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The map label for this gene is resE [H]

Identifier: 170754768

GI number: 170754768

Start: 1151378

End: 1152733

Strand: Direct

Name: resE [H]

Synonym: CLD_3522

Alternate gene names: 170754768

Gene position: 1151378-1152733 (Clockwise)

Preceding gene: 170757255

Following gene: 170756466

Centisome position: 29.09

GC content: 28.02

Gene sequence:

>1356_bases
GTGCATACAATAAGAAAAAGATTAAGTATTTTATTTGTTATTTGCTCAGTAGCAGGAATATTGCTTGTTACATTGTTTGT
AAATGCAACTATAAATAACAAATTTGATGCATATATAGTGGATGTCCAAGATAAAAGATATCAAAGAATAGTATCTTACT
TTGAAGAAGTATATAAAGCACAAGGAAAGTGGACTAAAAATTCTGGTGTTGAGTTGATGCATGAAGCTCATATGGGAAAT
TATTGTTTAACACTTCTAGATATTAATAAAAAAACTATATGGGGTATGAACCCAAATGATATAAGATTAAATACAATGCC
TGTAAAGGATAGAGGTGTTTATAATACTAAGACTTTTGAAATTAAATCAGAAGGTAAAGTAGTTGGATATGTGGGGATTG
GACAGTATTCCTCTTTACTATTATCTGAAGAAGATATAAGTTTTAAAACATCTATAAATAAAAGTATTGTTGCTAGTGGA
ATTCTAACTCTTGTTATTATAATTACCATAAGTCTTTACTTTTCCAAACAATTCTCAATTCCAATTAAGGAGGTTGCTAA
TTTGTCTGTAAATTTATCAAAAGGAGATTTTGATGGGAAATCAAGTGTTGAAAGTAATATTGAAGAGCTAGAGAATTTAA
GAGAAAGTGTTAATATACTAGCTGAAAAATTAAAGTATCAAGATTCTCTAAGAAGAAGATTAGTTTCTGACATATTCCAT
GAGATTAGAACTCCATTAAATGTATTGCAAAATAACCTAGAGGCAATGATAGATGGAGTTTTACCTGTTACAGAAGAAAG
ATTAAATTGTCTGAATGAAGAAGTAGTTAGATTTGGTAGATTATTAAATAACTTAAATGTATTAAAAGAGTTTGAATCTG
AGAGTATTAAGCTTAATTTCCAAAAAATATTTTTAGATGAATTAATTGCAGATATATGTAGTGATTTTTATGCAATAGCA
GAAAACAAGAATATTAAACTGCAATACCATATAGAAAATCATGAGGATTATAGTATAACTGGAGATAGAGATAGATTAAA
ACAAGTATTTATAAATTTACTTTCTAATGCTCTTAAATTTACAGAAGATGGCGGAGAGGTACTAATTAAAATATATAAAA
GTGATAAAAACATTGTTGTAGAAGTTAAGGATAATGGTGTAGGAATTAAGAAGGAAGATTTGCCTTTTATATTTGAAAGA
CTTTATAGGGGAGATAAGAGTAGACACCAATTTAAAGGGAATGGTATAGGGCTAACTATTGTGAAAAATATATTGCAGCT
CCATTATGCAAGTATAGATCTTGAAAGTGAAGAAGGTGAAGGAACTACTTTTAAGGTCTATTTTCATAGAATGTAA

Upstream 100 bases:

>100_bases
TATAAAGAATATTCGTAAAAAGATAGAAGAAGATACTAAGAATCCTAAATATATTGTTACAGTTATGAAGGTAGGTTATA
AATTTGGTGGTGAAAATTAA

Downstream 100 bases:

>100_bases
ATAACTAATAAAAGTACAAATAAATTTTAGAAGTATTATGGAGAAATGAGAGATCCTTAAATTATAAAGTATTATTCAAA
AACACGTTTGGGGGAAGATC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MHTIRKRLSILFVICSVAGILLVTLFVNATINNKFDAYIVDVQDKRYQRIVSYFEEVYKAQGKWTKNSGVELMHEAHMGN
YCLTLLDINKKTIWGMNPNDIRLNTMPVKDRGVYNTKTFEIKSEGKVVGYVGIGQYSSLLLSEEDISFKTSINKSIVASG
ILTLVIIITISLYFSKQFSIPIKEVANLSVNLSKGDFDGKSSVESNIEELENLRESVNILAEKLKYQDSLRRRLVSDIFH
EIRTPLNVLQNNLEAMIDGVLPVTEERLNCLNEEVVRFGRLLNNLNVLKEFESESIKLNFQKIFLDELIADICSDFYAIA
ENKNIKLQYHIENHEDYSITGDRDRLKQVFINLLSNALKFTEDGGEVLIKIYKSDKNIVVEVKDNGVGIKKEDLPFIFER
LYRGDKSRHQFKGNGIGLTIVKNILQLHYASIDLESEEGEGTTFKVYFHRM

Sequences:

