Click here to switch to the map view.

The map label for this gene is pdxA

Identifier: 170754968

GI number: 170754968

Start: 2400223

End: 2401227

Strand: Reverse

Name: pdxA

Synonym: CLD_2369

Alternate gene names: 170754968

Gene position: 2401227-2400223 (Counterclockwise)

Preceding gene: 170756854

Following gene: 170757705

Centisome position: 60.66

GC content: 32.44

Gene sequence:

>1005_bases
ATGATTAATAATAAACCAATAATAGGAATACCTATAGGAGATCCAGCCGGTGTAGGGCCAGAAATAGTAGTAAAATCATT
AACTGAAGCGGAAGTTTATGAAAAATGTAATCCTATATTAATAGGAGATGCAAAAGTAATTAAACAAGCTATGGGATTCT
GCAATGTTAATTTAAATATAAATTCAATTAAAAAAGCAGATGAGGGTAAGTTTACTTTAGGAACTATAGATTTGATAGAT
TTAAATAATATAGACATCGATGAATTAAAAATAGGTAAGGTTCAAGGTATAGCAGGAAAAGCAGCCTTTGAATATATAAA
AAAATCTGTAGAAATGGCTAAAGAGGGAGAGCTAGATGCTATAGCTACAACTCCAATAAATAAAGAGTCCTTAAGAGAAG
GTAATGTAAATTATATCGGTCATACTGAGATTTTAGCAGATTTAACAGATACAGAAGATCCTCTTACTATGTTTGAAGTT
AGAGGAATGAGGGTATTCTTCTTAACAAGACATGTTTCTTTAAGAAAAGCTTGTGACTTAGTAACTAAAGAAAGAGTATT
AGATTATATAATAAGATGTTCCGAGGCTTTAGAAAAACTAGGAGTAAAGGATGGGAAGATGGCTGTTGCAGGGTTAAATC
CTCATAGTGGAGAACATGGCTTATTTGGGGATGAAGAAATGAAAGCTGTTGTTCCAGCTATAGAGGAAGCTCAAAAAATG
GGATACAAAGTAGAAGGTCCTATAGGAGCAGATTCGGTATTCCATTTAGCTCTTAAGGGAAGATATAATTCAGTATTATC
TTTGTATCATGATCAAGGTCATATAGCAACAAAAACATTAGATTTTGAAAGAACTATTGCTGTAACAAATGGAATGCCAA
TACTTAGAACTTCAGTAGATCATGGAACTGCCTTTGATATAGCAGGTACTGGACAAGCTAGTTCTGTAAGTATGGTAGAA
GCTATAGTTTTAGCAGCTAAATATTCACCTAAATTTAAAAAATAA

Upstream 100 bases:

>100_bases
AATTGTAAGCAAAGGGGGAATGGTAGGAAAAGAAGATGGAATGGAATTATGTGTAGATTATTTATTTAAAAATATTAATT
GTGACTAGGGAGGACTAAAT

Downstream 100 bases:

>100_bases
ATTTTATTAATAGCTATAATAAATAAGAGTTCTTACTTATAAAGCAATTACAATCTTTGGCAGTTTCTTATCTTCATCCT
ATAGAATATGGAGGTAAGAA

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MINNKPIIGIPIGDPAGVGPEIVVKSLTEAEVYEKCNPILIGDAKVIKQAMGFCNVNLNINSIKKADEGKFTLGTIDLID
LNNIDIDELKIGKVQGIAGKAAFEYIKKSVEMAKEGELDAIATTPINKESLREGNVNYIGHTEILADLTDTEDPLTMFEV
RGMRVFFLTRHVSLRKACDLVTKERVLDYIIRCSEALEKLGVKDGKMAVAGLNPHSGEHGLFGDEEMKAVVPAIEEAQKM
GYKVEGPIGADSVFHLALKGRYNSVLSLYHDQGHIATKTLDFERTIAVTNGMPILRTSVDHGTAFDIAGTGQASSVSMVE
AIVLAAKYSPKFKK

Sequences:

>Translated_334_residues
MINNKPIIGIPIGDPAGVGPEIVVKSLTEAEVYEKCNPILIGDAKVIKQAMGFCNVNLNINSIKKADEGKFTLGTIDLID
LNNIDIDELKIGKVQGIAGKAAFEYIKKSVEMAKEGELDAIATTPINKESLREGNVNYIGHTEILADLTDTEDPLTMFEV
RGMRVFFLTRHVSLRKACDLVTKERVLDYIIRCSEALEKLGVKDGKMAVAGLNPHSGEHGLFGDEEMKAVVPAIEEAQKM
GYKVEGPIGADSVFHLALKGRYNSVLSLYHDQGHIATKTLDFERTIAVTNGMPILRTSVDHGTAFDIAGTGQASSVSMVE
AIVLAAKYSPKFKK
>Mature_334_residues
MINNKPIIGIPIGDPAGVGPEIVVKSLTEAEVYEKCNPILIGDAKVIKQAMGFCNVNLNINSIKKADEGKFTLGTIDLID
LNNIDIDELKIGKVQGIAGKAAFEYIKKSVEMAKEGELDAIATTPINKESLREGNVNYIGHTEILADLTDTEDPLTMFEV
RGMRVFFLTRHVSLRKACDLVTKERVLDYIIRCSEALEKLGVKDGKMAVAGLNPHSGEHGLFGDEEMKAVVPAIEEAQKM
GYKVEGPIGADSVFHLALKGRYNSVLSLYHDQGHIATKTLDFERTIAVTNGMPILRTSVDHGTAFDIAGTGQASSVSMVE
AIVLAAKYSPKFKK

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=329, Percent_Identity=29.1793313069909, Blast_Score=157, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 36259; Mature: 36259

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINNKPIIGIPIGDPAGVGPEIVVKSLTEAEVYEKCNPILIGDAKVIKQAMGFCNVNLNI
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCEEEEEEEH
NSIKKADEGKFTLGTIDLIDLNNIDIDELKIGKVQGIAGKAAFEYIKKSVEMAKEGELDA
HHCCCCCCCCEEEEEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCE
IATTPINKESLREGNVNYIGHTEILADLTDTEDPLTMFEVRGMRVFFLTRHVSLRKACDL
EEECCCCHHHHHCCCCCEEECHHHEEECCCCCCCEEEEEECCEEEEEEEHHHHHHHHHHH
VTKERVLDYIIRCSEALEKLGVKDGKMAVAGLNPHSGEHGLFGDEEMKAVVPAIEEAQKM
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GYKVEGPIGADSVFHLALKGRYNSVLSLYHDQGHIATKTLDFERTIAVTNGMPILRTSVD
CEEEECCCCCCCEEEEEECCCHHHHHHEEECCCCEEEEEECCCEEEEEECCCEEEEEECC
HGTAFDIAGTGQASSVSMVEAIVLAAKYSPKFKK
CCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MINNKPIIGIPIGDPAGVGPEIVVKSLTEAEVYEKCNPILIGDAKVIKQAMGFCNVNLNI
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCEEEEEEEH
NSIKKADEGKFTLGTIDLIDLNNIDIDELKIGKVQGIAGKAAFEYIKKSVEMAKEGELDA
HHCCCCCCCCEEEEEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCE
IATTPINKESLREGNVNYIGHTEILADLTDTEDPLTMFEVRGMRVFFLTRHVSLRKACDL
EEECCCCHHHHHCCCCCEEECHHHEEECCCCCCCEEEEEECCEEEEEEEHHHHHHHHHHH
VTKERVLDYIIRCSEALEKLGVKDGKMAVAGLNPHSGEHGLFGDEEMKAVVPAIEEAQKM
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GYKVEGPIGADSVFHLALKGRYNSVLSLYHDQGHIATKTLDFERTIAVTNGMPILRTSVD
CEEEECCCCCCCEEEEEECCCHHHHHHEEECCCCEEEEEECCCEEEEEECCCEEEEEECC
HGTAFDIAGTGQASSVSMVEAIVLAAKYSPKFKK
CCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA