGENGRKFSKGTGMGLYLCEKLCSKLGLRISIDSEVNK
GTKVTLIFPLSSMVTFAED

Sequences:

>Translated_339_residues
MSIGEFIKDKILIISCNMLIFILLAIIILASNVDLIIILFIFCIWFFPLVSYMALEFIKYKNYYDEIDSILEKLDKKYLL
PELLKEASFIQGEKLNSILKEISRDMHENVKYYKDMQEDYREYIEAWVHEIKTPIASTKLIIENNRNEVTNKIDFQMDRI
EGFVEQVLYYSRSNNVSKDYIIKQINLDYVVRNVIKRNYRDFIHKKIKLDIKDINEIVHSDGKWVEFIINQIIVNSIKYS
NSKEPMISIYSTKKANSVMLTIEDNGAGIIDKDINRVLEKGFTGENGRKFSKGTGMGLYLCEKLCSKLGLRISIDSEVNK
GTKVTLIFPLSSMVTFAED
>Mature_338_residues
SIGEFIKDKILIISCNMLIFILLAIIILASNVDLIIILFIFCIWFFPLVSYMALEFIKYKNYYDEIDSILEKLDKKYLLP
ELLKEASFIQGEKLNSILKEISRDMHENVKYYKDMQEDYREYIEAWVHEIKTPIASTKLIIENNRNEVTNKIDFQMDRIE
GFVEQVLYYSRSNNVSKDYIIKQINLDYVVRNVIKRNYRDFIHKKIKLDIKDINEIVHSDGKWVEFIINQIIVNSIKYSN
SKEPMISIYSTKKANSVMLTIEDNGAGIIDKDINRVLEKGFTGENGRKFSKGTGMGLYLCEKLCSKLGLRISIDSEVNKG
TKVTLIFPLSSMVTFAED

Specific function: Probable member of the two-component regulatory system yxdK/yxdJ. May activate yxdJ in response to the antibacterial protein LL-37 [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39512; Mature: 39381

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIGEFIKDKILIISCNMLIFILLAIIILASNVDLIIILFIFCIWFFPLVSYMALEFIKY
CCHHHHHHCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNYYDEIDSILEKLDKKYLLPELLKEASFIQGEKLNSILKEISRDMHENVKYYKDMQEDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REYIEAWVHEIKTPIASTKLIIENNRNEVTNKIDFQMDRIEGFVEQVLYYSRSNNVSKDY
HHHHHHHHHHHHCCHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IIKQINLDYVVRNVIKRNYRDFIHKKIKLDIKDINEIVHSDGKWVEFIINQIIVNSIKYS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
NSKEPMISIYSTKKANSVMLTIEDNGAGIIDKDINRVLEKGFTGENGRKFSKGTGMGLYL
CCCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
CEKLCSKLGLRISIDSEVNKGTKVTLIFPLSSMVTFAED
HHHHHHHCCCEEEECCCCCCCCEEEEEEEHHHHHHHCCC
>Mature Secondary Structure 
SIGEFIKDKILIISCNMLIFILLAIIILASNVDLIIILFIFCIWFFPLVSYMALEFIKY
CHHHHHHCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNYYDEIDSILEKLDKKYLLPELLKEASFIQGEKLNSILKEISRDMHENVKYYKDMQEDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REYIEAWVHEIKTPIASTKLIIENNRNEVTNKIDFQMDRIEGFVEQVLYYSRSNNVSKDY
HHHHHHHHHHHHCCHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IIKQINLDYVVRNVIKRNYRDFIHKKIKLDIKDINEIVHSDGKWVEFIINQIIVNSIKYS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
NSKEPMISIYSTKKANSVMLTIEDNGAGIIDKDINRVLEKGFTGENGRKFSKGTGMGLYL
CCCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
CEKLCSKLGLRISIDSEVNKGTKVTLIFPLSSMVTFAED
HHHHHHHCCCEEEECCCCCCCCEEEEEEEHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7952181; 9384377; 8867804 [H]