>Translated_451_residues
MHTIRKRLSILFVICSVAGILLVTLFVNATINNKFDAYIVDVQDKRYQRIVSYFEEVYKAQGKWTKNSGVELMHEAHMGN
YCLTLLDINKKTIWGMNPNDIRLNTMPVKDRGVYNTKTFEIKSEGKVVGYVGIGQYSSLLLSEEDISFKTSINKSIVASG
ILTLVIIITISLYFSKQFSIPIKEVANLSVNLSKGDFDGKSSVESNIEELENLRESVNILAEKLKYQDSLRRRLVSDIFH
EIRTPLNVLQNNLEAMIDGVLPVTEERLNCLNEEVVRFGRLLNNLNVLKEFESESIKLNFQKIFLDELIADICSDFYAIA
ENKNIKLQYHIENHEDYSITGDRDRLKQVFINLLSNALKFTEDGGEVLIKIYKSDKNIVVEVKDNGVGIKKEDLPFIFER
LYRGDKSRHQFKGNGIGLTIVKNILQLHYASIDLESEEGEGTTFKVYFHRM
>Mature_451_residues
MHTIRKRLSILFVICSVAGILLVTLFVNATINNKFDAYIVDVQDKRYQRIVSYFEEVYKAQGKWTKNSGVELMHEAHMGN
YCLTLLDINKKTIWGMNPNDIRLNTMPVKDRGVYNTKTFEIKSEGKVVGYVGIGQYSSLLLSEEDISFKTSINKSIVASG
ILTLVIIITISLYFSKQFSIPIKEVANLSVNLSKGDFDGKSSVESNIEELENLRESVNILAEKLKYQDSLRRRLVSDIFH
EIRTPLNVLQNNLEAMIDGVLPVTEERLNCLNEEVVRFGRLLNNLNVLKEFESESIKLNFQKIFLDELIADICSDFYAIA
ENKNIKLQYHIENHEDYSITGDRDRLKQVFINLLSNALKFTEDGGEVLIKIYKSDKNIVVEVKDNGVGIKKEDLPFIFER
LYRGDKSRHQFKGNGIGLTIVKNILQLHYASIDLESEEGEGTTFKVYFHRM

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=255, Percent_Identity=34.5098039215686, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1786783, Length=296, Percent_Identity=27.7027027027027, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786600, Length=220, Percent_Identity=30.9090909090909, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI145693157, Length=236, Percent_Identity=27.1186440677966, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=29.045643153527, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788713, Length=226, Percent_Identity=30.9734513274336, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789149, Length=259, Percent_Identity=23.1660231660232, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790346, Length=295, Percent_Identity=24.406779661017, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082128, Length=291, Percent_Identity=22.680412371134, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789403, Length=312, Percent_Identity=25.6410256410256, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=27.0386266094421, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790551, Length=299, Percent_Identity=26.7558528428094, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787894, Length=289, Percent_Identity=24.9134948096886, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786912, Length=227, Percent_Identity=25.5506607929515, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790861, Length=249, Percent_Identity=24.8995983935743, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788549, Length=215, Percent_Identity=25.1162790697674, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788279, Length=252, Percent_Identity=23.015873015873, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081816, Length=213, Percent_Identity=25.3521126760563, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51666; Mature: 51666

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTIRKRLSILFVICSVAGILLVTLFVNATINNKFDAYIVDVQDKRYQRIVSYFEEVYKA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
QGKWTKNSGVELMHEAHMGNYCLTLLDINKKTIWGMNPNDIRLNTMPVKDRGVYNTKTFE
CCCCCCCCCHHHHHHHCCCCEEEEEEECCCCEEECCCCCCEEEEEECCCCCCCCCCEEEE
IKSEGKVVGYVGIGQYSSLLLSEEDISFKTSINKSIVASGILTLVIIITISLYFSKQFSI
EECCCCEEEEEECCCHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PIKEVANLSVNLSKGDFDGKSSVESNIEELENLRESVNILAEKLKYQDSLRRRLVSDIFH
CHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIRTPLNVLQNNLEAMIDGVLPVTEERLNCLNEEVVRFGRLLNNLNVLKEFESESIKLNF
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHH
QKIFLDELIADICSDFYAIAENKNIKLQYHIENHEDYSITGDRDRLKQVFINLLSNALKF
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHC
TEDGGEVLIKIYKSDKNIVVEVKDNGVGIKKEDLPFIFERLYRGDKSRHQFKGNGIGLTI
CCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHHCCCCCEEHHH
VKNILQLHYASIDLESEEGEGTTFKVYFHRM
HHHHHHHHHHHEEEECCCCCCCEEEEEEECC
>Mature Secondary Structure
MHTIRKRLSILFVICSVAGILLVTLFVNATINNKFDAYIVDVQDKRYQRIVSYFEEVYKA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
QGKWTKNSGVELMHEAHMGNYCLTLLDINKKTIWGMNPNDIRLNTMPVKDRGVYNTKTFE
CCCCCCCCCHHHHHHHCCCCEEEEEEECCCCEEECCCCCCEEEEEECCCCCCCCCCEEEE
IKSEGKVVGYVGIGQYSSLLLSEEDISFKTSINKSIVASGILTLVIIITISLYFSKQFSI
EECCCCEEEEEECCCHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PIKEVANLSVNLSKGDFDGKSSVESNIEELENLRESVNILAEKLKYQDSLRRRLVSDIFH
CHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIRTPLNVLQNNLEAMIDGVLPVTEERLNCLNEEVVRFGRLLNNLNVLKEFESESIKLNF
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHH
QKIFLDELIADICSDFYAIAENKNIKLQYHIENHEDYSITGDRDRLKQVFINLLSNALKF
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHC
TEDGGEVLIKIYKSDKNIVVEVKDNGVGIKKEDLPFIFERLYRGDKSRHQFKGNGIGLTI
CCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHHCCCCCEEHHH
VKNILQLHYASIDLESEEGEGTTFKVYFHRM
HHHHHHHHHHHEEEECCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]